The herpes simplex virus type 1 immediate-early protein ICP0 is necessary for the efficient establishment of latent infection

Journal of Virology

Volumn 71, Issue 9, 1997, Pages 6777-6785

  Wilcox, C L ^a   Smith, R L ^b   Everett, R D ^c   Mysofski, D ^a  

^a Immunology and Pathology   (United States)

^b UNIVERSITY OF COLORADO   (United States)

^c INSTITUTE OF VIROLOGY   (United Kingdom)

Author keywords

[No Author keywords available]

Indexed keywords

IMMEDIATE EARLY PROTEIN; NERVE GROWTH FACTOR; VIRUS DNA;

ANIMAL CELL; ARTICLE; CONTROLLED STUDY; DNA DETERMINATION; EMBRYO; HERPES SIMPLEX VIRUS 1; IMMUNOHISTOCHEMISTRY; IN SITU HYBRIDIZATION; LATENT VIRUS INFECTION; NONHUMAN; NORTHERN BLOTTING; PRIORITY JOURNAL; RAT; SPINAL GANGLION; VIRUS REACTIVATION; VIRUS REPLICATION;

EID: 0030796174     PISSN: 0022538X     EISSN: None     Source Type: Journal    
DOI: 10.1128/jvi.71.9.6777-6785.1997     Document Type: Article

References (45)

1. Cal, W., T. L. Astor, L. M. Liptak, C. Cho, D. M. Coen, and P. A. Schaffer. 1993. The herpes simplex virus type 1 regulatory protein ICP0 enhances virus replication during acute infection and reactivation from latency. J. Virol. 67:7501-7512.
2. Cai, W., and P. Schaffer. 1991. A cellular function can enhance gene expression and plating efficiency of a mutant defective in the gene for ICP0, a transactivating protein of herpes simplex virus type 1. J. Virol. 65:4078-4090.
3. Clements, G. B., and N. D. Stow. 1989. A herpes simplex virus type 1 mutant containing a deletion within immediate early gene 1 is latent-competent in mice. J. Gen. Virol. 70:2501-2506.
4. DeLuca, N. A., A. M. McArthy, and P. A. Schaffer. 1985. Isolation and characterization of deletion mutants of herpes simplex virus type 1 in the gene encoding immediate-early regulatory protein ICP4. J. Virol. 56:558-570.
5. Doerig, C., L. I. Pizer, and C. L. Wilcox. 1991. Detection of the latency-associated transcript on neuronal cultures during the latent infection with herpes simplex virus type 1. Virology 183:423-426.
6. Dyck, J. A., G. G. Maul, W. H. Miller, J. D. Chen, A. Kakizuka, and R. M. Evans. 1994. A novel macromolecular structure is a target of the promyelocytc-retinoic acid receptor oncoprotein. Cell 76:333-343.
7. Efstathiou, S., A. C. Minson, H. J. Field, J. R. Anderson, and P. Wildly. 1986. Detection of herpes simplex virus-specific DNA sequences in latently infected mice and in humans. J. Virol. 57:446-455.
8. Everett, R. D. 1988. Analysis of the functional domains of herpes simplex virus type 1 immediate-early polypeptide Vmw 110. J. Mol. Biol. 202:87-96.
9. Everett, R. D. 1989. Construction and characterization of herpes simplex virus type 1 mutants with defined lesions in immediate-early gene 1. J. Gen. Virol. 70:1185-1202.
10. Everett, R. D. 1984. Transactivation of transcription by a herpes simplex virus product: requirement of two HSV-1 immediate early polypeptides for maximal activity. EMBO J. 3:3135-3141.
11. Everett, R. D., and G. G. Maul. 1994. HSV-1 IE protein Vmw 110 causes redistribution of PML. EMBO J. 13:5062-5069.
12. Everett, R. D., P. O'Hare, D. O'Rourke, P. Barlow, and A. Orr. 1995. Point mutations in the herpes simplex virus type 1 Vmw 110 RING finger helix affect activation of gene expression, viral growth, and interaction with PML-containing nuclear structures. J. Virol. 69:7339-7344.
13. Everett, R. D., C. M. Preston, and N. D. Stow. 1991. Functional and genetic analysis of the role of Vmw 110 in herpes simplex virus replication, p. 50-76. In E. K. Wagner (ed.), The control of herpes simplex virus gene expression. CRC Press, Inc., Boca Raton, Fla.
14. Fraser, N. I., T. M. Block, and J. G. Spivack. 1992. The latency-associated transcripts of herpes simplex virus: RNA in search of a function. Virology 191:1-8.
15. Gelman, I. H., and S. Silverstein. 1985. Identification of immediate-early genes from herpes simplex virus that transactivate the virus thymidine kinase gene. Proc. Natl. Acad. Sci. USA 85:6347-6351.
16. Harris, R. A., R. D. Everett, X. Zhu, S. Silverstein, and C. M. Preston. 1989. Herpes simplex virus type 1 immediate-early protein Vmw 110 reactivates latent herpes simplex virus type 2 in an in vitro latency system. J. Virol. 63:3513-3515.
17. Leib, D. A., D. M. Coen, C. L. Bogard, K. A. Hicks, D. R. Yager, D. Knipe, K. L. Tyler, and P. A. Schaffer. 1989. Immediate early regulation gene mutants define different stages in the establishment, and reactivation of herpes simplex latency. J. Virol. 63:759-768.
18. Maul, G. G., and R. D. Everett. 1994. The nuclear location of PML, a cellular member of the C3HC4 zinc binding domain protein family, is rearranged during herpes simplex virus infection by the C3HC4 viral protein ICP0. J. Gen. Virol. 75:1223-1233.
19. Maul, G. G., H. H. Guldner, and J. G. Spivack. 1943. Modification of discrete nuclear domains induced by herpes simplex virus type 1 immediate early gene 1 product (ICP0). J. Gen. Virol. 74:2679-2690.
20. Maul, G. G., A. M. Ishov, and R. D. Everett. 1996. Nuclear domain 10 as preexisting potential replication start sites of herpes simplex virus type-1. Virology 217:67-75.
21. McGeoch, D. J. 1989. The genomes of the human herpesvirus: contents, relationships, evolution. Annu. Rev. Microhiol. 43:235-265.
22. McGeoch, D. J., M. A. Dalrymple, A. J. Davison, Y. Dolan, M. C. Frame, D. McNab, L. J. Perry, J. E. Scott, and P. Toylor. 1988. The complete DNA sequence of the long unique region in the genome of herpes simplex virus type 1. J. Gen. Virol. 69:1531-1574.
23. Mehta, A., J. Maggioncalda, O. Bagasra, S. Thikkavarapu, P. Saikumari, T. Valyi-Nagy, N. W. Fraser, and T. M. Block. 1995. In situ DNA PCR and RNA hybridization detection of herpes simplex virus sequences in trigeminal ganglia of latently infected mice. Virology 206:633-640.
24. Meredith, M., A. Orr, M. Elliott, and R. Everett. 1995. Separation of sequence requirements for HSV-1 Vmw 110 multimerisation and interaction with a 135-kDa protein. Virology 209:174-187.
25. Natarajan, R., S. Deshmane, T. Valyi-Nagy, R. Everett, and N. W. Fraser. 1991. A herpes simplex virus type 1 mutant lacking the ICP0 introns reactivates with normal efficiency. J. Virol. 65:5569-5573.
26. O'Hare, P., and G. S. Hayward. 1985. Evidence for a direct role for both the 175,000- and 110,000-molecular-weight immediate-early proteins of herpes simplex virus in the transactivation of delayed early promoters. J. Virol. 53:751-760.
27. Perbal, B. 1988. A practical guide to molecular cloning, 2nd ed. John Wiley & Sons, Inc., New York, N.Y.
28. Ramakrishnan, R., M. Levine, and D. J. Fink. 1994. PCR-based analysis of herpes simplex virus type 1 latency in the rat trigeminal ganglion established with a ribonucleotide reductasc-deficient mutant. J. Virol. 68:7083-7091.
29. Rock, D. L., and N. W. Fraser. 1983. Detection of HSV-1 genome in central nervous system of latently infected mice. Nature 302:523-525.
30. Sucks, W. R., and P. A. Schaffer. 1987. Deletion mutants in the gene encoding the herpes simplex virus type 1 immediate-early protein ICP0 exhibit impaired growth in cell culture. J. Virol. 61:829-839.
31. Sambrook, J., E. F. Fritsch, and T. Maniatis. 1989. Molecular cloning: a laboratory manual. Cold Spring Harbor Laboratory Press, Cold Spring Harbor, N.Y.
32. Schaack, J., S. Langer, and X. Guo. 1995. Efficient selection of recombinant adenoviruses by vectors that express β-galactosidase. J. Virol. 69:3920-3923.
33. Sedarati, F., T. Margolis, and J. Stevens. 1993. Latent infection can be established with drastically restricted transcription and replication of the HSV-1 genome. J. Virol. 192:687-691.
34. Simmon, A., B. Slobedman, P. Speck, J. Arthur, and S. Efstathious. 1992. Two patterns of persistence of herpes simplex virus DNA sequences in the nervous system of latently infected mice. J. Gen. Virol. 73:1287-1291.
35. Smith, R. L., J. L. Escudero, and C. L. Wilcox. 1994. Regulation of the herpes simplex virus latency-associated transcript during establishment of latency in sensory neurons in vitro. Virology 202:49-60.
36. Smith, R. L., A. I. Geller, K. W. Escudero, and C. L. Wilcox. 1995. Long-term expression in sensory neurons in tissue culture from HSV-1 promoters in herpes-derived vectors. J. Virol. 69:4593-4599.
37. Staley, K. J., R. L. Smith, J. Schaack, C. L. Wilcox, and T. Jentsch. 1996. Alteration of GABA-A receptor function following gene transfer of the ClC-2 chloride channel. Neuron 17:543-551.
38. Stow, N. D., and E. C. Stow. 1986. Isolation and characterization of a herpes simplex virus type 1 mutant containing a deletion within the gene encoding the immediate-early polypeptide Vmw 110. J. Gen. Virol. 67: 2571-2585.
39. Weis, K., S. Rambaud, C. Lavau, J. Jansen, T. Carvalho, M. Carmo-Fonseca, A. Lamond, and A. Dejean. 1994. Retinoic acid regulates aberrant nuclear localization of PML-RARα in acute promyelocyte leukemia cells. Cell 76:345-356.
40. Wilcox, C. L., and E. M. Johnson, Jr. 1988. Characterization of nerve growth factor-dependent herpes simplex virus latency in neurons in vitro. J. Virol. 62:393-399.
41. Wilcox, C. L., and E. M. Johnson. 1987. Nerve growth factor deprivation results in the reactivation of latent herpes simplex virus in vitro. J. Virol. 61:2311-2315.
42. Wilcox, C. L., R. L. Smith, C. Freed, and E. M. Johnson. 1990. Nerve growth factor-dependence of herpes simplex latency in peripherial sympathetic and sensory neurons in vitro. J. Neurosci. 10:1268-1275.
43. Yao, F., and R. J. Courtney. 1992. Association of ICP0 but not ICP27 with purified virions of herpes simplex virus type 1. J. Virol. 66:2709-2716.
44. Zhu, X., J. Chen, C. Young, and S. Silverstein. 1990. Reactivation of latent herpes simplex virus by adenovirus recombinants encoding mutant IE-0 gene products. J. Virol. 64:4489-4498.
45. Zhu, X., C. S. H. Young, and S. Silverstein. 1988. Adenovirus vector expressing functional herpes simplex virus ICP0. J. Virol. 62:4544-4553.