Mechanism of inhibition of P-glycoprotein-mediated drug transport by protein kinase C blockers

Biochemical Pharmacology

Volumn 58, Issue 11, 1999, Pages 1723-1733

  Castro, Ariel F ^a   Horton, Julie K ^a   Vanoye, Carlos G ^a   Altenberg, Guillermo A ^a  

^a UNIVERSITY OF TEXAS MEDICAL BRANCH   (United States)

Author keywords

ABC proteins; Chelerythrine; MDR1; Multidrug resistance; Phosphorylation; Safingol

Indexed keywords

ABC TRANSPORTER; AZIDOPINE; CALCEIN; CALPHOSTIN; CHELERYTHRINE; GLYCOPROTEIN P; PROTEIN KINASE C INHIBITOR; SAFINGOL; STAUROSPORINE; VINBLASTINE;

ANIMAL CELL; ARTICLE; BINDING COMPETITION; CANCER CELL CULTURE; CONTROLLED STUDY; DRUG ACCUMULATION; DRUG MECHANISM; DRUG PROTEIN BINDING; DRUG TRANSPORT; ENZYME INHIBITION; HUMAN; HUMAN CELL; MULTIDRUG RESISTANCE; NONHUMAN; PHOTOAFFINITY LABELING; PRIORITY JOURNAL; PROTEIN PHOSPHORYLATION; SIGNAL TRANSDUCTION;

3T3 CELLS; AFFINITY LABELS; ANIMALS; AZIDES; BIOLOGICAL TRANSPORT; DIHYDROPYRIDINES; ENZYME INHIBITORS; HUMANS; MICE; P-GLYCOPROTEIN; PHOSPHORYLATION; PROTEIN KINASE C; SIGNAL TRANSDUCTION; SPHINGOSINE; TUMOR CELLS, CULTURED;

EID: 0032750335     PISSN: 00062952     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0006-2952(99)00288-9     Document Type: Article

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