Methods for detecting apoptotic cells in tissues

Histology and Histopathology

Volumn 12, Issue 4, 1997, Pages 1169-1177

  Sanders, E J ^a  

^a UNIVERSITY OF ALBERTA   (Canada)

Author keywords

Apoptosis; Cell death; Methods; Review

Indexed keywords

APOPTOSIS; CELL DEATH; CELL LABELING; DNA STRAND BREAKAGE; FLOW CYTOMETRY; GENE EXPRESSION; IMMUNOCYTOCHEMISTRY; NECROSIS; REVIEW;

ANIMALS; APOPTOSIS; CELL PHYSIOLOGY; DNA; HISTOCYTOCHEMISTRY; HUMANS;

EID: 0030771250     PISSN: 02133911     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Review

References (15)

1. Abrams J.M., White K., Fessler L.I. and Steller H. (1993). Programmed cell death during Drosophila embryogenesis. Development 117, 29-43.
2. Ansari B., Coates P.J., Greenstein B.D. and Hall P.A. (1993). In situ end-labelling detects DNA strand breaks in apoptosis and other physiological and pathological states. J. Pathol. 170, 108.
3. Aschoff A., Jantz M. and Jirikowski G.F. (1996). In-situ end labelling with bromodeoxyuridine - an advanced technique for the visualization of apoptotic cells in histological specimens. Horm. Metab. Res. 28, 311-314.
4. Bellairs R. (1961). Cell death in chick embryos as studied by electron microscopy. J. Anat. 95, 54-63.
5. Bortner C.D., Oldenburg N.B.E. and Cidlowski J.A. (1995). The role of DNA fragmentation in apoptosis. Trends Cell Biol. 5, 21-26.
6. Bowen I.D. (1981). Techniques for demonstrating cell death. In: Cell death in biology and pathology. Bowen I.D. and Lockshin R.A. (eds.). Chapman and Hall. New York, pp 379-44.
7. Bromidge T.J., Howe D.J., Johnson S.A. and Phillips M.J. (1995). Adaptation of the TdT assay for semi-quantitative flow cytometric detection of DNA strand breaks. Cytometry 20, 257-260.
8. Camby I., Salmon I., Danguy A., Pasteels J-L. and Kiss R. (1995). The use of the digital cell image analysis of Feulgen-stained nuclei to detect apoptosis. Histochem. Cell Biol. 104, 407-414.
9. Cervós-Navarro J. and Schubert Th.E.O. (1996). Pitfalls in the evaluation of apoptosis using TUNEL. Brain Pathol. 6, 347-348.
10. Chaudun E., Arruti C., Courtois Y., Ferrag F., Jeanny J.C., Patel B.N., Skidmore C., Torriglia A. and Counis M.F. (1994). DNA strand breakage during physiological apoptosis of the embryonic chick lens: free 3'OH end single strand breaks do not accumulate even in the presence of a cation-independent deoxyribonuclease. J. Cell. Physiol. 158, 354-364.
11. Wyllie A.H. (1981). Cell death: a new classification separating apoptosis from necrosis. In: Cell death in biology and pathology. Bowen I.D. and Lockshin R.A. (eds). Chapman and Hall. New York, pp 9-34.
12. Wyllie A.H. (1992). Apoptosis and the regulation of cell numbers in normal and neoplastic tissues; an overview. Cancer Metast. Rev. 11, 95-103.
13. Wyllie A.H. (1995). The genetic regulation of apoptosis. Curr. Opin. Gen. Dev. 5, 97-104.
14. Yamada T. and Hata J. (1995). Simple and rapid method for detection of apoptotic cells by flow cytometry. Acta Histochem. Cytochem. 28, 277-280.
15. Zakeri Z.F., Quaglino D., Latham T. and Lockshin R.A. (1993). Delayed internucleosomal DMA fragmentation in programmed cell death. FASEB J. 7, 470-478.