Transcriptional regulation of the Enterococcus faecium BM4147 vancomycin resistance gene cluster by the VanS-VanR two-component regulatory system in Escherichia coli K-12

Journal of Bacteriology

Volumn 179, Issue 18, 1997, Pages 5903-5913

  Haldimann, Andreas ^a   Fisher, Stewart L ^b,c   Daniels, Larry L ^a,d   Walsh, Christopher T ^b   Wanner, Barry L ^a  

^a PURDUE UNIVERSITY   (United States)

^b HARVARD MEDICAL SCHOOL   (United States)

^c Hoffman La Roche Department of Metabolic Diseases   (United States)

^d UNIVERSITY OF THE WEST INDIES   (Jamaica)

Author keywords

[No Author keywords available]

Indexed keywords

PROTEIN HISTIDINE KINASE; RHAMNOSE; UNCLASSIFIED DRUG; VANCOMYCIN;

ANTIBIOTIC RESISTANCE; ARTICLE; ENTEROCOCCUS FAECALIS; ENZYME PHOSPHORYLATION; ESCHERICHIA COLI; GENE CLUSTER; MOLECULAR MODEL; NONHUMAN; PRIORITY JOURNAL; REGULATOR GENE; SIGNAL TRANSDUCTION; STRAIN DIFFERENCE; TRANSCRIPTION REGULATION;

ENTEROCOCCUS FAECALIS; ENTEROCOCCUS FAECIUM; ESCHERICHIA; ESCHERICHIA COLI K12; STREPTOCOCCUS;

EID: 0030883566     PISSN: 00219193     EISSN: None     Source Type: Journal    
DOI: 10.1128/jb.179.18.5903-5913.1997     Document Type: Article

References (54)

1. Arthur, M., F. Depardieu, G. Gerbaud, M. Galimand, R. Leclercq, and P. Courvalin. 1997. The VanS sensor negatively controls VanR-mediated transcriptional activation of glycopeptide resistance genes of Tn1546 and related elements in the absence of induction. J. Bacteriol. 179:97-106.
2. Arthur, M., C. Molinas, and P. Courvalin. 1992. The VanS-VanR two-component regulatory system controls synthesis of depsipeptide peptidoglycan precursors in Enterococcus faecium BM4147. J. Bacteriol. 174:2582-2591.
3. Atlas, R. M., and A. K. Bej. 1990. Detecting bacterial pathogens in environmental water samples by using PCR and gene probes, p. 399-406. In M. A. Innis, D. H. Gelfand, J. J. Sninsky, and T. J. White (ed.), PCR protocols: a guide to methods and applications. Academic Press, Inc., San Diego, Calif.
4. Baptista, M., F. Depardieu, P. Courvalin, and M. Arthur. 1996. Specificity of induction of glycopeptide resistance genes in Enterococcus faecalis. Antimicrob. Agents Chemother. 40:2291-2295.
5. Comess, K. M., L. M. Shewchuk, K. Ivanetich, and C. T. Walsh. 1994. Construction of a synthetic gene for the metalloregulatory protein MerR and analysis of regionally mutated proteins for transcriptional regulation. Biochemistry 33:4175-4186.
6. Daniels, L. L., and B. L. Wanner. Unpublished data.
7. + mutant of EnvZ (EnvZ.N347D), a bifunctional signal transducer of Escherichia coli. J. Biol. Chem. 271:1424-1429.
8. Fisher, S. L., W. Jiang, B. L. Wanner, and C. T. Walsh. 1995. Cross-talk between the histidine protein kinase VanS and the response regulator PhoB: characterization and identification of a VanS domain that inhibits activation of PhoB. J. Biol. Chem. 270:23143-23149.
9. Fisher, S. L., S.-K. Kim, B. L. Wanner, and C. T. Walsh. 1996. Kinetic comparison of the specificity of the vancomycin resistance kinase VanS for two response regulators, VanR and PhoB. Biochemistry 35:4732-4740.
10. BAD promoter. J. Bacteriol. 177:4121-4130.
11. Hakenbeck, R. 1994. Resistance to glycopeptide antibiotics, p. 535-546. In A. Neuberger, L. M. M. van Deenen, J.-M. Ghuysen, and R. Hakenbeck (ed.), New comprehensive biochemistry, vol. 27. Bacterial cell wall. Elsevier Science B. V., Amsterdam, The Netherlands.
12. Haldimann, A., M. K. Prahalad, S. L. Fisher, S.-K. Kim, C. T. Walsh, and B. L. Wanner. 1996. Altered recognition mutants of the response regulator PhoB: a new genetic strategy for studying protein-protein interactions. Proc. Natl. Acad. Sci. USA 93:14361-14366.
13. Haldimann, A., and B. L. Wanner. Unpublished data.
14. Hasan, N., M. Koob, and W. Szybalski. 1994. Escherichia coli genome targeting. I. Cre-lox-mediated in vitro generation of ori plasmids and their in vivo chromosomal integration and retrieval. Gene 150:51-56.
15. Holman, T. R., Z. Wu, B. L. Wanner, and C. T. Walsh. 1994. Identification of the DNA-binding site for the phosphorylated VanR protein required for vancomycin resistance in Enterococcus faecium. Biochemistry 33:4625-4631.
16. Hsing, W., and T. J. Silhavy. 1997. Function of conserved histidine-243 in phosphatase activity of EnvZ, the sensor for porin osmoregulation in Escherichia coli. J. Bacteriol. 179:3729-3735.
17. Jiang, W., A. Haldimann, and B. L. Wanner. Unpublished data.
18. Kamberov, E. S., M. R. Atkinson, P. Chandran, and A. J. Ninfa. 1994. Effect of mutations in Escherichia coli glnL (ntrB), encoding nitrogen regulator II (NRII or NtrB), on the phosphatase activity involved in bacterial nitrogen regulation. J. Biol. Chem. 269:28294-28299.
19. Kim, S.-K., and B. L. Wanner. Unpublished data.
20. Kim, S.-K., M. R. Wilmes-Riesenberg, and B. L. Wanner. 1996. Involvement of the sensor kinase EnvZ in the in vivo activation of the response regulator PhoB by acetyl phosphate. Mol. Microbiol. 22:135-147.
21. Lai, M. H., and D. R. Kirsch. 1996. Induction signals for vancomycin resistance encoded by the vanA gene cluster in Enterococcus faecium. Antimicrob. Agents Chemother. 40:1645-1648.
22. Lazar, S. W., and R. Kolter. 1996. SurA assists the folding of Escherichia coli outer membrane proteins. J. Bacteriol. 178:1770-1773.
23. Lee, T.-Y., K. Makino, H. Shinagawa, and A. Nakata. 1990. Overproduction of acetate kinase activates the phosphate regulon in the absence of the phoR and phoM functions in Escherichia coli. J. Bacteriol. 172:2245-2249.
24. Linn, T., and R. St. Pierre. 1990. Improved vector system for constructing transcriptional fusions that ensures independent translation of lacZ. J. Bacteriol. 172:1077-1084.
25. McCleary, W. R., and J. B. Stock. 1994. Acetyl phosphate and the activation of two-component response regulators. J. Biol. Chem. 269:31567-31572.
26. Metcalf, W. W., W. Jiang, L. L. Daniels, S.-K. Kim, A. Haldimann, and B. L. Wanner. 1996. Conditionally replicative and conjugative plasmids carrying lacZα for cloning, mutagenesis, and allele replacement in bacteria. Plasmid 35:1-13
27. Metcalf, W. W., and B. L. Wanner. 1993. Mutational analysis of an Escherichia coli fourteen-gene operon for phosphonate degradation using TnphoA' elements. J. Bacteriol. 175:3430-3442.
28. Ohlsen, K. L., J. K. Grimsley, and J. A. Hoch. 1994. Deactivation of the sporulation transcription factor Spo0A by the Spo0E protein phosphatase. Proc. Natl. Acad. Sci. USA 91:1756-1760.
29. Parkinson, J. S. 1993. Signal transduction schemes of bacteria. Cell 73:857-871.
30. Perego, M., and J. A. Hoch. 1996. Cell-cell communication regulates the effects of protein aspartate phosphatases on the phosphorelay controlling development in Bacillus subtilis. Proc. Natl. Acad. Sci. USA 93:1549-1553.
31. Rida, S., J. Caillet, and J. H. Alix. 1996. Amplification of a novel gene, sanA, abolishes a vancomycin-sensitive defect in Escherichia coli. J. Bacteriol. 178: 94-102.
32. Rudolph, J., N. Tolliday, C. Schmitt, S. C. Schuster, and D. Oesterhelt. 1995. Phosphorylation in halobacterial signal transduction. EMBO J. 14:4249-4257.
33. Russel, M. 1994. Mutants at conserved positions in gene IV, a gene required for assembly and secretion of filamentous phages. Mol. Microbiol. 14:355-369.
34. Sambrook, J., E. F. Fritsch, and T. Maniatis. 1989. Molecular cloning: a laboratory manual, vol. 1, 2, and 3. Cold Spring Harbor Laboratory, Cold Spring Harbor, N.Y.
35. Sanna, M. G., R. V. Swanson, R. B. Bourret, and M. I. Simon. 1995. Mutations in the chemotactic response regulator, CheY, that confer resistance to the phosphatase activity of CheZ. Mol. Microbiol. 15:1069-1079.
36. Simons, R. W., F. Houman, and N. Kleckner. 1987. Improved single and multicopy lac-based cloning vectors for protein and operon fusions. Gene 53:85-96.
37. Skarphol, K., J. Waukau, and S. A. Forst. 1997. Role of His243 in the phosphatase activity of EnvZ in Escherichia coli. J. Bacteriol. 179:1413-1416.
38. Stewart, V., and R. S. Rabin. 1995. Dual sensors and dual response regulators interact to control nitrate- and nitrite-responsive gene expression in Escherichia coli, p. 233-252. In J. A. Hoch and T. J. Silhavy (ed.), Two-component signal transaction. American Society for Microbiology, Washington, D.C.
39. Swanson, R. V., L. A. Alex, and M. I. Simon. 1994. Histidine and aspartate phosphorylation: two-component systems and the limits of homology. Trends Biochem. Sci. 19:485-490.
40. Swartz, M. N. 1994. Hospital-acquired infections: diseases with increasingly limited therapies. Proc. Natl. Acad. Sci. USA 91:2420-2427.
41. Ulijasz, A. T., A. Grenader, and B. Weisblum. 1996. A vancomycin-inducible LacZ reporter system in Bacillus subtilis: induction by antibiotics that inhibit cell wall synthesis and by lysozyme. J. Bacteriol. 178:6305-6309.
42. Wandersman, C., and S. Létoffé. 1993. Involvement of lipopolysaccharide in the secretion of Escherichia coli α-haemolysin and Erwinia chrysanthemi proteases. Mol. Microbiol. 7:141-150.
43. Wanner, B. L. 1992. Is cross regulation by phosphorylation of two-component response regulator proteins important in bacteria? J. Bacteriol. 174: 2053-2058.
44. Wanner, B. L. 1994. Gene expression in bacteria using TnphoA and TnphoA' elements to make and switch phoA gene, lacZ (op), and lacZ (pr) fusions, p. 291-310. In K. W. Adolph (ed.), Methods in molecular genetics, vol. 3. Academic Press, Orlando, Fla.
45. Wanner, B. L. 1996. Phosphorus assimilation and control of the phosphate regulon, p. 1357-1381. In F. C. Neidhardt, R. Curtiss III, J. L. Ingraham, E. C. C. Lin, K. B. Low, Jr., B. Magasanik, W. S. Reznikoff, M. Riley, M. Schaechter, and H. E. Umbarger (ed.), Escherichia coli and Salmonella: cellular and molecular biology. ASM Press, Washington, D.C.
46. Wanner, B. L., and J. A. Boline. 1990. Mapping and molecular cloning of the phn (psiD) locus for phosphorate utilization in Escherichia coli. J. Bacteriol. 172:1186-1196.
47. Wanner, B. L., and B.-D. Chang. 1987. The phoBR operon in Escherichia coli K-12. J. Bacteriol. 169:5569-5574.
48. Wanner, B. L., W. Jiang, S.-K. Kim, S. Yamagata, A. Haldimann, and L. L. Daniels. 1996. Are the multiple signal transduction pathways of the Pho regulon due to cross talk or cross regulation?, p. 297-315. In E. C. C. Lin and A. S. Lynch (ed.), Regulation of gene expression in Escherichia coli. R. G. Landes Co., Austin, Tex.
49. Wanner, B. L., and M. R. Wilmes-Riesenberg. 1992. Involvement of phosphotransacetylase, acetate kinase, and acetyl phosphate synthesis in the control of the phosphate regulon in Escherichia coli. J. Bacteriol. 174:2124-2130.
50. Wilheim, M. P. 1991. Vancomycin. Mayo Clin. Proc. 66:1165-1170.
51. Wilmes-Riesenberg, M. R., and B. L. Wanner. 1992. TnphoA and TnphoA' elements for making and switching fusions for study of transcription, translation and cell surface localization. J. Bacteriol. 174:4558-4575.
52. Wright, G. D., T. R. Holman, and C. T. Walsh. 1993. Purification and characterization of VanR and the cytosolic domain of VanS: a two-component regulatory system required for vancomycin resistance in Enterococcus faecium BM4147. Biochemistry 32:5057-5063.
53. Wright, G. D., and C. T. Walsh. 1992. D-Alanyl-D-alanine ligases and the molecular mechanism of vancomycin resistance. Acc. Chem. Res. 25:468-473.
54. Yang, Y., and M. Inouye. 1993. Requirement of both kinase and phosphatase activities of an Escherichia coli receptor (Taz1) for ligand-dependent signal transduction. J. Mol. Biol. 231:335-342.