Persistent chlamydial envelope antigens in antibiotic-exposed infected cells trigger neutrophil chemotaxis

Journal of Infectious Diseases

Volumn 179, Issue 4, 1999, Pages 954-966

  Wyrick, Priscilla B ^a   Knight, Stephen T ^b   Paul, Terry R ^b   Rank, Roger G ^b   Barbier, Claire S ^b  

^a UNIVERSITY OF NORTH CAROLINA SCHOOL OF MEDICINE   (United States)

^b NONE

Author keywords

[No Author keywords available]

Indexed keywords

AZITHROMYCIN; BACTERIAL ANTIGEN; BACTERIUM LIPOPOLYSACCHARIDE; CHEMOKINE; ENVELOPE PROTEIN; INTERLEUKIN 1ALPHA; INTERLEUKIN 6; INTERLEUKIN 8; MEMBRANE PROTEIN;

ANIMAL CELL; ARTICLE; BIOLOGICAL MODEL; CELL MIGRATION; CHLAMYDIA TRACHOMATIS; CHRONIC INFLAMMATION; CONTROLLED STUDY; CYTOKINE RELEASE; ENZYME LINKED IMMUNOSORBENT ASSAY; GENETIC TRANSFECTION; HUMAN; HUMAN CELL; MICROSCOPY; NEUTROPHIL; NEUTROPHIL CHEMOTAXIS; NONHUMAN; PRIORITY JOURNAL; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; SEROLOGY; SEXUALLY TRANSMITTED DISEASE;

ANTI-BACTERIAL AGENTS; ANTIGENS, BACTERIAL; ANTIGENS, SURFACE; AZITHROMYCIN; BACTERIAL OUTER MEMBRANE PROTEINS; CELL LINE; CHEMOKINES; CHEMOTAXIS, LEUKOCYTE; CHLAMYDIA TRACHOMATIS; FEMALE; HUMANS; INTERLEUKIN-8; LIPOPOLYSACCHARIDES; NEUTROPHILS;

EID: 0032900971     PISSN: 00221899     EISSN: None     Source Type: Journal    
DOI: 10.1086/314676     Document Type: Article

References (45)

1. Stamm WE, Holmes KK. Chlamydia trachomatis infection of the adult. In: Holmes KK, Mardh PA, Sparling PF, Wiesner PJ, eds. Sexually transmitted diseases. 2nd ed. New York: McGraw-Hill, 1990:917-25.
2. Ridgway GL. Treatment of chlamydial genital infection. J Antimicrob Chemother 1997;40:311-4.
3. Patton DL, Sweeney YC, Bohannon NJ, et al. Effects of doxycycline and antiinflammatory agents on experimentally induced chlamydial upper genital tract infection in female macaques. J Infect Dis 1997;175:648-54.
4. Kiviat NB, Paavonen JA, Brockway J, et al. Cytologic manifestations of cervical and vaginal infections. I. Epithelial and inflammatory cellular changes. JAMA 1985;253:989-96.
5. Paavonen J, Kiviat NB, Brunham RC, et al. Prevalence and manifestations of endometritis among women with cervicitis. Am J Obstet Gynecol 1985;152:280-6.
6. Ho JL, He S, Hu A, et al. Neutrophils from human immunodeficiency virus (HIV) -seronegative donors induce HIV replication from HIV-infected patients' mononuclear cells and cell lines: an in vitro model of HIV transmission facilitated by Chlamydia trachomatis. J Exp Med 1995;181:1493-505.
7. Wyrick PB, Gerbig DG Jr, Knight ST, Raulston JE. Accelerated development of genital Chlamydia trachomatis serovar E in McCoy cells grown on microcarrier beads. Microb Pathog 1996;20:31-40.
8. Preparation of cells and materials for functional assays. In: Metcalf JA, Gallin JI, Nauseef WM, Root RK, eds. Laboratory manual of neutrophil function. London: Raven Press, 1986:2-4.
9. Panteix G, Guillaumond B, Harf R, et al. In vitro concentration of azithromycin in human phagocytic cells. J Antimicrob Chemother 1993;31(suppl E):1-4.
10. Raulston JE. Pharmacokinetics of azithromycin and erythromycin in human endometrial epithelial cells and in cells infected with Chlamydia trachomatis. J Antimicrob Chemother 1994;34:765-76.
11. Paul TR, Knight ST, Raulston JE, Wyrick PB. Delivery of azithromycin to Chlamydia trachomatis infected polarized human endometrial epithelial cells by polymorphonuclear leukocytes. J Antimicrob Chemother 1997;39:623-30.
12. Wyrick PB, Choong J, Knight ST, Goyeau D, Stuart ES, MacDonald AB. Chlamydia trachomatis antigens on the surface of infected human endometrial epithelial cells. Immunol Infect Dis 1994;4:131-41.
13. Raulston JE, Paul TR, Knight ST, Wyrick PB. Localization of Chlamydia trachomatis heat shock proteins 60 and 70 during infection of a human endometrial epithelial cell line in vitro. Infect Immun 1998;66:2323-9.
14. Darville T, Lafoon KK. Kishen LR, Rank RG. Tumor necrosis factor-alpha activity in genital tract secretions of guinea pigs infected with chlamydiae. Infect Immun 1995;63:4675-81.
15. Jung HC, Eckmann L, Yang SK., et al. A distinct array of proinflammatory cytokines is expressed in human colon epithelial cells in response to bacterial invasion. J Clin invest 1995;95:55-65.
16. Froyen G, Proost P, Ronsse I, et al. Cloning, bacterial expression and biological characterization of recombinant human granulocyte chemotactic protein-2 and differential expression of granulocyte chemotactic protein-2 and epithelial cell derived neutrophil activating peptide-78 mRNAs. Eur J Biochem 1997;243:762-9.
17. Haskill S, Peace A, Morris J, et al. Identification of three related human GRO genes encoding cytokine functions. Proc Nat Acad Sci USA 1990;87:7732-6.
18. Rovai LE, Herschman HR, Smith JB. Cloning and characterization of the human granulocyte chemotactic protein-2 gene. J Immunol 1997;158:5257-66.
19. Gladue RP, Bright GM, Isaacson RE, Newborg MF. In vitro and in vivo uptake of azithromycin (CP-62, 993) by phagocytic cells: possible mechanism of delivery and release at sites of infection. Antimicrob Agents Chemother 1989;33:277-82.
20. Frank MO, Sullivan GW, Carper HT, Mandell GL. In vitro demonstration of transport and delivery of antibiotics by polymorphonuclear leukocytes. Antimicrob Agents Chemother 1992;36:2584-8.
21. Morrison DC, Ryan JL. Endotoxins and disease mechanisms. Annu Rev Med 1987;38:417-32.
22. Raetz CRH. Biochemistry of endotoxins. Annu Rev Biochem 1990;59:129-70.
23. Richmond SJ, Sterling P. Localization of chlamydial group antigen in McCoy cell monolayers infected with Chlamydia trachomatis or Chlamydia psittaci. Infect Immun 1981;34:561-70.
24. Karimi S, Schloemer RJ, Wilde CE. Accumulation of lipopolysaccharide antigen in the plasma membranes of infected cells. Infect Immun 1989;57:1780-5.
25. Farina AR, Tiberio A, Tacconelli A, Cappabianca L, Gulino A, Mackay AR. Identification of plasminogen in MatrigelTM and its activation by reconstitution of this basement membrane extract. BioTechniques 1996;21:904-9.
26. Orkin RW, Gehron P, McGoodwin EB, Martin GR, Valantine T, Swarm R. A murine tumor producing a matrix of basement membrane. J Exp Med 1977;145:204-20.
27. Megran DW, Stiver HG, Bowie WR. Complement activation and stimulation of chemotaxis by Chlamydia trachomatis. Infect Immun 1985;49:670-3.
28. Hall RT, Strugnell T, Wu X, Devine DV, Stiver HG. Characterization of kinetics and target proteins for binding of human complement component C3 to the surface-exposed outer membrane of Chlamydia trachomatis serovar L2. Infect Immun 1993;61:1829-34.
29. Rasmussen SJ, Eckmann L, Quayle AJ, et al. Secretion of proinflammatory cytokines by epithelial cells in response to Chlamydia infection suggests a central role for epithelial cells in chlamydial pathogenesis. J Clin Invest 1997;99:77-87.
30. Barteneva N, Theodor I, Peterson EM, De La Maza LM. Role of neutrophils in controlling early stages of a Chlamydia trachomatis infection. Infect Immun 1996;64:4830-3.
31. Morrison RP, Feilzer K, Tumas DP. Gene knockout mice establish a primary protective role for major histocompatibility complex class II restricted responses in Chlamydia trachomatis genital tract infection. Infect Immun 1995;63:4661-8.
32. Darville T, Andrews CW Jr, Laffoon KK, Shymasami W, Kishen LR, Rank RG. Mouse strain -dependent variation in the course and outcome of chlamydial genital tract infection is associated with differences in host response. Infect Immun 1997;65:3065-73.
33. Darville T, Andrews CW Jr, Kishen LR, Rank RG, Williams DM. Transforming growth factor-beta is associated with increased pathology in gamma-interferon gene knockout mice infected with chlamydiae. In: Stephens RS, Byrne GI, Christiansen G, et al., eds. 9th International Symposium of Human Chlamydial Infections. Berkeley, CA: University of California Printing Services, 1998:407-10.
34. Ingalls RR, Rice PA, Qureshi N, Takayama K, Lin JS, Golenbock DT. Inflammatory cytokine response to Chlamydia trachomatis infection is endotoxin mediated. Infect Immun 1995;63:3125-30.
35. Wilde CE, Karimi S, Haak RA. Cell surface alterations during chlamydial infections. In: Leive L, Bonventre PF, eds. Microbiology - 1986. Washington, DC: American Society for Microbiology, 1986:96-8.
36. Ojcius DM, de Alba YB, Kanellopoulos JM, et al. Internalization of Chlamydia by dendritic cells and stimulation of Chlamydia-specific T cells. J Immunol 1998;160:1297-303.
37. Su H, Messer R, Whitmire W, et al. Vaccination against chlamydial genital tract infection after immunization with dendritic cells pulsed ex vivo with nonviable Chlamydia. J Exp Med 1998;188:809-18.
38. Dean D, Oudens E, Bolan G, Padian N, Schachter J. Major outer membrane protein variants of Chlamydia trachomatis are associated with severe upper genital tract infections and histopathology in San Francisco. J Infect Dis 1995;172:1013-22.
39. Scidmore-Carlson M, Shaw EI, Dooley CA, Hackstadt T. Identification and characterization of putative inclusion membrane proteins. In: Stephens RS, Byrne GI, Christiansen G, et al., eds. 9th International Symposium on Human Chlamydial Infections. Berkeley, CA: University of California Printing Services, 1998:103-6.
40. Hackstadt T, Fischer ER, Scidmore MA, Rocky DD, Heinzen RA. Origins and functions of the chlamydial inclusion. Trends Microbiol 1997;5:288-93.
41. Garcia-del Portillo F, Stein MA, Finlay BB. Release of lipopolysaccharide from intracellular compartments containing Salmonella typhimurium to vesicles of the host epithelial cell. Infect Immun 1997;65:24-34.
42. Beatty WL, Sansonetti PJ. Role of lipopolysaccharide in signaling to subepithelial polymorphonuclear leukocytes. Infect Immun 1997;65:4395-404.
43. Arici A, Seli E, Senturk LM, Gutierrez LS, Oral E, Taylor HS. Interleukin-8 in the human endometrium. J Clin Endocrinol Metab 1998;83:1783-7.
44. Rowell DL, Eckmann L, Dwinell MB, et al. Human hepatocytes express an array of proinflammatory cytokines after agonist stimulation or bacterial invasion. Am J Physiol 1997;273(2 Pt 1):G322-32.
45. Patton DL, Askienazy-Elbhar M, Henry-Suchet JH. Detection of Chlamydia trachomatis in fallopian tube tissue in women with post infectious tubal infertility. Am J Obstet Gynecol 1994;171:95-101.