A viral activator of gene expression functions via the ubiquitin-proteasome pathway

EMBO Journal

Volumn 17, Issue 24, 1998, Pages 7161-7169

  Everett, Roger D ^a   Orr, Anne ^a   Preston, Chris M ^a  

^a INSTITUTE OF VIROLOGY   (United Kingdom)

Author keywords

HSV 1; Latency; Ubiquitin proteasome pathway; Vmw110

Indexed keywords

IMMEDIATE EARLY PROTEIN; PROTEASOME; UBIQUITIN;

ANIMAL CELL; ARTICLE; CONTROLLED STUDY; GENE EXPRESSION REGULATION; HERPES SIMPLEX VIRUS 1; LATENT VIRUS INFECTION; NONHUMAN; PRIORITY JOURNAL; PROTEIN STABILITY; SENSORY NERVE; VIRUS REPLICATION;

CYSTEINE ENDOPEPTIDASES; CYSTEINE PROTEINASE INHIBITORS; GENE EXPRESSION REGULATION, VIRAL; HERPESVIRUS 1, HUMAN; IMMEDIATE-EARLY PROTEINS; LEUPEPTINS; MULTIENZYME COMPLEXES; NEOPLASM PROTEINS; NUCLEAR PROTEINS; PROTEASOME ENDOPEPTIDASE COMPLEX; PROTEIN ISOFORMS; TRANSCRIPTION FACTORS; TUMOR SUPPRESSOR PROTEINS; UBIQUITIN-PROTEIN LIGASES; UBIQUITINS; VIRUS ACTIVATION; VIRUS LATENCY; VIRUS REPLICATION;

ANIMALIA; DNA VIRUSES; HERPES; HUMAN HERPESVIRUS 1;

EID: 0032534802     PISSN: 02614189     EISSN: None     Source Type: Journal    
DOI: 10.1093/emboj/17.24.7161     Document Type: Article

References (18)

1. Ace,C.I., McKee,T., Ryan,J.M., Cameron,J.M. and Preston,C.M. (1989) Construction and characterisation of a herpes simplex virus type 1 mutant unable to transinduce immediate-early gene expression. J. Virol., 63, 2260-2269.
2. Ahn,J.-H. and Hayward,G.S. (1997) The major immediate early proteins IE1 and IE2 of human cytomegalovirus colocalise with and disrupt PML-associated nuclear bodies at very early times in infected permissive cells. J. Virol., 71, 4599-4613.
3. Alcalay,M., Tomassoni,L., Colombo,E., Stoldt,S., Grignani,F., Fagioli,M., Szekely,L., Helin,K. and Pelicci,P.G. (1998) The promyleocytic leukaemia gene product (PML) forms stable complexes with the retinoblastoma protein. Mol. Cell. Biol., 18, 1084-1093.
4. Cai,W., Astor,T.D., Liptak,L.M., Cho,C., Coen,D. and Schaffer,P.A. (1993) The herpes simplex virus type 1 regulatory protein ICP0 enhances replication during acute infection and reactivation from latency. J. Virol., 67, 7501-7512.
5. Carvalho,T., Seeler,J.-S., Ohman,K., Jordan,P., Petterson,U., Akusjarvi,G., Carmo-Fonseca,M. and Dejean,A. (1995) Targeting of adenovirus E1A and E4-orf3 proteins to nuclear matrix-associated PML bodies. J. Cell Biol., 131, 45-56.
6. Doucas,V., Ishov,A., Romo,A., Juguilon,H., Weitzman,M.D., Evans,R.M. and Maul,G.G. (1996) Adenovirus replication is coupled with the dynamic properties of the PML nuclear structure. Genes Dev., 10, 196-207.
7. Dyck,J.A., Maul,G.G., Miller,W.H.,Jr, Chen,J.D., Kakizuka,A. and Evans,R.M. (1994) A novel macromolecular structure is a target of the promyelocytic-retinoic acid receptor oncoprotein. Cell, 76, 333-343.
8. Everett,R.D. (1989) Construction and characterisation of herpes simplex virus type 1 mutants with defined lesions in immediate-early gene 1. J. Gen. Virol., 70, 1185-1202.
9. Everett,R.D. and Maul,G.G. (1994) HSV-1 IE protein Vmw110 causes redistribution of PML. EMBO J., 13, 5062-5069.
10. Everett,R.D., Preston,C.M. and Stow,N.D. (1991) Functional and genetic analysis of the role of Vmw110 in herpes simplex virus replication. In Wagner,E.K. (ed.), The Control of Herpes Simplex Virus Gene Expression. CRC Press Inc., Boca Raton, FL, pp. 50-76.
11. Everett,R.D., Cross,A. and Orr,A. (1993a) A truncated form of herpes simplex virus type 1 immediate-early protein Vmw110 is expressed in a cell type dependent manner Virology, 197, 751-756.
12. Everett,R.D., Cross,A., Tyler,J.K. and Orr,A. (1993b) An epitope within the DNA binding domain of the herpes simplex virus immediate-early protein Vmw175 is conserved in the varicella-zoster virus gene 62 protein. J. Gen. Virol., 74, 1955-1958.
13. Everett,R.D., Meredith,M.R., Orr,A., Cross,A., Kathoria,M. and Parkinson,J. (1997) A novel ubiquitin-specific protease is dynamically associated with the PML nuclear domain and binds to a herpesvirus regulatory protein. EMBO J., 16, 1519-1530.
14. Everett,R.D., Freemont,P., Saitoh,H., Dasso,M., Orr,A., Kathoria,M. and Parkinson,J. (1998) The disruption of ND10 during herpes simplex virus infection correlates with the Vmw110 and proteasome-dependent loss of several PML isoforms. J. Virol., 72, 6581-6591.
15. Fields,B.N., Knipe,D.M. and Howley,P.M. (eds) (1996) Virology, 3rd edn, Vol. 2. Lippincott-Raven, Philadelphia, PA.
16. Fraser,N.W., Block,T.M. and Spivack,J.G. (1992) The latency associated transcripts of herpes simplex virus: RNA in search of a function. Virology, 191, 1-8.
17. Henchoz,S., De Rubertis,F., Pauli,D. and Spierer,P. (1996) The dose of a putative ubiquitin-specific protease affects position-effect variegation in Drosophila melanogaster. Mol. Cell. Biol., 16, 5717-5725.
18. Ishov,A.M. and Maul,G.G. (1996) The periphery of nuclear domain 10 (ND10) as site of DNA virus deposition. J. Cell. Biol., 134, 815-826.