메뉴 건너뛰기




Volumn 19, Issue 5 B, 1999, Pages 4073-4080

2-(Allylthio)pyrazine suppresses the growth and proliferation of human promyelocytic leukemia (HL-60) cells via induction of apoptosis

Author keywords

2 (Allylthio)pyrazine; Antiproliferation; Apoptosis; Human promyelocytic; Leukemia cells; Organosulfur compounds

Indexed keywords

2 (ALLYLTHIO)PYRAZINE; DNA FRAGMENT; PROTEIN BAX; PROTEIN BCL 2; PYRAZINE DERIVATIVE; UNCLASSIFIED DRUG;

EID: 0032764101     PISSN: 02507005     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article
Times cited : (4)

References (64)
  • 1
    • 0031201202 scopus 로고    scopus 로고
    • The stinking rose: Organosulfur compounds and cancer
    • Heber D: The stinking rose: organosulfur compounds and cancer. Am J Clin Nutr 66: 425-426, 1997.
    • (1997) Am J Clin Nutr , vol.66 , pp. 425-426
    • Heber, D.1
  • 2
    • 0029836408 scopus 로고    scopus 로고
    • Organosulfur compounds and cancer
    • Lea MA: Organosulfur compounds and cancer. Adv Exp Med Biol 401: 147-154, 1996.
    • (1996) Adv Exp Med Biol , vol.401 , pp. 147-154
    • Lea, M.A.1
  • 3
    • 0023739534 scopus 로고
    • Effects of organosulfur compounds from garlic and onions on benzo[a]pyrene-induced neoplasia and glutathione S-transferase activity in the mouse
    • Sparnines VL, Barany G and Wattenberg L: Effects of organosulfur compounds from garlic and onions on benzo[a]pyrene-induced neoplasia and glutathione S-transferase activity in the mouse. Carcinogenesis 9: 131-134, 1988.
    • (1988) Carcinogenesis , vol.9 , pp. 131-134
    • Sparnines, V.L.1    Barany, G.2    Wattenberg, L.3
  • 4
    • 0030869443 scopus 로고    scopus 로고
    • Mechanism of differential efficacy of garlic organosulfides in preventing benzo[a]pyrene-induced cancer in mice
    • Srivastava SK, Hu X, Xia H, Zaren HA, Chatterjee ML, Agarwal R and Singh SV: Mechanism of differential efficacy of garlic organosulfides in preventing benzo[a]pyrene-induced cancer in mice. Cancer Lett 118: 61-67, 1997.
    • (1997) Cancer Lett , vol.118 , pp. 61-67
    • Srivastava, S.K.1    Hu, X.2    Xia, H.3    Zaren, H.A.4    Chatterjee, M.L.5    Agarwal, R.6    Singh, S.V.7
  • 5
    • 0031958996 scopus 로고    scopus 로고
    • Broccoli sprouts in cancer prevention
    • Nestle M: Broccoli sprouts in cancer prevention. Nutr Rev 56: 127-130, 1998.
    • (1998) Nutr Rev , vol.56 , pp. 127-130
    • Nestle, M.1
  • 6
    • 0028862921 scopus 로고
    • Chemoprotective effects of capsaicin and diallyl sulfide against mutagenesis and tumorigenesis by vinyl carbamate and N-nitrosodimethylamine
    • Surh Y-J, Lee RC, Park KK, Mayne ST, Liem A and Miller JA: Chemoprotective effects of capsaicin and diallyl sulfide against mutagenesis and tumorigenesis by vinyl carbamate and N-nitrosodimethylamine. Carcinogenesis 16: 2467-2471, 1995.
    • (1995) Carcinogenesis , vol.16 , pp. 2467-2471
    • Surh, Y.-J.1    Lee, R.C.2    Park, K.K.3    Mayne, S.T.4    Liem, A.5    Miller, J.A.6
  • 8
    • 0029566974 scopus 로고
    • Chemoprevention of diethylnitrosamine-induced liver foci and hepatocellular adenomas in C3H mice
    • Pereira MA: Chemoprevention of diethylnitrosamine-induced liver foci and hepatocellular adenomas in C3H mice. Anticancer Res 15: 1953-1956, 1995.
    • (1995) Anticancer Res , vol.15 , pp. 1953-1956
    • Pereira, M.A.1
  • 10
    • 0026780968 scopus 로고
    • Initiation and post-initiation chemopreventive effects of diallyl sulfide on esophageal carcinogenesis
    • Wargovich MJ, Imada O and Stephens LC: Initiation and post-initiation chemopreventive effects of diallyl sulfide on esophageal carcinogenesis. Cancer Lett 64: 39-42, 1992.
    • (1992) Cancer Lett , vol.64 , pp. 39-42
    • Wargovich, M.J.1    Imada, O.2    Stephens, L.C.3
  • 11
    • 0028203252 scopus 로고
    • Anticarcinogenic activities of sulforaphane and structurally related synthetic norbornyl isothiocyanates
    • Zhang Y, Kensler TW, Cho C-G, Posner GH and Talalay P: Anticarcinogenic activities of sulforaphane and structurally related synthetic norbornyl isothiocyanates. Proc Natl Acad Sci USA 91: 3147-3150, 1994.
    • (1994) Proc Natl Acad Sci USA , vol.91 , pp. 3147-3150
    • Zhang, Y.1    Kensler, T.W.2    Cho, C.-G.3    Posner, G.H.4    Talalay, P.5
  • 12
    • 0028946622 scopus 로고
    • Differential effects of dietary diallyl sulfide and diallyl disulfide on rat intestinal and hepatic drug-metabolizing enzymes
    • Harber D, Siess M-H, Canivenc-Lavier, MC, Le Bon A-M and Suschetet: Differential effects of dietary diallyl sulfide and diallyl disulfide on rat intestinal and hepatic drug-metabolizing enzymes. J Toxicol Environ Hlth 44: 423-434, 1995.
    • (1995) J Toxicol Environ Hlth , vol.44 , pp. 423-434
    • Harber, D.1    Siess, M.-H.2    Canivenc-Lavier, M.C.3    Le Bon, A.-M.4    Suschelet5
  • 13
    • 0030589723 scopus 로고    scopus 로고
    • Glutathione S-transferase of female A/J mouse liver and forestomach and their differential induction by anti-carcinogenic organosulfides from garlic
    • Hu X, Benson PJ, Srivastava SK, Mack LM, Xia H, Gupta V, Zaren HA and Singh SV: Glutathione S-transferase of female A/J mouse liver and forestomach and their differential induction by anti-carcinogenic organosulfides from garlic. Arch Biochem Biophys 336: 199-214, 1996.
    • (1996) Arch Biochem Biophys , vol.336 , pp. 199-214
    • Hu, X.1    Benson, P.J.2    Srivastava, S.K.3    Mack, L.M.4    Xia, H.5    Gupta, V.6    Zaren, H.A.7    Singh, S.V.8
  • 15
    • 0026577605 scopus 로고
    • A major inducer of anticarcinogenic protective enzymes from broccoli: Isolation and elucidation of structure
    • Zhang Y, Talalay P, Cho C-G and Posner GH: A major inducer of anticarcinogenic protective enzymes from broccoli: isolation and elucidation of structure. Proc Natl Acad Sci USA 89: 2399-2403, 1992.
    • (1992) Proc Natl Acad Sci USA , vol.89 , pp. 2399-2403
    • Zhang, Y.1    Talalay, P.2    Cho, C.-G.3    Posner, G.H.4
  • 17
    • 0030852501 scopus 로고    scopus 로고
    • Inhibition of cytochrome P-450 and induction of glutathione S-transferases by sulforaphane in primary human and rat hepatocytes
    • Maheo, K, Morel F, Langouet S, Kramer H, Le Ferree E, Ketterer B and Guillouzo A: Inhibition of cytochrome P-450 and induction of glutathione S-transferases by sulforaphane in primary human and rat hepatocytes. Cancer Res 57: 3649-3652, 1997.
    • (1997) Cancer Res , vol.57 , pp. 3649-3652
    • Maheo, K.1    Morel, F.2    Langouet, S.3    Kramer, H.4    Le Ferree, E.5    Ketterer, B.6    Guillouzo, A.7
  • 19
    • 0029551526 scopus 로고
    • A structurally atypical phenobarbital-type inducer
    • Dragnev KH, Nims RW and Lubet RA: A structurally atypical phenobarbital-type inducer. Biochem Pharmacol 50: 2099-2104, 1995.
    • (1995) Biochem Pharmacol , vol.50 , pp. 2099-2104
    • Dragnev, K.H.1    Nims, R.W.2    Lubet, R.A.3
  • 20
    • 0029888670 scopus 로고    scopus 로고
    • Modulation of rat hepatic cytochrome P-450 activity by garlic organosulfur compounds
    • Reicks MM and Crankshaw DL: Modulation of rat hepatic cytochrome P-450 activity by garlic organosulfur compounds. Nutr Cancer 25: 241-248, 1996.
    • (1996) Nutr Cancer , vol.25 , pp. 241-248
    • Reicks, M.M.1    Crankshaw, D.L.2
  • 21
    • 0029879994 scopus 로고    scopus 로고
    • CYP2E1-mediated mechanism of anti-genotoxicity of the broccoli constituent sulforaphane
    • Barcelo S, Gardiner JM, Gescher A and Chipman JK: CYP2E1-mediated mechanism of anti-genotoxicity of the broccoli constituent sulforaphane. Carcinogenesis 17: 277-282, 1996.
    • (1996) Carcinogenesis , vol.17 , pp. 277-282
    • Barcelo, S.1    Gardiner, J.M.2    Gescher, A.3    Chipman, J.K.4
  • 22
    • 0027377850 scopus 로고
    • Cancer Chemoprotection by oltipraz: Experimental and clinical considerations
    • Helzlsouer KJ and Kensler TW: Cancer Chemoprotection by oltipraz: experimental and clinical considerations. Prev Med 22: 783-795, 1993.
    • (1993) Prev Med , vol.22 , pp. 783-795
    • Helzlsouer, K.J.1    Kensler, T.W.2
  • 23
    • 0028904461 scopus 로고
    • Chemoprevention of colon carcinogenesis by sulindac, a nonsteroidal anti-inflammatory agent
    • Rao CV, Rivenson A, Simi B, Zang E, Kelloff G, Steele V and Reddy BS: Chemoprevention of colon carcinogenesis by sulindac, a nonsteroidal anti-inflammatory agent. Cancer Res 55: 1464-1472, 1995.
    • (1995) Cancer Res , vol.55 , pp. 1464-1472
    • Rao, C.V.1    Rivenson, A.2    Simi, B.3    Zang, E.4    Kelloff, G.5    Steele, V.6    Reddy, B.S.7
  • 26
    • 0029101403 scopus 로고
    • Probing the molecular program of apoptosis by cancer chemopreventive agents
    • Fesus L, Szondy Z and Uray I: Probing the molecular program of apoptosis by cancer chemopreventive agents. J Cell Biochem Suppl. 22: 151-161, 1995.
    • (1995) J Cell Biochem Suppl. , vol.22 , pp. 151-161
    • Fesus, L.1    Szondy, Z.2    Uray, I.3
  • 28
    • 0026517057 scopus 로고
    • Antiproliferative effect of the garlic compound S-allyl cysteine on human neuroblastoma cells in vitro
    • Welch C, Wuarin L and Sidell N: Antiproliferative effect of the garlic compound S-allyl cysteine on human neuroblastoma cells in vitro. Cancer Lett 63: 211-219, 1992.
    • (1992) Cancer Lett , vol.63 , pp. 211-219
    • Welch, C.1    Wuarin, L.2    Sidell, N.3
  • 29
    • 0028849168 scopus 로고
    • Selective toxicity of compounds naturally present in food toward the transformed phenotype of human colorectal cell line HT29
    • Musk SR, Stephenson P, Smith TK, Stening P, Fyfe D and Johnson IT: Selective toxicity of compounds naturally present in food toward the transformed phenotype of human colorectal cell line HT29. Nutr Cancer 24: 289-298, 1995.
    • (1995) Nutr Cancer , vol.24 , pp. 289-298
    • Musk, S.R.1    Stephenson, P.2    Smith, T.K.3    Stening, P.4    Fyfe, D.5    Johnson, I.T.6
  • 30
    • 0031057489 scopus 로고    scopus 로고
    • S-Allylmercaptocysteine inhibits cell proliferation and reduces the viability of erythroleukemia, breast, and prostate cancer cell lines
    • Sigounas G, Hooker J, Anagnostou A and Steiner M: S-Allylmercaptocysteine inhibits cell proliferation and reduces the viability of erythroleukemia, breast, and prostate cancer cell lines. Nutr Cancer 27: 186-191, 1997.
    • (1997) Nutr Cancer , vol.27 , pp. 186-191
    • Sigounas, G.1    Hooker, J.2    Anagnostou, A.3    Steiner, M.4
  • 31
    • 0029970362 scopus 로고    scopus 로고
    • Diallyl disulfide induces apoptosis of human colon tumor cells
    • Sundaram SG and Milner JA: Diallyl disulfide induces apoptosis of human colon tumor cells. Carcinogenesis 17: 669-673, 1996.
    • (1996) Carcinogenesis , vol.17 , pp. 669-673
    • Sundaram, S.G.1    Milner, J.A.2
  • 32
    • 0030826223 scopus 로고    scopus 로고
    • S-Allylmercaptocysteine, a stable thioallyl compound, induces apoptosis in erythroleukemia cell lines
    • Sigounas G, Hooker JL, Li W, Anagnostou A and Steiner M: S-Allylmercaptocysteine, a stable thioallyl compound, induces apoptosis in erythroleukemia cell lines. Nutr Cancer, 28: 153-159, 1997.
    • (1997) Nutr Cancer , vol.28 , pp. 153-159
    • Sigounas, G.1    Hooker, J.L.2    Li, W.3    Anagnostou, A.4    Steiner, M.5
  • 33
    • 0031445546 scopus 로고    scopus 로고
    • Allyl sulfide from garlic suppresses the in vitro proliferation of human A549 lung tumor cells
    • Sakamoto K, Lawson LD and Milner JA: Allyl sulfide from garlic suppresses the in vitro proliferation of human A549 lung tumor cells. Nutr Cancer 29: 152-156, 1997.
    • (1997) Nutr Cancer , vol.29 , pp. 152-156
    • Sakamoto, K.1    Lawson, L.D.2    Milner, J.A.3
  • 35
    • 0030968757 scopus 로고    scopus 로고
    • Apoptosis primarily accounts for the growth inhibitory properties of sulindac metabolites and involves a mechanism that is independent of cyclooxygenase inhibition, cell cycle arrest, and p53 induction
    • Piazza GA, Rham AK, Finn TS, Fryer BH, Li H, Stoumen AL, Pamukcu R and Ahnen D: Apoptosis primarily accounts for the growth inhibitory properties of sulindac metabolites and involves a mechanism that is independent of cyclooxygenase inhibition, cell cycle arrest, and p53 induction. Cancer Res 57: 2452-2459, 1997.
    • (1997) Cancer Res , vol.57 , pp. 2452-2459
    • Piazza, G.A.1    Rham, A.K.2    Finn, T.S.3    Fryer, B.H.4    Li, H.5    Stoumen, A.L.6    Pamukcu, R.7    Ahnen, D.8
  • 36
    • 0031047586 scopus 로고    scopus 로고
    • Inhibition of cytochrome P450 2E1 expression by 2-(allylthio)pyrazine, a potential chemoprotective agent: Hepatoprotective effects
    • Kim ND, Kwak MK and Kim SG: Inhibition of cytochrome P450 2E1 expression by 2-(allylthio)pyrazine, a potential chemoprotective agent: hepatoprotective effects. Biochem Pharmacol 53: 261-269, 1997.
    • (1997) Biochem Pharmacol , vol.53 , pp. 261-269
    • Kim, N.D.1    Kwak, M.K.2    Kim, S.G.3
  • 38
    • 0031926582 scopus 로고    scopus 로고
    • Chemoprentive effects of 2-(allylthio)pyrazine on hepatic lesion, mutagenesis and tumorigenesis induced by vinyl carbamate or vinyl carbamate epoxide
    • Surh Y-J, Kim SG, Park K-K, Sohn Y, Lee J-M, Kim N-D and Miller JA: Chemoprentive effects of 2-(allylthio)pyrazine on hepatic lesion, mutagenesis and tumorigenesis induced by vinyl carbamate or vinyl carbamate epoxide. Carcinogenesis 19: 1263-1267, 1998.
    • (1998) Carcinogenesis , vol.19 , pp. 1263-1267
    • Surh, Y.-J.1    Kim, S.G.2    Park, K.-K.3    Sohn, Y.4    Lee, J.-M.5    Kim, N.-D.6    Miller, J.A.7
  • 39
    • 0026599985 scopus 로고
    • Cell death by apoptosis and its protective role against disease
    • Bursch W, Oberhammer and Schulte-Hermann R: Cell death by apoptosis and its protective role against disease. Trends in Pharmacol Sci 13: 245-251, 1992.
    • (1992) Trends in Pharmacol Sci , vol.13 , pp. 245-251
    • Bursch, W.1    Oberhammer2    Schulte-Hermann, R.3
  • 40
    • 0344612163 scopus 로고
    • Apoptosis modulation gains drug company interest as critical therapeutic strategy
    • Danheiser SL: Apoptosis modulation gains drug company interest as critical therapeutic strategy. Genet Eng News, 15 (1): 22-23, 1995.
    • (1995) Genet Eng News , vol.15 , Issue.1 , pp. 22-23
    • Danheiser, S.L.1
  • 41
    • 0031031293 scopus 로고    scopus 로고
    • Apoptosis: Its role in the development of malignancies and its potential as a novel therapeutic target
    • Dixon SC, Soriano BJ, Lush RM, Borner MM and Figg WD: Apoptosis: its role in the development of malignancies and its potential as a novel therapeutic target. Ann Pharmacother 31: 76-82, 1997.
    • (1997) Ann Pharmacother , vol.31 , pp. 76-82
    • Dixon, S.C.1    Soriano, B.J.2    Lush, R.M.3    Borner, M.M.4    Figg, W.D.5
  • 42
    • 0028329172 scopus 로고
    • Apoptosis: Its significance in cancer and cancer therapy
    • Phila
    • Kerr JFR, Winterford CM and Harmon BV: Apoptosis: its significance in cancer and cancer therapy. Cancer (Phila) 73: 2013-2026, 1994.
    • (1994) Cancer , vol.73 , pp. 2013-2026
    • Kerr, J.F.R.1    Winterford, C.M.2    Harmon, B.V.3
  • 43
    • 0026698173 scopus 로고
    • Apoptosis induced by anticancer drugs
    • Hickman JA: Apoptosis induced by anticancer drugs. Cancer Metastasis Rev 11: 121-139, 1992.
    • (1992) Cancer Metastasis Rev , vol.11 , pp. 121-139
    • Hickman, J.A.1
  • 44
    • 0030772022 scopus 로고    scopus 로고
    • Target to apoptosis: A hopeful weapon for prostate cancer
    • Tang DG and Porter AT: Target to apoptosis: a hopeful weapon for prostate cancer. Prostate 32: 284-293, 1997.
    • (1997) Prostate , vol.32 , pp. 284-293
    • Tang, D.G.1    Porter, A.T.2
  • 45
    • 0028982219 scopus 로고
    • b-lapachone-mediated apoptosis in human promyelocytic leukemia (HL-60) and human prostate cancer cells: A p53-independent response
    • Planchon SM, Wuerzberger S, Frydman B, Witiak DT, Hutson P, Church DR, Wilding G and Boothman DA: b-lapachone-mediated apoptosis in human promyelocytic leukemia (HL-60) and human prostate cancer cells: a p53-independent response. Cancer Res 55: 3706-3711, 1995.
    • (1995) Cancer Res , vol.55 , pp. 3706-3711
    • Planchon, S.M.1    Wuerzberger, S.2    Frydman, B.3    Witiak, D.T.4    Hutson, P.5    Church, D.R.6    Wilding, G.7    Boothman, D.A.8
  • 46
    • 0029360394 scopus 로고
    • Induction of apoptosis by b-lapachone in human prostate cancer cells
    • Li CJ, Wang C and Pardee AB: Induction of apoptosis by b-lapachone in human prostate cancer cells. Cancer Res 55: 3712-3715, 1995.
    • (1995) Cancer Res , vol.55 , pp. 3712-3715
    • Li, C.J.1    Wang, C.2    Pardee, A.B.3
  • 47
    • 0031566154 scopus 로고    scopus 로고
    • Possible involvement of Bcl-2 pathway in retinoid X receptor alpha-induced apoptosis of HL-60 cells
    • Agarwal N and Mehta K: Possible involvement of Bcl-2 pathway in retinoid X receptor alpha-induced apoptosis of HL-60 cells. Biochem Biophys Res Commun 230: 251-253, 1997.
    • (1997) Biochem Biophys Res Commun , vol.230 , pp. 251-253
    • Agarwal, N.1    Mehta, K.2
  • 48
    • 0028040019 scopus 로고
    • Bcl-2 and the regulation of programmed cell death
    • Reed JC: Bcl-2 and the regulation of programmed cell death. J Cell Biol 124: 1-6, 1994.
    • (1994) J Cell Biol , vol.124 , pp. 1-6
    • Reed, J.C.1
  • 49
    • 0343811694 scopus 로고    scopus 로고
    • Modulation of NF-kB, p53 and Bcl-2 in apoptosis induced by cisplatin in HeLa cells
    • Maldonado V, Melendez-Zajgla J and Ortega A: Modulation of NF-kB, p53 and Bcl-2 in apoptosis induced by cisplatin in HeLa cells. Mutat Res 381: 67-75, 1997.
    • (1997) Mutat Res , vol.381 , pp. 67-75
    • Maldonado, V.1    Melendez-Zajgla, J.2    Ortega, A.3
  • 55
    • 0028222955 scopus 로고
    • Bcl-2 blocks p53-dependent apoptosis
    • Chiou S, Rao L and White E: Bcl-2 blocks p53-dependent apoptosis. Mol Cell Biol 14: 2556-2563, 1994.
    • (1994) Mol Cell Biol , vol.14 , pp. 2556-2563
    • Chiou, S.1    Rao, L.2    White, E.3
  • 56
    • 0001606206 scopus 로고
    • Major deletions in the gene encoding the p53 tumor antigen cause lack of p53 expression in HL-60 cells
    • Wolf D and Rotter V: Major deletions in the gene encoding the p53 tumor antigen cause lack of p53 expression in HL-60 cells. Proc Natl Acad Sci USA 82: 790-794, 1985.
    • (1985) Proc Natl Acad Sci USA , vol.82 , pp. 790-794
    • Wolf, D.1    Rotter, V.2
  • 57
    • 0028206341 scopus 로고
    • BH1 and BH2 domains of bcl-2 are required for inhibition of apoptosis and heterodimerization with bax
    • Yin X-M, Oltvai ZN and Lorsmeyer SJ: BH1 and BH2 domains of bcl-2 are required for inhibition of apoptosis and heterodimerization with bax. Nature 369: 321-323, 1994.
    • (1994) Nature , vol.369 , pp. 321-323
    • Yin, X.-M.1    Oltvai, Z.N.2    Lorsmeyer, S.J.3
  • 59
    • 0032568208 scopus 로고    scopus 로고
    • Overexpression of Bax gene sensitizes K562 erythroleukemia cells to apoptosis induced by selective chemotherapeutic agents
    • Kobayashi T, Ruan S, Clodi K, Kliche K-O, Shiku H, Andreeff M and Zhang W: Overexpression of Bax gene sensitizes K562 erythroleukemia cells to apoptosis induced by selective chemotherapeutic agents. Oncogene 16: 1587-1591, 1998.
    • (1998) Oncogene , vol.16 , pp. 1587-1591
    • Kobayashi, T.1    Ruan, S.2    Clodi, K.3    Kliche, K.-O.4    Shiku, H.5    Andreeff, M.6    Zhang, W.7
  • 60
    • 0027166048 scopus 로고
    • Bcl-2 heterodimerizes in vivo with a conserved homolog, Bax, that accelerates programmed cell death
    • Oltvai ZN, Milliman CL and Korsmeyer SJ: Bcl-2 heterodimerizes in vivo with a conserved homolog, Bax, that accelerates programmed cell death. Cell 74: 609-619, 1993.
    • (1993) Cell , vol.74 , pp. 609-619
    • Oltvai, Z.N.1    Milliman, C.L.2    Korsmeyer, S.J.3
  • 61
  • 63
    • 0028102478 scopus 로고
    • Cleavage of poly(ADP-ribose)polymerase by a proteinase with properties like ICE
    • Lazebnik YA, Kaufmann SH, Desnoyers S, Poirier GG and Earnshaw WC: Cleavage of poly(ADP-ribose)polymerase by a proteinase with properties like ICE. Nature 371: 346-347, 1994.
    • (1994) Nature , vol.371 , pp. 346-347
    • Lazebnik, Y.A.1    Kaufmann, S.H.2    Desnoyers, S.3    Poirier, G.G.4    Earnshaw, W.C.5
  • 64
    • 0030581151 scopus 로고    scopus 로고
    • Induction of apoptotic program in cell-free extracts: Requirement for dATP and cytochrome c
    • Liu X, Kim CN, Yang J, Jemmerson R and Wang X: Induction of apoptotic program in cell-free extracts: requirement for dATP and cytochrome c. Cell 86: 147-157, 1996.
    • (1996) Cell , vol.86 , pp. 147-157
    • Liu, X.1    Kim, C.N.2    Yang, J.3    Jemmerson, R.4    Wang, X.5


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.