Interleukin-12 and allergic tissue response

Clinical and Experimental Allergy

Volumn 29, Issue 10, 1999, Pages 1298-1300

  Camporota, L ^a   Holloway, J W ^a  

^a UNIVERSITY OF SOUTHAMPTON   (United Kingdom)

Author keywords

[No Author keywords available]

Indexed keywords

CYTOKINE; INTERLEUKIN 12; INTERLEUKIN 13; INTERLEUKIN 4; INTERLEUKIN 5;

AIRWAY; ALLERGIC ASTHMA; ALLERGIC RHINITIS; ALLERGY; ATOPY; EDITORIAL; HUMAN; IMMUNE RESPONSE; INFLAMMATION; PRIORITY JOURNAL; T LYMPHOCYTE ACTIVATION; T LYMPHOCYTE SUBPOPULATION;

EID: 0032835842     PISSN: 09547894     EISSN: None     Source Type: Journal    
DOI: 10.1046/j.1365-2222.1999.00694.x     Document Type: Editorial

References (33)

1. 1 Djukanovic R, Roche WR, Wilson JW Mucosal inflammation in asthma. Am Rev Respir Dis 1990 ; 142: 434 57.
2. 2 Abbas AK, Murphy KM, Sher A. Functional diversity of helper T lymphocytes. Nature 1996 ; 383: 787 93.
3. 3 Romagnani S. The Th1/Th2 paradigm. Immunol Today 1997 ; 18: 263 6.
4. 4 Mosmann TR & Sad S. The expanding universe of T‐cell subsets. Th1, Th2 and more. Immunol Today 1996 ; 17: 138 46.
5. 5 Seder RA, Paul WE, Davis MM, Fazekas de St Groth B. The presence of interleukin 4 during in vitro priming determines the lymphokine‐producing potential of CD4 + T cells from T cell receptor transgenic mice. J Exp Med 1992 ; 176: 1091 8.
6. 6 Seder RA, Gazzinelli R, Sher A, Paul WE. Interleukin 12 acts directly on CD4 + T cells to enhance priming for interferon gamma production and diminishes interleukin 4 inhibition of such priming. Proc Natl Acad Sci USA 1993 ; 90: 10188 92.
7. 7 Magram J, Connaughton SE, Warrier RR IL‐12‐deficient mice are defective in IFN‐γ production and type 1 cytokine responses. Immunity 1996 ; 4: 471 81.
8. 8 Wang ZE, Zheng S, Corry DB Interferon gamma‐independent effects of interleukin 12 administered during acute or established infection due to Leishmania major. Proc Natl Acad Sci USA 1994 ; 91: 12932 6.
9. 9 Finkelman FD, Madden KB, Cheever AW Effects of interleukin 12 on immune responses and host protection in mice infected with intestinal nematode parasites. J Exp Med 1994 ; 179: 1563 72.
10. 10 Morris SC, Madden KB, Adamovicz JJ Effects of IL‐12 on in vivo cytokine gene expression and Ig isotype selection. J Immunol 1994 ; 152: 1047 56.
11. 11 D'Andrea A, Ma X, Aste‐Amezaga M, Paganin C, Trinchieri G. Stimulatory and inhibitory effects of interleukin (IL) ‐4 and IL‐13 on the production of cytokines by human peripheral blood mononuclear cells: priming for IL‐12 and tumor necrosis factor alpha production. J Exp Med 1995 ; 181: 537 46.
12. 12 Szabo SJ, Dighe AS, Gubler U, Murphy KM. Regulation of the interleukin (IL)‐12R β 2 subunit expression in developing T helper 1 (Th1) and Th2 cells. J Exp Med 1997 ; 185: 817 24.
13. 13 Kobayashi M, Fitz L, Ryan M Identification and purification of natural killer cell stimulatory factor (NKSF), a cytokine with multiple biologic effects on human lymphocytes. J Exp Med 1989 ; 170: 827 45.
14. 14 Trinchieri G. Interleukin‐12: a cytokine produced by antigen‐presenting cells with immunoregulatory functions in the generation of T‐helper cells type 1 and cytotoxic lymphocytes. Blood 1994 ; 84: 4008 27.
15. 15 Gubler U, Chua AO, Schoenhaut DS Coexpression of two distinct genes is required to generate secreted bioactive cytotoxic lymphocyte maturation factor. Proc Natl Acad Sci USA 1991 ; 88: 4143 7.
16. 16 Hsieh CS, Macatonia SE, Tripp CS, Wolf SF, O'Garra A, Murphy KM. Development of TH1 CD4 + T cells through IL–12 produced by Listeria–induced macrophages. Science 1993 ; 260: 547 9.
17. 17 Trinchieri G. Interleukin‐12 and its role in the generation of TH1 cells. Immunol Today 1993 ; 14: 335 8.
18. 18 Manetti R, Parronchi P, Giudizi MG Natural killer cell stimulatory factor (interleukin 12 [IL‐12]) induces T helper type 1 (Th1) ‐specific immune responses and inhibits the development of IL‐4‐producing Th cells. J Exp Med 1993 ; 177: 1199 204.
19. 19 Desai BB, Quinn PM, Wolitzky AG, Mongini PK, Chizzonite R, Gately MK. IL‐12 receptor. II. Distribution and regulation of receptor expression. J Immunol 1992 ; 148: 3125 32.
20. 20 Rogge L, Barberis‐Maino L, Biffi M, Passini N, Presky DH, Gubler U, Sinigaglia F. Selective expression of an interleukin‐12 receptor component by human T helper 1 cells. J Exp Med 1997 ; 185: 825 31.
21. 21 Hilkens CM, Messer G, Tesselaar K, Van Rietschoten AG, Kapsenberg ML, Wierenga EA. Lack of IL‐12 signaling in human allergen‐specific Th2 cells. J Immunol 1996 ; 157: 4316 21.
22. 22 Shirakawa T, Enomoto T, Shimazu S, Hopkin JM. The inverse association between tuberculin responses and atopic disorder. Science 1997 ; 275: 77 9.
23. 23 Wright ED, Christodoulopoulos P, Frenkiel S, Hamid Q. Expression of interleukin‐(IL)12 (p40) and IL‐12 (β2) receptors in allergic rhinitis and chronic sinusitis. Clin Exp Allergy 1999 ; 29: 1320 5.
24. 24 Naseer T, Minshall EM, Leung DY Expression of IL‐12 and IL‐13 mRNA in asthma and their modulation in response to steroid therapy. Am J Respir Crit Care Med 1997 ; 155: 845 51.
25. 25 Van Der Pouw Kraan TC, Boeije LC, De Groot ER Reduced production of IL‐12 and IL‐12‐dependent IFN‐γ release in patients with allergic asthma. J Immunol 1997 ; 158: 5560 5.
26. 26 Van Der Pouw Kraan TC, Boeije LC, Smeenk RJ, Wijdenes J, Aarden LA. Prostaglandin‐E 2 is a potent inhibitor of human interleukin 12 production. J Exp Med 1995 ; 181: 775 9.
27. 27 Van Der Pouw Kraan TC, Snijders A, Boeije LC Histamine inhibits the production of interleukin–12 through interaction with H 2 receptors. J Clin Invest 1998 ; 102: 1866 73.
28. 28 DeKruyff RH, Fang Y, Umetsu DT. Corticosteroids enhance the capacity of macrophages to induce Th2 cytokine synthesis in CD4 + lymphocytes by inhibiting IL‐12 production. J Immunol 1998 ; 160: 2231 7.
29. 29 Blotta MH, DeKruyff RH, Umetsu DT. Corticosteroids inhibit IL‐12 production in human monocytes and enhance their capacity to induce IL‐4 synthesis in CD4 + lymphocytes. J Immunol 1997 ; 158: 5589 95.
30. 30 Gavett SH, O'Hearn DJ, Li X, Huang SK, Finkelman FD, Wills‐Karp M. Interleukin 12 inhibits antigen‐induced airway hyperresponsiveness, inflammation, and Th2 cytokine expression in mice. J Exp Med 1995 ; 182: 1527 36.
31. 31 Kips JC, Brusselle GJ, Joos GF Interleukin‐12 inhibits antigen‐induced airway hyperresponsiveness in mice. Am J Respir Crit Care Med 1996 ; 153: 535 9.
32. 32 Hogan SP, Foster PS, Tan X, Ramsay AJ. Mucosal IL‐12 gene delivery inhibits allergic airways disease and restores local antiviral immunity. Eur J Immunol 1998 ; 28: 413 23.
33. 33 Hamid QA, Schotman E, Jacobson MR, Walker SM, Durham SR. Increases in IL‐12 messenger RNA + cells accompany inhibition of allergen‐induced late skin responses after successful grass pollen immunotherapy. J Allergy Clin Immunol 1997 ; 99: 254 60.