Mutation of individual serine residues in the C-terminal tail of the lutropin/choriogonadotropin receptor reveal distinct structural requirements for agonist-induced uncoupling and agonist-induced internalization

Journal of Biological Chemistry

Volumn 273, Issue 29, 1998, Pages 18316-18324

  Lazari, Maria De Fatima M ^a   Bertrand, Jennifer E ^a   Nakamura, Kazuto ^a   Liu, Xuebo ^a   Krupnick, Jason G ^b   Benovic, Jeffrey L ^b,c   Ascoli, Mario ^a  

^a UNIVERSITY OF IOWA   (United States)

^b THOMAS JEFFERSON UNIVERSITY   (United States)

^c AMERICAN HEART ASSOCIATION   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ALANINE; CHORIONIC GONADOTROPIN; CHORIONIC GONADOTROPIN RECEPTOR; CYCLIC AMP; DYNAMIN; LUTEINIZING HORMONE; LUTEINIZING HORMONE RECEPTOR; RETINA S ANTIGEN; SERINE;

ARTICLE; CARBOXY TERMINAL SEQUENCE; CONTROLLED STUDY; EMBRYO; ENDOCYTOSIS; HUMAN; HUMAN CELL; IMMUNOBLOTTING; IMMUNOPRECIPITATION; INTERNALIZATION; MUTATION; PHOSPHORYLATION; PRIORITY JOURNAL; SIGNAL TRANSDUCTION;

EID: 0032541044     PISSN: 00219258     EISSN: None     Source Type: Journal    
DOI: 10.1074/jbc.273.29.18316     Document Type: Article

References (42)

1. Premont, R. T., Inglese, J., and Lefkowitz, R. J. (1995) FASEB J. 9, 175-182
2. Hausdorff, W. P., Caron, M. G., and Lefkowitz, R. J. (1990) FASEB J. 4, 2881-2889
3. Goodman, J. O. B., Krupnick, J. G., Santini, F., Gurevich, V. V., Penn, R. B., Gagnon, A. W., Keen, J. H., and Benovic, J. L. (1996) Nature 383, 447-450
4. Krupnick, J. G., Santini, F., Gagnon, A. W., Keen, J. H., and Benovic, J. L. (1997) J. Biol. Chem. 272, 32507-32512
5. Hipkin, R. W., Sánchez-Yagüe, J., and Ascoli, M. (1993) Mol. Endocrinol. 7, 823-832
6. Hipkin, R. W., Wang, Z., and Ascoli, M. (1995) Mol. Endocrinol. 9, 151-158
7. Premont, R. T., Macrae, A. D., Stoffel, R. H., Chung, N., Pitcher, J. A., Ambrose, C., Inglese, J., MacDonald, M. E., and Lefkowitz, R. J. (1996) J. Biol. Chem. 271, 6403-6410
8. Wang, Z., Hipkin, R. W., and Ascoli, M. (1996) Mol. Endocrinol. 10, 748-759
9. Wang, Z., Liu, X., and Ascoli, M. (1997) Mol. Endocrinol. 11, 183-192
10. Ascoli, M. (1982) J. Biol. Chem. 257, 13306-13311
11. Ghinea, N., Vuhai, M. T., Groyer-Picard, M.-T., Houllier, A., Schoëvaërt, D., and Milgrom, E. (1992) J. Cell Biol. 118, 1347-1358
12. Hoelscher, S. R., Sairam, M. R., and Ascoli, M. (1991) Endocrinology 128, 2837-2843
13. Dhanwada, K. R., Vijapurkar, U., and Ascoli, M. (1996) Mol. Endocrinol. 10, 544-554
14. Ascoli, M. (1984) J. Cell Biol. 99, 1242-1250
15. Wang, H., Segaloff, D. L., and Ascoli, M. (1991) J. Biol. Chem. 266, 780-785
16. McFarland, K. C., Sprengel, R., Phillips, H. S., Kohler, M., Rosemblit, N., Nikolics, K., Segaloff, D. L., and Seeburg, P. H. (1989) Science 245, 494-499
17. Damke, H., Baba, T., Warnock, D. E., and Schmid, S. L. (1994) J. Cell Biol. 127, 915-934
18. Chen, C., and Okayama, H. (1987) Mol. Cell Biol. 7, 2745-2752
19. Fabritz, J., Ryan, S., and Ascoli, M. (1998) Biochemistry 37, 664-672
20. Rosemblit, N., Ascoli, M., and Segaloff, D. L. (1988) Endocrinology 123, 2284-2290
21. Rodríguez, M. C., and Segaloff, D. L. (1990) Endocrinology 127, 674-681
22. Sterne-Marr, R., Gurevich, V. V., Goldsmith, P., Bodine, R. C., Sanders, C., Donoso, L. A., and Benovic, J. L. (1993) J. Biol. Chem. 268, 15640-15648
23. Donoso, L. A., Gregerson, D. S., Smith, L., Robertson, S., Knospe, V., Vrabec, T., and Kalsow, C. M. (1990) Curr. Eye Res. 9, 343-355
24. Ascoli, M., and Puett, D. (1978) Proc. Natl. Acad. Sci. U. S. A. 75, 99-102
25. Strickland, T. W., and Puett, D. (1981) Endocrinology 109, 1933-1942
26. Ascoli, M., and Segaloff, D. L. (1987) Endocrinology 120, 1161-1172
27. Mukherjee, S., Ghosh, R. N., and Maxfield, F. R. (1997) Physiol. Rev. 77, 759-803
28. Warnock, D., and Schmid, S. (1996) BioEssays 18, 885-893
29. Zhang, J., Ferguson, S. S. G., Barak, L. S., Menard, L., and Caron, M. G. (1996) J. Biol. Chem. 271, 18302-18305
30. Vieira, A. V., Lamaze, C., and Schmid, S. L. (1996) Science 274, 2086-2089
31. Pals-Rylaarsdam, R., Gurevich, V. V., Lee, K. B., Ptasienski, J. A., Benovic, J. L., and Hosey, M. M. (1997) J. Biol. Chem. 272, 23682-23689
32. Heuser, J. E., and Anderson, R. G. W. (1989) J. Cell Biol. 108, 389-400
33. Ferguson, S. S. G., Downey, W. E., Colapietro, A., Barak, L. B., Menard, L., and Caron, M. C. (1996) Science 271, 363-365
34. Zhang, J., Barak, L. S., Winkler, K. E., Caron, M. G., and Ferguson, S. S. G. (1997) J. Biol. Chem. 272, 27005-27014
35. Menard, L., Fergusson, S. S. G., Zhang, J., Lin, F.-T., Lefkowitz, R. J., Caron, M. G., and Barak, L. S. (1997) Mol. Pharmacol. 51, 800-808
36. Schlador, M. L., and Nathanson, N. M. (1997) J. Biol. Chem. 272, 18882-18890
37. Pippig, S., Andexinger, S., Daniel, K., Puzicha, M., Caron, M. G., Lefkowitz, R. J., and Lohse, M. J. (1993) J. Biol. Chem. 268, 3201-3208
38. Wilden, U., Hall, S. W., and Kühn, H. (1986) Proc. Natl. Acad. Sci. U. S. A. 83, 1174-1178
39. Krupnick, J. G., Gurevich, V. V., and Benovic, J. L. (1997) J. Biol. Chem. 272, 18125-18131
40. Xu, J., Dodd, R. L., Makino, C. L., Simon, M. I., Baylor, D. A., and Chen, J. (1997) Nature 389, 505-509
41. Pitcher, J. A., Lohse, M. J., Codina, J., Caron, M. G., and Lefkowitz, R. J. (1992) Biochemistry 31, 3193-3197
42. Pals-Rylaarsdam, R., and Hosey, M. M. (1997) J. Biol. Chem. 272, 14152-14158