Antiretroviral monotherapy in early stage human immunodeficiency virus disease has no detectable effect on virus load in peripheral blood and lymph nodes

Journal of Infectious Diseases

Volumn 173, Issue 4, 1996, Pages 849-856

  Cohen, Oren J ^a   Pantaleo, Giuseppe ^c   Holodniy, Mark ^c   Fox, Cecil H ^c   Orenstein, Jan M ^c   Schnittman, Steven ^c   Niu, Manette ^b   Graziosi, Cecilia ^c   Pavlakis, George N ^c   Lalezari, Jacob ^c   Bartlett, John A ^c   Steigbigel, Roy T ^c   Cohn, Jonathan ^c   Novak, Richard ^c   McMahon, Deborah ^c   Bilello, John ^c   Fauci, Anthony S ^c  

^a NATIONAL INSTITUTE OF ALLERGY AND INFECTIOUS DISEASES   (United States)

^b CENTER FOR DRUG EVALUATION AND RESEARCH   (United States)

^c NONE

Author keywords

[No Author keywords available]

Indexed keywords

ZIDOVUDINE;

ADULT; ANTIVIRAL ACTIVITY; ARTICLE; CLINICAL ARTICLE; DRUG EFFECT; FEMALE; HUMAN; HUMAN IMMUNODEFICIENCY VIRUS; HUMAN IMMUNODEFICIENCY VIRUS INFECTION; LYMPHOCYTE COUNT; MALE; PRIORITY JOURNAL; VIREMIA; VIRUS REPLICATION;

EID: 19144363743     PISSN: 00221899     EISSN: None     Source Type: Journal    
DOI: 10.1093/infdis/173.4.849     Document Type: Article

References (5)

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2. Fischl M, Richman D, Hansen N, et al. The safety and efficacy of zidovudine (AZT) in the treatment of subjects with mildly symptomatic human immunodeficiency virus type l (HIV) infection. A double-blind, placebo-controlled trial. Ann Intern Med 1990;112:727-37.
3. Volberding P, Lagakos S, Koch M, et al. Zidovudine in asymptomatic human immunodeficiency virus infection. A controlled trial in persons with fewer than 500 CD4-positive cells per cubic millimeter. N Engl J Med 1990;322:941-9.
4. Volberding P, Lagakos S, Grimes J, et al. The duration of zidovudine benefit in persons with asymptomatic HIV infection. JAMA 1994;272:437-42.
5. Vella S, Giuliano M, Dally L, et al. Long-term follow-up of zidovudine therapy in asymptomatic HIV infection: results of a multicenter cohort study. J Acquir Immune Defic Syndr 1994;7:31-8.