Solid-phase synthesis in lead optimization and drug discovery

Current Opinion in Drug Discovery and Development

Volumn 2, Issue 4, 1999, Pages 350-357

  Ellingboe, John W ^a  

^a PFIZER INC   (United States)

Author keywords

Parallel synthesis; Solid phase; Split pool

Indexed keywords

AMPRENAVIR; MATRIX METALLOPROTEINASE; PHOSPHODIESTERASE INHIBITOR; PROTEINASE INHIBITOR; SERINE PROTEINASE; THROMBIN INHIBITOR;

ARTICLE; DRUG SCREENING; DRUG SYNTHESIS; ENZYME INHIBITION; SOLID PHASE EXTRACTION;

EID: 0032789220     PISSN: 13676733     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

References (19)

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19. This paper is a good example of solid-phase synthesis employing the split/pool approach.