메뉴 건너뛰기




Volumn 69, Issue 2, 1997, Pages 682-692

Effects of ketone bodies on astrocyte amino acid metabolism

Author keywords

Aspartate; Astrocytes; Epilepsy; GABA; Glutamate; Ketone bodies

Indexed keywords

3 HYDROXYBUTYRIC ACID; 4 AMINOBUTYRIC ACID; ACETIC ACID; ACETOACETIC ACID; AMINO ACID; CITRIC ACID; GLUTAMATE AMMONIA LIGASE; GLUTAMIC ACID; GLUTAMINE; KETONE BODY;

EID: 0030853393     PISSN: 00223042     EISSN: None     Source Type: Journal    
DOI: 10.1046/j.1471-4159.1997.69020682.x     Document Type: Article
Times cited : (58)

References (75)
  • 2
    • 0026020414 scopus 로고
    • Fatty acid oxidation and ketogenesis by astrocytes in primary culture
    • Auestad N., Korsak R. A., Morrow J. W., and Edmond J. (1991) Fatty acid oxidation and ketogenesis by astrocytes in primary culture. J. Neurochem. 56, 1376-1386.
    • (1991) J. Neurochem. , vol.56 , pp. 1376-1386
    • Auestad, N.1    Korsak, R.A.2    Morrow, J.W.3    Edmond, J.4
  • 4
    • 0002775177 scopus 로고
    • Ketogenic diets for treatment of childhood epilepsy
    • (Walser M., Imbembo A. L., Margolis S., and Eifert G., eds), W. B. Saunders, Philadelphia
    • Barbosa E., Freeman J., and Elfert G. (1984) Ketogenic diets for treatment of childhood epilepsy, in Nutritional Management: The Johns Hopkins Handbook (Walser M., Imbembo A. L., Margolis S., and Eifert G., eds), pp. 272-292. W. B. Saunders, Philadelphia.
    • (1984) Nutritional Management: The Johns Hopkins Handbook , pp. 272-292
    • Barbosa, E.1    Freeman, J.2    Elfert, G.3
  • 5
    • 0008732725 scopus 로고
    • Compartmentation of amino acid metabolism
    • (Lajtha A., ed), Plenum Press, New York
    • Berl S. and Clarke D. D. (1969) Compartmentation of amino acid metabolism, in Handbook of Neurochemistry, Vol. 2 (Lajtha A., ed), pp. 447-472. Plenum Press, New York.
    • (1969) Handbook of Neurochemistry , vol.2 , pp. 447-472
    • Berl, S.1    Clarke, D.D.2
  • 6
    • 0343720231 scopus 로고
    • Metabolism of branched-chain amino acids in astroglial-rich primary culture
    • Bixel M. G. and Hamprecht B. (1994) Metabolism of branched-chain amino acids in astroglial-rich primary culture. (Abstr.) J. Neurochem. 63 (Suppl.), S62A.
    • (1994) J. Neurochem. , vol.63 , Issue.SUPPL.
    • Bixel, M.G.1    Hamprecht, B.2
  • 7
    • 0018840291 scopus 로고
    • The development of enzymes of energy metabolism in the brain of a precocial (guinea pig) and non-precocial (rat) species
    • Booth R. F. G., Patel T. B., and Clark J. B. (1980) The development of enzymes of energy metabolism in the brain of a precocial (guinea pig) and non-precocial (rat) species. J. Neurochem. 34, 17-25.
    • (1980) J. Neurochem. , vol.34 , pp. 17-25
    • Booth, R.F.G.1    Patel, T.B.2    Clark, J.B.3
  • 8
    • 0026764056 scopus 로고
    • Seizure-related elevations of extracellular amino acids in human focal epilepsy
    • Carlson H., Ronne-Engstrum E., Ungerstedt U., and Hillered L. (1992) Seizure-related elevations of extracellular amino acids in human focal epilepsy. Neurosci. Lett. 140, 30-32.
    • (1992) Neurosci. Lett. , vol.140 , pp. 30-32
    • Carlson, H.1    Ronne-Engstrum, E.2    Ungerstedt, U.3    Hillered, L.4
  • 9
    • 0023115695 scopus 로고
    • Ketone body enzyme activities in purified neurons, astrocytes and oligodendroglia
    • Chechik T., Roeder L. M., Tildon J. T., and Poduslo S. E. (1987) Ketone body enzyme activities in purified neurons, astrocytes and oligodendroglia. Neurochem. Int. 10, 95-99.
    • (1987) Neurochem. Int. , vol.10 , pp. 95-99
    • Chechik, T.1    Roeder, L.M.2    Tildon, J.T.3    Poduslo, S.E.4
  • 10
    • 0023879595 scopus 로고
    • Influence of the malate-aspartate shuttle on oxidative metabolism in synaptosomes
    • Cheeseman A. J. and Clark J. B. (1988) Influence of the malate-aspartate shuttle on oxidative metabolism in synaptosomes. J. Neurochem. 50, 1559-1565.
    • (1988) J. Neurochem. , vol.50 , pp. 1559-1565
    • Cheeseman, A.J.1    Clark, J.B.2
  • 11
    • 0028009975 scopus 로고
    • Valproate increases glutaminase and decreases glutamine synthetase activities in primary cultures of rat brain astrocytes
    • Collins R. M. Jr., Zielke H. R., and Woody R. C. (1994) Valproate increases glutaminase and decreases glutamine synthetase activities in primary cultures of rat brain astrocytes. J. Neurochem. 62, 1137-1143.
    • (1994) J. Neurochem. , vol.62 , pp. 1137-1143
    • Collins Jr., R.M.1    Zielke, H.R.2    Woody, R.C.3
  • 12
    • 0023265045 scopus 로고
    • + gradients, and neurotransmitter amino acid levels in isolated rat brain synaptosomes
    • + gradients, and neurotransmitter amino acid levels in isolated rat brain synaptosomes. J. Neurochem. 49, 1229-1240.
    • (1987) J. Neurochem. , vol.49 , pp. 1229-1240
    • Dagani, F.1    Erecińska, M.2
  • 13
    • 0002114142 scopus 로고
    • The effects of ketone bodies on glucose utilization
    • (Passoneau J. V., Hawkins R. A., Lust W. D., and Welsh F. A., eds), Williams and Wilkins, Baltimore
    • DeVivo D. C. (1980) The effects of ketone bodies on glucose utilization, in Cerebral Metabolism and Neural Function (Passoneau J. V., Hawkins R. A., Lust W. D., and Welsh F. A., eds), pp. 243-254. Williams and Wilkins, Baltimore.
    • (1980) Cerebral Metabolism and Neural Function , pp. 243-254
    • DeVivo, D.C.1
  • 14
    • 0001219640 scopus 로고
    • Release of EAA: Animal studies and epileptic foci studies in humans
    • (Meldrum B. S., Moroni F., Woods J. H., and Simon R. P., eds), Raven Press, New York
    • Do K. Q., Klancnik J., Gahwiler B. H., Perschak H., Wieser H. G., and Cuenod M. (1991) Release of EAA: animal studies and epileptic foci studies in humans, in Excitatory Amino Acids (Meldrum B. S., Moroni F., Woods J. H., and Simon R. P., eds), pp. 677-685. Raven Press, New York.
    • (1991) Excitatory Amino Acids , pp. 677-685
    • Do, K.Q.1    Klancnik, J.2    Gahwiler, B.H.3    Perschak, H.4    Wieser, H.G.5    Cuenod, M.6
  • 15
    • 0029833561 scopus 로고    scopus 로고
    • Regulation of GABA level in rat brain synaptosomes: Fluxes through enzymes of the GABA shunt and effects of glutamate, calcium and ketone bodies
    • Erecińska M., Nelson D., Daikhin Y., and Yudkoff M. (1996) Regulation of GABA level in rat brain synaptosomes: fluxes through enzymes of the GABA shunt and effects of glutamate, calcium and ketone bodies. J. Neurochem. 67, 2325-2334.
    • (1996) J. Neurochem. , vol.67 , pp. 2325-2334
    • Erecińska, M.1    Nelson, D.2    Daikhin, Y.3    Yudkoff, M.4
  • 16
    • 0021062309 scopus 로고
    • Use of β-methylene-D,L-aspartate to assess the role of aspartate amino-transferase in cerebral oxidative metabolism
    • Fitzpatrick S. M., Cooper A. J. L., and Duffy T. E. (1983) Use of β-methylene-D,L-aspartate to assess the role of aspartate amino-transferase in cerebral oxidative metabolism. J. Neurochem. 41, 1370-1383.
    • (1983) J. Neurochem. , vol.41 , pp. 1370-1383
    • Fitzpatrick, S.M.1    Cooper, A.J.L.2    Duffy, T.E.3
  • 17
    • 0025973578 scopus 로고
    • Enhanced aspartate release from hippocampal slices of epileptic (El) mice
    • Flavin H. J., Wieraszko A., and Seyfried T. N. (1991) Enhanced aspartate release from hippocampal slices of epileptic (El) mice. J. Neurochem. 56, 1007-1011.
    • (1991) J. Neurochem. , vol.56 , pp. 1007-1011
    • Flavin, H.J.1    Wieraszko, A.2    Seyfried, T.N.3
  • 18
    • 0027265530 scopus 로고
    • Aspartate and glutamate mediate excitatory synaptic transmission in area CA1 of the hippocampus
    • Fleck M. W., Henze D. A., Barrionuevo G., and Palmer A. M. (1993) Aspartate and glutamate mediate excitatory synaptic transmission in area CA1 of the hippocampus. J. Neurosci. 13, 3944-3955.
    • (1993) J. Neurosci. , vol.13 , pp. 3944-3955
    • Fleck, M.W.1    Henze, D.A.2    Barrionuevo, G.3    Palmer, A.M.4
  • 19
    • 0021763961 scopus 로고
    • Use of t-butyldimethylsilylation in the GC-MS analysis of physiologic compounds found in the plasma using electron-impact ionization
    • Frederick W. S., Berg P. J., Miles A. J. M., and Haymond M. W. (1984) Use of t-butyldimethylsilylation in the GC-MS analysis of physiologic compounds found in the plasma using electron-impact ionization. Anal. Biochem. 141, 101-109.
    • (1984) Anal. Biochem. , vol.141 , pp. 101-109
    • Frederick, W.S.1    Berg, P.J.2    Miles, A.J.M.3    Haymond, M.W.4
  • 20
    • 0025153617 scopus 로고
    • Use of traditional ketogenic diet for treatment of intractable epilepsy
    • Gasch A. T. (1990) Use of traditional ketogenic diet for treatment of intractable epilepsy. J. Am. Diet. Assoc. 90, 1433-1434.
    • (1990) J. Am. Diet. Assoc. , vol.90 , pp. 1433-1434
    • Gasch, A.T.1
  • 21
    • 0016596344 scopus 로고
    • Induction processes in blood-brain transfer of ketone bodies during starvation
    • Gjedde A. and Crone C. (1975) Induction processes in blood-brain transfer of ketone bodies during starvation. Am. J. Physiol. 229, 1165-1169.
    • (1975) Am. J. Physiol. , vol.229 , pp. 1165-1169
    • Gjedde, A.1    Crone, C.2
  • 22
    • 0025864422 scopus 로고
    • Comparative effect of transient global ischemia on extracellular levels of glutamate, glycine and γ-aminobutyric acid in vulnerable and nonvulnerable brain regions in the rat
    • Globus M. Y.-T., Busto R., Martinez E., Valdés I., Dietrich W. D., and Ginsberg M. D. (1991) Comparative effect of transient global ischemia on extracellular levels of glutamate, glycine and γ-aminobutyric acid in vulnerable and nonvulnerable brain regions in the rat. J. Neurochem. 57, 470-478.
    • (1991) J. Neurochem. , vol.57 , pp. 470-478
    • Globus, M.Y.-T.1    Busto, R.2    Martinez, E.3    Valdés, I.4    Dietrich, W.D.5    Ginsberg, M.D.6
  • 24
    • 0022552442 scopus 로고
    • Regional ketone body utilization by rat brain in starvation and diabetes
    • Hawkins R. A., Mans A. M., and Davis D. W. (1986) Regional ketone body utilization by rat brain in starvation and diabetes. Am. J. Physiol. 250, E168-E178.
    • (1986) Am. J. Physiol. , vol.250
    • Hawkins, R.A.1    Mans, A.M.2    Davis, D.W.3
  • 25
    • 0019166072 scopus 로고
    • Interactions between neurons and astrocytes in the turnover of GABA and glutamate
    • Hertz L. and Schousboe A. (1980) Interactions between neurons and astrocytes in the turnover of GABA and glutamate. Brain Res. Bull. 5, 389-395.
    • (1980) Brain Res. Bull. , vol.5 , pp. 389-395
    • Hertz, L.1    Schousboe, A.2
  • 26
    • 0020972316 scopus 로고
    • o-Phthalaldehyde precolumn derivatization and reversed-phase high performance liquid chromatography of polypeptide hydrolysates and physiologic fluids
    • Jones B. N. and Gilligan T. P. (1983) o-Phthalaldehyde precolumn derivatization and reversed-phase high performance liquid chromatography of polypeptide hydrolysates and physiologic fluids. J. Chromatogr. 266, 471-482.
    • (1983) J. Chromatogr. , vol.266 , pp. 471-482
    • Jones, B.N.1    Gilligan, T.P.2
  • 28
    • 0023653356 scopus 로고
    • Aminooxyacetic acid inhibits the malate-aspartate shuttle in isolated nerve terminals and prevents the mitochondria from utilizing glycolytic substrates
    • Kauppinen R. A., Sihra T. S., and Nicholls D. G. (1987) Aminooxyacetic acid inhibits the malate-aspartate shuttle in isolated nerve terminals and prevents the mitochondria from utilizing glycolytic substrates. Biochim. Biophys. Acta 930, 173-178.
    • (1987) Biochim. Biophys. Acta , vol.930 , pp. 173-178
    • Kauppinen, R.A.1    Sihra, T.S.2    Nicholls, D.G.3
  • 29
    • 0020556337 scopus 로고
    • Cultures of purified rat astrocytes in serum free medium supplemented with mitogen
    • Kim S. U., Stern J., Kim M. W., and Pleasure D. E. (1983) Cultures of purified rat astrocytes in serum free medium supplemented with mitogen. Brain Res. 274, 79-86.
    • (1983) Brain Res. , vol.274 , pp. 79-86
    • Kim, S.U.1    Stern, J.2    Kim, M.W.3    Pleasure, D.E.4
  • 30
    • 0027465673 scopus 로고
    • Purification of cytosolic malic enzyme from bovine brain, generation of monoclonal antibodies, and immunocytochemical localization of the enzyme in glial cells of neural primary cultures
    • Kurz G. M., Wiesinger H., and Hamprecht B. (1993) Purification of cytosolic malic enzyme from bovine brain, generation of monoclonal antibodies, and immunocytochemical localization of the enzyme in glial cells of neural primary cultures. J. Neurochem. 60, 1467-1474.
    • (1993) J. Neurochem. , vol.60 , pp. 1467-1474
    • Kurz, G.M.1    Wiesinger, H.2    Hamprecht, B.3
  • 31
    • 0344249143 scopus 로고
    • Monoclonal antibodies recognize individual neurofilament triplet proteins
    • Lee V., Wu H. L., and Schaepfer W. W. (1982) Monoclonal antibodies recognize individual neurofilament triplet proteins. Proc. Natl. Acad. Sci. USA 79, 6089-6092.
    • (1982) Proc. Natl. Acad. Sci. USA , vol.79 , pp. 6089-6092
    • Lee, V.1    Wu, H.L.2    Schaepfer, W.W.3
  • 32
    • 0025818997 scopus 로고
    • Autoreceptor regulation of glutamate and aspartate release from slices of the hippocampal CA1 area
    • Martin D., Bustos G. A., Bowe M. A., Bray S. D., and Nadler J. V. (1991) Autoreceptor regulation of glutamate and aspartate release from slices of the hippocampal CA1 area. J. Neurochem. 56, 1647-1655.
    • (1991) J. Neurochem. , vol.56 , pp. 1647-1655
    • Martin, D.1    Bustos, G.A.2    Bowe, M.A.3    Bray, S.D.4    Nadler, J.V.5
  • 33
    • 0027727915 scopus 로고
    • Regulation of energy metabolism in synaptic terminals and cultured rat brain astrocytes: Differences revealed using aminooxyacetate
    • McKenna M. C., Tildon J. T., Stevenson J. H., Boatright R., and Huang S. (1994) Regulation of energy metabolism in synaptic terminals and cultured rat brain astrocytes: differences revealed using aminooxyacetate. Dev. Neurosci. 15, 320-329.
    • (1994) Dev. Neurosci. , vol.15 , pp. 320-329
    • McKenna, M.C.1    Tildon, J.T.2    Stevenson, J.H.3    Boatright, R.4    Huang, S.5
  • 34
    • 0029619279 scopus 로고
    • Regulation of mitochondrial and cytosolic malic enzymes from cultured rat brain astrocytes
    • McKenna M. C., Tildon J. T., Stevenson J. H., Huang X., and Kingwell K. G. (1995) Regulation of mitochondrial and cytosolic malic enzymes from cultured rat brain astrocytes. Neurochem. Res. 20, 1491-1501.
    • (1995) Neurochem. Res. , vol.20 , pp. 1491-1501
    • McKenna, M.C.1    Tildon, J.T.2    Stevenson, J.H.3    Huang, X.4    Kingwell, K.G.5
  • 35
    • 0028535070 scopus 로고
    • The role of glutamate in epilepsy and other CNS disorders
    • Meldrum B. S. (1994) The role of glutamate in epilepsy and other CNS disorders. Neurology 44, S14-S23.
    • (1994) Neurology , vol.44
    • Meldrum, B.S.1
  • 36
    • 0015606568 scopus 로고
    • The acetoacetyl CoA thiolases of rat brain and their relative activities during postnatal development
    • Middleton B. (1973) The acetoacetyl CoA thiolases of rat brain and their relative activities during postnatal development. Biochem. J. 132, 731-737.
    • (1973) Biochem. J. , vol.132 , pp. 731-737
    • Middleton, B.1
  • 37
    • 0027392957 scopus 로고
    • Extracellular amino acid levels in hippocampus during pilocarpine-induced seizures
    • Millan M. H., Chapman A. G., and Meldrum B. S. (1993) Extracellular amino acid levels in hippocampus during pilocarpine-induced seizures. Epilepsy Res. 14, 139-148.
    • (1993) Epilepsy Res. , vol.14 , pp. 139-148
    • Millan, M.H.1    Chapman, A.G.2    Meldrum, B.S.3
  • 38
    • 0013833140 scopus 로고
    • Metal ion interactions and glutamine synthetase activity: Effect of pH on biosynthetic and transferase activity using Mg, Mn, Co and Fe(II) ions
    • Monder D. (1965) Metal ion interactions and glutamine synthetase activity: effect of pH on biosynthetic and transferase activity using Mg, Mn, Co and Fe(II) ions. Biochemistry 4, 2677-2686.
    • (1965) Biochemistry , vol.4 , pp. 2677-2686
    • Monder, D.1
  • 39
    • 0018776955 scopus 로고
    • Distribution of glutamine synthetase in the rat central nervous system
    • Norenberg M. D. (1979) Distribution of glutamine synthetase in the rat central nervous system. J. Histochem. Cytochem. 27, 756-762.
    • (1979) J. Histochem. Cytochem. , vol.27 , pp. 756-762
    • Norenberg, M.D.1
  • 41
    • 0014970829 scopus 로고
    • Activities of enzymes of ketone-body utilization in brain and other tissues of suckling rats
    • Page M. A., Krebs H. A., and Williamson D. H. (1971) Activities of enzymes of ketone-body utilization in brain and other tissues of suckling rats. Biochem. J. 121, 49-53.
    • (1971) Biochem. J. , vol.121 , pp. 49-53
    • Page, M.A.1    Krebs, H.A.2    Williamson, D.H.3
  • 42
    • 0018848460 scopus 로고
    • Starvation induced changes in transport of ketone bodies across the blood-brain barrier
    • Pollay M. and Stevens F. A. (1980) Starvation induced changes in transport of ketone bodies across the blood-brain barrier. J. Neurosci. Res. 5, 163-172.
    • (1980) J. Neurosci. Res. , vol.5 , pp. 163-172
    • Pollay, M.1    Stevens, F.A.2
  • 43
    • 0019316285 scopus 로고
    • Equilibrium substrate binding studies of the malic enzyme of pigeon liver. Equivalence of nucleotide sites and anticooperativity associated with the binding of L-malate to the enzyme-manganese(II)-reduced nicotinamide adenine dinucleotide phosphate ternary complex
    • Pry T. A. and Hsu R. Y. (1980) Equilibrium substrate binding studies of the malic enzyme of pigeon liver. Equivalence of nucleotide sites and anticooperativity associated with the binding of L-malate to the enzyme-manganese(II)-reduced nicotinamide adenine dinucleotide phosphate ternary complex. Biochemistry 19, 951-962.
    • (1980) Biochemistry , vol.19 , pp. 951-962
    • Pry, T.A.1    Hsu, R.Y.2
  • 44
    • 0025350795 scopus 로고
    • Endogenous aspartate release in the rat hippocampus inhibited by M2 "cardiac" muscarinic receptors
    • Raiteri M., Marchi M., Costi A., and Volpe G. (1990) Endogenous aspartate release in the rat hippocampus inhibited by M2 "cardiac" muscarinic receptors. Eur. J. Pharmacol. 177, 181-187.
    • (1990) Eur. J. Pharmacol. , vol.177 , pp. 181-187
    • Raiteri, M.1    Marchi, M.2    Costi, A.3    Volpe, G.4
  • 45
    • 0024598230 scopus 로고
    • Activities of pyruvate dehydrogenase, enzymes of citric acid cycle, and aminotransferases in the subcellular fractions of cerebral cortex in normal and hyperammonemic rats
    • Ratnakumari L. and Murthy C. R. K. (1989) Activities of pyruvate dehydrogenase, enzymes of citric acid cycle, and aminotransferases in the subcellular fractions of cerebral cortex in normal and hyperammonemic rats. Neurochem. Res. 14, 221-228.
    • (1989) Neurochem. Res. , vol.14 , pp. 221-228
    • Ratnakumari, L.1    Murthy, C.R.K.2
  • 46
    • 0026752613 scopus 로고
    • Effects of congenital hyperammonemia on the cerebral and hepatic levels of the intermediates of energy metabolism in spf mice
    • Ratnakumari L., Qureshi I. A., and Butterworth R. F. (1992) Effects of congenital hyperammonemia on the cerebral and hepatic levels of the intermediates of energy metabolism in spf mice. Biochem. Biophys. Res. Commun. 184, 746-751.
    • (1992) Biochem. Biophys. Res. Commun. , vol.184 , pp. 746-751
    • Ratnakumari, L.1    Qureshi, I.A.2    Butterworth, R.F.3
  • 47
    • 0027203913 scopus 로고
    • Effect of L-carnitine on cerebral and hepatic energy metabolites in congenitally hyperammonemic sparse-fur mice and its role during benzoate therapy
    • Ratnakumari L., Qureshi I. A., and Butterworth R. F. (1993) Effect of L-carnitine on cerebral and hepatic energy metabolites in congenitally hyperammonemic sparse-fur mice and its role during benzoate therapy. Metabolism 42, 1039-1046.
    • (1993) Metabolism , vol.42 , pp. 1039-1046
    • Ratnakumari, L.1    Qureshi, I.A.2    Butterworth, R.F.3
  • 48
    • 0018876377 scopus 로고
    • Physiological roles of ketone bodies as substrates and signals in mammalian tissues
    • Robinson A. M. and Williamson D. H. (1980) Physiological roles of ketone bodies as substrates and signals in mammalian tissues. Physiol. Rev. 60, 143-187.
    • (1980) Physiol. Rev. , vol.60 , pp. 143-187
    • Robinson, A.M.1    Williamson, D.H.2
  • 50
    • 0026699650 scopus 로고
    • Stable isotope tracer analysis by GC-MS, including quantification of isotopomer effects
    • Rosenblatt J., Chinkes D., Wolfe M., and Wolfe R. R. (1992) Stable isotope tracer analysis by GC-MS, including quantification of isotopomer effects. Am. J. Physiol. 263, E584-E596.
    • (1992) Am. J. Physiol. , vol.263
    • Rosenblatt, J.1    Chinkes, D.2    Wolfe, M.3    Wolfe, R.R.4
  • 51
    • 0026065784 scopus 로고
    • Changes in citric acid cycle flux and anaplerosis antedate the functional decline in isolated rat hearts utilizing acetoacetate
    • Russell R. R. and Taegtmeyer H. (1991) Changes in citric acid cycle flux and anaplerosis antedate the functional decline in isolated rat hearts utilizing acetoacetate. J. Clin. Invest. 87, 384-390.
    • (1991) J. Clin. Invest. , vol.87 , pp. 384-390
    • Russell, R.R.1    Taegtmeyer, H.2
  • 52
    • 0026518929 scopus 로고
    • Coenzyme A sequestration in rat hearts oxidizing ketone bodies
    • Russell R. R. and Taegtmeyer H. (1992) Coenzyme A sequestration in rat hearts oxidizing ketone bodies. J. Clin. Invest. 89, 968-973.
    • (1992) J. Clin. Invest. , vol.89 , pp. 968-973
    • Russell, R.R.1    Taegtmeyer, H.2
  • 53
    • 0011438434 scopus 로고
    • Regulation of glutamatergic and GABAergic neuronal activity by astroglia cells
    • (Osborne N. N., ed), Pergamon Press, New York
    • Schousboe A. and Hertz L. (1983) Regulation of glutamatergic and GABAergic neuronal activity by astroglia cells, in Principles and Communication Between Neurons (Osborne N. N., ed), pp. 113-142. Pergamon Press, New York.
    • (1983) Principles and Communication between Neurons , pp. 113-142
    • Schousboe, A.1    Hertz, L.2
  • 55
    • 0023890868 scopus 로고
    • Lactate-supported synaptic function in the rat hippocampal slice preparation
    • Schurr A., West C. A., and Rigor B. M. (1988) Lactate-supported synaptic function in the rat hippocampal slice preparation. Science 240, 1326-1328.
    • (1988) Science , vol.240 , pp. 1326-1328
    • Schurr, A.1    West, C.A.2    Rigor, B.M.3
  • 56
    • 0019991447 scopus 로고
    • Glutamine and α-ketoglutarate uptake and metabolism by nerve terminal enriched material from mouse cerebellum
    • Shank R. P. and Campbell G. L.-M. (1982) Glutamine and α-ketoglutarate uptake and metabolism by nerve terminal enriched material from mouse cerebellum. Neurochem. Res. 7, 601-616.
    • (1982) Neurochem. Res. , vol.7 , pp. 601-616
    • Shank, R.P.1    Campbell, G.L.-M.2
  • 57
    • 0021988603 scopus 로고
    • Pyruvate carboxylase: Astrocytic-specific enzyme implicated in replenishment of amino acid neurotransmitter pools
    • Shank R. P., Bennett G. S., Freytag S. O., and Campbell G. L. (1985) Pyruvate carboxylase: astrocytic-specific enzyme implicated in replenishment of amino acid neurotransmitter pools. Brain Res. 329, 364-367.
    • (1985) Brain Res. , vol.329 , pp. 364-367
    • Shank, R.P.1    Bennett, G.S.2    Freytag, S.O.3    Campbell, G.L.4
  • 59
    • 0020514274 scopus 로고
    • On the inability of ketone bodies to serve as the only energy providing substrate for rat heart at physiological work load
    • Taegtmeyer H. (1983) On the inability of ketone bodies to serve as the only energy providing substrate for rat heart at physiological work load. Basic Res. Cardiol. 78, 435-450.
    • (1983) Basic Res. Cardiol. , vol.78 , pp. 435-450
    • Taegtmeyer, H.1
  • 60
    • 0021364298 scopus 로고
    • Glutamine oxidation by dissociated cells and homogenates of rat brain: Kinetics and inhibitor studies
    • Tildon J. T. and Roeder L. M. (1984) Glutamine oxidation by dissociated cells and homogenates of rat brain: kinetics and inhibitor studies. J. Neurochem. 42, 1069-1076.
    • (1984) J. Neurochem. , vol.42 , pp. 1069-1076
    • Tildon, J.T.1    Roeder, L.M.2
  • 61
  • 63
    • 0022245525 scopus 로고
    • Substrate oxidation by isolated rat brain mitochondria and synaptosomes
    • Tildon J. T., Roeder L. M., and Stevenson J. H. (1985) Substrate oxidation by isolated rat brain mitochondria and synaptosomes. J. Neurosci. Res. 14, 207-215.
    • (1985) J. Neurosci. Res. , vol.14 , pp. 207-215
    • Tildon, J.T.1    Roeder, L.M.2    Stevenson, J.H.3
  • 64
    • 0027962692 scopus 로고
    • Transport of 3-hydroxybutyrate by cultured rat brain astrocytes
    • Tildon J. T., McKenna M. C., and Stevenson J. H. Jr. (1994) Transport of 3-hydroxybutyrate by cultured rat brain astrocytes. Neurochem. Res. 19, 1237-1242.
    • (1994) Neurochem. Res. , vol.19 , pp. 1237-1242
    • Tildon, J.T.1    McKenna, M.C.2    Stevenson Jr., J.H.3
  • 65
    • 0027842804 scopus 로고
    • Effect of ischaemia and reperfusion on the extra- and intracellular distribution of glutamate, glutamine, aspartate and GABA in the rat hippocampus, with a note on the effect of the sodium channel blocker BW1003C87
    • Torp R., Arvin B., LePeillet E., Chapman A. G., Ottersen O. P., and Meldrum B. S. (1993) Effect of ischaemia and reperfusion on the extra- and intracellular distribution of glutamate, glutamine, aspartate and GABA in the rat hippocampus, with a note on the effect of the sodium channel blocker BW1003C87. Exp. Brain Res. 96, 365-376.
    • (1993) Exp. Brain Res. , vol.96 , pp. 365-376
    • Torp, R.1    Arvin, B.2    LePeillet, E.3    Chapman, A.G.4    Ottersen, O.P.5    Meldrum, B.S.6
  • 66
    • 0021728238 scopus 로고
    • Glutamine synthetase: The major Mn(II) enzyme in mammalian brain
    • (DeLuca M., Lardy H., and Cross R. L., eds), Academic Press, New York
    • Wedler F. C. and Denman R. B. (1984) Glutamine synthetase: the major Mn(II) enzyme in mammalian brain, in Current Topics in Cell Regulation, Vol. 24 (DeLuca M., Lardy H., and Cross R. L., eds), pp. 153-169. Academic Press, New York.
    • (1984) Current Topics in Cell Regulation , vol.24 , pp. 153-169
    • Wedler, F.C.1    Denman, R.B.2
  • 67
    • 0028137718 scopus 로고
    • Kinetic, ESR and trapping evidence for in vivo binding of Mn(II) to glutamine synthetase in brain cells
    • Wedler F. C. and Ley B. W. (1994) Kinetic, ESR and trapping evidence for in vivo binding of Mn(II) to glutamine synthetase in brain cells. Neurochem. Res. 19, 139-144.
    • (1994) Neurochem. Res. , vol.19 , pp. 139-144
    • Wedler, F.C.1    Ley, B.W.2
  • 68
    • 0028256181 scopus 로고
    • Uptake, release, and metabolism of citrate in neurons and astrocytes in primary cultures
    • Westergaard N., Sonnewald U., Unsgård G., Peng L., Hertz L., and Schousboe A. (1994) Uptake, release, and metabolism of citrate in neurons and astrocytes in primary cultures. J. Neurochem. 62, 1727-1733.
    • (1994) J. Neurochem. , vol.62 , pp. 1727-1733
    • Westergaard, N.1    Sonnewald, U.2    Unsgård, G.3    Peng, L.4    Hertz, L.5    Schousboe, A.6
  • 69
    • 0028879327 scopus 로고
    • Metabolic trafficking between neurons and astrocytes: The glutamate/glutamine cycle revisited
    • Westergaard N., Sonnewald U., and Schousboe A. (1995) Metabolic trafficking between neurons and astrocytes: the glutamate/glutamine cycle revisited. Dev. Neurosci. 17, 203-211.
    • (1995) Dev. Neurosci. , vol.17 , pp. 203-211
    • Westergaard, N.1    Sonnewald, U.2    Schousboe, A.3
  • 70
    • 0001544644 scopus 로고
    • Effects of ketonuria on the course of epilepsy
    • Wilder R. M. (1921) Effects of ketonuria on the course of epilepsy. Mayo Clin. Bull. 2, 307-310.
    • (1921) Mayo Clin. Bull. , vol.2 , pp. 307-310
    • Wilder, R.M.1
  • 71
    • 0001039779 scopus 로고
    • Epilepsy in childhood. III. Results with the ketogenic diet
    • Wilkins L. (1937) Epilepsy in childhood. III. Results with the ketogenic diet. J. Pediatr. 10, 341-357.
    • (1937) J. Pediatr. , vol.10 , pp. 341-357
    • Wilkins, L.1
  • 72
    • 0021037707 scopus 로고
    • Pyruvate carboxylase activity in primary cultures of astrocytes and neurons
    • Yu A. C. H., Drejer J., Hertz L., and Schousboe A. (1983) Pyruvate carboxylase activity in primary cultures of astrocytes and neurons. J. Neurochem. 41, 1484-1487.
    • (1983) J. Neurochem. , vol.41 , pp. 1484-1487
    • Yu, A.C.H.1    Drejer, J.2    Hertz, L.3    Schousboe, A.4
  • 75
    • 0028036798 scopus 로고
    • Tricarboxylic acid cycle in rat brain synaptosomes. Fluxes and interactions with aspartate aminotransferase and malate/aspartate shuttle
    • Yudkoff M., Nelson D., Daikhin Y., and Erecińska M. (1994) Tricarboxylic acid cycle in rat brain synaptosomes. Fluxes and interactions with aspartate aminotransferase and malate/aspartate shuttle. J. Biol. Chem. 269, 27414-27420.
    • (1994) J. Biol. Chem. , vol.269 , pp. 27414-27420
    • Yudkoff, M.1    Nelson, D.2    Daikhin, Y.3    Erecińska, M.4


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.