Resiniferatoxin-type phorboid vanilloids display capsaicin-like selectivity at native vanilloid receptors on rat DRG neurons and at the cloned vanilloid receptor VR1

British Journal of Pharmacology

Volumn 128, Issue 2, 1999, Pages 428-434

  Szallasi, A ^a,d   Szabo T ^a   Biro T ^a   Modarres, S ^a   Blumberg, P M ^a   Krause, J E ^b   Cortright, D N ^b   Appendino, G ^c  

^a NATIONAL CANCER INSTITUTE   (United States)

^b NEUROGEN CORPORATION   (United States)

^c UNIVERSITY OF TURIN   (Italy)

^d SAINT LOUIS UNIVERSITY SCHOOL OF MEDICINE   (United States)

Author keywords

3H resiniferatoxin binding capsaicin; Capsaicin type vanilloid pharmacology; Native vanilloid receptors; Phorboid vanilloids; Phorbol 12,13 didecanoate 20 homovanillate; Vanilloid receptor subtype 1 (VR1); VR1 transfected CHO cells

Indexed keywords

CALCIUM ION; CAPSAICIN; CAPSAZEPINE; HOMOVANILLIC ACID; PHORBOL 12,13 DIDECANOATE 20 HOMOVANILLATE; PHORBOL DIDECANOATE; RESINIFERATOXIN; UNCLASSIFIED DRUG; VANILLOID RECEPTOR;

ANIMAL CELL; ARTICLE; CALCIUM MOBILIZATION; CALCIUM TRANSPORT; CHO CELL; CONTROLLED STUDY; DRUG POTENCY; DRUG RECEPTOR BINDING; FEMALE; GENETIC TRANSFECTION; MOLECULAR CLONING; NERVE CELL CULTURE; NERVE MEMBRANE; NONHUMAN; PRIORITY JOURNAL; RAT; SPINAL GANGLION; STRUCTURE ACTIVITY RELATION;

ANIMALS; CALCIUM; CAPSAICIN; CELL MEMBRANE; CHO CELLS; CLONING, MOLECULAR; CRICETINAE; DITERPENES; DNA, COMPLEMENTARY; FEMALE; FLUORESCENT DYES; GANGLIA, SPINAL; NEUROTOXINS; RATS; RATS, SPRAGUE-DAWLEY; RECEPTORS, DRUG;

EID: 0032881344     PISSN: 00071188     EISSN: None     Source Type: Journal    
DOI: 10.1038/sj.bjp.0702810     Document Type: Article

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