Regulated interactions between partner and non-partner sensors and response regulators that control glycopeptide resistance gene expression in enterococci

Microbiology

Volumn 145, Issue 8, 1999, Pages 1849-1858

  Arthur, Michel ^a,b   Depardieu, Florence ^a   Courvalin, Patrice ^a  

^a INSTITUT PASTEUR   (France)

^b UNIVERSITÉ PARIS SACLAY   (France)

Author keywords

Cross talk; Enterococci; Glycopeptide resistance; Peptidoglycan; Two component regulatory system

Indexed keywords

BAMBERMYCIN; GLYCOPEPTIDE; PHOSPHATASE; PHOSPHOTRANSFERASE; TEICOPLANIN; VANCOMYCIN;

AMINO ACID SUBSTITUTION; ANTIBIOTIC RESISTANCE; ARTICLE; AUTOPHOSPHORYLATION; BINDING SITE; CONTROLLED STUDY; ENTEROCOCCUS FAECALIS; ENZYME ACTIVATION; ENZYME ACTIVITY; GENE ACTIVATION; GENE CLUSTER; GENE EXPRESSION REGULATION; GENE MAPPING; GENETIC TRANSCRIPTION; NONHUMAN; PLASMID; PRIORITY JOURNAL; PROMOTER REGION; PROTEIN PHOSPHORYLATION; SITE DIRECTED MUTAGENESIS; TRANSCRIPTION REGULATION;

EID: 0032870104     PISSN: 13500872     EISSN: None     Source Type: Journal    
DOI: 10.1099/13500872-145-8-1849     Document Type: Article

References (27)

1. Arthur, M., Molinas, C & Courvalin, P. (1992). The VanS-VanR two-component regulatory system controls synthesis of depsipeptide peptidoglycan precursors in Enterococcus faecium BM4147. J Bacteriol 174, 2582-2591.
2. Arthur, M., Depardieu, F., Snaith, H.A., Reynolds, P.E. & Courvalin, P. (1994). Contribution of VanY D,D-carboxypeptidase to glycopeptide resistance in Enterococcus faecalis by hydrolysis of peptidoglycan precursors. Antimicrob Agents Chemother 38, 1899-1903.
3. Arthur, M., Depardieu, F., Reynolds, P. & Courvalin, P. (1996a). Quantitative analysis of the metabolism of soluble cytoplasmic peptidoglycan precursors of glycopeptide-resistant enterococci. Mol Microbiol 21, 33-44.
4. Arthur, M., Reynolds, P. & Courvalin, P. (1996b). Glycopeptide resistance in enterococci. Trends Microbiol 4, 401-407.
5. Arthur, M., Depardieu, F., Gerbaud, G., Galimand, M., Leclercq, R. & Courvalin, P. (1997). The VanS sensor negatively controls VanR-mediated transcriptional activation of glycopeptide resistance genes of Tn1546 and related elements in the absence of induction. J Bacteriol 179, 97-106.
6. Arthur, M., Depardieu, F., Cabanié, L., Reynolds, P. & Courvalin, P. (1998). Requirement of the VanY and VanX D,D-peptidases for glycopeptide resistance in enterococci. Mol Microbiol 30, 819-830.
7. Ausubel, F. M., Brent, R., Kingston, R. E., Moore, D. D., Seidman, J. G., Smith, J. A. & Struhl, K. (1987). Current Protocols in Molecular Biology. New York: Wiley.
8. Baptista, M., Depardieu, F., Courvalin, P. & Arthur, M. (1996). Specificity of induction of glycopeptide resistance genes in Enterococcus faecalis. Antimicrob Agents Chemother 40, 2291-2295.
9. Baptista, M., Depardieu, F., Reynolds, P., Courvalin, P. & Arthur, M. (1997). Mutations leading to increased levels of resistance to glycopeptide antibiotics in VanB-type enterococci. Mol Microbiol 25, 93-105.
10. Baptista, M., Rodrigues, P., Depardieu, F., Courvalin, P. & Arthur, M. (1999). Single cell analysis of glycopeptide resistance gene expression in teicoplanin-resistant mutants of VanB-type Enterococcus faecalis. Mol Microbiol 32, 17-28.
11. Bugg, T. D. H., Wright G. D., Dutka-Malen, S., Arthur, M., Courvalin, P. & Walsh, C. T. (1991). Molecular basis for vancomycin resistance in Enterococcus faecium BM4147: biosynthesis of a depsipeptide peptidoglycan precursor by vancomycin resistance proteins VanH and VanA. Biochemistry 30, 10408-10415.
12. Courvalin, P. & Carlier, C. (1986). Transposable multiple antibiotic resistance in Streptococcus pneumoniae. Mol Gen Genet 205, 291-297.
13. Cruz-Rodz, A. L. & Gilmore, M. S. (1990). High efficiency introduction of plasmid DNA into glycine treated Enterococcus faecalis by electroporation. Mol Gen Genet 224, 152-154.
14. B two-component regulatory system in Enterococcus faecalis V583. J Bacteriol 178, 1302-1309.
15. Fisher, S., Jiang, W., Wanner, B. & Walsh, C (1995). Cross-talk between the histidine protein kinase VanS and the response regulator PhoB. J Biol Chem 270, 23143-23149.
16. Haldimann, A., Fisher, S. L., Daniels, L. L., Walsh, C. T. & Wanner, B. L. (1997). Transcriptional regulation of the Enterococcus faecium BM4147 vancomycin resistance gene cluster by the VanS-VanR two-component regulatory system in Escherichia coli K-12. J Bacteriol 179, 5903-5913.
17. Handwerger, S. & Kolokathis, A. (1990). Induction of vancomycin resistance in Enterococcus faecium by inhibition of transglycosylation. FEMS Microbiol Lett 70, 167-170.
18. Hoch, J. A. & Silhavy, T. J. (1995). Two-component Signal Transduction. Washington, DC: American Society for Microbiology.
19. Holman, T. R., Wu, Z., Wanner, B. L. &Walsh, C. T. (1994). Identification of the DNA-binding site for the phosphorylated VanR protein required for vancomycin resistance in Enterococcus faecium. Biochemistry 33, 4625-4631.
20. Hsing, W. & Silhavy, T. J. (1997). Function of conserved histidine-243 in phosphatase activity of EnvZ, the sensor for porin osmoregulation in Escherichia coli. J Bacteriol 179, 3729-3735.
21. Jacob, A. E. & Hobbs, S. J. (1974). Conjugal transfer of plasmid-borne multiple antibiotic resistance in Streptococcus faecalis var. zymogenes. J Bacteriol 117, 360-372.
22. Silva, J. C., Haldimann, A., Prahalad, M. K., Walsh, C. T. & Wanner, B. L. (1998). In vivo characterization of the type A and B vancomycin-resistant enterococci (VRE) VanRS two-component systems in Escherichia coli: a nonpathogenic model for studying the VRE signal transduction pathways. Proc Natl Acad Sci USA 95, 11951-11956.
23. Trieu-Cuot, P., Klier, A. & Courvalin, P. (1985). DNA sequences specifying the transcription of the streptococcal kanamycin resistance gene in Escherichia coli and in Bacillus subtilis. Mol Gen Genet 198, 348-352.
24. Trieu-Cuot, P., Carlier, C., Poyart-Salmeron, C. & Courvalin, P. (1990). A pair of mobilizable shuttle vectors conferring resistance to spectinomycin for molecular cloning in Escherichia coli and in Gram-positive bacteria. Nucleic Acids Res 18, 4296.
25. Trieu-Cuot, P., Carlier, C., Poyart-Salmeron, C. & Courvalin, P. (1991). An integrative vector exploiting the transposition properties of Tn1545 for insertional mutagenesis and cloning of genes from gram-positive bacteria. Gene 106, 21-27.
26. Walsh, C., Fisher, S., Park. I.-S., Prahalad, M. & Wu, Z. (1996). Bacterial resistance to vancomycin: five genes and one missing hydrogen bond tell the story. Chem Biol 3, 21-28.
27. Wright, G. D., Holman, T. R. & Walsh, C. T. (1993). Purification and characterization of VanR and the cytosolic domain of VanS: a two-component regulatory system required for vancomycin resistance in Enterococcus faecium BM4147. Biochemistry 32, 5057-5063.