Gene therapy for metastatic malignant melanoma: Evaluation of tolerance to intratumoral injection of cells producing recombinant retroviruses carrying the herpes simplex virus type 1 thymidine kinase gene, to be followed by ganciclovir administration

Human Gene Therapy

Volumn 7, Issue 2, 1996, Pages 255-267

  Klatzmann, David ^a   Herson, Serge ^a   Cherin, Patrick ^a   Chosidow, Olivier ^a   Baillet, François ^a   Bensimon, Gilbert ^a   Boyer, Olivier ^a   Salzmann, Jean Loup ^b  

^a PITIÉ SALPÊTRIÈRE HOSPITAL   (France)

^b AVICENNE HOSPITAL   (France)

Author keywords

[No Author keywords available]

Indexed keywords

GANCICLOVIR; THYMIDINE KINASE;

ANEMIA; ANTINEOPLASTIC ACTIVITY; ARTICLE; ATAXIA; ATTENTION DEFICIT DISORDER; BEHAVIOR DISORDER; CELL PROLIFERATION; CLINICAL PROTOCOL; COMA; DRUG SENSITIVITY; EOSINOPHILIA; FIBROBLAST; GASTROINTESTINAL SYMPTOM; GENE THERAPY; HALLUCINATION; HERPES SIMPLEX VIRUS 1; HUMAN; HYPERKINESIA; INTRAVENOUS DRUG ADMINISTRATION; MELANOMA; METASTASIS; NEUTROPENIA; PHASE 1 CLINICAL TRIAL; PHASE 2 CLINICAL TRIAL; RETROVIRUS; SEIZURE; TERATOGENESIS; THROMBOCYTOPENIA; TUMOR CELL DESTRUCTION; VERTIGO; VIRUS INFECTION; VIRUS RECOMBINANT;

ANIMALS; ANTIMETABOLITES; CLINICAL PROTOCOLS; CLINICAL TRIALS, PHASE I; CLINICAL TRIALS, PHASE II; FIBROBLASTS; GANCICLOVIR; GENE THERAPY; GENETIC VECTORS; HERPESVIRUS 1, HUMAN; HUMANS; MELANOMA; MICE; RETROVIRIDAE; THYMIDINE KINASE;

ANIMALIA; ATAXIA; HERPES; HUMAN HERPESVIRUS 1; MURINAE; UNIDENTIFIED RETROVIRUS;

EID: 0030047790     PISSN: 10430342     EISSN: None     Source Type: Journal    
DOI: 10.1089/hum.1996.7.2-255     Document Type: Article

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