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Volumn 21, Issue 4, 1999, Pages 645-665

Combined antiviral therapy reduces HIV-1 plasma load and improves CD4 counts but does not interfere with ongoing lymphocyte apoptosis

Author keywords

[No Author keywords available]

Indexed keywords

CERAMIDE; DIDANOSINE; ZIDOVUDINE;

EID: 0032758573     PISSN: 08923973     EISSN: None     Source Type: Journal    
DOI: 10.3109/08923979909007132     Document Type: Article
Times cited : (3)

References (65)
  • 2
    • 0028909872 scopus 로고
    • Quantitation of HIV-1 RNA in plasma predicts outcome after seroconversion
    • Mellors, J.W., Kingsley, L.A., Rinaldo, C.R. Jr. et al., Quantitation Of HIV-1 RNA In Plasma Predicts Outcome After Seroconversion. Ann. Intern. Med., 122: 573, 1995.
    • (1995) Ann. Intern. Med. , vol.122 , pp. 573
    • Mellors, J.W.1    Kingsley, L.A.2    Rinaldo C.R., Jr.3
  • 3
    • 0028024718 scopus 로고
    • The natural history of HIV-1 infection: Virus load and virus phenotype independent determinants of clinical course?
    • Jurriaans, S., Van Gemen, B., Weverling, G.J. et al., The Natural History Of HIV-1 Infection: Virus Load And Virus Phenotype Independent Determinants Of Clinical Course? Virology, 204: 223, 1994.
    • (1994) Virology , vol.204 , pp. 223
    • Jurriaans, S.1    Van Gemen, B.2    Weverling, G.J.3
  • 4
    • 0029081506 scopus 로고
    • Natural history of HIV-1 cell-free viremia
    • Henrard, D.R., Philips, J.F., Muenz, L.R. et al., Natural History Of HIV-1 Cell-free Viremia. JAMA, 274: 554, 1995.
    • (1995) JAMA , vol.274 , pp. 554
    • Henrard, D.R.1    Philips, J.F.2    Muenz, L.R.3
  • 6
    • 0027538456 scopus 로고
    • HIV infection is active and progressive in lymphoid tissue during the clinically latent stage of disease
    • Pantaleo, G., Graziosi, C., Demarest, J.F. et al., HIV Infection Is Active And Progressive In Lymphoid Tissue During The Clinically Latent Stage Of Disease. Nature, 362: 355, 1993.
    • (1993) Nature , vol.362 , pp. 355
    • Pantaleo, G.1    Graziosi, C.2    Demarest, J.F.3
  • 7
    • 0029977995 scopus 로고    scopus 로고
    • Outpatient biopsies of the palatin tonsil: Access to lymphoid for assessment of human immunodeficiency virus RNA titers
    • Faust, R.A., Henry, K., Dailey, P. et al., Outpatient Biopsies Of The Palatin Tonsil: Access To Lymphoid For Assessment Of Human Immunodeficiency Virus RNA Titers. Otolaryngol. Head Neck. Surg., 114: 593, 1996.
    • (1996) Otolaryngol. Head Neck. Surg. , vol.114 , pp. 593
    • Faust, R.A.1    Henry, K.2    Dailey, P.3
  • 8
    • 0030010777 scopus 로고    scopus 로고
    • Human immunodeficiency virus type 1 kinetics in lymph nodes compared with plasma
    • Lafeuillade, A., Poggi, C., Profizi, N., Tamalet, C. and Costes, O., Human Immunodeficiency Virus Type 1 Kinetics In Lymph Nodes Compared With Plasma. J. Infect. Dis., 174: 404, 1996.
    • (1996) J. Infect. Dis. , vol.174 , pp. 404
    • Lafeuillade, A.1    Poggi, C.2    Profizi, N.3    Tamalet, C.4    Costes, O.5
  • 9
    • 0029016740 scopus 로고
    • Decreased human immunodeficiency virus type 1 plasma viremia during antiretroviral therapy reflects down regulation of viral replication in lymphoid tissue
    • Cohen, O.J., Pantaleo, G., Holodniy, M. et al., Decreased Human Immunodeficiency Virus Type 1 Plasma Viremia During Antiretroviral Therapy Reflects Down Regulation Of Viral Replication In Lymphoid Tissue. Proc. Natl. Acad. Sci. USA, 92: 6017, 1995.
    • (1995) Proc. Natl. Acad. Sci. USA , vol.92 , pp. 6017
    • Cohen, O.J.1    Pantaleo, G.2    Holodniy, M.3
  • 10
    • 19144363743 scopus 로고    scopus 로고
    • Antiretroviral monotherapy in early stage human immunodeficiency virus disease has no detectable effect on virus load in peripheral blood and lymph nodes
    • Cohen, O.J., Pantaleo, G., Holodniy, M. et al., Antiretroviral Monotherapy In Early Stage Human Immunodeficiency Virus Disease Has No Detectable Effect On Virus Load In Peripheral Blood And Lymph Nodes. J. Infect. Dis., 173: 849, 1996.
    • (1996) J. Infect. Dis. , vol.173 , pp. 849
    • Cohen, O.J.1    Pantaleo, G.2    Holodniy, M.3
  • 11
    • 0344461995 scopus 로고    scopus 로고
    • HIV RNA levels in lymphoid tissue, peripheral blood leukocytes (PBMC) and plasma (PL) fractions of HIV-infected individuals
    • (Washington, D.C.). Aexandria, Virginia: Infectious Diseases Society of America
    • Erice, A., Daileym P., Haasem A., et al., HIV RNA Levels In Lymphoid Tissue, Peripheral Blood Leukocytes (PBMC) And Plasma (PL) Fractions Of HIV-Infected Individuals [abstract 260]. In: Program and abstracts of the Third Conferences on Retroviruses and Opportunistic Infections (Washington, D.C.). Aexandria, Virginia: Infectious Diseases Society of America, 1996.
    • (1996) Program and Abstracts of the Third Conferences on Retroviruses and Opportunistic Infections
    • Erice, A.1    Daileym, P.2    Haasem, A.3
  • 12
    • 0029773395 scopus 로고    scopus 로고
    • Viral load and immunophenotype of cells obtained from lymph nodes by fine needle aspiration as compared with peripheral blood cells in HIV-infected patients
    • Meylan, P.R.A., Burgisser, P., Weyrich-Suter, C. and Spertini, F., Viral Load And Immunophenotype Of Cells Obtained From Lymph Nodes By Fine Needle Aspiration As Compared With Peripheral Blood Cells In HIV-Infected Patients. J. Acquired Immune Defic. Syndr., 13: 39, 1996.
    • (1996) J. Acquired Immune Defic. Syndr. , vol.13 , pp. 39
    • Meylan, P.R.A.1    Burgisser, P.2    Weyrich-Suter, C.3    Spertini, F.4
  • 14
    • 0031052933 scopus 로고    scopus 로고
    • Human immunodeficiency virus (HIV) RNA in plasma as the preferred target for therapy in patients with HIV infection: A critique
    • Fessel, W.J., Human Immunodeficiency Virus (HIV) RNA In Plasma As The Preferred Target For Therapy In Patients With HIV Infection: A Critique. Clin. Infect. Dis., 24: 116, 1997.
    • (1997) Clin. Infect. Dis. , vol.24 , pp. 116
    • Fessel, W.J.1
  • 16
    • 0028811974 scopus 로고
    • Viral dynamic in human immunodeficiency virus type 1 infection
    • Wei, X., Ghosh, S.K., Taylor, M.E., et al., Viral Dynamic In Human Immunodeficiency Virus Type 1 Infection. Nature, 373: 117, 1995.
    • (1995) Nature , vol.373 , pp. 117
    • Wei, X.1    Ghosh, S.K.2    Taylor, M.E.3
  • 17
    • 0029967721 scopus 로고    scopus 로고
    • HIV-1 dynamic in vivo: Virion clearance rate, infected cell life-span, and viral generation time
    • Perelson, A.S., Neumann, A.U., Markowitz, M., Leonard, J.M. and Ho, D.D., HIV-1 Dynamic In Vivo: Virion Clearance Rate, Infected Cell Life-Span, And Viral Generation Time. Science, 271: 1582, 1996.
    • (1996) Science , vol.271 , pp. 1582
    • Perelson, A.S.1    Neumann, A.U.2    Markowitz, M.3    Leonard, J.M.4    Ho, D.D.5
  • 18
    • 0028912254 scopus 로고
    • Apoptosis occurs predominantly in bystander cells and not in productively infected cells of HIV-and SIV-infected lymph nodes
    • Finkel, T.H., Tudor-Williams, G., Banda, N.K, et al., Apoptosis Occurs Predominantly In Bystander Cells And Not In Productively Infected Cells Of HIV-And SIV-Infected Lymph Nodes. Nat. Med., 2: 129, 1995.
    • (1995) Nat. Med. , vol.2 , pp. 129
    • Finkel, T.H.1    Tudor-Williams, G.2    Banda, N.K.3
  • 19
    • 0029027684 scopus 로고
    • Presence of CD3+ CD8+ Bcl-2 low lymphocytes undergoing apoptosis and activated macrophages in lymph nodes of HIV-1+ patients
    • Bofill, M., Gombert, W., Borthwick, N.J. et al., Presence Of CD3+ CD8+ Bcl-2 Low Lymphocytes Undergoing Apoptosis And Activated Macrophages In Lymph Nodes Of HIV-1+ Patients. Am. J. Pathol., 146: 1542, 1995.
    • (1995) Am. J. Pathol. , vol.146 , pp. 1542
    • Bofill, M.1    Gombert, W.2    Borthwick, N.J.3
  • 20
    • 0029034517 scopus 로고
    • Analysis of apoptosis in lymph nodes of HIV-infected persons: Intensity of apoptosis correlates with the general state of activation of the lymphoid tissue and not with the stage of disease or viral burden
    • Muro-Cacho, C.A., Pantaleo, G. and Fauci, A.S., Analysis Of Apoptosis In Lymph Nodes Of HIV-Infected Persons: Intensity Of Apoptosis Correlates With The General State Of Activation Of The Lymphoid Tissue And Not With The Stage Of Disease Or Viral Burden. J. Immunol., 154: 5555, 1995.
    • (1995) J. Immunol. , vol.154 , pp. 5555
    • Muro-Cacho, C.A.1    Pantaleo, G.2    Fauci, A.S.3
  • 22
    • 0026517545 scopus 로고
    • Activation-induced death by apoptosis in CD4+ T cells from human immunodeficiency virus-infected asymptomatic individuals
    • Groux, H., Torpier, G., Monte, D., Mouton, Y., Capron, A. and Ameisen, J.C., Activation-Induced Death By Apoptosis In CD4+ T Cells From Human Immunodeficiency Virus-Infected Asymptomatic Individuals. J. Exp. Med. 175: 331, 1992.
    • (1992) J. Exp. Med. , vol.175 , pp. 331
    • Groux, H.1    Torpier, G.2    Monte, D.3    Mouton, Y.4    Capron, A.5    Ameisen, J.C.6
  • 26
    • 0029882175 scopus 로고    scopus 로고
    • Programmed cell death in peripheral lymphocytes from HIV-infected persons: The increased susceptibility to apoptosis of CD4 and CD8 T cells correlates with lymphocyte activation and with disease progression
    • Gougeon, M.L., Lecoeur, H., Dulioust, A. et al., Programmed Cell Death In Peripheral Lymphocytes From HIV-Infected Persons: The Increased Susceptibility To Apoptosis Of CD4 And CD8 T Cells Correlates With Lymphocyte Activation And With Disease Progression. J. Immunol., 156: 3509, 1996.
    • (1996) J. Immunol. , vol.156 , pp. 3509
    • Gougeon, M.L.1    Lecoeur, H.2    Dulioust, A.3
  • 27
    • 0029980469 scopus 로고    scopus 로고
    • Apoptosis associated with ex vivo downregulation of Bcl-2 and upregulation of fas in potential cytotoxic CD8+ T lymphocytes
    • Boudet, F., Lecoeur, H. and Gougeon, M.L., Apoptosis Associated With Ex Vivo Downregulation Of Bcl-2 And Upregulation Of Fas In Potential Cytotoxic CD8+ T Lymphocytes. J. Immunol., 156: 2282, 1996.
    • (1996) J. Immunol. , vol.156 , pp. 2282
    • Boudet, F.1    Lecoeur, H.2    Gougeon, M.L.3
  • 28
    • 0029941931 scopus 로고    scopus 로고
    • Cell-associated ceramide in HIV-1-infected subjects
    • De Simone, C., Cifone, M.G., Di Marzio, L. et al., Cell-Associated Ceramide In HIV-1-Infected Subjects. AIDS, 10: 675, 1996.
    • (1996) AIDS , vol.10 , pp. 675
    • De Simone, C.1    Cifone, M.G.2    Di Marzio, L.3
  • 30
    • 0029048581 scopus 로고
    • Fas antigen stimulation induced marked apoptosis of T lymphocytes in HIV virus-infected individuals
    • Katsikis, P.D., Wunderlich, E.S., Craig, C.A. and Herzenberg, L.A., Fas Antigen Stimulation Induced Marked Apoptosis Of T Lymphocytes In HIV Virus-Infected Individuals. J. Exp. Med., 181: 2029, 1995.
    • (1995) J. Exp. Med. , vol.181 , pp. 2029
    • Katsikis, P.D.1    Wunderlich, E.S.2    Craig, C.A.3    Herzenberg, L.A.4
  • 31
    • 0029610188 scopus 로고
    • Fas (CD95) expression on CD4+ T cells from HIV-infected patients increases with disease progression
    • Aries, S.P., Schaaf, B., Muller, C., Dennin, R.H. and Dalhoff, K., Fas (CD95) Expression On CD4+ T Cells From HIV-Infected Patients Increases With Disease Progression. J. Mol. Med., 73: 591, 1995.
    • (1995) J. Mol. Med. , vol.73 , pp. 591
    • Aries, S.P.1    Schaaf, B.2    Muller, C.3    Dennin, R.H.4    Dalhoff, K.5
  • 32
    • 0030044207 scopus 로고    scopus 로고
    • Overexpression of fas antigen on T cells in advanced HIV-1 infection: Differential ligation constantly induces apoptosis
    • Silvestris, F., Cafforio, P., Frassanito, F.A. et al., Overexpression Of Fas Antigen On T Cells In Advanced HIV-1 Infection: Differential Ligation Constantly Induces Apoptosis. AIDS, 10: 131, 1996.
    • (1996) AIDS , vol.10 , pp. 131
    • Silvestris, F.1    Cafforio, P.2    Frassanito, F.A.3
  • 33
    • 0031049287 scopus 로고    scopus 로고
    • Role of fas ligand and receptor in the mechanism of T-cell depletion in acquired immunodeficiency syndrome: Effect on CD4+ lymphocyte depletion and human immunodeficiency virus replication
    • Sloand, E.M., Young, N.S., Kumar, P., Weichold, F.F., Sato, T. and Maciejewski, J.P., Role Of Fas Ligand And Receptor In The Mechanism Of T-Cell Depletion In Acquired Immunodeficiency Syndrome: Effect On CD4+ Lymphocyte Depletion And Human Immunodeficiency Virus Replication. Blood, 89: 1357, 1997.
    • (1997) Blood , vol.89 , pp. 1357
    • Sloand, E.M.1    Young, N.S.2    Kumar, P.3    Weichold, F.F.4    Sato, T.5    Maciejewski, J.P.6
  • 34
    • 0028265466 scopus 로고
    • High expression of APO-1 (CD95) on T lymphocytes from human immunodeficiency virus-1-infected children
    • Debatin, K.M., Fahrig-Faissner, A., Enenkel-Stoodt, S., Kreuz, W., Benner, A. and Krammer, P.H., High Expression Of APO-1 (CD95) On T Lymphocytes From Human Immunodeficiency Virus-1-Infected Children. Blood, 83: 3101, 1994.
    • (1994) Blood , vol.83 , pp. 3101
    • Debatin, K.M.1    Fahrig-Faissner, A.2    Enenkel-Stoodt, S.3    Kreuz, W.4    Benner, A.5    Krammer, P.H.6
  • 35
    • 0029041822 scopus 로고
    • Expression of the fas antigen in patients infected with human immunodeficiency virus
    • McCloskey, T.W., Oyaizu, N., Kaplan, M. and Pahwa, S., Expression Of The Fas Antigen In Patients Infected With Human Immunodeficiency Virus. Cytometry, 22: 111, 1995.
    • (1995) Cytometry , vol.22 , pp. 111
    • McCloskey, T.W.1    Oyaizu, N.2    Kaplan, M.3    Pahwa, S.4
  • 36
    • 0029061073 scopus 로고
    • Mechanisms of apoptosis in peripheral blood mononuclear cells of HIV-infected patients
    • Oyaizu, N., McCloskey, T.W., Than, S., Hu, R. and Pahwa, S., Mechanisms Of Apoptosis In Peripheral Blood Mononuclear Cells Of HIV-Infected Patients. Adv. Exp. Med. Biol., 374: 101, 1995.
    • (1995) Adv. Exp. Med. Biol. , vol.374 , pp. 101
    • Oyaizu, N.1    McCloskey, T.W.2    Than, S.3    Hu, R.4    Pahwa, S.5
  • 37
    • 0029992895 scopus 로고    scopus 로고
    • Fas-mediated apoptosis of CD4+ and CD8+ T cells from human immunodeficiency virus-infected persons: Differential in vitro preventive effect of cytokines and protease antagonists
    • Estaquier, J., Tanaka, M., Suda, T., Nagata, S., Golstein, P. and Ameisen, J.C., Fas-Mediated Apoptosis Of CD4+ And CD8+ T Cells From Human Immunodeficiency Virus-Infected Persons: Differential In Vitro Preventive Effect Of Cytokines And Protease Antagonists. Blood, 87: 4959, 1996.
    • (1996) Blood , vol.87 , pp. 4959
    • Estaquier, J.1    Tanaka, M.2    Suda, T.3    Nagata, S.4    Golstein, P.5    Ameisen, J.C.6
  • 38
    • 0031569286 scopus 로고    scopus 로고
    • Lack of chronic immune activation in HIV-infected chimpanzees correlates with the resistance of T cells to fas/apo-1 (CD95)-induced apoptosis and preservation of a T helper 1 phenotype
    • Gougeon, M.L., Lecoeur, H., Boudet, F. et al., Lack Of Chronic Immune Activation In HIV-Infected Chimpanzees Correlates With The Resistance Of T Cells To Fas/Apo-1 (CD95)-Induced Apoptosis And Preservation Of A T Helper 1 Phenotype. J. Immunol., 158: 2964, 1997.
    • (1997) J. Immunol. , vol.158 , pp. 2964
    • Gougeon, M.L.1    Lecoeur, H.2    Boudet, F.3
  • 39
    • 9044232148 scopus 로고    scopus 로고
    • The fas receptor in HIV infection: Expression on peripheral blood lymphocytes and role in the depletion of T cells
    • Gehri, R., Hahn, S., Rothen, M., Steuerwald, M., Nuesch, R. and Erb, P., The Fas Receptor In HIV Infection: Expression On Peripheral Blood Lymphocytes And Role In The Depletion Of T Cells. AIDS, 10: 9, 1996.
    • (1996) AIDS , vol.10 , pp. 9
    • Gehri, R.1    Hahn, S.2    Rothen, M.3    Steuerwald, M.4    Nuesch, R.5    Erb, P.6
  • 40
    • 0029029058 scopus 로고
    • Sensitization of T cells to CD95-mediated apoptosis by HIV-1 tat and gp120
    • Westendorp, M.O., Frank, R., Oschsenbauer, C. et al., Sensitization Of T Cells To CD95-Mediated Apoptosis By HIV-1 Tat And gp120. Nature, 375: 497, 1995.
    • (1995) Nature , vol.375 , pp. 497
    • Westendorp, M.O.1    Frank, R.2    Oschsenbauer, C.3
  • 41
    • 0030892234 scopus 로고    scopus 로고
    • Apoptosis by death factor
    • Nagata, S., Apoptosis by death factor: Cell, 88: 355, 1997.
    • (1997) Cell , vol.88 , pp. 355
    • Nagata, S.1
  • 42
    • 0028095477 scopus 로고
    • Apoptotic signaling through CD95 (fas/apo-1) activates an acidic sphingomyelinase
    • Cifone, M.G., De Maria, R., Roncaioli, P. et al., Apoptotic Signaling Through CD95 (Fas/Apo-1) Activates An Acidic Sphingomyelinase. J. Exp. Med., 177: 1547, 1994.
    • (1994) J. Exp. Med. , vol.177 , pp. 1547
    • Cifone, M.G.1    De Maria, R.2    Roncaioli, P.3
  • 43
    • 0028790239 scopus 로고
    • Multiple pathways originate at the fas/apo-1 (CD95) receptor: Sequential involvement of phosphatidylcholine-specific phospholipase C and acidic sphingomyelinase in the propagation of the apoptotic signal
    • Cifone, M.G., Roncaioli, P., De Maria, R. et al., Multiple Pathways Originate At The Fas/Apo-1 (CD95) Receptor: Sequential Involvement Of Phosphatidylcholine-Specific Phospholipase C And Acidic Sphingomyelinase In The Propagation Of The Apoptotic Signal. EMBO J., 14: 5859, 1995.
    • (1995) EMBO J. , vol.14 , pp. 5859
    • Cifone, M.G.1    Roncaioli, P.2    De Maria, R.3
  • 44
    • 0028861429 scopus 로고
    • HIV-1 tat potentiates TNF-induced NF-kB activation and cytotoxicity by altering the cellular redox state
    • Westendorp, M.O., Shatrov, V.A., Schultze-Osthoff, K. et al., HIV-1 Tat Potentiates TNF-Induced NF-kB Activation And Cytotoxicity By Altering The Cellular Redox State. EMBO J., 14. 546, 1995.
    • (1995) EMBO J. , vol.14 , pp. 546
    • Westendorp, M.O.1    Shatrov, V.A.2    Schultze-Osthoff, K.3
  • 45
    • 0025739254 scopus 로고
    • Reactive oxygen intermediates as apparently widely used messengers in the activation of the NF-kB transcription factor and HIV-1
    • Schreck, R., Rieber, P. and Bauerle, P.A., Reactive Oxygen Intermediates As Apparently Widely Used Messengers In The Activation Of The NF-kB Transcription Factor And HIV-1. EMBO J., 10: 2247, 1991.
    • (1991) EMBO J. , vol.10 , pp. 2247
    • Schreck, R.1    Rieber, P.2    Bauerle, P.A.3
  • 46
    • 0028230429 scopus 로고
    • Oxidative stress and apoptosis in HIV infection: A role for plant-derived metabolites with synergistic antioxidant activity
    • Greenspan, H.C. and Aruoma, O.I., Oxidative Stress And Apoptosis In HIV Infection: A Role For Plant-Derived Metabolites With Synergistic Antioxidant Activity. Immunol. Today, 15: 209, 1994.
    • (1994) Immunol. Today , vol.15 , pp. 209
    • Greenspan, H.C.1    Aruoma, O.I.2
  • 47
    • 0014385564 scopus 로고
    • Isolation of mononuclear cells and granulocytes from human blood
    • Boyum, A., Isolation Of Mononuclear Cells And Granulocytes From Human Blood. Scand. J. Clin. Invest., 97 (Suppl 21): 77, 1968.
    • (1968) Scand. J. Clin. Invest. , vol.97 , Issue.SUPPL. 21 , pp. 77
    • Boyum, A.1
  • 48
    • 0025726216 scopus 로고
    • A rapid and simple method for measuring thymocyte apoptosis by propidium iodide staining and flow cytometry
    • Nicoletti, I., Migliorati, G., Pagliacci, C., Grignani, F. and Riccardi, C., A Rapid And Simple Method For Measuring Thymocyte Apoptosis By Propidium Iodide Staining And Flow Cytometry. J. Immunol. Methods, 139: 271, 1968.
    • (1968) J. Immunol. Methods , vol.139 , pp. 271
    • Nicoletti, I.1    Migliorati, G.2    Pagliacci, C.3    Grignani, F.4    Riccardi, C.5
  • 49
    • 0028295351 scopus 로고
    • A rapid method for measuring apoptosis and dual-color immunofluorescence by single laser flow cytometry
    • Schmid, I., Uittenbogaart, C.H., Keld, B. and Giorgi, J.V., A Rapid Method For Measuring Apoptosis And Dual-Color Immunofluorescence By Single Laser Flow Cytometry. J. Immunol. Methods, 170: 145, 1994.
    • (1994) J. Immunol. Methods , vol.170 , pp. 145
    • Schmid, I.1    Uittenbogaart, C.H.2    Keld, B.3    Giorgi, J.V.4
  • 50
    • 0028903933 scopus 로고
    • Reduction in mitochondrial potential constitutes an early irreversible step of programmed lymphocyte death in vivo
    • Zamzami, N., Marchetti, P., Castedo, M. et al., Reduction In Mitochondrial Potential Constitutes An Early Irreversible Step Of Programmed Lymphocyte Death In Vivo. J. Exp. Med., 181: 1661, 1995.
    • (1995) J. Exp. Med. , vol.181 , pp. 1661
    • Zamzami, N.1    Marchetti, P.2    Castedo, M.3
  • 51
    • 0025218905 scopus 로고
    • Flow cytometric analysis of respiratory burst activity in phagocytes with hydroethidine and 2', 7'-dichlorofluorescin
    • Rothe, G. and Valet, G., Flow Cytometric Analysis Of Respiratory Burst Activity In Phagocytes With Hydroethidine And 2', 7'-Dichlorofluorescin. J. Leukoc. Biol., 47: 440, 1990.
    • (1990) J. Leukoc. Biol. , vol.47 , pp. 440
    • Rothe, G.1    Valet, G.2
  • 52
    • 0021346318 scopus 로고
    • Chromatin cleavage in apoptosis: Association with condensed chromatin morphology and dependence on macromolecular synthesis
    • Wyllie, A.N., Morris, R.G., Smith, A.L. and Dunlop, D., Chromatin Cleavage In Apoptosis: Association With Condensed Chromatin Morphology And Dependence On Macromolecular Synthesis. J. Pathol., 142: 67, 1991.
    • (1991) J. Pathol. , vol.142 , pp. 67
    • Wyllie, A.N.1    Morris, R.G.2    Smith, A.L.3    Dunlop, D.4
  • 53
    • 0026543962 scopus 로고
    • Analysis and discrimination of necrosis and apoptosis (programmed cell death) by multiparameter flow cytometry
    • Dive, C., Gregory, C.D., Phipps, D.J., Evans, D.L., Milner, A.E. and Wyllie, A.H., Analysis And Discrimination Of Necrosis And Apoptosis (Programmed Cell Death) By Multiparameter Flow Cytometry. Biochim. Biophys. Acta, 1133: 275, 1992.
    • (1992) Biochim. Biophys. Acta , vol.1133 , pp. 275
    • Dive, C.1    Gregory, C.D.2    Phipps, D.J.3    Evans, D.L.4    Milner, A.E.5    Wyllie, A.H.6
  • 55
    • 0030603974 scopus 로고    scopus 로고
    • Azidothymidine induces apoptosis in mouse myeloma cell line sp2/0
    • Sailaja, G., Nayak, R. and Antony, A., Azidothymidine Induces Apoptosis In Mouse Myeloma Cell Line sp2/0. Biochem. Pharmacol., 52: 857, 1996.
    • (1996) Biochem. Pharmacol. , vol.52 , pp. 857
    • Sailaja, G.1    Nayak, R.2    Antony, A.3
  • 57
    • 0029101644 scopus 로고
    • Sequential reduction of mitochondrial transmembrane potential and generation of reactive oxygen species in early programmed cell death
    • Zamzami, N., Marchetti, P., Castedo, M. et al., Sequential Reduction Of Mitochondrial Transmembrane Potential And Generation Of Reactive Oxygen Species In early Programmed Cell Death. J. Exp. Med., 182: 367, 1995.
    • (1995) J. Exp. Med. , vol.182 , pp. 367
    • Zamzami, N.1    Marchetti, P.2    Castedo, M.3
  • 58
    • 0029036412 scopus 로고
    • Alterations of mitochondrial structure and function are early events of dexamethasone-induced thymocyte apoptosis
    • Petit, P.X., LeCoeur, H., Zorn, E., Dauguet, C., Mignotte, B. and Gougeon, M.L., Alterations Of Mitochondrial Structure And Function Are Early Events Of Dexamethasone-Induced Thymocyte Apoptosis. J. Cell. Biol., 130: 157, 1995.
    • (1995) J. Cell. Biol. , vol.130 , pp. 157
    • Petit, P.X.1    LeCoeur, H.2    Zorn, E.3    Dauguet, C.4    Mignotte, B.5    Gougeon, M.L.6
  • 59
    • 0027549721 scopus 로고
    • The resistance of HIV-infected chimpanzees to progression to AIDS correlates with absence of HIV-related dysfunction
    • Heeney, J., Jonker, J., Koornstra, W. et al., The Resistance Of HIV-Infected Chimpanzees To Progression To AIDS Correlates With Absence Of HIV-Related Dysfunction. J. Med. Primatol., 22: 194, 1993.
    • (1993) J. Med. Primatol. , vol.22 , pp. 194
    • Heeney, J.1    Jonker, J.2    Koornstra, W.3
  • 60
    • 0028074885 scopus 로고
    • Programmed cell death and AIDS: Significance of T cell apoptosis in pathogenic and nonpathogenic primate lentiviral infections
    • Estaquier, J., Idziorek, T., de Bels, F. et al., Programmed Cell Death And AIDS: Significance Of T Cell Apoptosis In Pathogenic And Nonpathogenic Primate Lentiviral Infections. Proc. Natl. Acad. Sci. USA, 91: 9341, 1994.
    • (1994) Proc. Natl. Acad. Sci. USA , vol.91 , pp. 9341
    • Estaquier, J.1    Idziorek, T.2    De Bels, F.3
  • 62
    • 0027436481 scopus 로고
    • Activation-dependent apoptosis in CD4+ T cells during murine AIDS
    • Cohen, D.A., Fitzpatrick, E.A., Barve, S.S. et al., Activation-Dependent Apoptosis In CD4+ T Cells During Murine AIDS. Cell. Immunol., 151: 392, 1993.
    • (1993) Cell. Immunol. , vol.151 , pp. 392
    • Cohen, D.A.1    Fitzpatrick, E.A.2    Barve, S.S.3
  • 63
    • 0030937655 scopus 로고    scopus 로고
    • FIV infection of the domestic cat: An animal model for AIDS
    • Willett, B.J., Flynnm J.N. and Hosie, M.J., FIV Infection Of The Domestic Cat: An Animal Model For AIDS. Immunol. Today, 18: 182, 1997.
    • (1997) Immunol. Today , vol.18 , pp. 182
    • Willett, B.J.1    Flynnm, J.N.2    Hosie, M.J.3
  • 64
    • 0013610170 scopus 로고    scopus 로고
    • Controlled trial of interleukin-2 infusions in patients infected with human immunodeficiency virus
    • Kovacs, J.A., Vogel, S., Albert, J.M. et al., Controlled Trial Of Interleukin-2 Infusions In Patients Infected With Human Immunodeficiency Virus. N. Engl. J. Med., 335: 1350, 1996.
    • (1996) N. Engl. J. Med. , vol.335 , pp. 1350
    • Kovacs, J.A.1    Vogel, S.2    Albert, J.M.3
  • 65
    • 16944364282 scopus 로고    scopus 로고
    • Subcutaneous administration of interleukin-2 in human imunodeficiency virus type 1-infected persons
    • Davey, R.T. Jr., Chaitt, D.G., Piscitelli, S.C. et al., Subcutaneous Administration Of Interleukin-2 In Human Imunodeficiency Virus Type 1-Infected Persons. J. Infect. Dis., 175: 781, 1997.
    • (1997) J. Infect. Dis. , vol.175 , pp. 781
    • Davey R.T., Jr.1    Chaitt, D.G.2    Piscitelli, S.C.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.