Activation and proliferation of CD8+ T cells in lymphoid tissues of HIV-1-infected individuals in the absence of the high-affinity IL-2 receptor

Journal of Acquired Immune Deficiency Syndromes and Human Retrovirology

Volumn 19, Issue 4, 1998, Pages 332-338

  Brinchmann, Jan E ^a   Røsok, Bård I ^b   Spurkland, Anne ^a  

^a OSLO UNIVERSITY HOSPITAL   (Norway)

^b UNIVERSITY OF BERGEN   (Norway)

Author keywords

CD25; CD8+ T cells; HIV 1; Lymphoid tissues; Proliferation

Indexed keywords

CD69 ANTIGEN; INTERLEUKIN 2; INTERLEUKIN 2 RECEPTOR; MESSENGER RNA;

ANTIGEN EXPRESSION; ARTICLE; CELL ACTIVATION; CELL PROLIFERATION; CELL SURFACE; CONTROLLED STUDY; HELPER CELL; HLA SYSTEM; HUMAN; HUMAN CELL; HUMAN IMMUNODEFICIENCY VIRUS 1; HUMAN IMMUNODEFICIENCY VIRUS INFECTION; LYMPHOID TISSUE; PRIORITY JOURNAL; RECEPTOR AFFINITY; T LYMPHOCYTE; T LYMPHOCYTE SUBPOPULATION;

EID: 0032400998     PISSN: 10779450     EISSN: None     Source Type: Journal    
DOI: 10.1097/00042560-199812010-00003     Document Type: Article

References (36)

1. Fauci AS. Multifactorial nature of human immunodeficiency virus disease: implications for therapy. Science 1993;262:1011-8.
2. Fahey JL, Taylor JM, Detels R, et al. The prognostic value of cellular and serologic markers in infection with human immunodeficiency virus type 1. N Engl J Med 1990;322:166-72.
3. Bentwich Z, Kalinkovich A, Weisman Z. Immune activation is a dominant factor in the pathogenesis of African AIDS. Immunol Today 1995;16:187-91.
4. Mohri H, Bonhoeffer S, Monard S, Perelson AS, Ho DD. Rapid turnover of T lymphocytes in SIV-infected rhesus macaques. Science 1998;279:1223-7.
5. Rosok BI, Bostad L, Voltersvik P, et al. Reduced CD4 cell counts in blood do not reflect CD4 cell depletion in tonsillar tissue in asymptomatic HIV-1 infection. AIDS 1996;10:F35-8.
6. + T cell repopulation of lymphoid tissues after treatment of HIV-1 infection. Proc Natl Acad Sci USA 1998;95:1154-9.
7. Rosok B, Brinchmann JE, Voltersvik P, Olofsson J, Bostad L, Asjo B. Correlates of latent and productive HIV type-1 infection in tonsillar CD4(+) T cells. Proc Natl Acad Sci USA 1997;94:9332-6.
8. 1993 revised classification system for HIV infection and expanded surveillance case definition for AIDS among adolescents and adults. MMWR Morb Mortal Wkly Rep 1992;41:1-19.
9. + T cells. Evidence for a soluble inhibitor. J Immunol 1990;144:2961-6.
10. Cosman D, Cerretti DP, Larsen A, et al. Cloning, sequence and expression of human interleukin-2 receptor. Nature 1984;312:768-71.
11. Leonard WJ, Depper JM, Crabtree GR, et al. Molecular cloning and expression of cDNAs for the human interleukin-2 receptor. Nature 1984;311:626-31.
12. Nikaido T, Shimizu A, Ishida N, et al. Molecular cloning of cDNA encoding human interleukin-2 receptor. Nature 1984;311:631-5.
13. Singer-Sam J, Robinson MO, Bellve AR, Simon MI, Riggs AD. Measurement by quantitative PCR of changes in HPRT, PGK-1, PGK-2, APRT, MTase, and Zfy gene transcripts during mouse spermatogenesis. Nucleic Acids Res 1990;18:1255-9.
14. β usage. Scand J Immunol 1994;39:387-94.
15. Taniguchi T, Minami Y. The IL-2/IL-2 receptor system: a current overview. Cell 1993;73:5-8.
16. Theze J, Alzari PM, Bertoglio J. Interleukin 2 and its receptors: recent advances and new immunological functions. Immunol Today 1996;17:481-6.
17. Caruso A, Licenziati S, Corulli M, et al. Flow cytometric analysis of activation markers on stimulated T cells and their correlation with cell proliferation. Cytometry 1997;27:71-6.
18. Ullman KS, Northrop JP, Verweij CL, Crabtree GR. Transmission of signals from the T lymphocyte antigen receptor to the genes responsible for cell proliferation and immune function: the missing link. Annu Rev Immunol 1990;8:421-52.
19. Biselli R, Matricardi PM, D'Amelio R, Fattorossi A. Multiparametric flow cytometric analysis of the kinetics of surface molecule expression after polyclonal activation of human peripheral blood T lymphocytes. Scand J Immunol 1992;35:439-47.
20. Babbitt BP, Allen PM, Matsueda G, Haber E, Unanue ER. Binding of immunogenic peptides to Ia histocompatibility molecules. Nature 1985;317:359-61.
21. Germain RN. The ins and outs of antigen processing and presentation. Nature 1986;322:687-9.
22. Bevan MJ. Antigen presentation to cytotoxic T lymphocytes in vivo. J Exp Med 1995;182:639-41.
23. Kagi MK, Fierz W, Grob PJ, Russi EW. High proportion of gamma-delta T cell receptor positive T cells in bronchoalveolar lavage and peripheral blood of HIV-infected patients with Pneumocystis carinii pneumonias. Respiration 1993;60:170-7.
24. + lymphocyte appears in lymph nodes of rhesus monkeys early after infection with simian immunodeficiency virus. J Clin Invest 1991; 88:1113-20.
25. Rosenberg YJ, Lewis MG, Villinger F, Ansari AA. Cytokines and simian immunodeficiency virus infections. Res Immunol 1994;145: 706-12.
26. + T cell depletion and viral replication in SIV infection. Science 1998;280:427-31.
27. Saltini C, Spurzem JR, Kirby MR. Crystal RG. Sarcoidosis is not associated with a generalized defect in T cell suppressor function. J Immunol 1988;140:1854-60.
28. Hol BE, Hintzen RQ, Van Lier RA, Alberts C, Out TA, Jansen HM. Soluble and cellular markers of T cell activation in patients with pulmonary sarcoidosis. Am Rev Respir Dis 1993;148:643-9.
29. Albera C, Ghio P, Solidoro P, Mabritto I, Marchetti L, Pozzi E. Activated and memory alveolar T-lymphocytes in idiopathic eosinophilic pneumonia. Eur Respir J 1995;8:1281-5.
30. Takeuchi Y, Yoshie H, Hara K. Expression of interleukin-2 receptor and HLA-DR on lymphocyte subsets of gingival crevicular fluid in patients with periodontitis. J Periodontal Res 1991;26: 502-10.
31. + alpha/ beta cells in the lamina propria but proliferation (Ki-67) of alpha/ beta and gamma/delta cells in the epithelium. Eur J Immunol 1993; 23:505-10.
32. Fernandez-Gutierrez B, Hernandez-Garcia C, Banares AA, Jover JA. Characterization and regulation of CD69 expression on rheumatoid arthritis synovial fluid T cells. J Rheumatol 1995;22:413-20.
33. Wilkerson MJ, Davis WC, Cheevers WP. Peripheral blood and synovial fluid mononuclear cell phenotypes in lentivirus induced arthritis. J Rheumatol 1995;22:8-15.
34. Johnson N, Parkin JM. Dysregulation of the interleukin-2 receptor alpha- and beta-chain expression in CD4 and CD8 T cells in HIV infection. Cytometry 1997;30:289-95.
35. Kovacs JA, Vogel S, Albert JM, et al. Controlled trial of interleukin-2 infusions in patients infected with the human immunodeficiency virus. N Engl J Med 1996;335:1350-6.
36. Nelson BH, Lord JD, Greenberg PD. Cytoplasmic domains of the interleukin-2 receptor beta and gamma chains mediate the signal for T-cell proliferation. Nature 1994;369:333-6.