Inhibition of cytochrome P450 2E1 expression by 2-(allylthio)pyrazine, a potential chemoprotective agent: Hepatoprotective effects

Biochemical Pharmacology

Volumn 53, Issue 3, 1997, Pages 261-269

  Kim, Nak Doo ^a   Kwak, Mi Kyong ^a   Kim, Sang Geon ^b  

^a Seoul National University   (South Korea)

^b Duksung Women's University   (South Korea)

Author keywords

2 (allylthio)pyrazine; cytochrome P450 2E1; enzyme inhibition; hepatoprotective agent

Indexed keywords

2 (ALLYLTHIO)PYRAZINE; 4 NITROPHENOL HYDROXYLASE; ALANINE AMINOTRANSFERASE; ASPARTATE AMINOTRANSFERASE; CARBON TETRACHLORIDE; CYTOCHROME P450 ISOENZYME; GLUTATHIONE; ISONIAZID; LIVER PROTECTIVE AGENT; MESSENGER RNA; OXYGENASE; PARACETAMOL; UNCLASSIFIED DRUG; UNSPECIFIC MONOOXYGENASE;

ALANINE AMINOTRANSFERASE BLOOD LEVEL; ANIMAL EXPERIMENT; ANIMAL TISSUE; ARTICLE; ASPARTATE AMINOTRANSFERASE BLOOD LEVEL; COMPETITIVE INHIBITION; CONTROLLED STUDY; DETOXIFICATION; ENZYME INHIBITION; FEMALE; GENETIC TRANSCRIPTION; IMMUNOBLOTTING; LIPID PEROXIDATION; LIVER MICROSOME; LIVER PROTECTION; MALE; METABOLIC ACTIVATION; MORTALITY; MOUSE; NONHUMAN; NORTHERN BLOTTING; ORAL DRUG ADMINISTRATION; PRIORITY JOURNAL; PROTEIN EXPRESSION; RAT;

ANIMALS; CARBON TETRACHLORIDE; CYTOCHROME P-450 CYP2E1; ENZYME INHIBITORS; FEMALE; GLUTATHIONE; LIVER; MALE; MICE; MICE, INBRED ICR; PYRAZINES; RATS; RATS, SPRAGUE-DAWLEY; RNA, MESSENGER;

EID: 0031047586     PISSN: 00062952     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0006-2952(96)00647-8     Document Type: Article

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