Modulation of proliferation and chemosensitivity by procathepsin D and its peptides in ovarian cancer

Gynecologic Oncology

Volumn 74, Issue 2, 1999, Pages 181-187

  Bazzett, Lisa B ^a   Watkins, Christopher S ^a   Gercel Taylor, Cicek ^a   Taylor, Douglas D ^a  

^a University of Louisville School of Medicine   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

CATHEPSIN D; CISPLATIN; PROCATHEPSIN D; UNCLASSIFIED DRUG;

ARTICLE; CELL PROLIFERATION; CHEMOSENSITIVITY; CLINICAL ARTICLE; CONTROLLED STUDY; FEMALE; HUMAN; HUMAN CELL; LD 50; OVARY CANCER; PRIORITY JOURNAL; REVERSED PHASE HIGH PERFORMANCE LIQUID CHROMATOGRAPHY; TUMOR CELL; TUMOR GROWTH;

EID: 0032766254     PISSN: 00908258     EISSN: None     Source Type: Journal    
DOI: 10.1006/gyno.1999.5426     Document Type: Article

References (33)

1. Richo G, Conner GE: Proteolytic activation of human procathepsin D, Adv Exp Med Biol 306:289-296, 1991
2. Conner GE, Richo G: Isolation and characterization of a stable activation intermediate of the lysosomal aspartyl protease cathepsin D, Biochemistry 31:1142-1147, 1992
3. Zhu Y, Conner GE: Intermolecular association of lysosomal protein precursors during biosynthesis, J Biol Chem 269:3846-3851, 1994
4. Laury-Kleintop LD, Coronel EC, Lange MK, Tachovsky T, Long S, Tucker S, Alhadeff JA: Western blotting and isoform analysis of cathepsin D from normal and malignant human breast cell lines, Breast Cancer Res Treat 35:211-220, 1995
5. Kawada A, Hara K, Kominami E, Kobayashi T, Hiruma M, Ishibashi A: Cathepsin B and D expression in squamous cell carcinoma, Br J Dermatol 135:905-910, 1996
6. Losch A, Kohlberger P, Gitsch G, Kaider A, Breitenecker G, Kainz C: Lysosomal protease cathepsin D is a prognostic marker in endometrial cancer, Br J Cancer 73:1525-1528, 1996
7. Tumminello FM, Leto G, Pizzolanti G, Candiloro V, Crescimanno M, Crosta L, Flandina C, Montalto G, Soresi M, Carroccio A, Bascone F, Ruggeri I, Ippolito S, Gebbia N: Cathepsin D, B, and L circulating levels as prognostic markers of malignant progression, Anticancer Res 16:2315-2319, 1996
8. Hennebicq-Reig S, Kim I, Janin A, Grard G, Hemon B, Moreau O, Porchet N, Aubert JP, Degand P, Huet G: Regulation of cathepsin D dependent on the colon carcinoma cells, Int J Cancer 68:479-484, 1996
9. Scambia G, Panici PB, Ferrandina G, Salerno G, D'Agostino G, Distefano M, deVincenzo R, Ercoli A, Mancuso S: Clinical significance of cathepsin D in primary ovarian cancer, Eur J Cancer 30A:935-940, 1994
10. Conner GE: The role of the cathepsin D pro-peptide in sorting to the lysosome, J Biol Chem 267:21738-21745, 1992
11. Garcia M, Derocq D, Pujol P, Rochefort H: Overexpression of transfected cathepsin D in transformed cells increases their malignant phenotype and metastatic potency, Oncogene 5:1809-1814, 1990
12. Scarborough PE, Guruprasad K, Topham C, Richo GR, Conner GE, Blundell TL, Dunn BM: Exploration of subsite binding specificity of human cathepsin D through kinetics and rule-based molecular modeling, Protein Sci 2:264-276, 1993
13. Rochefort H, Liaudet E, Garcia M: Alterations and role of human cathepsin D in cancer metastasis, Enzyme Protein 49:106-116, 1996
14. Garcia M, Salazar-Retana G, Richer G, Domergue J, Capony F, Pujol H, Laffargue F, Pau B, Rochefort H: Immunohistochemical detection of the estrogen-regulated Mr 52,000 protein in primary breast cancers but not in normal breast and uterus, J Clin Endocrinol Metab 59:564-566, 1984
15. Capony F, Rougeot C, Montcourrier P, Cavailles V, Salazar G, Rochefort H: Increased secretion, altered processing, and glycosylation of pro-Cathepsin D in human mammary cancer cells, Cancer Res 49:3904-3909, 1989
16. Maudelonde T, Khalaf S, Garcia M, Freiss G, Duporté J, Benatia M, Rogier H, Paolucci F, Simony J, Pujol H, Pau B, Rochefort H: Immunoenzymatic assay of Mr 52,000 cathepsin D in 182 breast cancer cytosols. Low correlation with other prognostic parameters, Cancer Res 48:462-465, 1988
17. Fusek M, Vetvicka V: Mitogenic function of human procathepsin D - role of the activation peptide, Biochem J 303:775-780, 1994
18. Cavailles V, Augereau P, Rochefort H: Cathepsin D gene is controlled by a mixed promoter, and estrogens stimulate only TATA-dependent transcription in breast cancer cells, Proc Natl Acad Sci USA 90:203-207, 1993
19. Liaudet E, Derocq D, Rochefort H, Garcia M: Transfected cathepsin D stimulates high density cancer cell growth by inactivating secreted growth inhibitors, Cell Growth Diff 6:1045-1052, 1995
20. Stewart AJ, Westley BR, May FEB: Modulation of the proliferative response of breast cancer cells to growth factors by estrogen, Br J Cancer 66:332-341, 1994
21. Korner C, Nurnberg B, Uhde M, Braulke T: Mannose-6-phosphate/insulin-like growth factor II receptor fails to interact with G-proteins, J Biol Chem 270:287-295, 1995
22. Vignon F, Capony F, Chambon M, Freiss G, Garcia M, Rochefort H: Autocrine growth stimulation of the MCF7 breast cancer cells by the estrogen-regulated 52K protein, Endocrinology 118:1537-1545, 1986
23. Vetvicka V, Vetvickova J, Fusek M: Participation of the propeptide on procathepsin D activation of human peripheral lymphocytes and neutrophils, Arch Biochem Biophys 322:295-298, 1995
24. Vetvicka V, Vetvickova J, Hilgert I, Voburka Z, Fusek M: Analysis of the interaction of procathepsin D activation peptide with breast cancer cells, Int J Cancer 73:403-409, 1997
25. Owens K, Gercel-Taylor C, Taylor DD, Day TG, Doering DL: Isolation and characterization of an ovarian carcinoma cell line as a model for drug resistance, Proc Am Assoc Cancer Res 34:26, 1993
26. Chinni SR, Gercel-Taylor C, Connor GE, Taylor DD: Cathepsin D antigenic epitopes identified by the humoral responses of ovarian cancer patients, Cancer Immunol Immunother 46:48-54, 1998
27. Laemmli UK: Cleavage of structural proteins during the assembly of the head of bacteriophage T4, Nature (Lond.) 227:680-685, 1970
28. Brown R, Clugston C, Burns P, Edlin A, Vasey P, Vojtesek B, Kaye SB: Increased accumulation of p53 protein in cisplatin-resistant ovarian cell lines, Int J Cancer 55:678-684, 1993
29. Briozzo P, Morisset M, Capony F, Rougeot C, Rochefort H: In vitro degradation of extracellular matrix with pro-cathepsin D secreted by breast cancer cells, Cancer Res 48:3688-3692, 1988
30. Rubinstein LV, Shoemaker RH, Paull KD, Simon RM, Tosini S, Skehan P, Scudiero DA, Monks A, Boyd MR: Comparison of in vitro anticancer-drug-screening data generated with a tetrazolium assay versus a protein assay against a diverse panel of human tumor cell lines, J Natl Cancer Inst 82:1113-1118, 1990
31. Brouillet JP, Dufour F, Lemamy G, Schlup N, Grenier J, Mani JC, Rochefort H: Increased cathepsin D level in the serum of patients with metastatic breast carcinoma detected with a specific pro-cathepsin D immunoassay, Cancer 79:2132-2136, 1997
32. Deiss LP, Galinka H, Berissi H, Cohen O, Kimchi A: Cathepsin D protease mediates programmed cell death by interferon-γ, Fas/APO-1 and TNF-α, EMBO J 15:3861-3870, 1996
33. Galtier-Dereure F, Capony F, Maudelonde T, Rochefort H: Estradiol stimulates cell growth and secretion of procathepsin D and a 120-kilodalton protein in the human ovarian cancer cell line BG-1, J Clin Endocrinol Metab 75:1497-1502, 1992