Ethanol depression of cerebellar Purkinje neuron firing involves nicotinic acetylcholine receptors

Experimental Neurology

Volumn 143, Issue 2, 1997, Pages 319-322

  Freund, Ronald K ^a   Palmer, Michael R ^a  

^a UNIVERSITY OF COLORADO   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ALCOHOL; MECAMYLAMINE; NICOTINE; NICOTINIC RECEPTOR; NICOTINIC RECEPTOR BLOCKING AGENT;

ANESTHESIA; ANIMAL EXPERIMENT; ARTICLE; CEREBELLUM; CONTROLLED STUDY; ELECTROPHYSIOLOGY; MALE; NERVE CELL EXCITABILITY; NONHUMAN; PRIORITY JOURNAL; PURKINJE CELL; RAT;

EID: 0031080096     PISSN: 00144886     EISSN: None     Source Type: Journal    
DOI: 10.1006/exnr.1996.6371     Document Type: Article

References (17)

1. Blomqvist O., Soderpalm B., Engel J. A. Ethanol-induced locomotor activity: Involvement of central nicotinic acetylcholine receptors. Brain Res. Bull. 29:1992;173-178.
2. DiFranza J. R., Guerrara M. P. Alcoholism and smoking. J. Stud. Alcohol. 51:1990;130-135.
3. Eccles J. C., Ito M., Szentagothai J. The Cerebellum as a Neuronal Machine. 1967;Springer-Verlag, New York.
4. Freund R. K., van Horne C. G., Harlan T. H., Palmer M. R. Electrophysiological interactions of ethanol with GABAergic mechanisms in the rat cerebellum in vivo. Alcoholism: Clin. Exp. Res. 17:1993;321-327.
5. de la Garza R., Bickford-Wimer P. C., Freedman R., Hoffer B. J. Heterogeneity of nicotine actions in the rat cerebellum: An in vivo electrophysiologic study. J. Pharmacol. Exp. Ther. 240:1987;689-695.
6. de la Garza R., McGuire T. J., Freedman R., Hoffer B. J. Selective antagonism of nicotine actions in the rat cerebellum with α-bungarotoxin. Neuroscience. 23:1987;887-891.
7. de la Garza R., Freedman R., Hoffer B. J. Nicotine-induced inhibition of cerebellar Purkinje neurons: Specific actions of nicotine and selective blockade by mecamylamine. Neuropharmacology. 28:1989;495-501.
8. Gauvin D. V., Moore K. R., Holloway F. A. Do rat strain differences in ethanol consumption reflect differences in ethanol sensitivity or the preparedness to learn? Alcohol. 10:1993;37-43.
9. Henningfield J. E., Chait L. D., Griffiths R. R. Cigarette smoking and subjective response in alcoholics: Effects of pentobarbital. Clin. Pharmacol. Ther. 31:1983;806-812.
10. Lin A. M.-Y., Freund R. K., Palmer M. R. Ethanol potentiation of GABA-induced electrophysiological responses in cerebellum: Requirement for catecholamine modulation. Neurosci. Lett. 122:1991;154-158.
11. Lin A. M.-Y., Freund R. K., Palmer M. R. Sensitization of gamma-aminobutyric acid-induced depressions of cerebellar Purkinje neurons to the potentiative effects of ethanol by beta adrenergic mechanisms in rat brain. J. Pharmacol. Exp. Ther. 265:1993;426-432.
12. Lin A. M-Y., Freund R. K., Hoffer B. J., Palmer M. R. Ethanol-induced depressions of cerebellar Purkinje neurons are potentiated by β-adrenergic mechanisms in rat brain. J. Pharmacol. Exp. Ther. 271:1994;1175-1180.
13. Palmer M. P. Micro pressure-ejection: A complementary technique to microiontophoresis for neuropharmacological studies in the mammalian central nervous system. J. Electrophysiol. Tech. 9:1982;123-139.
14. Palmer M. R., Hoffer B. J. Catecholamine modulation of enkephalin-induced electrophysiological responses in cerebral cortex. J. Pharmacol. Exp. Ther. 213:1980;205-215.
15. Palmer M. R., van Horne C. G., Harlan J. T., Moore E. A. Antagonism of ethanol effects on cerebellar Purkinje neurons by the benzodiazepine in verse agonists Ro 15-4513 and FG 7142: Electrophysiological studies. J. Pharmacol. Exp. Ther. 247:1988;1018-1024.
16. A. Nature (London). 328:1987;221-227.
17. Wize R. A., Bozarth M. A. A psychomotor stimulant theory of addiction. Psychol. Rev. 94:1987;469-492.