Vitamin D increases tight-junction conductance and paracellular Ca2+ transport in Caco-2 cell cultures

American Journal of Physiology - Gastrointestinal and Liver Physiology

Volumn 274, Issue 2 37-2, 1998, Pages

  Chirayath, Mary V ^a,b   Gajdzik, Leszek ^a   Hulla, Wolfgang ^a   Graf, Jürg ^a   Cross, Heide S ^a   Peterlik, Meinrad ^a,c  

^a UNIVERSITY OF VIENNA   (Austria)

^b PSG Coll of Technology   (India)

^c Dept of Gen and Exp Pathology ^*  (Austria)

Author keywords

1 ,25 dihydroxyvitamin D3; Calbindin 9kDa; Calcium adenosinetriphosphatase; Cellular calcium uptake; Genomic action; Intestinal calcium absorption; Ionic conductance; Synthetic vitamin D compounds; Vitamin D receptor

Indexed keywords

22 OXACALCITRIOL; ADENOSINE TRIPHOSPHATASE (CALCIUM); CALBINDIN; CALCIUM; VITAMIN D; VITAMIN D DERIVATIVE; VITAMIN D RECEPTOR;

ARTICLE; CALCIUM TRANSPORT; CELL CULTURE; ELECTRIC RESISTANCE; HUMAN; HUMAN CELL; INTESTINE CELL; ION PERMEABILITY; MEMBRANE CONDUCTANCE; PRIORITY JOURNAL; TIGHT JUNCTION;

EID: 0031888728     PISSN: 01931857     EISSN: None     Source Type: Journal    
DOI: 10.1152/ajpgi.1998.274.2.g389     Document Type: Article

References (15)

1. Andersen, J. M., and C. M. Van Itallie. Tight junctions and the molecular basis for regulation of paracellular permeability. Am. J. Physiol. 269 (Gastrointest. Liver Physiol. 32): G467-G475, 1995.
2. Ausubel, F. M., R. Brent, R. E. Kingston, D. D. Moore, J. G. Seidman, J. A. Smith, and K. Struhl. Current Protocols in Molecular Biology. New York: Wiley, 1994, vol. 1.
3. Beaulieu, J.-F., and A. Quaroni. Clonal analysis of sucrase-isomaltase expression in the human colon adenocarcinoma Caco-2 cells. Biochem. J. 280: 599-608, 1991
4. Bindels, R. J. M., J. A. H. Timmermans, A. Hartog, and C. H. van Os. Transcellular calcium transport across cultured intestinal and renal cells. In: Extra- and Intracellular Calcium and Phosphate Regulation: From Basic Research to Clinical Medicine, edited by F. Bronner and M. Peterlik. Boca Raton, FL: CRC, 1992 p. 9-20
5. 3 analogs: structure-function relationships. J. Pharmacol. Exp. Ther. 275: 1254-1260, 1995.
6. 3 and its analogs. J. Bone Miner. Res. 9: 1277-1288, 1994.
7. Boland, A. R., and I. Nemere. Rapid actions of vitamin D compounds. J. Cell. Biochem. 49: 32-36, 1992.
8. Bronner, F. Intestinal calcium transport: the cellular pathway. Miner. Electrolyte Metab. 16: 94-100, 1990.
9. Candeliere, G. A., J. Prud'homme, and R. St.-Arnaud. Differential stimulation of Fos and Jun family members by calcitriol in osteoblastic cells. Mol. Endocrinol. 5: 1780-1788, 1991.
10. Chirayath, M. V., W. Hulla, W.-M. Tong, H. S. Cross, and M. Peterlik. Differential expression of genomic vitamin D effects in Caco-2 cells. Calcif. Tissue Int. 56: 469, 1995
11. Chomczinski, P., and N. Sacchi. Single-step method of RNA isolation by acid guanidinium thiocyanate-phenol-chloroform extraction. Anal. Biochem. 162: 156-159, 1987
12. Cross, H. S., R. A. Corradino, and M. Peterlik. Calcitriol-dependent, paracellular sodium transport in the embryonic chick intestine. Mol. Cell. Endocrinol. 53: 53-58, 1987
13. Cross, H. S., and M. Peterlik. Differentiation-dependent expression of calcitriol actions on absorptive processes in cultured chick intestine: modulation by triiodothyronine. Acta Endocrinol. 124: 679-684, 1991.
14. 3-1α-hydroxylase activity and regulation of side-chain metabolism. J. Steroid Biochem. Mol. Biol. 62: 21-28, 1997.
15. 3 in rat osteosarcoma cells: structure-function studies using ligand analogs. Endocrinology 129: 1876-1884, 1991.