Stable one-step technetium-99m labeling of His-tagged recombinant proteins with a novel Tc(I)-carbonyl complex

Nature Biotechnology

Volumn 17, Issue 9, 1999, Pages 897-901

  Waibel, Robert ^a   Alberto, Roger ^a   Willuda, Jörg ^b   Finnern, Ricarda ^c   Schibli, Roger ^a   Stichelberger, Albert ^a   Egli, André ^a   Abram, Ulrich ^d   Mach, Jean Pierre ^c   Plückthun, Andreas ^b   Schubiger, P August ^a  

^a PAUL SCHERRER INSTITUTE   (Switzerland)

^b UNIVERSITY OF ZURICH   (Switzerland)

^c UNIVERSITY OF LAUSANNE   (Switzerland)

^d INSTITUTE OF ION BEAM PHYSICS AND MATERIALS RESEARCH   (Germany)

Author keywords

Imaging; Organometallic technetium; Radiolabeling; Recombinant proteins; Targeting

Indexed keywords

CARBONYL DERIVATIVE; RECOMBINANT PROTEIN; TECHNETIUM 99M;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANTIBODY LABELING; ARTICLE; DIAGNOSTIC IMAGING; DRUG DISTRIBUTION; ISOTOPE LABELING; MOUSE; NONHUMAN; ORGANIC CHEMISTRY; PRIORITY JOURNAL; TUMOR LOCALIZATION;

ALDEHYDES; ANIMALS; ANTIBODIES; CA-15-3 ANTIGEN; CHROMATOGRAPHY, AFFINITY; HISTIDINE; HUMANS; IMMUNOGLOBULIN FRAGMENTS; ISOTOPE LABELING; KETONES; MICE; MICE, NUDE; ORGANOTECHNETIUM COMPOUNDS; RADIOPHARMACEUTICALS; RECOMBINANT PROTEINS; TECHNETIUM; TISSUE DISTRIBUTION;

ANIMALIA;

EID: 0032884409     PISSN: 10870156     EISSN: None     Source Type: Journal    
DOI: 10.1038/12890     Document Type: Article

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