Role of Syk in Fcγ receptor-coupled tyrosine phosphorylation of Cbl in a manner susceptible to inhibition by protein kinase C

European Journal of Immunology

Volumn 29, Issue 10, 1999, Pages 3302-3312

  Hazeki, Kaoru ^a   Hazeki, Osamu ^b   Matsuo, Tsuyoshi ^a   Seya, Tsukasa ^c   Yamashita, Toshiyuki ^d   Nagasawa, Shigeharu ^d   Band, Hamid ^f   Ui, Michio ^a,e  

^a INST OF PHYS AND CHEMICAL RESEARCH   (Japan)

^b HIROSHIMA UNIV SCHOOL OF MEDICINE   (Japan)

^c CENTER FOR ADULT DISEASES   (Japan)

^d HOKKAIDO UNIVERSITY   (Japan)

^e TOKYO METROPOLITAN INSTITUTE OF MEDICAL SCIENCE   (Japan)

^f NONE

Author keywords

Cbl; Fc receptor; Protein kinase C; Syk; Tyrosine phosphorylation

Indexed keywords

FC RECEPTOR; IMMUNOGLOBULIN RECEPTOR; ONCOPROTEIN; PHORBOL 13 ACETATE 12 MYRISTATE; PHOSPHORUS 32; PROTEIN KINASE C; PROTEIN TYROSINE KINASE; SERINE;

ANIMAL CELL; ANIMAL EXPERIMENT; ARTICLE; CONTROLLED STUDY; ENZYME ACTIVATION; ENZYME ASSAY; GUINEA PIG; IMMUNOPRECIPITATION; NEUTROPHIL; NONHUMAN; PRIORITY JOURNAL; PROTEIN PHOSPHORYLATION; PROTO ONCOGENE; SIGNAL TRANSDUCTION;

1-PHOSPHATIDYLINOSITOL 3-KINASE; ANIMALS; ENZYME PRECURSORS; GUINEA PIGS; INTRACELLULAR SIGNALING PEPTIDES AND PROTEINS; PHOSPHORYLATION; PRECIPITIN TESTS; PROTEIN KINASE C; PROTEIN-TYROSINE KINASES; PROTO-ONCOGENE PROTEINS; PROTO-ONCOGENE PROTEINS C-CBL; RECEPTOR PROTEIN-TYROSINE KINASES; RECEPTORS, IGG; SERINE; TETRADECANOYLPHORBOL ACETATE; UBIQUITIN-PROTEIN LIGASES;

EID: 0032864064     PISSN: 00142980     EISSN: None     Source Type: Journal    
DOI: 10.1002/(SICI)1521-4141(199910)29:10<3302::AID-IMMU3302>3.0.CO;2-G     Document Type: Article

References (43)

1. Miyake, S., Lupher, M. L., Jr., Andoniou, C. E., Lill, N. L., Ota, S., Douillard, P., Rao, N. and Band, H., The Cbl protooncogene product: from an enigmatic oncogene to center stage of signal transduction. Crit. Rev. Oncog. 1997. 8: 189-218.
2. Smit, L. and Borst, J., The Cbl family of signal transduction molecules. Crit. Rev. Oncog. 1997. 8: 359-379.
3. Liu, Y. C. and Altman, A., Cbl: complex formation and functional implications. Cell. Signal. 1998. 10: 377-385.
4. Lupher, M. L., Jr., Andoniou, C. E., Bonita, D., Miyake, S. and Band, H., The c-Cbl oncoprotein. Int. J. Biochem. Cell. Biol. 1998. 30: 439-444.
5. Ninomiya, N., Hazeki, K., Fukui, Y., Seya, T., Okada, T., Hazeki, O. and Ui, M., Involvement of phosphatidylinositol 3-kinase in Fc gamma receptor signaling. J. Biol. Chem. 1994. 269: 22732-22737.
6. Matsuo, T., Hazeki, K., Hazeki, O., Katada, T. and Ui, M., Specific association of phosphatidylinositol 3-kinase with the protooncogene product Cbl in Fc gamma receptor signaling. FEBS Lett. 1996. 382: 11-14.
7. Ui, M., Okada, T., Hazeki, K. and Hazeki, O., Wortmannin as a unique probe for an intracellular signalling protein, phosphoinositide 3-kinase. Trends Biochem. Sci. 1995. 20: 303-307.
8. Toullec, D., Pianetti, P., Coste, H. et al., The bisindolyl-maleimide GF 109203X is a potent and selective inhibitor of protein kinase C. J. Biol. Chem. 1991. 266: 15771-15781.
9. Shimamura, T., Nakamura, T. and Koyama, J., Analysis of Fc receptors for IgG on guinea pig peritoneal macrophages by the use of a monoclonal antibody to one of the Fc receptors. J. Biochem. 1986. 99: 227-235.
10. Sato, M. and Koyama, J., Characterization of the Fc receptor for IgG2 on guinea pig polymorphonuclear leukocytes by the use of a monoclonal antibody. J. Biochem. 1990. 108: 66-71.
11. Shimamura, T., Nakamura, T. and Koyama, J., Demonstration of the existence of two distinct Fc receptors for IgG isotypes on guinea-pig macrophages by the use of monoclonal antibodies. Mol. Immunol. 1987. 24: 67-74.
12. Crowley, M. T., Costello, P. S., Fitzer-Attas, C. J., Turner, M., Meng, F., Lowell, C., Tybulewicz, V. L. and DeFranco, A. L., A critical role for Syk in signal transduction and phagocytosis mediated by Fcgamma receptors on macrophages. J. Exp. Med. 1997. 186: 1027-1039.
13. Park, R. K., Kyono, W. T., Liu, Y. and Durden, D. L., CBL-GRB2 interaction in myeloid immunoreceptor tyrosine activation motif signaling. J. Immunol. 1998. 160: 5018-5027.
14. Tanaka, S., Neff, L., Baron, R. and Levy, J. B., Tyrosine phosphorylation and translocation of the c-cbl protein after activation of tyrosine kinase signaling pathways. J. Biol. Chem. 1995. 270: 14347-14351.
15. Izadi, K. D., Erdreich-Epstein, A., Liu, Y. B. and Durden, D. L., Characterization of Cbl-Nck and Nck-Pak1 interactions in myeloid FcgammaRII signaling. Exp. Cell Res. 1998. 245: 330-342.
16. cbl. J. Biol. Chem. 1999. 274: 1898-1904.
17. Deckert, M., Elly, C., Altman, A. and Liu, Y. C., Coordinated regulation of the tyrosine phosphorylation of Cbl by Fyn and Syk tyrosine kinases. J. Biol. Chem. 1998. 273: 8867-8874.
18. Feshchenko, E. A., Langdon, W. Y. and Tsygankov, A. Y., Fyn, Yes, and Syk phosphorylation sites in c-Cbl map to the same tyrosine residues that become phosphorylated in activated T cells. J. Biol. Chem. 1998. 273: 8323-8331.
19. Murphy, M. A., Schnall, R. G., Venter, D. J., Barnett, L., Bertoncello, I., Thien, C. B., Langdon, W. Y. and Bowtell, D. D., Tissue hyperplasia and enhanced T-cell signalling via ZAP-70 in c-Cbl-deficient mice. Mol. Cell. Biol. 1998. 18: 4872-4882.
20. Murray, E. W. and Robbins, S. M., Antibody cross-linking of the glycosyl-phosphatidylinositol-linked protein CD59 on hematopoietic cells induces signaling pathways resembling activation by complement. J. Biol. Chem. 1998. 273: 25279-25284.
21. Umehara, H., Huang, J. Y., Kono, T., Tabassam, F. H., Okazaki, T., Gouda, S., Nagano, Y., Bloom, E. T. and Domae, N., Co-stimulation of T cells with CD2 augments TCR-CD3-mediated activation of protein tyrosine kinase p72syk, resulting in increased tyrosine phosphorylation of adapter proteins, Shc and Cbl. Int. Immunol. 1998. 10: 833-845.
22. Lupher, M. L., Jr., Rao, N., Lill, N. L., Andoniou, C. E., Miyake, S., Clark, E. A., Druker, B. and Band, H., Cbl-mediated negative regulation of the Syk tyrosine kinase - A critical role for Cbl phosphotyrosine-binding domain binding to Syk phosphotyrosine 323. J. Biol. Chem. 1998. 273: 35273-35281.
23. Liu, Y. C., Liu, Y., Elly, C., Yoshida, H., Lipkowitz, S. and Altman, A., Serine phosphorylation of Cbl induced by phorbol ester enhances its association with 14-3-3 proteins in T cells via a novel serine-rich 14-3-3-binding motif. J. Biol. Chem. 1997. 272: 9979-9985.
24. Melendez, A., Floto, R. A., Cameron, A. J., Gillooly, D. J., Harnett, M. M. and Allen, J. M., A molecular switch changes the signalling pathway used by the Fc gamma RI antibody receptor to mobilize calcium. Curr. Biol. 1998. 8: 210-221.
25. Gratacap, M. P., Payrastre, B., Viala, C., Mauco, G., Plantavid, M. and Chap, H., Phosphatidylinositol 3,4,5-trisphosphate-dependent stimulation of phospholipase C-gamma2 is an early key event in FcgammaRIIA-mediated activation of human platelets. J. Biol. Chem. 1998. 273: 24314-24321.
26. 2+ levels in human neutrophils by soluble immune complexes. Functional activation of FcgammaRIIIb during priming. J. Biol. Chem. 1997. 272: 17944-17951.
27. Melendez, A., Floto, R. A., Gillooly, D. J., Harnett, M. M. and Allen, J. M., FcgammaRI coupling to phospholipase D initiates sphingosine kinase-mediated calcium mobilization and vesicular trafficking. J. Biol. Chem. 1998. 273: 9393-9402.
28. Hunter, T. and Sefton, B. M., Transforming gene product of Rous sarcoma virus phosphorylates tyrosine. Proc. Natl. Acad. Sci. USA 1980. 77: 1311-1315.
29. Bossenmaier, B., Mosthaf, L., Mischak, H., Ullrich, A. and Haring, H. U., Protein kinase C isoforms beta 1 and beta 2 inhibit the tyrosine kinase activity of the insulin receptor. Diabetologia 1997. 40: 863-866.
30. Haring, H. U., Tippmer, S., Kellerer, M., Mosthaf, L., Kroder, G., Bossenmaier, B. and Berti, L., Modulation of insulin receptor signaling. Potential mechanisms of a cross talk between bradykinin and the insulin receptor. Diabetes 1996. 45: S115-119.
31. Mogi, A., Hatai, M., Soga, H., Takenoshita, S., Nagamachi, Y., Fujimoto, J., Yamamoto, T., Yokota, J. and Yaoi, Y., Possible role of protein kinase C in the regulation of intracellular stability of focal adhesion kinase in mouse 3T3 cells. FEBS Lett. 1995. 373: 135-140.
32. Song, J. S., Swann, P. G., Szallasi, Z., Blank, U., Blumberg, P. M. and Rivera, J., Tyrosine phosphorylation-dependent and -independent associations of protein kinase C-delta with Src family kinases in the RBL-2H3 mast cell line: regulation of Src family kinase activity by protein kinase C-delta. Oncogene 1998. 16: 3357-3368.
33. De Fea, K. and Roth, R. A., Modulation of insulin receptor substrate-1 tyrosine phosphorylation and function by mitogen-activated protein kinase. J. Biol. Chem. 1997. 272: 31400-31406.
34. De Fea, K. and Roth, R. A., Protein kinase C modulation of insulin receptor substrate-1 tyrosine phosphorylation requires serine 612. Biochemistry 1997. 36: 12939-12947.
35. Mothe, I. and van Obberghen, E., Phosphorylation of insulin receptor substrate-1 on multiple serine residues, 612, 632, 662 and 731, modulates insulin action. J. Biol. Chem. 1996. 271: 11222-11227.
36. Folli, F., Kahn, C. R., Hansen, H., Bouchie, J. L. and Feener, E. P., Angiotensin II inhibits insulin signaling in aortic smooth muscle cells at multiple levels. A potential role for serine phosphorylation in insulin/angiotensin II crosstalk. J. Clin. Invest. 1997. 100: 2158-2169.
37. Kanety, H., Feinstein, R., Papa, M. Z., Hemi, R. and Karasik, A., Tumor necrosis factor alpha-induced phosphorylation of insulin receptor substrate-1 (IRS-1). Possible mechanism for suppression of insulin-stimulated tyrosine phosporylation of IRS-1. J. Biol. Chem. 1995. 270: 23780-23784.
38. Paz, K., Hemi, R., LeRoith, D., Karasik, A., Elhanany, E., Kanety, H. and Zick, Y., A molecular basis for insulin resistance. Elevated serine/threonine phosphorylation of IRS-1 and IRS-2 inhibits their binding to the juxtamembrane region of the insulin receptor and impairs their ability to undergo insulin-induced tyrosine phosphorylation. J. Biol. Chem. 1997. 272: 29911-29918.
39. Ricort, J. M., Tanti, J. F., van Obberghen, E. and Le Marchand-Brustel, Y., Cross-talk between the platelet-derived growth factor and the insulin signaling pathways in 3T3-L1 adipocytes. J. Biol. Chem. 1997. 272: 19814-19818.
40. Tanti, J. F., Gremeaux, T., van Obberghen, E. and Le Marchand-Brustel, Y., Serine/threonine phosphorylation of insulin receptor substrate 1 modulates insulin receptor signaling. J. Biol. Chem. 1994. 269: 6051-6057.
41. Thien, C. B. F. and Langdon, W. Y., c-Cbl: A regulator of T cell receptor-mediated signalling. Immunol. Cell. Biol. 1998. 76: 473-482.
42. Seya, T. and Nagasawa, S., Isolation of an iC3b forming enzyme from peritoneal polymorphonuclear leukocytes of guinea pigs. Biochem. Biophys. Res. Commun. 1983. 117: 413-419.
43. Coopper, J. A., Sefton, B. M. and Hunter, T., Detection and quantification of phosphotyrosine in proteins. Methods Enzymol. 1983. 99: 387-402.