메뉴 건너뛰기




Volumn 37, Issue 3, 1999, Pages 171-180

Mechanisms underlying the anti-epileptic efficacy of the ketogenic diet

Author keywords

Animal models; Energy metabolism; Hormones; Neuronal excitability; Neurotransmitters; pH

Indexed keywords

HORMONE; NEUROTRANSMITTER;

EID: 0032878960     PISSN: 09201211     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0920-1211(99)00069-8     Document Type: Conference Paper
Times cited : (114)

References (43)
  • 2
    • 0029435463 scopus 로고
    • Effects of unbalanced diets on cerebral glucose metabolism in the adult rat
    • Al-Mudallal A.S., Levin B.E., Lust W.D., Harik S.I. Effects of unbalanced diets on cerebral glucose metabolism in the adult rat. Neurology. 45:1995;2261-2265.
    • (1995) Neurology , vol.45 , pp. 2261-2265
    • Al-Mudallal, A.S.1    Levin, B.E.2    Lust, W.D.3    Harik, S.I.4
  • 3
    • 0016332555 scopus 로고
    • An animal model for the ketogenic diet
    • Appleton D.B., DeVivo D.C. An animal model for the ketogenic diet. Epilepsia. 15:1974;211-227.
    • (1974) Epilepsia , vol.15 , pp. 211-227
    • Appleton, D.B.1    DeVivo, D.C.2
  • 4
    • 0028023852 scopus 로고
    • Ictal patterns of cerebral glucose utilization in children with epilepsy
    • Chugani H.T., Rintahaka P.J., Shewmon D.A. Ictal patterns of cerebral glucose utilization in children with epilepsy. Epilepsia. 35:1994;813-822.
    • (1994) Epilepsia , vol.35 , pp. 813-822
    • Chugani, H.T.1    Rintahaka, P.J.2    Shewmon, D.A.3
  • 5
    • 0029985632 scopus 로고    scopus 로고
    • + pump in skeletal muscle: Quantification, regulation and functional significance
    • + pump in skeletal muscle: quantification, regulation and functional significance. Acta Physiol. Scand. 156:1996;227-235.
    • (1996) Acta Physiol. Scand. , vol.156 , pp. 227-235
    • Clausen, T.1
  • 7
    • 0027311861 scopus 로고
    • The expanding clinical spectrum of mitochondrial diseases
    • DeVivo D.C. The expanding clinical spectrum of mitochondrial diseases. Brain Dev. 15:1993;1-22.
    • (1993) Brain Dev. , vol.15 , pp. 1-22
    • DeVivo, D.C.1
  • 9
    • 0029833561 scopus 로고    scopus 로고
    • Regulation of GABA level in rat brain synaptosomes: Fluxes through enzymes of the GABA shunt and effects of glutamate, calcium, and ketone bodies
    • Ereci'nska M., Nelson D., Daikhin Y., Yudhoff M. Regulation of GABA level in rat brain synaptosomes: fluxes through enzymes of the GABA shunt and effects of glutamate, calcium, and ketone bodies. J. Neurochem. 67:1996;2325-2334.
    • (1996) J. Neurochem. , vol.67 , pp. 2325-2334
    • Ereci'nska, M.1    Nelson, D.2    Daikhin, Y.3    Yudhoff, M.4
  • 10
    • 0032856461 scopus 로고    scopus 로고
    • Endocrine regulation of neurotransmitter transporters
    • Figlewicz D.P. Endocrine regulation of neurotransmitter transporters. Epilepsy Res. 37:1999;203-210.
    • (1999) Epilepsy Res. , vol.37 , pp. 203-210
    • Figlewicz, D.P.1
  • 11
    • 0003363242 scopus 로고    scopus 로고
    • Beta-hydroxybutyrate potentiates GABA-A-mediated inhibitory postsynaptic potentials in immature hippocampal CA1 neurons
    • Ge S., Niesen C.E. Beta-hydroxybutyrate potentiates GABA-A-mediated inhibitory postsynaptic potentials in immature hippocampal CA1 neurons. Epilepsia. 39(Suppl. 6):1998;125.
    • (1998) Epilepsia , vol.39 , Issue.SUPPL. 6 , pp. 125
    • Ge, S.1    Niesen, C.E.2
  • 12
    • 0032500529 scopus 로고    scopus 로고
    • Mechanism of cloned ATP-sensitive potassium activation by oleoyl-CoA
    • Gribble F.M., Proks P., Corkey B.E., Ashcroft F.M. Mechanism of cloned ATP-sensitive potassium activation by oleoyl-CoA. J. Biol. Chem. 273:1998;26383-26387.
    • (1998) J. Biol. Chem. , vol.273 , pp. 26383-26387
    • Gribble, F.M.1    Proks, P.2    Corkey, B.E.3    Ashcroft, F.M.4
  • 13
    • 0026649107 scopus 로고
    • Two sites for adenine-nucleotide regulation of ATP-sensitive potassium channels in mouse pancreatic beta-cells and HIT cells
    • Hopkins W.F., Fatherazi S., Peter-Riesch B., Corkey B.E., Cook D.L. Two sites for adenine-nucleotide regulation of ATP-sensitive potassium channels in mouse pancreatic beta-cells and HIT cells. J. Membr. Biol. 129:1992;287-295.
    • (1992) J. Membr. Biol. , vol.129 , pp. 287-295
    • Hopkins, W.F.1    Fatherazi, S.2    Peter-Riesch, B.3    Corkey, B.E.4    Cook, D.L.5
  • 14
    • 0030756197 scopus 로고    scopus 로고
    • Ketogenic diet: Effects on expression of kindled seizures and behavior in adult rats
    • Hori A., Tandon P., Holmes G.L., Stafstrom C.E. Ketogenic diet: effects on expression of kindled seizures and behavior in adult rats. Epilepsia. 38:1997;750-758.
    • (1997) Epilepsia , vol.38 , pp. 750-758
    • Hori, A.1    Tandon, P.2    Holmes, G.L.3    Stafstrom, C.E.4
  • 15
    • 0029875965 scopus 로고    scopus 로고
    • Brain glucose metabolism is controlled by amplification and desensitization of the neuronal insulin receptor
    • Hoyer S., Henneberg N., Knapp S., Lannert H., Martin E. Brain glucose metabolism is controlled by amplification and desensitization of the neuronal insulin receptor. Ann. NY Acad. Sci. 777:1996;374-379.
    • (1996) Ann. NY Acad. Sci. , vol.777 , pp. 374-379
    • Hoyer, S.1    Henneberg, N.2    Knapp, S.3    Lannert, H.4    Martin, E.5
  • 16
    • 0017143254 scopus 로고
    • Ketonemia and seizures: Metabolic and anticonvulsant effects of two ketogenic diets in childhood
    • Huttenlocher P.R. Ketonemia and seizures: metabolic and anticonvulsant effects of two ketogenic diets in childhood. Pediatr. Res. 10:1976;536-540.
    • (1976) Pediatr. Res. , vol.10 , pp. 536-540
    • Huttenlocher, P.R.1
  • 17
    • 0033556240 scopus 로고    scopus 로고
    • Decreased ATP synthesis is phenotypically expressed during increased energy demand in fibroblasts containing mitochondrial tRNA mutations
    • James A.M., Sheard P.W., Wei Y.H., Murphy M.P. Decreased ATP synthesis is phenotypically expressed during increased energy demand in fibroblasts containing mitochondrial tRNA mutations. Eur. J. Biochem. 259:1999;462-469.
    • (1999) Eur. J. Biochem. , vol.259 , pp. 462-469
    • James, A.M.1    Sheard, P.W.2    Wei, Y.H.3    Murphy, M.P.4
  • 18
    • 0032832401 scopus 로고    scopus 로고
    • Blood-brain barrier, ion hemostasis and epilepsy: Possible implications towards the understanding of ketogenic diet mechanisms
    • Janigro D. Blood-brain barrier, ion hemostasis and epilepsy: possible implications towards the understanding of ketogenic diet mechanisms. Epilepsy Res. 37:1999;223-232.
    • (1999) Epilepsy Res. , vol.37 , pp. 223-232
    • Janigro, D.1
  • 20
    • 0028149787 scopus 로고
    • Anticonvulsant activity of neurosteroids: Correlation with gamma-aminobutyric acid-evoked chloride current potentiation
    • Kokate T.G., Svensson B.E., Rogawski M.A. Anticonvulsant activity of neurosteroids: correlation with gamma-aminobutyric acid-evoked chloride current potentiation. J. Pharmacol. Exp. Ther. 270:1994;1223-1229.
    • (1994) J. Pharmacol. Exp. Ther. , vol.270 , pp. 1223-1229
    • Kokate, T.G.1    Svensson, B.E.2    Rogawski, M.A.3
  • 22
    • 0029681709 scopus 로고    scopus 로고
    • Effect of low-carbohydrate-ketogenic diet on metabolic and hormonal responses to graded exercise in men
    • Langfort J., Pilis W., Zarzeczny R., Nazar K., Kaciuba-U'scilko H. Effect of low-carbohydrate-ketogenic diet on metabolic and hormonal responses to graded exercise in men. J. Physiol. Pharm. 47:1996;361-371.
    • (1996) J. Physiol. Pharm. , vol.47 , pp. 361-371
    • Langfort, J.1    Pilis, W.2    Zarzeczny, R.3    Nazar, K.4    Kaciuba-U'scilko, H.5
  • 23
    • 0032883708 scopus 로고    scopus 로고
    • Age-dependent pathways of brain energy metabolism in the suckling rat, a natural model of the ketogeniic diet
    • Nehlig A. Age-dependent pathways of brain energy metabolism in the suckling rat, a natural model of the ketogeniic diet. Epilepsy Res. 37:1999;211-221.
    • (1999) Epilepsy Res. , vol.37 , pp. 211-221
    • Nehlig, A.1
  • 24
    • 0030755496 scopus 로고    scopus 로고
    • The ketogenic diet revisited: Back to the future
    • Nordli D.R. Jr, DeVivo D.C. The ketogenic diet revisited: back to the future. Epilepsia. 38:1997;743-749.
    • (1997) Epilepsia , vol.38 , pp. 743-749
    • Nordli D.R., Jr.1    DeVivo, D.C.2
  • 25
    • 0006869561 scopus 로고    scopus 로고
    • Alterations in cerebral metabolism with the ketogenic diet
    • Novotny E.J. Jr, Chen J., Rothman D.L. Alterations in cerebral metabolism with the ketogenic diet. Epilepsia. 38(Suppl. 8):1997;147.
    • (1997) Epilepsia , vol.38 , Issue.SUPPL. 8 , pp. 147
    • Novotny E.J., Jr.1    Chen, J.2    Rothman, D.L.3
  • 26
    • 0031863989 scopus 로고    scopus 로고
    • Taurine efflux and intracellular pH during astrocyte volume regulation
    • Olson J.E., Putnam R.W., Evers J.A., Munoz N. Taurine efflux and intracellular pH during astrocyte volume regulation. Adv. Exp. Med. Biol. 442:1998;229-235.
    • (1998) Adv. Exp. Med. Biol. , vol.442 , pp. 229-235
    • Olson, J.E.1    Putnam, R.W.2    Evers, J.A.3    Munoz, N.4
  • 28
    • 0031239202 scopus 로고    scopus 로고
    • Does astrocytic glycogen benefit axon function and survival in CNS white matter during glucose deprivation?
    • Ransom B.R., Fern R. Does astrocytic glycogen benefit axon function and survival in CNS white matter during glucose deprivation? Glia. 21:1997;134-141.
    • (1997) Glia , vol.21 , pp. 134-141
    • Ransom, B.R.1    Fern, R.2
  • 29
    • 0025873186 scopus 로고
    • Glucose concentration inversely alters neocortical slice excitability through an osmotic effect
    • Rosen A.S., Andrew R.D. Glucose concentration inversely alters neocortical slice excitability through an osmotic effect. Brain Res. 555:1991;58-64.
    • (1991) Brain Res. , vol.555 , pp. 58-64
    • Rosen, A.S.1    Andrew, R.D.2
  • 30
    • 18844464366 scopus 로고    scopus 로고
    • Metabolic and endocrine aspects of the ketogenic diet
    • Sankar R., Sotero de Menezes M. Metabolic and endocrine aspects of the ketogenic diet. Epilepsy Res. 37:1999;191-201.
    • (1999) Epilepsy Res. , vol.37 , pp. 191-201
    • Sankar, R.1    Sotero De Menezes, M.2
  • 32
    • 0030919448 scopus 로고    scopus 로고
    • Electrophysiological changes in rat hippocampal pyramidal neurons produced by cholecystokinin octapeptide
    • Shinohara S., Kawasaki K. Electrophysiological changes in rat hippocampal pyramidal neurons produced by cholecystokinin octapeptide. Neuroscience. 78:1997;1005-1016.
    • (1997) Neuroscience , vol.78 , pp. 1005-1016
    • Shinohara, S.1    Kawasaki, K.2
  • 33
    • 0030859670 scopus 로고    scopus 로고
    • Influence of dietary fat on the activities of subcellular membrane-bound enzymes from different regions of rat brain
    • Srinivasarao P., Narayanareddy K., Vajreswari A., Rupalatha M., Prakash P.S., Rao P. Influence of dietary fat on the activities of subcellular membrane-bound enzymes from different regions of rat brain. Neurochem. Int. 6:1997;789-794.
    • (1997) Neurochem. Int. , vol.6 , pp. 789-794
    • Srinivasarao, P.1    Narayanareddy, K.2    Vajreswari, A.3    Rupalatha, M.4    Prakash, P.S.5    Rao, P.6
  • 35
    • 0002402194 scopus 로고    scopus 로고
    • Ketogenic diet induces ketonemia and inhibits seizures in epileptic EL mice
    • Todorova M., Pushpa T., Madore R.A., Stafstrom C.E., Seyfried T.N. Ketogenic diet induces ketonemia and inhibits seizures in epileptic EL mice. Epilepsia. 39(Suppl. 6):1998;38-39.
    • (1998) Epilepsia , vol.39 , Issue.SUPPL. 6 , pp. 38-39
    • Todorova, M.1    Pushpa, T.2    Madore, R.A.3    Stafstrom, C.E.4    Seyfried, T.N.5
  • 36
    • 0025350861 scopus 로고
    • Proton inhibition of N-methyl-D-aspartate receptors in cerebellar neurons
    • Traynelis S.F., Cull-Candy S.G. Proton inhibition of N-methyl-D-aspartate receptors in cerebellar neurons. Nature. 345:1990;347-350.
    • (1990) Nature , vol.345 , pp. 347-350
    • Traynelis, S.F.1    Cull-Candy, S.G.2
  • 37
    • 0030296655 scopus 로고    scopus 로고
    • Antiseizure activity of insulin: Insulin inhibits pentylenetetrazole, penicillin and kainic acid-induced seizures in rats
    • Uysal H., Kuli P., Caglar S., Inan L.E., Akarsu E.S., Palaoglu O. et al. Antiseizure activity of insulin: insulin inhibits pentylenetetrazole, penicillin and kainic acid-induced seizures in rats. Epilepsy Res. 25:1996;185-190.
    • (1996) Epilepsy Res. , vol.25 , pp. 185-190
    • Uysal, H.1    Kuli, P.2    Caglar, S.3    Inan, L.E.4    Akarsu, E.S.5    Palaoglu, O.6
  • 38
    • 0030879895 scopus 로고    scopus 로고
    • The effects of lactate and beta-hydroxybutyrate on the energy metabolism and neural activity of hippocampal slices from adult and immature rat
    • Wada H., Okada Y., Nabetani M., Nakamura H. The effects of lactate and beta-hydroxybutyrate on the energy metabolism and neural activity of hippocampal slices from adult and immature rat. Develop. Brain Res. 101:1997;1-7.
    • (1997) Develop. Brain Res. , vol.101 , pp. 1-7
    • Wada, H.1    Okada, Y.2    Nabetani, M.3    Nakamura, H.4
  • 39
    • 0030800192 scopus 로고    scopus 로고
    • Recruitment of functional GABA(A) receptors to postsynaptic domains by insulin
    • Wan Q., Xiong Z.G., Man H.Y., Ackerley C.A., Braunton J., Lu W.Y. et al. Recruitment of functional GABA(A) receptors to postsynaptic domains by insulin. Nature. 388:1997;686-690.
    • (1997) Nature , vol.388 , pp. 686-690
    • Wan, Q.1    Xiong, Z.G.2    Man, H.Y.3    Ackerley, C.A.4    Braunton, J.5    Lu, W.Y.6
  • 42
    • 0032577376 scopus 로고    scopus 로고
    • Signals that regulate food intake and energy homeostasis
    • Woods S.C., Seeley R.J., Porte D. Jr, Schwartz M.W. Signals that regulate food intake and energy homeostasis. Science. 280:1998;1378-1383.
    • (1998) Science , vol.280 , pp. 1378-1383
    • Woods, S.C.1    Seeley, R.J.2    Porte D., Jr.3    Schwartz, M.W.4


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.