Pharmacologic and molecular discrimination of I1-imidazoline receptor subtypes

Annals of the New York Academy of Sciences

Volumn 881, Issue , 1999, Pages 144-160

  Olmos, Gabriel ^a   Alemany, Regina ^a   Boronat, M Assumpció ^a   García Sevilla, Jesús A ^a  

^a UNIVERSITAT DE LES ILLES BALEARS   (Spain)

Author keywords

[No Author keywords available]

Indexed keywords

AMILORIDE; AMILORIDE DERIVATIVE; CLORGYLINE; GUANIDINE DERIVATIVE; IDAZOXAN; IMIDAZOLINE; IMIDAZOLINE I2 RECEPTOR; ISOTHIOCYANIC ACID DERIVATIVE; MEDETOMIDINE; MOXONIDINE; RECEPTOR PROTEIN; RECEPTOR SUBTYPE;

ANIMAL TISSUE; BINDING SITE; BRAIN CORTEX; BRAIN MEMBRANE; CONFERENCE PAPER; DRUG POTENCY; LIGAND BINDING; MALE; NONHUMAN; RABBIT; RAT; RECEPTOR AFFINITY; WESTERN BLOTTING;

ANIMALIA; ORYCTOLAGUS CUNICULUS;

EID: 0032796367     PISSN: 00778923     EISSN: None     Source Type: Book Series    
DOI: 10.1111/j.1749-6632.1999.tb09354.x     Document Type: Conference Paper

References (52)

1. Bousquet, P. 1995. Imidazoline receptors: From basic concepts to recent developments. J. Cardiovasc. Pharmacol. 26: S1-S6.
2. 2 sites in the mammalian central nervous system. Pharmacol. Ther. 68: 175-208.
3. Molderings, G. J. 1997. Imidazoline receptors: Basic knowledge, recent advances and future prospects for therapy and diagnosis. Drugs Fut. 22: 757-772.
4. 1-imidazoline sites in bovine adrenal medullary membranes. Naunyn-Schmiedeberg's Arch. Pharmacol. 348: 70-76.
5. 3H]RX821002 (2-methoxy idazoxan) in the human and rat brains. J. Pharmacol. Exp. Ther. 264: 1187-1197.
6. Limon, I., I. Coupry, S. M. Lanier & A. Parini. 1992. Purification and characterization of mitochondrial imidazoline-guanidinium receptive site from rabbit kidney. J. Biol. Chem. 267: 21645-21649.
7. Diamant, S., T. Eldar-Geva & D. Atlas. 1992. Imidazoline binding sites in human placenta: Evidence for heterogeneity and a search for physiologic function. Br. J. Pharmacol. 106: 101-108.
8. Olmos, G., R. Alemany, P. V. Escriba & J. A. García-Sevillia. 1994. The effects of chronic imidazoline drug treatment on glial fibrillary acidic protein concentrations in rat brain. Br. J. Pharmacol. 111: 997-1002.
9. 2 receptors, on glial fibrillary acidic protein concentration. Eur. J. Pharmacol. 280: 205-210.
10. 2-adrenergic receptor antagonist, decreases neuronal damage in the rat brain. J. Cereb. Blood Flow Metab. 9: 171-174.
11. Maiese, K., L. Pek, S. B. Berger & D. J. Reis. 1992. Reduction in focal cerebral ischemia by agents acting at imidazole receptors. J. Cereb. Blood Flow Metab. 12: 53-63.
12. 2-imidazoline ligands. Br. J. Pharmacol. 125: 175-185.
13. 3H]rauwolscine binding sites in rabbit urethra. Eur. J. Pharmacol. 164: 167-170.
14. 2-adrenoceptors in rabbit adipocyte membranes. Eur. J. Pharmacol. 159: 199-203.
15. Tesson, F., I. Limon & A. Parini. 1992. Tissue-specific localization of mitochondrial imidazoline-guanidinium receptive sites. Eur. J. Pharmacol. 219: 335-338.
16. Michel, M. C. & P. A. Insel. 1989. Are there multiple imidazoline binding sites? Trends Pharmacol. Sci. 10: 342-344.
17. 2-adrenoceptor? Eur. J. Pharmacol. 190: 203-215.
18. Wikberg, J. E. S. & S. Uhlén. 1990. Further characterization of the guinea pig cerebral cortex idazoxan receptor: Solubilization, distinction from the imidazole site, and demonstration of cirazoline as an idazoxan receptor selective drug. J. Neurochem. 55: 192-203.
19. Regunathan, S., M. P. Meeley & D. J. Reis. 1993. Expression of non-adrenergic imidazoline sites in chromaffin cells and mitochondrial membranes of bovine adrenal medulla. Biochem. Pharmacol. 45: 1667-1675.
20. Wikberg, J. E. S., S. Uhlén & V. Chhajlani. 1991. Metodomidine stereoisomers delineate two closely related subtypes of idazoxan (imidazoline) I-receptors in the guinea pig. Eur. J. Pharmacol. 193: 335-340.
21. 3H]-idazoxan binding sites (I-receptors) occurs to interacting or interconvertible affinity forms of the receptor. Pharmacol. Toxicol. 70: 208-219.
22. 3H]-idazoxan binding sites in the rat brain. Br. J. Pharmacol. 108: 597-603.
23. 2 imidazoline-preferring receptors. Br. J. Pharmacol. 114: 837-845.
24. 2-imidazoline binding sites on monoamine oxidases. J. Biol. Chem. 270: 9856-9861.
25. Parini, A., C. G. Moudanos, N. Pizzinat & S. M. Lanter. 1996. The elusive family of imidazoline binding sites. Trends Pharmacol. Sci. 17: 13-16.
26. 3H]-idazoxan binding sites. Br. J. Pharmacol. 118: 2029-2036.
27. Olmos, G., A. Miralles, F. Barturen & J. A. García-Sevilla. 1992. Characterization of brain imidazoline receptors in normotensive and hypertensive rats: Differential regulation by chronic imidazoline drug treatment. J. Pharmacol. Exp. Ther. 260: 1000-1007.
28. 3H]2-(2-benzofuranyl)-2-imidazoline (2-BFI) in rat brain and liver: Characterization, regulation and relation to monoamine oxidase enzymes. Naunyn-Schmiedeberg's Arch. Pharmacol. 356: 39-47.
29. 2-type receptors: Pharmacological characterization and relationship to monoamine oxidase. Br. J. Pharmacol. 109: 625-631.
30. 2-imidazoline binding sites in rat and rabbit tissues. Naunyn-Schmiedeberg's Arch. Pharmacol. 357: 351-355.
31. Munson, P. J. & D. Rodbard. 1980. LIGAND: A versatile computerized approach for the characterization of ligand binding systems. Anal. Biochem. 107: 220-239.
32. McPherson, G. A. 1985. Analysis of radioligand binding experiments: A collection of computer programs for IBM PC. J. Pharmacol. Meth. 14: 213-228.
33. Escribá, P. V., M. Sastre, H. Wang, S. Regunathan, D. J. Reis & J. A. García-Sevilla. 1994. Immunodetection of putative imidazoline receptor proteins in the human and rat brain and other tissues. Neurosci. Lett. 178: 81-84.
34. Wang, H., S. Regunathan, D. A. Ruggiero & D. J. Reis. 1993. Production and characterization of antibodies specific for the imidazoline receptor protein. Mol. Pharmacol. 43: 509-515.
35. 2-imidazoline receptor subtypes. Naunyn-Schmiedeberg's Arch. Pharmacol. 354: 709-716.
36. Li, G., S. Regunathan, C. J. Barrow, J. Eshraghi, R. Cooper & D. J. Reis. 1994. Agmatine, an endogenous clonidine-displacing substance in the brain. Science 263: 966-969.
37. Hollingworth, R. M., J. Leister & G. Ghali. 1979. Mode of action of formamidine pesticides: An evaluation of monoamine oxidase as the target. Chem. Biol. Interactions 24: 35-49.
38. Ishikawa, H., D. D. Miller & P. N. Patil. 1996. Irreversible agonist and antagonist properties of isothiocyanatobenzyl imidazoline in albino rabbit iris muscles. Naunyn-Schmiedeberg's Arch. Pharmacol. 354: 362-368.
39. 3H]idazoxan in the smooth muscle of rabbit urethra. Eur. J. Pharmacol. 154: 209-212.
40. 2-adrenergic drugs also bind with high affinity to a nonadrenergic site. Mol. Pharmacol. 35: 324-330.
41. 1-imidazoline sites. J. Pharmacol. Exp. Ther. 264: 172-182.
42. Piletz, J. E. & K. Sletten. 1993. Nonadrenergic imidazoline binding sites on human platelets. J. Pharmacol. Exp. Ther. 267: 1493-1502.
43. Tesson, F., C. Prip-Buus, A. Lemoine, J.-P. Pegorier & A. Parini. 1991. Subcellular distribution of imidazoline-guanidinium-receptive sites in human and rabbit liver. J. Biol. Chem. 266: 155-160.
44. 2-receptors. Ann. N.Y. Acad. Sci. 763: 43-56.
45. Ivanov, T. R., H. Zhu, S. Regunathan, D. J. Reis, M. Dontenwill, C. Vonthron, P. Bousquet & J. E. Piletz. 1998. Co-detection by two imidazoline receptor protein antisera of a novel 85 kilodalton protein. Biochem. Pharmacol. 55: 649-655.
46. Lanier, B., R. Raddatz, V. Bakthavachalam, I. Coupry, J. L. Neumeyer & S. M. Lanier. 1995. Structural and ligand recognition properties of imidazoline binding proteins in tissues of rat and rabbit. Mol. Pharmacol. 48: 703-710.
47. 2+ mobilization from thapsigargin-sensitive stores in mouse pancreatic b-cells. Diabetes 47: 211-218.
48. Raddatz, R., A. Parini & S. M. Lanier. 1995. Imidazoline/guanidinium binding domains on monoamine oxidases. J. Biol. Chem. 270: 27961-27968.
49. Bach, A. W., N. C. Lan, D. L. Jonhson, C. W. Abell, M. E. Bembenek, S. W. Kwan, P. H. Seeburg & J. C. Shih. 1988. cDNA cloning of human liver monoamine oxidase A and B. Molecular basis of differences in enzymatic properties. Proc. Natl. Acad. Sci. USA 85: 4934-4938.
50. 3H]-Ro 19-6327 in vitro: Localization and abundance of MAO-A and MAO-B in rat CNS, peripheral organs and human brain. J. Neurosci. 12: 1977-1999.
51. 2 sites. J. Pharmacol. Exp. Ther. 272: 681-688.
52. 2-imidazoline receptors in rat liver. Br. J. Pharmacol. 121: 901-912.