Residues in the seventh membrane-spanning segment of the dopamine D2 receptor accessible in the binding-site crevice

Biochemistry

Volumn 35, Issue 35, 1996, Pages 11278-11285

  Fu, Dingyi ^a   Ballesteros, Juan A ^b   Weinstein, Harel ^b   Chen, Jiayun ^a   Javitch, Jonathan A ^a  

^a Columbia University ^*  (United States)

^b MOUNT SINAI SCHOOL OF MEDICINE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

DOPAMINE 2 RECEPTOR; DOPAMINE RECEPTOR BLOCKING AGENT; SULPIRIDE;

ARTICLE; BINDING SITE; CONTROLLED STUDY; HUMAN; HUMAN CELL; MOLECULAR INTERACTION; PRIORITY JOURNAL; RECEPTOR BINDING; SITE DIRECTED MUTAGENESIS; STRUCTURE ACTIVITY RELATION;

AMINO ACID SEQUENCE; BINDING SITES; CELL LINE; CYSTEINE; DOPAMINE ANTAGONISTS; ETHYL METHANESULFONATE; GTP-BINDING PROTEINS; HUMANS; KINETICS; MEMBRANE PROTEINS; MODELS, MOLECULAR; MOLECULAR SEQUENCE DATA; MUTAGENESIS, SITE-DIRECTED; PROTEIN STRUCTURE, SECONDARY; PROTEIN STRUCTURE, TERTIARY; RECEPTORS, DOPAMINE D2; SIGNAL TRANSDUCTION; SPIPERONE; SULFHYDRYL REAGENTS; SULPIRIDE;

EID: 0029757635     PISSN: 00062960     EISSN: None     Source Type: Journal    
DOI: 10.1021/bi960928x     Document Type: Article

References (42)

1. Akabas, M. H., Stauffer, D. A., Xu, M., & Karlin, A. (1992) Science 258, 307-10.
2. Akabas, M. H., Kaufmann, C., Archdeacon, P., & Karlin, A. (1994) Neuron 13, 919-27.
3. Baldwin, J. M. (1993) EMBO J. 12, 1693-703.
4. Ballesteros, J. A., & Weinstein, H. (1992) Biophys. J. 62, 107-9.
5. Ballesteros, J. A., & Weinstein, H. (1995) Methods Neurosci. 25,366-428.
6. Barak, L. S., Menard, L., Ferguson, S. S., Colapietro, A. M., & Caron, M. G. (1995) Biochemistry 34, 15407-14.
7. Barlow, D. J., & Thornton, J. M. (1988) J. Mol. Biol. 201, 601-19.
8. Berlose, J. P., Convert, O., Brunissen, A., Chassaing, G., & Lavielle, S. (1994) Eur. J. Biochem. 225,827-43.
9. Civelli, O., Bunzow, J. R., Grandy, D. K., Zhou, Q. Y., & Van Tol, H. H. (1991) Eur. J. Pharmacol. 207, 277-86.
10. Donnelly, D., Johnson, M. S., Blundell, T. L., & Saunders, J. (1989) FEBS Lett. 251, 109-16.
11. Dougherty, D. A. (1996) Science 271, 163-8.
12. Findlay, J. B., & Pappin, D. J. (1986) Biochem. J. 238, 625-42.
13. Goldstein, A., & Barrett, R. W. (1987) Mol. Pharmacol. 31, 603-9.
14. Henderson, R., Baldwin, J. M., Ceska, T. A., Zemlin, F., Beckmann, E., & Downing, K. H. (1990) J. Mol. Biol. 213, 899-929.
15. Javitch, J. A., Li, X., Kaback, J., & Karlin, A. (1994) Proc. Natl. Acad. Sci. U.S.A. 91, 10355-9.
16. Javitch, J. A., Fu, D., Chen, J., & Karlin, A. (1995a) Neuron 14,825-31.
17. Javitch, J. A., Fu, D., & Chen, J. (1995b) Biochemistry 34, 16433-9.
18. Javitch, J. A., Fu, D., & Chen, J. (1996) Mol. Pharmacol. 49, 692-8.
19. Kozell, L. B., Machida, C. A., Neve, R. L., & Neve, K. A. (1994) J. Biol. Chem. 269, 30299-306.
20. Liu, J., Schoneberg, T., van Rhee, M., & Wess, J. (1995) J. Biol. Chem. 270, 19532-9.
21. Luo, X., Zhang, D., & Weinstein, H. (1994) Protein Eng. 7,1441-8.
22. MacKenzie, R. G., Steffey, M. E., Manelli, A. M., Pollock, N. J., & Frail, D. E. (1993) FEBS Lett. 323, 59-62.
23. Mizobe, T., Maze, M., Lam, V., Suryanarayana, S., & Kobilka, B. K. (1996) J. Biol. Chem. 271, 2387-9.
24. Oprian, D. D. (1992) J. Bioenerg. Biomembr. 24, 211-7.
25. Rees, D. C., Komiya, H., Yeates, T. O., Allen, J. P., & Feher, G. (1989) Annu. Rev. Biochem. 58, 607-33.
26. Roberts, D. D., Lewis, S. D., Ballou, D. P., Olson, S. T., & Shafer, J. A. (1986) Biochemistry 25, 5595-601.
27. Sankararamakrishnan, R., & Vishveshwara, S. (1992) Int. J. Pept. Protein Res. 39, 356-63.
28. Sansom, M. S. (1992) Protein Eng. 5, 53-60.
29. Schertier, G. F. X., & Hargrave, P. A. (1995) Proc. Natl. Acad. Sci. U.S.A. 92, 11578-82.
30. Schertler, G. F., Villa, C., & Henderson, R. (1993) Nature 362,770-2.
31. Sealfon, S. C., Chi, L., Ebersole, B. J., Rodic, V., Zhang, D., Ballesteros, J. A., & Weinstein, H. (1995) J. Biol. Chem. 270,16683-8.
32. Stauffer, D. A., & Karlin, A. (1994) Biochemistry 33, 6840-9.
33. Strader, C. D., Candelore, M. R., Hill, W. S., Sigal, I. S., & Dixon, R. A. (1989) J. Biol. Chem. 264, 13572-8.
34. Strader, C. D., Fong, T. M., Tota, M. R., Underwood, D., & Dixon, R. A. (1994) Annu. Rev. Biochem. 63, 101-32.
35. Suryanarayana, S., Daunt, D. A., Von, Z. M., & Kobilka, B. K. (I991) J. Biol. Chem. 266, 15488-92.
36. Teeter, M. M., & DuRand, C. J. (1996) Drug Dev. Res. (in press).
37. van Rhee, A. M., & Jacobson, K. A. (1996) Drug Dev. Res. 37,1-38.
38. Williams, K. A., & Deber, C. M. (1991) Biochemistry 30, 8919-23.
39. Wong, S. K., Slaughter, C., Ruoho, A. E., & Ross, E. M. (1988) J. Biol. Chem. 263, 7925-8.
40. Woolfson, D. N., Mortishire, S. R. J., & Williams, D. H. (1991) Biochem. Biophys. Res. Commun. 175, 733-7.
41. Zhang, D., & Weinstein, H. (1993) J. Med. Chem. 36, 934-8.
42. Zhou, W., Flanagan, C., Ballesteros, J. A., Konvicka, K., Davidson, J. S., Weinstein, H., Millar, R. P., & Sealfon, S. C. (1994) Mol. Pharmacol. 45, 165-70.