A biomarker that identifies senescent human cells in culture and in aging skin in vivo

Proceedings of the National Academy of Sciences of the United States of America

Volumn 92, Issue 20, 1995, Pages 9363-9367

  Dimri, Goberdhan P ^a   Lee, Xinhua ^b   Basile, George ^a   Acosta, Meileen ^a   Scott, Glynis ^c   Roskelley, Calvin ^a   Medrano, Estela E ^d   Linskens, Maarten ^e   Rubelj, Ivica ^d   Pereira Smith, Olivia ^d   Peacocke, Monica ^b   Campisi, Judith ^a  

^a UNIVERSITY OF CALIFORNIA   (United States)

^b TUFTS UNIVERSITY SCHOOL OF MEDICINE   (United States)

^c UNIVERSITY OF ROCHESTER SCHOOL OF MEDICINE AND DENTISTRY   (United States)

^d BAYLOR COLLEGE OF MEDICINE   (United States)

^e GERON CORPORATION   (United States)

Author keywords

galactosidase; replicative senescence; tumor suppression

Indexed keywords

BETA GALACTOSIDASE; BIOLOGICAL MARKER;

ARTICLE; CELL DIVISION; CELL PROLIFERATION; CELL VIABILITY; FIBROBLAST; GENETIC MANIPULATION; HUMAN; HUMAN CELL; HUMAN TISSUE; KERATINOCYTE; LIFESPAN; PRIORITY JOURNAL; SENESCENCE; SKIN CULTURE; TUMOR SUPPRESSOR GENE;

ADULT; AGED; AGED, 80 AND OVER; BETA-GALACTOSIDASE; BIOLOGICAL MARKERS; CELL AGING; CELL DIFFERENTIATION; CELL DIVISION; CELL LINE; CELL TRANSFORMATION, NEOPLASTIC; CELLS, CULTURED; COMPARATIVE STUDY; DNA; EPIDERMIS; FEMALE; FIBROBLASTS; HELA CELLS; HUMAN; KERATINOCYTES; MALE; SKIN; SKIN AGING; SKIN NEOPLASMS; SUPPORT, U.S. GOV'T, P.H.S.; THYMIDINE;

EID: 0029047362     PISSN: 00278424     EISSN: None     Source Type: Journal    
DOI: 10.1073/pnas.92.20.9363     Document Type: Article

References (31)