메뉴 건너뛰기




Volumn 13, Issue 17, 1999, Pages 2365-2376

Activation of CD8 T cells normalizes and correlates with the level of infectious provirus in tonsils during highly active antiretroviral therapy in early HIV-1 infection

Author keywords

Activation; Antiretroviral therapy; CD8; HIV 1; Lymphoid tissue; Viral load

Indexed keywords

ANTIRETROVIRUS AGENT; CD38 ANTIGEN; CD4 ANTIGEN; CD69 ANTIGEN; CD8 ANTIGEN; HLA DR ANTIGEN; INDINAVIR; LAMIVUDINE; ZIDOVUDINE;

EID: 0032762069     PISSN: 02699370     EISSN: None     Source Type: Journal    
DOI: 10.1097/00002030-199912030-00008     Document Type: Article
Times cited : (37)

References (53)
  • 1
    • 0023239322 scopus 로고
    • HIV-specific cytotoxic T lymphocytes in seropositive individuals
    • 1. Walker BD, Chakrabarti S, Moss B, et al. HIV-specific cytotoxic T lymphocytes in seropositive individuals. Nature 1987, 328:345-348.
    • (1987) Nature , vol.328 , pp. 345-348
    • Walker, B.D.1    Chakrabarti, S.2    Moss, B.3
  • 2
    • 0024323752 scopus 로고
    • T tell subset alterations in HIV-infected homosexual men: N1AID multicenter AIDS cohort study
    • 2. Giorgi JV, Detels R, T tell subset alterations in HIV-infected homosexual men: N1AID Multicenter AIDS cohort study. Clin Immunol Immunopathol 1989, 52:10-18.
    • (1989) Clin Immunol Immunopathol , vol.52 , pp. 10-18
    • Giorgi, J.V.1    Detels, R.2
  • 3
    • 0024403191 scopus 로고
    • T lymphocyte subset changes in human immunodeficiency virus infection
    • 3. Brinchmann JE, Vartdal F, Thorsby E. T lymphocyte subset changes in human immunodeficiency virus infection. J Acquir Immune Defic Syndr 1989, 2:398-403.
    • (1989) J Acquir Immune Defic Syndr , vol.2 , pp. 398-403
    • Brinchmann, J.E.1    Vartdal, F.2    Thorsby, E.3
  • 4
    • 0024556660 scopus 로고
    • Patterns of T lymphocyte changes with human immunodeficiency virus infection: From seroconversion to the development of AIDS
    • 4. Lang W, Perkins H, Anderson RE, Royce R, Jewell N, Winkelstein WJ. Patterns of T lymphocyte changes with human immunodeficiency virus infection: from seroconversion to the development of AIDS. J Acquir Immune Defic Syndr 1989, 2:63-69.
    • (1989) J Acquir Immune Defic Syndr , vol.2 , pp. 63-69
    • Lang, W.1    Perkins, H.2    Anderson, R.E.3    Royce, R.4    Jewell, N.5    Winkelstein, W.J.6
  • 5
    • 0024507703 scopus 로고
    • Follicular involution in HIV lymphadenopathy. A morphometric study
    • 5. Porwit A, Bottiger B, Pallesen G, Bodner A, Biberfeld P. Follicular involution in HIV lymphadenopathy. A morphometric study. APMIS 1989, 97:153-165.
    • (1989) APMIS , vol.97 , pp. 153-165
    • Porwit, A.1    Bottiger, B.2    Pallesen, G.3    Bodner, A.4    Biberfeld, P.5
  • 6
    • 0027328616 scopus 로고
    • Decline in the CD4 lymphocyte population in the blood of SIV-infected macaques is not reflected in lymph nodes
    • 6. Rosenberg YJ, Zack PM, White BD, et al. Decline in the CD4 lymphocyte population in the blood of SIV-infected macaques is not reflected in lymph nodes. AIDS Res Hum Retroviruses 1993, 9:639-646.
    • (1993) AIDS Res Hum Retroviruses , vol.9 , pp. 639-646
    • Rosenberg, Y.J.1    Zack, P.M.2    White, B.D.3
  • 8
    • 0029812505 scopus 로고    scopus 로고
    • Reduced CD4 cell counts in blood do not reflect CD4 cell depletion in tonsillar tissue in asymptomatic HIV-1 infection
    • 8. Røsok BI, Bostad L, Voltersvik P, et al. Reduced CD4 cell counts in blood do not reflect CD4 cell depletion in tonsillar tissue in asymptomatic HIV-1 infection. AIDS 1996, 10:F35-F38.
    • (1996) AIDS , vol.10
    • Røsok, B.I.1    Bostad, L.2    Voltersvik, P.3
  • 9
    • 0026735473 scopus 로고
    • The significance of activation markers on CD8 lymphocytes in human immunodeficiency syndrome: Staging and prognostic value
    • 9. Levacher M, Hulstaert F, Tallet S, Ullery S, Pocidalo JJ, Bach BA. The significance of activation markers on CD8 lymphocytes in human immunodeficiency syndrome: staging and prognostic value. Clin Exp Immunol 1992, 90:376-382.
    • (1992) Clin Exp Immunol , vol.90 , pp. 376-382
    • Levacher, M.1    Hulstaert, F.2    Tallet, S.3    Ullery, S.4    Pocidalo, J.J.5    Bach, B.A.6
  • 10
    • 0026694144 scopus 로고
    • Expression of activation antigens, HLA-DR and CD38, on CD8 lymphocytes during HIV-1 infection
    • 10. Kestens L, Vanham G, Gigase P, et al. Expression of activation antigens, HLA-DR and CD38, on CD8 lymphocytes during HIV-1 infection. AIDS 1992, 6:793-797.
    • (1992) AIDS , vol.6 , pp. 793-797
    • Kestens, L.1    Vanham, G.2    Gigase, P.3
  • 13
    • 0030045992 scopus 로고    scopus 로고
    • Correlation of CD8 lymphocyte activation with cellular viremia and plasma HIV RNA levels in asymptomatic patients infected by human immunodeficiency virus type 1
    • 13. Bouscarat F, Levacher-Clergeot M, Dazza MC, et al. Correlation of CD8 lymphocyte activation with cellular viremia and plasma HIV RNA levels in asymptomatic patients infected by human immunodeficiency virus type 1. AIDS Res Hum Retroviruses 1996, 12:17-24.
    • (1996) AIDS Res Hum Retroviruses , vol.12 , pp. 17-24
    • Bouscarat, F.1    Levacher-Clergeot, M.2    Dazza, M.C.3
  • 15
    • 8944259909 scopus 로고    scopus 로고
    • Increased numbers of primed activated CD8+CD38+CD45RO+ T cells predict the decline of CD4+ T cells in HIV-1-infected patients
    • 15. Bofill M, Mocroft A, Lipman M, et al. Increased numbers of primed activated CD8+CD38+CD45RO+ T cells predict the decline of CD4+ T cells in HIV-1-infected patients. AIDS 1996, 10:827-834.
    • (1996) AIDS , vol.10 , pp. 827-834
    • Bofill, M.1    Mocroft, A.2    Lipman, M.3
  • 20
    • 0032941595 scopus 로고    scopus 로고
    • + T cells are detectable in most individuals with active HIV-1 infection, hut decline with prolonged viral suppression
    • + T cells are detectable in most individuals with active HIV-1 infection, hut decline with prolonged viral suppression. Nat Med 1999, 5:518-525.
    • (1999) Nat Med , vol.5 , pp. 518-525
    • Pitcher, C.1    Quittner, C.2    Peterson, D.M.3
  • 21
    • 0030868897 scopus 로고    scopus 로고
    • + T cell homeostasis and function in advanced HIV disease
    • + T cell homeostasis and function in advanced HIV disease. Science 1997, 277:112-116.
    • (1997) Science , vol.277 , pp. 112-116
    • Autran, B.1    Carcelain, G.2    Ii, T.S.3
  • 22
    • 0032188878 scopus 로고    scopus 로고
    • Immunologic effects of combined protease inhibitor and reverse transcriptase inhibitor therapy in previously treated chronic: HIV-1 infection
    • 22. Giorgi JV, Majchrowicz MA, Johnson TD, Hultin P, Matud J, Detels R. Immunologic effects of combined protease inhibitor and reverse transcriptase inhibitor therapy in previously treated chronic: HIV-1 infection. AIDS 1998, 12:1833-1844.
    • (1998) AIDS , vol.12 , pp. 1833-1844
    • Giorgi, J.V.1    Majchrowicz, M.A.2    Johnson, T.D.3    Hultin, P.4    Matud, J.5    Detels, R.6
  • 23
    • 0032511914 scopus 로고    scopus 로고
    • Highly active antirelroviral therapy during early HIV infection reverses T cell activation and maturation abnormalities
    • 23. Bisset IR, Cone RW, Huber W, et al. Highly active antirelroviral therapy during early HIV infection reverses T cell activation and maturation abnormalities, AIDS 1998, 12:2115-2123.
    • (1998) AIDS , vol.12 , pp. 2115-2123
    • Bisset, I.R.1    Cone, R.W.2    Huber, W.3
  • 24
    • 0032080402 scopus 로고    scopus 로고
    • + T cell subsets in response to highly active antiretroviral therapy in HIV type 1-infected patients with prior protease inhibitor experience
    • + T cell subsets in response to highly active antiretroviral therapy in HIV type 1-infected patients with prior protease inhibitor experience. AIDS Res Hum Retroviruses 1998, 14:561-569.
    • (1998) AIDS Res Hum Retroviruses , vol.14 , pp. 561-569
    • Gray, C.M.1    Schapiro, J.M.2    Winters, M.A.3    Merigan, T.C.4
  • 26
    • 0032549551 scopus 로고    scopus 로고
    • Phenotypic variability of lymphocyte populations in peripheral blood and lymph nodes from HIV-infected individuals and the impact of antiretroviral therapy. DATRI 003 Study Group. Division of AIDS Treatment Research Initiative
    • 26. Landay AL, Bethel J, Schnittman S. Phenotypic variability of lymphocyte populations in peripheral blood and lymph nodes from HIV-infected individuals and the impact of antiretroviral therapy. DATRI 003 Study Group. Division of AIDS Treatment Research Initiative. AIDS Res Hum Retroviruses 1998, 14:445-451.
    • (1998) AIDS Res Hum Retroviruses , vol.14 , pp. 445-451
    • Landay, A.L.1    Bethel, J.2    Schnittman, S.3
  • 27
    • 0027122957 scopus 로고
    • 1993 Revised classification system for HIV infection and expanded surveillance case definition for AIDS among adolescents and adults
    • 27. Centers for Disease Control and Prevention. 1993 revised classification system for HIV infection and expanded surveillance case definition for AIDS among adolescents and adults. MMWR 1992, 41:1-19.
    • (1992) MMWR , vol.41 , pp. 1-19
  • 28
    • 0026011260 scopus 로고
    • + T cells but a high proportion of replication-competent provirus copies in asymptomatic human immunodeficiency virus type 1 infection
    • + T cells but a high proportion of replication-competent provirus copies in asymptomatic human immunodeficiency virus type 1 infection. J Virol 1991, 65:2019-2023.
    • (1991) J Virol , vol.65 , pp. 2019-2023
    • Brinchmann, J.F.1    Albert, J.2    Vartdal, F.3
  • 29
    • 0024471827 scopus 로고
    • Human immunodeficiency virus type 1 p24 production and antigenic variation in tissue culture of isolates with various growth characteristics
    • 29. Sundqvist VA, Albert J, Ohlsson E, Hinkula J, Fenyo EM, Wahren B. Human immunodeficiency virus type 1 p24 production and antigenic variation in tissue culture of isolates with various growth characteristics. J Med Virol 1989, 29:170-175.
    • (1989) J Med Virol , vol.29 , pp. 170-175
    • Sundqvist, V.A.1    Albert, J.2    Ohlsson, E.3    Hinkula, J.4    Fenyo, E.M.5    Wahren, B.6
  • 31
    • 0018428330 scopus 로고
    • Ia determinants on stimulated human T lymphocytes. Occurrence on mitogen-and antigen-activated T cells
    • 31. Ko HS, Fu SM, Winchester RJ, Yu DT, Kunkel HG. Ia determinants on stimulated human T lymphocytes. Occurrence on mitogen-and antigen-activated T cells. J Exp Med 1979, 150:246-255.
    • (1979) J Exp Med , vol.150 , pp. 246-255
    • Ko, H.S.1    Fu, S.M.2    Winchester, R.J.3    Yu, D.T.4    Kunkel, H.G.5
  • 32
    • 0025255387 scopus 로고
    • Transmission of signals from the T lymphocyte antigen receptor to the genes responsible for cell proliferation and immune function: The missing link
    • 32. Ullman KS, Northrop JP, Verweij CI, Crabtree GR. Transmission of signals from the T lymphocyte antigen receptor to the genes responsible for cell proliferation and immune function: the missing link. Annu Rev Immunol 1990, 8:421-452.
    • (1990) Annu Rev Immunol , vol.8 , pp. 421-452
    • Ullman, K.S.1    Northrop, J.P.2    Verweij, C.I.3    Crabtree, G.R.4
  • 33
    • 0031020747 scopus 로고    scopus 로고
    • Flow cytometric analysis of activation markers on stimulated T cells and their correlation with cell proliferation
    • 33. Caruso A, Licenziati S, Corulli M, et al. Flow cytometric analysis of activation markers on stimulated T cells and their correlation with cell proliferation. Cytometry 1997, 27:71-76.
    • (1997) Cytometry , vol.27 , pp. 71-76
    • Caruso, A.1    Licenziati, S.2    Corulli, M.3
  • 35
    • 0032953920 scopus 로고    scopus 로고
    • + T cells provides a mechanism for lifelong persistence of HIV-1, even in patients on effective combination therapy
    • + T cells provides a mechanism for lifelong persistence of HIV-1, even in patients on effective combination therapy. Nat Med 1999, 5:512-517.
    • (1999) Nat Med , vol.5 , pp. 512-517
    • Finzi, D.1    Blanksin, J.2    Siliciano, J.D.3
  • 37
    • 0031873665 scopus 로고    scopus 로고
    • +T cell renewal in early HIV-1 infection: Effect of highly active antiretroviral therapy
    • +T cell renewal in early HIV-1 infection: effect of highly active antiretroviral therapy. Nat Med 1998, 4:794-801.
    • (1998) Nat Med , vol.4 , pp. 794-801
    • Fleury, S.1    De Boer, R.J.2    Rizzardi, G.P.3
  • 38
    • 0040226744 scopus 로고
    • Discrete stages of human intrathymic differentiation: Analysis of normal thymocytes and leukemic lymphoblasts of T cell lineage
    • 38. Reinherz EL, Kung PC, Goldstein G, Levey RH, Schlossman SF. Discrete stages of human intrathymic differentiation: analysis of normal thymocytes and leukemic lymphoblasts of T cell lineage. Proc Natl Acad Sci USA 1980, 77:1588-1592.
    • (1980) Proc Natl Acad Sci USA , vol.77 , pp. 1588-1592
    • Reinherz, E.L.1    Kung, P.C.2    Goldstein, G.3    Levey, R.H.4    Schlossman, S.F.5
  • 39
    • 0025036264 scopus 로고
    • Involvement of the multilineage CD3B molecule in a unique pathway of cell activation and proliferation
    • 39. Funaro A, Spagnoli GC, Ausiello CM, et al. Involvement of the multilineage CD3B molecule in a unique pathway of cell activation and proliferation. J Immunol 1990, 145:2390-2396.
    • (1990) J Immunol , vol.145 , pp. 2390-2396
    • Funaro, A.1    Spagnoli, G.C.2    Ausiello, C.M.3
  • 40
    • 0029015478 scopus 로고
    • + cell turnover
    • discussion, 198
    • + cell turnover. Nature 1995, 375:193-194; discussion, 198.
    • (1995) Nature , vol.375 , pp. 193-194
    • Mosier, D.C.1
  • 41
    • 0029647392 scopus 로고
    • + cell turnover
    • discussion 198
    • + cell turnover. Nature 1995, 375:194; discussion 198
    • (1995) Nature , vol.375 , pp. 194
    • Sprent, J.1    Tough, D.2
  • 43
    • 0028811974 scopus 로고
    • Viral dynamics in human immunodeficiency virus type 1 infection
    • 43. Wei X, Ghosh SK, Taylor ME, et al. Viral dynamics in human immunodeficiency virus type 1 infection. Nature 1995, 373:117-122.
    • (1995) Nature , vol.373 , pp. 117-122
    • Wei, X.1    Ghosh, S.K.2    Taylor, M.E.3
  • 45
    • 0032814791 scopus 로고    scopus 로고
    • T cell changes after combined nucleoside analogue therapy in HIV primary infection
    • 45. Carcelain G, Blanc C, Leibowitch J, et al. T cell changes after combined nucleoside analogue therapy in HIV primary infection. AIDS 1999, 13:1077-1081.
    • (1999) AIDS , vol.13 , pp. 1077-1081
    • Carcelain, G.1    Blanc, C.2    Leibowitch, J.3
  • 47
    • 0029048581 scopus 로고
    • Fas antigen stimulation induces marked apoptosis of T lymphocytes in human immunodeficiency virus-infected individuals
    • 47. Katsikis PD, Wunderlich ES, Smith CA, Herzenberg LA. Fas antigen stimulation induces marked apoptosis of T lymphocytes in human immunodeficiency virus-infected individuals. J Exp Med 1995, 181:2029-2036.
    • (1995) J Exp Med , vol.181 , pp. 2029-2036
    • Katsikis, P.D.1    Wunderlich, E.S.2    Smith, C.A.3    Herzenberg, L.A.4
  • 48
    • 0029882175 scopus 로고    scopus 로고
    • Programmed cell death in peripheral lymphocytes from HIV-infected persons: Increased susceptibility to apoptosis of CD4 and CD8 T cells correlates with lymphocyte activation and with disease progression
    • 48. Gougeon ML, Lecoeur H, Dulioust A, et al. Programmed cell death in peripheral lymphocytes from HIV-infected persons: increased susceptibility to apoptosis of CD4 and CD8 T cells correlates with lymphocyte activation and with disease progression. J Immunol 1996, 156:3509-3520.
    • (1996) J Immunol , vol.156 , pp. 3509-3520
    • Gougeon, M.L.1    Lecoeur, H.2    Dulioust, A.3
  • 49
    • 0029840781 scopus 로고    scopus 로고
    • Rapid evolution of human immunodeficiency virus strains with increased replicative capacity during the seronegative window of primary infection
    • 49. Ferbas J, Daar ES, GroviT Ferbas K, et al. Rapid evolution of human immunodeficiency virus strains with increased replicative capacity during the seronegative window of primary infection. J Virol 1996, 70:7285-7289.
    • (1996) J Virol , vol.70 , pp. 7285-7289
    • Ferbas, J.1    Daar, E.S.2    Grovit Ferbas, K.3
  • 50
    • 0032581692 scopus 로고    scopus 로고
    • Changes in blood CD8+ lymphocyte activation status and plasma HIV RNA levels during antiretroviral therapy
    • 50. Bouscarat F, Levacher M, Landman R, et al. Changes in blood CD8+ lymphocyte activation status and plasma HIV RNA levels during antiretroviral therapy. AIDS 1998, 12:1267-1273.
    • (1998) AIDS , vol.12 , pp. 1267-1273
    • Bouscarat, F.1    Levacher, M.2    Landman, R.3
  • 51
    • 0031751647 scopus 로고    scopus 로고
    • + T cells correlate with plasma human immunodeficiency virus (HIV-1) RNA level in HIV-1 infection
    • + T cells correlate with plasma human immunodeficiency virus (HIV-1) RNA level in HIV-1 infection. J Infect Dis 1998, 178:1279-1287.
    • (1998) J Infect Dis , vol.178 , pp. 1279-1287
    • Orendi, J.M.1    Bloem, A.C.2    Borleffs, J.C.3
  • 52
    • 0031407423 scopus 로고    scopus 로고
    • Changes in CD8 cell subpopulations induced by antiretroviral therapy in human immunodeficiency virus infected patients
    • 52. Silvestri G, Munoz C, Butini L, Bagnarelli P, Montroni M. Changes in CD8 cell subpopulations induced by antiretroviral therapy in human immunodeficiency virus infected patients. Viral Immunol 1997, 10:207-212.
    • (1997) Viral Immunol , vol.10 , pp. 207-212
    • Silvestri, G.1    Munoz, C.2    Butini, L.3    Bagnarelli, P.4    Montroni, M.5
  • 53
    • 0027538456 scopus 로고
    • HIV infection is active and progressive in lymphoid tissue during the clinically latent stage of disease
    • 53. Pantaleo G, Graziosi C, Demarest JF, et al. HIV infection is active and progressive in lymphoid tissue during the clinically latent stage of disease. Nature 1993, 362:355-358.
    • (1993) Nature , vol.362 , pp. 355-358
    • Pantaleo, G.1    Graziosi, C.2    Demarest, J.F.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.