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Volumn 460, Issue 2, 1999, Pages 235-240

Combination of the novel farnesyltransferase inhibitor RPR130401 and the geranylgeranyltransferase-1 inhibitor GGTI-298 disrupts MAP kinase activation and G1-S transition in Ki-Ras-overexpressing transformed adrenocortical cells

Author keywords

Alternative pathway; Anti proliferative effect; Farnesyltransferase; Geranylgeranyltransferase; Kirsten Ras; Prenylation

Indexed keywords

GERANYLTRANSFERASE; GGTI 298; MEVINOLIN; MITOGEN ACTIVATED PROTEIN KINASE; N [[5 [(2 AMINO 3 MERCAPTOPROPYL)AMINO][1,1' BIPHENYL] 2 YL]CARBONYL]METHIONINE METHYL ESTER; PROTEIN FARNESYLTRANSFERASE INHIBITOR; RPR 13041; SIMVASTATIN; TRANSFERASE INHIBITOR; UNCLASSIFIED DRUG;

EID: 0032752610     PISSN: 00145793     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0014-5793(99)01355-1     Document Type: Article
Times cited : (23)

References (29)


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.