Differential modulation of rat neuronal nicotinic receptor subtypes by acute application of ethanol

British Journal of Pharmacology

Volumn 122, Issue 8, 1997, Pages 1661-1668

  Covernton, Patrick J O ^a   Connolly, John G ^a  

^a UNIVERSITY OF STRATHCLYDE   (United Kingdom)

Author keywords

Addiction; Ethanol; Ion channels; Neuronal; Nicotinic receptors; Oocytes; Plasticity; Smoking

Indexed keywords

ALCOHOL; NICOTINIC AGENT; NICOTINIC RECEPTOR; RECEPTOR SUBTYPE; RECEPTOR SUBUNIT;

ANIMAL CELL; ARTICLE; CONTROLLED STUDY; NONHUMAN; OOCYTE; PRIORITY JOURNAL; VOLTAGE CLAMP; XENOPUS;

ANIMALS; CENTRAL NERVOUS SYSTEM DEPRESSANTS; ETHANOL; NEURONS; RATS; RECEPTORS, NICOTINIC; XENOPUS;

EID: 0031449304     PISSN: 00071188     EISSN: None     Source Type: Journal    
DOI: 10.1038/sj.bjp.0701568     Document Type: Article

References (42)

1. ABADJI, V., RAINES, D.E., DALTON, L.A. & MILLER, K.W. (1994). Lipid-protein interactions and protein dynamics in vesicles containing the nicotinic acetylcholine receptor: a study with ethanol. Biochim. Biophys. Acta, 1194, 25-34.
2. ARCAVA, Y., FROES-FERRAO, M.M., PEREIRA, E.F.R. & ALBUQUERQUE, E.X. (1991). Sensitivity of N-Methyl-D-Aspartate (NMDA) and nicotinic acetylcholine receptors to ethanol and pyrazole. Ann. New York Acad. Sci., 625, 451-472.
3. BERTRAND, D., BERTRAND, S. & BALLIVET, M. (1992). Pharmacological properties of the homomeric α7 receptor. Neurosci. Lett., 146, 87-90.
4. BLOMQVIST, O., ENGEL, J.A., NISSBRANDT, H & SODERPALM, B. (1993). The mesolimbic dopamine-activating properties of ethanol are antagonized by mecamylamine. Eur. J. Pharmacol., 249, 207-213.
5. BLOMQVIST, O., ERICSON, M., JOHNSON, D.H., ENGEL, J.A. & SODERPALM, B. (1996). Voluntary ethanol intake in the rat: effects of nicotinic acetylcholine receptor blockade or subchroic nicotine treatment. Eur. J. Pharmacol., 314, 257-267.
6. BOULTER, J., CONNOLLY, J., DENERIS, E., GOLDMAN, D., HEINEMANN, S. & PATRICK, J. (1987). Functional expression of two neuronal nicotinic acetlcholine receptors from cDNA clones identifies a gene family. Proc. Natl. Acad. Sci. U.S.A., 84, 7763-7767.
7. BOULTER, J., O'SHEA-GREENFIELD, A., DUVOISIN, R.M., CONNOLLY, J.G., WADA, E., JENSEN, A., BALLIVET, M., DENERIS, E.S., HEINEMANN, S. & PATRICK, J. (1990). α3, α5 and β4, three members of a rat neuronal nicotinic acetylcholine receptor related gene family form a gene cluster. J. Biol. Chem., 265, 4472-4482.
8. CONNOLLY, J.G., GIBB, A.J. & COLQUHOUN, D. (1995). Multiple subtypes of large conductance neuronal nicotinic acetylcholine receptors studied in thin slices of rat medial habenula. J. Physiol., 484, 87-105.
9. COUTURIER, S., BERTRAND, D., MATTER, J.-M., HERNANDEZ, M.-C., BERTRAND, S., MILLAR, N., VALERA, S., BARKAS, T. & BALLIVET, M. (1990). A neuronal nicotinic acetylcholine receptor subunit (α7) is developmentally regulated and forms a homo-oligomeric channel blocked by α-Btx. Neuron, 5, 847-856.
10. COVERNTON, P.J.O. & CONNOLLY, J.G. (1995). Ethanol can both inhibit and potentiate neuronal nicotinic AChRs. Br. J. Pharmacol. Proc: Suppl., 116, 450P.
11. COVERNTON, P.J.O. & CONNOLLY, J.G. (1997). Differential modulation of the α4 1β2 and α7 neuronal nicotinic receptor subtypes by ethanol. Br. J. Pharmacol. Proc. Suppl., 120, 274P.
12. COVERNTON, P.J.O., DUVOISIN, R. & CONNOLLY, J.G. (1995). Modulation of the activity of the nicotinic α3β4 receptor subtype by alcohol. Soc: Neurosci. Abst., 21, 528.13.
13. CRISWELL, H.E., SIMSON, P.E., DUNCAN, G.E., McCOWN, T.J., HERBERT, J.S., MORROW, A.L. & BREESE, G.L. (1993). Molecular basis for regionally specific action of ethanol on gamma-amino butyric acid (A) receptors: Generalisation to other ligand-gated ion channels. J. Pharmacol. Exp. Ther., 267, 552-537.
14. DAR, M.S., LI, C. & BOWMAN, E.R. (1993). Central interactions between ethanol, (-)-nicotine and (-)-cotinine in mice. Brain Res. Bull., 32, 23-28.
15. DE FIEBRE, C.M. & COLLINS, A.C. (1992). Classical genetic analyses of responses to nicotine and ethanol in crosses from long- and short-term sleep mice. J. Pharmacol. Exp. Ther., 261, 173-180.
16. DE FIEBRE, C.M., PAPKE, R.L. & MEYER, E.M. (1995). Effects of ethanol on neuronal nicotinic receptors expressed in Xenopus oocytes. Soc: Neurosci. Abst., 21, p499, Abs. 206.8.
17. 2+ and protein kinase C. J. Neurosci., 15, 3162-3171.
18. DINELY-MILLER, K. & PATRICK, J. (1992). Gene transcripts for the nicotinic acetyleholine receptor subunit beta4 are distributed in multiple areas of the rat central nervous system. Mol. Brain Res., 16, 339-344.
19. DUVOISIN, R.M., DENERIS, E.S., PATRICK, J. & HEINEMANN, S.E. (1989). The functional diversity of neuronal nicotinic acetylcholine receptors is increased by a novel subunit β4. Neuron, 3, 589-596.
20. FRANKS, N. P. & LIEB, W.R. (1994). Molecular and cellular mechanisms of general anaesthesia. Nature, 367, 608-613.
21. FLORES, C.M., DECAMP, R.M., KILO, R.M., ROGERS, S.W. & HARGREAVES, K.M. (1996). Neuronal nicotinic receptor expression in sensory neurons of the rat trigeminal ganglion: Demonstration of α3β4, a novel subtype in the mammalian nervous system. J. Neurosci., 16, 7892-7901.
22. FRÖLICH, R., PATZELT, R. & ILLES, P. (1994). Inhibition by ethanol of excitatory amino acid receptors and nicotinic acetylcholine receptors in rat locus coeruleus neurons. Naunyn-Schmiedeberg's Arch. Pharmacol., 350, 626-631.
23. GURANTZ, D., HAROOTUNIAN, A.T., TSIEN, R.Y., DIONNE, V.E. & MARGIOTTA, J.F. (1994). VIP modulates neuronal nicotinic acelylcholine receptor function by a cyclic AMP-dependent mechanism. J. Neurosci., 14, 3540-3547.
24. KUZLOWSKI, L.T., HENNINGFIELD, J.E., KEENAN, R.M., LEI, H., LEIGH, G., JELINEK, L.C., POPE, M.A. & HAERTZEN, C.A. (1993). Patterns of alcohol, cigarette, and caffeine and other drug use in two drug abusing populations. J. Subst. Abuse Treat., 10, 171-179.
25. LI, C., AGUAYO, L., PEOPLPS, R. & WEIGHT, F.F. (1993). Ethanol inhibits a neuronal ATP-gated ion channel. Mol. Pharmacol., 44, 871-875.
26. + channel determined by construction of multimeric cDNAs. Neuron, 9, 861-871.
27. A receptor whole cell currents expressed in L929 fibroblasts. Neuron, 13, 1421-1431.
28. MULLE, C., CHOQUET, D., KORN, H. & CHANGEUX, J.-P. (1992). Calcium influx through nicotinic receptor in rat central neurons: Its relevance to cellular regulation. Neuron, 8, 135-143.
29. NAGATA, K., AISTRUP, G.L., HUANG, C.-S., MARSZALEC, W., SONG, J.-H., YEH, J.Z. & NARAHASHI, T. (1996). Potent modulation of neuronal nicotinic acetylcholine receptor channel by ethanol. Neurosci. Lett., 217, 189-193.
30. OGDEN, D.C. & COLQUHOUN, D. (1985). Ion channel block by acetylcholine, carbachol and suberyldicholine at the frog neuromuscular junction. Proc. R. Soc. Lond. B., 225, 329-355.
31. PAI, J.K., EGAN, M.I. & BILLAH, M.M. (1988). Activation of phosholipase D by chemotactic peptide in HL-60 granulocytes. Biochem. Biophys. Res. Commun., 150, 355-364.
32. PAPKE, R.L. & HEINEMANN, S.F. (1991). The role of the β4 subunit in determining the kinetic properties of rat neuronal nicotinic α3-receptors. J. Physiol., 440, 95-112.
33. SAMSON, H. & HARRIS, R. (1992). Neurobiology of alcohol abuse. Trends Pharmacol. Sci., 13, 206-211.
34. SEGUELA, P., WADICHE, K., DINELEY-MILLER, K., DANI, J.A. & PATRICK, J.W. (1993). Molecular cloning, functional properties, and distribution of rat brain α7: a nicotinic cation channel highly permeable to calcium. J. Neurosci., 13, 596-604.
35. VALLENTA, D.C.C., DOWNING, J.E. & ROLE, L.W. (1993). Peptide modulation of acetylcholine receptor modulation controlling transmitter release from sympathetic neurons in vitro. J. Neurophysiol., 69, 928-942.
36. 2+ permeability of neuronal nicotinic acetylcholine receptors, Neuron, 8, 127-134.
37. VERNINO, S., ROGERS, M., RADCLIFF, K.A. & DANI, J. (1994). Quantitative measurement of calcium flux through muscle and neuronal nicotinic acetylcholine receptors. J. Neurosci., 14, 5514-5524.
38. A receptor expressed in xenopus oocytes requires 8 amino acids contained in the γ2L subunit. Neuron, 1, 27-33.
39. A receptors requires phosphorylation of the alternatively spliced variant of the γ2 subunit. FEBS Letts., 313, 113-117.
40. A-mediated synaptic current by ethanol in Hippocampal CA1 neurons: possible role of protein kinase C. J. Pharmacol. Exp. Ther., 268, 1388-1395.
41. YU, D., ZHANG, L., EISELÉ, J.-L., BERTRAND, D., CHANGEUX, J.-P. & WEIGHT, F.F. (1996). Ethanol inhibition of nicotinic acetylcholine type α7 receptors involves the amino-terminal domain of the receptor. Mol. Pharmacol., 50, 1010-1016.
42. YU, X.-M., ASKALAN, R., KEIL H, G.J. & SALTER, M.W. (1997). NMDA channel regulation by channel-associated protein tyrosine kinase Src. Science, 275, 674-678.