Structures of competitive inhibitor complexes of protocatechuate 3,4- Dioxygenase: Multiple exogenous ligand binding orientations within the active site

Biochemistry

Volumn 36, Issue 33, 1997, Pages 10039-10051

  Orville, Allen M ^a,b   Elango, Natesan ^a   Lipscomb, John D ^a   Ohlendorf, Douglas H ^a  

^a UNIVERSITY OF MINNESOTA MEDICAL SCHOOL   (United States)

^b UNIVERSITY OF OREGON   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

PROTOCATECHUIC ACID;

ARTICLE; COMPETITIVE INHIBITION; CRYSTAL STRUCTURE; ENZYME ACTIVE SITE; ENZYME INHIBITOR COMPLEX; ENZYME STRUCTURE; ENZYME SUBSTRATE COMPLEX; LIGAND BINDING; PRIORITY JOURNAL; PSEUDOMONAS PUTIDA; STRUCTURE ANALYSIS;

BINDING SITES; BINDING, COMPETITIVE; COMPUTER SIMULATION; CRYSTALLOGRAPHY, X-RAY; ENZYME INHIBITORS; KINETICS; LIGANDS; MOLECULAR SEQUENCE DATA; MOLECULAR STRUCTURE; PROTOCATECHUATE-3,4-DIOXYGENASE; PSEUDOMONAS PUTIDA;

PSEUDOMONAS; PSEUDOMONAS PUTIDA;

EID: 0030874393     PISSN: 00062960     EISSN: None     Source Type: Journal    
DOI: 10.1021/bi970468n     Document Type: Article

References (43)

1. Arnez, J. G. (1994) J. Appl. Crystallogr. 27, 649-653.
2. Bernstein, F. C., Koetzle, T. F., Williams, G. J. B., Meyer, E. F., Jr., Brice, M. D., Rodgers, J. R., Kennard, O., Shimanouchi, T., & Tasumi, M. (1977) J. Mol. Biol. 112, 535-542.
3. Bull, C., Ballou, D. P., & Otsuka, S. (1981) J. Biol. Chem. 256, 12681-12686.
4. Felton, R. H., Cheung, L. D., Phillips, R. S., & May, S. W. (1978) Biochem. Biophys. Res. Commun. 85, 844-850.
5. Felton, R. H., Gordon, S. L., Sowell, A. L., & May, S. W. (1984) Biochemistry 23, 3955-3959.
6. Ferrin, T. E., Huang, C. C., Jarvis, L. E., & Langridge, R. (1988) J. Mol. Graphics 6, 13-27.
7. Fisher, C. L., Cabelli, D. F., Tainer, J. A., Hallewell, R. A., & Getzoff, E. D. (1994) Proteins 19, 24-34.
8. Frazee, R. W., Livingston, D. M., LaPorte, D. C., & Lipscomb, J. D. (1993) J. Bacteriol. 175, 6194-6202.
9. Fujisawa, H., & Hayaishi, O. (1968) J. Biol. Chem. 243, 2673-2681.
10. Fujiwara, M., & Nozaki, M. (1973) Biochim. Biophys. Acta 327, 306-312.
11. Getzoff, E. D., Cabelli, D. E., Fisher, C. L., Parge, H. E., Viezzoli, M. S., Banci, L., & Hallewell, R. A. (1992) Nature 358, 347-351.
12. Gilson, M. K., Sharp, K. A., & Honig, B. H. (1988) J. Comput. Chem. 9, 327-335.
13. Glusker, J. P. (1991) Adv. Protein Chem. 42, 1-76.
14. Hendrickson, W. A. (1985) Methods Enzymol. 115, 252-270.
15. Hendrickson, W. A., & Konnert, J. H. (1980) in Biomolecular Structure, Function, Conformation and Evolution (Srinvasan, R., Ed.) Vol. 1, pp 43-47, Pergamon, Oxford.
16. Honig, B. H., & Nicholls, A. (1995) Science 268, 1144-1149.
17. Howard, A. J., Gilliland, G. L., Finzel, B. C, Poulos, T. L., Ohlendorf, D. H., & Salemme, F. (1987) J. Appl. Crystallogr. 20, 383-387.
18. Howard, J. B., & Rees, D. C. (1991) Adv. Protein Chem. 42, 199-280.
19. Jones, T. A. (1978) J. Appl. Crystallogr. 11, 268-272.
20. Kraulis, P. J. (1991) J. Appl. Crystallogr. 24, 946-950.
21. Laskowski, R. A., MacArthur, M. W., Moss, S. D., & Thornton, J. M. (1993) J. Appl. Crystallogr. 26, 283-291.
22. Lipscomb, J. D., & Orville, A. M. (1992) in Metal Ions in Biological Systems (Sigel, H., & Sigel, A., Eds.) Vol. 28, pp 243-298, Marcel Dekker, Inc., New York.
23. May, S. W., & Phillips, R. S. (1979) Biochemistry 18, 5933-5939.
24. May, S. W., Phillips, R. S., & Oldham, C. D. (1978) Biochemistry 17, 1853-1860.
25. Michaud-Soret, I., Andersson, K. K., Que, L., Jr., & Haavik, J. (1995) Biochemistry 34, 5504-5510. Ohlendorf, D. H., Weber, P. C., & Lipscomb, J. D. (1987) J. Mol. Biol. 195, 225-227.
26. Michaud-Soret, I., Andersson, K. K., Que, L., Jr., & Haavik, J. (1995) Biochemistry 34, 5504-5510. Ohlendorf, D. H., Weber, P. C., & Lipscomb, J. D. (1987) J. Mol. Biol. 195, 225-227.
27. Ohlendorf, D. H., Lipscomb, J. D., & Weber, P. C. (1988) Nature 336, 403-405.
28. Ohlendorf, D. H., Orville, A. M., & Lipscomb, J. D. (1994) J. Mol. Biol. 244, 586-608.
29. Orville, A. M., & Lipscomb, J. D. (1989) J. Biol. Chem. 264, 8791-8801.
30. Orville, A. M., & Lipscomb, J. D. (1993) J. Biol. Chem. 268, 8596-8607.
31. Orville, A. M., Lipscomb, J. D., & Ohlendorf, D. H. (1997) Biochemistry 36, 10052-10066.
32. Que, L., Jr. (1989) in Iron Carriers and Iron Proteins (Loehr, T. M., Ed.) pp 467-524, VCH, New York.
33. Que, L., Jr. (1993) in Bioinorganic Catalysis (Reedijk, J., Ed.) pp 347-393, Marcel Dekker, Inc., New York.
34. Que L., Jr., & Epstein, R. M. (1981) Biochemistry 20, 2545-2549.
35. Que, L., Jr., & Ho, R. Y. N. (1996) Chem. Rev. 96, 2607-2624.
36. Que, L., Jr., Lipscomb, J. D., Zimmermann, R., Münck, E., Orme-Johnson, N. R., & Orme-Johnson, W. H. (1976) Biochim. Biophys. Acta 452, 320-334.
37. Siu, D. C.-T., Orville, A. M., Lipscomb, J. D., Ohlendorf, D. H., & Que, L., Jr. (1992) Biochemistry 31, 10443-10448.
38. Smith, R. H., & Martell, A. E. (1989) in Critical Stability Constants, Vol. 6, Plenum Press, New York (supplemental no. 2 and earlier volumes).
39. True, A. E., Orville, A. M., Pearce, L. L., Lipscomb, J. D., & Que, L., Jr. (1990) Biochemistry 29, 10847-10854.
40. Whittaker, J. W., & Lipscomb, J. D. (1984a) J. Biol. Chem. 259, 4476-4486.
41. Whittaker, J. W., & Lipscomb, J. D. (1984b) J. Biol. Chem. 259, 4487-4495.
42. Whittaker, J. W., Lipscomb, J. D., Kent, T. A., & Münck, E. (1984) J. Biol. Chem. 259, 4466-4475.
43. Whittaker, J. W., Orville, A. M., & Lipscomb, J. D. (1990) Methods Enzymol. 188, 82-88.