-
1
-
-
0030626451
-
Optimizing industrial enzymes by directed evolution
-
Arnold, F.H., and Moore, J.C. 1997. Optimizing industrial enzymes by directed evolution. Adv. Biochem. Eng. Biotechnol. 58, 1-14.
-
(1997)
Adv. Biochem. Eng. Biotechnol.
, vol.58
, pp. 1-14
-
-
Arnold, F.H.1
Moore, J.C.2
-
2
-
-
0026328675
-
Genomic mapping by anchoring random clones: A mathematical analysis
-
Arratia, R., Lander, E.S., Tavare, S., and Waterman, M.S. 1991. Genomic mapping by anchoring random clones: a mathematical analysis. Genomics 11, 806-827.
-
(1991)
Genomics
, vol.11
, pp. 806-827
-
-
Arratia, R.1
Lander, E.S.2
Tavare, S.3
Waterman, M.S.4
-
3
-
-
0024308334
-
Fine structure genetic mapping of human chromosomes using the polymerase chain reaction on single sperm: Experimental design considerations
-
Boehnke, M., Arnheim, N., Li, H., and Collins, F.S. 1989. Fine structure genetic mapping of human chromosomes using the polymerase chain reaction on single sperm: experimental design considerations. Am. J. Hum. Genet. 45, 21-32.
-
(1989)
Am. J. Hum. Genet.
, vol.45
, pp. 21-32
-
-
Boehnke, M.1
Arnheim, N.2
Li, H.3
Collins, F.S.4
-
4
-
-
0026321407
-
Statistical methods for multipoint radiation hybrid mapping
-
Boehnke, M., Lange, K., and Cox, D. 1991. Statistical methods for multipoint radiation hybrid mapping. Am. J. Hum. Genet. 49, 1174-1188.
-
(1991)
Am. J. Hum. Genet.
, vol.49
, pp. 1174-1188
-
-
Boehnke, M.1
Lange, K.2
Cox, D.3
-
5
-
-
0016000938
-
Analysis of repeating DNA sequences by reassociation
-
Britten, R.J., Graham, D.E., and Neufeld, B.R. 1974. Analysis of repeating DNA sequences by reassociation. Methods Enzymol. 29, 363-418.
-
(1974)
Methods Enzymol.
, vol.29
, pp. 363-418
-
-
Britten, R.J.1
Graham, D.E.2
Neufeld, B.R.3
-
6
-
-
85045502002
-
Randomization of genes by PCR mutagenesis
-
Cadwell, R.C., and Joyce, G.F. 1992. Randomization of genes by PCR mutagenesis. P.C.R. Method Appl. 2, 28-33.
-
(1992)
P.C.R. Method Appl.
, vol.2
, pp. 28-33
-
-
Cadwell, R.C.1
Joyce, G.F.2
-
7
-
-
0025131820
-
A somatic cell genetic method for constructing high-resolution maps of mammalian chromosomes
-
Cox, D.R., Burmeister, M., Price, E.R., Kim, S., and Myers, R.M. 1990. A somatic cell genetic method for constructing high-resolution maps of mammalian chromosomes. Science 250, 245-250.
-
(1990)
Science
, vol.250
, pp. 245-250
-
-
Cox, D.R.1
Burmeister, M.2
Price, E.R.3
Kim, S.4
Myers, R.M.5
-
8
-
-
0032518266
-
DNA shuffling of a family of genes from diverse species accelerates directed evolution
-
Crameri, A., Raillard, S., Bermudez, E., and Stemmer, W.P.C. 1998. DNA shuffling of a family of genes from diverse species accelerates directed evolution. Nature 391, 288-291.
-
(1998)
Nature
, vol.391
, pp. 288-291
-
-
Crameri, A.1
Raillard, S.2
Bermudez, E.3
Stemmer, W.P.C.4
-
10
-
-
0028869690
-
Diversity of oligonucleotide functions
-
Gold, L., Polisky, B., Uhlenbeck, O., and Yarus, M. 1995. Diversity of oligonucleotide functions. Annu. Rev. Biochem. 64, 763-797.
-
(1995)
Annu. Rev. Biochem.
, vol.64
, pp. 763-797
-
-
Gold, L.1
Polisky, B.2
Uhlenbeck, O.3
Yarus, M.4
-
11
-
-
0026325728
-
SELEXION: Systematic evolution of ligands by exponential enrichment with integrated optimization by non-linear analysis
-
Irvine, D., Tuerk, C., and Gold, L. 1991. SELEXION: systematic evolution of ligands by exponential enrichment with integrated optimization by non-linear analysis. J. Mol. Biol. 222, 739-761.
-
(1991)
J. Mol. Biol.
, vol.222
, pp. 739-761
-
-
Irvine, D.1
Tuerk, C.2
Gold, L.3
-
12
-
-
0031543435
-
Directed evolution of enzyme catalysts
-
Kuchner, O., and Arnold, F.H. 1997. Directed evolution of enzyme catalysts. Trends Biotechnol. 15, 483-531.
-
(1997)
Trends Biotechnol.
, vol.15
, pp. 483-531
-
-
Kuchner, O.1
Arnold, F.H.2
-
13
-
-
0023988195
-
Genomic mapping by fingerprinting random clones: A mathematical analysis
-
Lander, E.S., and Waterman, M.S. 1988. Genomic mapping by fingerprinting random clones: a mathematical analysis. Genomics 2, 231-239.
-
(1988)
Genomics
, vol.2
, pp. 231-239
-
-
Lander, E.S.1
Waterman, M.S.2
-
15
-
-
0002694056
-
A method for random mutagenesis of a defined DNA segment using a modified polymerase chain reaction
-
Leung, D.W., Chen, F., and Goeddel, D.V. 1989. A method for random mutagenesis of a defined DNA segment using a modified polymerase chain reaction. Technique 1, 11-15.
-
(1989)
Technique
, vol.1
, pp. 11-15
-
-
Leung, D.W.1
Chen, F.2
Goeddel, D.V.3
-
16
-
-
0031587291
-
Strategies for the in vitro evolution of protein function: Enzyme evolution by random recombination of improved sequences
-
Moore, C.M., Jin, H.M., Kuchner, O., and Arnold, F.H. 1997. Strategies for the in vitro evolution of protein function: enzyme evolution by random recombination of improved sequences. J. Mol. Biol. 272, 336-347.
-
(1997)
J. Mol. Biol.
, vol.272
, pp. 336-347
-
-
Moore, C.M.1
Jin, H.M.2
Kuchner, O.3
Arnold, F.H.4
-
17
-
-
0030722164
-
Applications of DNA shuffling to pharmaceuticals and vaccines
-
Patten, P.A., Howard, B.J., and Stemmer, W.P.C. 1997. Applications of DNA shuffling to pharmaceuticals and vaccines. Curr. Opin. Biotechnol. 8, 724-733.
-
(1997)
Curr. Opin. Biotechnol.
, vol.8
, pp. 724-733
-
-
Patten, P.A.1
Howard, B.J.2
Stemmer, W.P.C.3
-
18
-
-
0023949179
-
Combinatorial cassette mutagenesis as a probe of the informational content of protein sequences
-
Reidhaar-Olson, J.F., and Sauer, R.T. 1988. Combinatorial cassette mutagenesis as a probe of the informational content of protein sequences. Science 241, 53-57.
-
(1988)
Science
, vol.241
, pp. 53-57
-
-
Reidhaar-Olson, J.F.1
Sauer, R.T.2
-
19
-
-
0027485082
-
Ordered restriction maps of Saccharomyces cerevisiae chromosomes constructed by optical mapping
-
Schwartz, D., Li, X., Hernandez, L., Ramnarain, S., Huff, E., and Wang, Y. 1993. Ordered restriction maps of Saccharomyces cerevisiae chromosomes constructed by optical mapping. Science 262, 110-114.
-
(1993)
Science
, vol.262
, pp. 110-114
-
-
Schwartz, D.1
Li, X.2
Hernandez, L.3
Ramnarain, S.4
Huff, E.5
Wang, Y.6
-
20
-
-
0030220851
-
Engineering new functions and altering existing functions
-
Shao, Z., and Arnold, F.H. 1996. Engineering new functions and altering existing functions. Curr. Opin. Struct. Biol. 6, 513-518.
-
(1996)
Curr. Opin. Struct. Biol.
, vol.6
, pp. 513-518
-
-
Shao, Z.1
Arnold, F.H.2
-
21
-
-
0032518181
-
Random-priming in vitro recombination: An effective tool for directed evolution
-
Shao, Z., Zhao, H., Giver, L., and Arnold, F.H. 1998. Random-priming in vitro recombination: an effective tool for directed evolution Nucleic Acids Res. 26, 681-683.
-
(1998)
Nucleic Acids Res.
, vol.26
, pp. 681-683
-
-
Shao, Z.1
Zhao, H.2
Giver, L.3
Arnold, F.H.4
-
22
-
-
0028088274
-
The progeny of sexual PCR
-
Smith, G.P. 1994. The progeny of sexual PCR. Nature 370, 424-325.
-
(1994)
Nature
, vol.370
, pp. 424-1325
-
-
Smith, G.P.1
-
23
-
-
0028110130
-
DNA shuffling by random fragmentation and reassembly: In vitro recombination for molecular evolution
-
Stemmer, W.P.C. 1994a. DNA shuffling by random fragmentation and reassembly: in vitro recombination for molecular evolution. Proc. Natl. Acad. Sci. U.S.A. 91, 10747-10751.
-
(1994)
Proc. Natl. Acad. Sci. U.S.A.
, vol.91
, pp. 10747-10751
-
-
Stemmer, W.P.C.1
-
24
-
-
0028050350
-
Rapid evolution of a protein in vitro by DNA shuffling
-
Stemmer, W.P.C. 1994b. Rapid evolution of a protein in vitro by DNA shuffling. Nature 370, 389-391.
-
(1994)
Nature
, vol.370
, pp. 389-391
-
-
Stemmer, W.P.C.1
-
25
-
-
0029868473
-
A mathematical analysis of in vitro molecular selection-amplification
-
Sun, F., Galas, D., and Waterman, M.S. 1996. A mathematical analysis of in vitro molecular selection-amplification. J. Mol. Biol. 258, 650-660.
-
(1996)
J. Mol. Biol.
, vol.258
, pp. 650-660
-
-
Sun, F.1
Galas, D.2
Waterman, M.S.3
-
26
-
-
0342316541
-
Searching sequence space
-
Stemmer, W.P.C. 1995. Searching sequence space. Biotechnology 13, 549-553.
-
(1995)
Biotechnology
, vol.13
, pp. 549-553
-
-
Stemmer, W.P.C.1
-
28
-
-
0014413352
-
Kinetics of renaturation of DNA
-
Wetmur, J.G., and Davidson, N. 1968. Kinetics of renaturation of DNA. J. Mol. Biol. 31, 349-370.
-
(1968)
J. Mol. Biol.
, vol.31
, pp. 349-370
-
-
Wetmur, J.G.1
Davidson, N.2
-
29
-
-
0030989062
-
Directed evolution of a fucosidase from a galactosidase by DNA shuffling and screening
-
Zhang, J.H., Dawes, G., and Stemmer, W.P.C. 1997. Directed evolution of a fucosidase from a galactosidase by DNA shuffling and screening. Proc. Natl. Acad. Sci. U.S.A. 94, 4504-4509.
-
(1997)
Proc. Natl. Acad. Sci. U.S.A.
, vol.94
, pp. 4504-4509
-
-
Zhang, J.H.1
Dawes, G.2
Stemmer, W.P.C.3
-
30
-
-
0030858562
-
Functional and nonfunctional mutations distinguished by random recombination of homologous genes
-
Zhao, H., and Arnold, F.H. 1997. Functional and nonfunctional mutations distinguished by random recombination of homologous genes. Proc. Natl. Acad. Sci. U.S.A. 94, 7997-8000.
-
(1997)
Proc. Natl. Acad. Sci. U.S.A.
, vol.94
, pp. 7997-8000
-
-
Zhao, H.1
Arnold, F.H.2
-
31
-
-
0031909113
-
Molecular evolution by staggered extension process (StEP) in vitro recombination
-
Zhao, H., Giver, L., Shao, Z., Affholter, J.A., and Arnold, F.H. 1998. Molecular evolution by staggered extension process (StEP) in vitro recombination. Nat. Biotechnol. 16, 258-261.
-
(1998)
Nat. Biotechnol.
, vol.16
, pp. 258-261
-
-
Zhao, H.1
Giver, L.2
Shao, Z.3
Affholter, J.A.4
Arnold, F.H.5
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