Synthesis and evaluation of phorboid 20-homovanillates: Discovery of a class of ligands binding to the vanilloid (capsaicin) receptor with different degrees of cooperativity

Journal of Medicinal Chemistry

Volumn 39, Issue 16, 1996, Pages 3123-3131

  Appendino, Giovanni ^a   Cravotto, Giancarlo ^a   Palmisano, Giovanni ^a   Annunziata, Rita ^b   Szallasi, Arpad ^c  

^a UNIVERSITY OF TURIN   (Italy)

^b Dipartimento di Chimica Organica e Industriale   (Italy)

^c KAROLINSKA INSTITUTE   (Sweden)

Author keywords

[No Author keywords available]

Indexed keywords

CAPSAICIN; HOMOVANILLIC ACID; PHORBOL 12 ACETATE 13 MYRISTATE; PHORBOL ESTER; RESINIFERATOXIN; VANILLOID RECEPTOR;

ANIMAL TISSUE; ANTINOCICEPTION; ARTICLE; BINDING AFFINITY; COMPETITIVE INHIBITION; DRUG SCREENING; DRUG SYNTHESIS; HYPOTHERMIA; LIGAND BINDING; NONHUMAN; PROTEIN PROTEIN INTERACTION; RAT;

ANIMALS; BODY TEMPERATURE; DITERPENES; EDEMA; HOMOVANILLIC ACID; MAGNETIC RESONANCE SPECTROSCOPY; MASS SPECTROMETRY; MEMBRANE PROTEINS; MOLECULAR STRUCTURE; PHORBOL ESTERS; PROTEIN BINDING; RATS; RECEPTORS, DRUG; SPINAL CORD;

EID: 0029740667     PISSN: 00222623     EISSN: None     Source Type: Journal    
DOI: 10.1021/jm960063l     Document Type: Article

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