Role of interleukin-8 phosphorylated kinases in stimulating neutrophil migration through fibrin gels

Laboratory Investigation

Volumn 79, Issue 11, 1999, Pages 1403-1413

  Schnyder, Bruno ^a,b   Bogdan Jr , John A ^a   Schnyder Candrian, Silvia ^c  

^a DUPONT COMPANY   (United States)

^b UNIVERSITY OF FRIBOURG   (Switzerland)

^c THOMAS JEFFERSON UNIVERSITY   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

2 (2 AMINO 3 METHOXYPHENYL)CHROMONE; 6 (4 FLUOROPHENYL) 2,3 DIHYDRO 5 (4 METHOXYPHENYL)IMIDAZO[2,1 B]THIAZOLE 1 OXIDE; FIBRIN; IMIDAZOLE DERIVATIVE; INTERLEUKIN 8; LEUKOTRIENE B4; MITOGEN ACTIVATED PROTEIN KINASE; N [1 (1,3 BENZODIOXOL 5 YL)BUTYL] 3,3 DIETHYL 2 [4 [(4 METHYL 1 PIPERAZINYL)CARBONYL]PHENOXY] 4 OXO 1 AZETIDINECARBOXAMIDE; PHOSPHATIDYLINOSITOL 3 KINASE; SUPEROXIDE; WORTMANNIN;

ARTICLE; CELL MIGRATION; CELL STIMULATION; CONTROLLED STUDY; ENZYME ACTIVITY; ENZYME PHOSPHORYLATION; HUMAN; INFLAMMATION; NEUTROPHIL; NORMAL HUMAN; PRIORITY JOURNAL; RESPIRATORY BURST;

CELL MOVEMENT; FIBRIN; GELS; HUMANS; INTERLEUKIN-8; MITOGEN-ACTIVATED PROTEIN KINASE 1; MITOGEN-ACTIVATED PROTEIN KINASE 3; MITOGEN-ACTIVATED PROTEIN KINASES; NEUTROPHILS; P38 MITOGEN-ACTIVATED PROTEIN KINASES; PHOSPHORYLATION; RESPIRATORY BURST;

EID: 0032734795     PISSN: 00236837     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

References (46)

1. Barna JB and Kew RR (1995). Inhibition of neutrophil chemotaxis by protease inhibitors: Differential effect of inhibitors of serine and thiol proteases. Inflammation 19:561-574.
2. Belaaouaj A, McCarthy R, Baumann M, Gao Z, Ley TJ, Abraham SN, and Shapiro SD (1998). Mice lacking neutrophil elastase reveal impaired host defense against gram negative bacterial sepsis. Nat Med 4:615-618.
3. Bondeva T, Pirola L, Bulgarelli-Leva G, Rubio I, Wetzker R, and Wymann MP (1998). Bifurcation of lipid and protein kinase signals of PI3Kgamma to the protein kinases PKB and MAPK. Science 282:293-296.
4. Ciano PS, Colvin RB, Dvorak AM, McDonagh J, and Dvorak HF (1986). Macrophage migration in fibrin gel matrices. Lab Invest 54:62-70.
5. Colditz IG and Watson DL (1992). The effect of cytokines and chemotactic agonists on the migration of T lymphocytes into skin. Immunology 76:272-278.
6. DeSilva DR, Jones EA, Favata MF, Jaffee BD, Magolda RL, Trzaskos JM, and Scherle PA (1998). Inhibition of mitogen-activated protein kinase kinase blocks T cell proliferation but does not induce or prevent anergy. J Immunol 160:4175-4181.
7. Ding A, Chen B, Fuortes M, and Blum E (1996). Association of mitogen-activated protein kinases with microtubules in mouse macrophages. J Exp Med 183:1899-1904.
8. Doherty JB, Shah SK, Finke PE, Dorn CPJ, Hagmann WK, Hale JJ, Kissinger AL, Thompson KR, Brause K, and Chandler GO (1993). Chemical, biochemical, pharmacokinetic, and biological properties of L-680,833: A potent, orally active monocyclic beta-lactam inhibitor of human polymorphonuclear leukocyte elastase. Proc Natl Acad Sci 90:8727-8731.
9. Dudley DT, Pang L, Decker SJ, Bridges AJ, and Saltiel AR (1995). A synthetic inhibitor of the mitogen-activated protein kinase cascade. Proc Natl Acad Sci USA 92:7686-7689.
10. El Benna J, Faust LP, Johnson JL, and Babior BM (1996). Phosphorylation of the respiratory burst oxidase subunit p47phox as determined by two-dimensional phosphopeptide mapping: Phosphorylation by protein kinase C, Protein kinase A, and a mitogen-activated protein kinase. J Biol Chem 271:6374-6378.
11. Favata MF, Horiuchi KY, Manos EJ, Daulerio AJ, Stradley DA, Feeser WS, Van Dyk DE, Pitts WJ, Earl RA, Hobbs F, Copeland RA, Magolda RL, Scherle PA, and Trzaskos JM (1998). Identification of a novel inhibitor of mitogen-activated protein kinase kinase. J Biol Chem 273:18623-18632.
12. Gharaee-Kermani M, Wiggins R, Wolber F, Goyal M, and Phan SH (1996). Fibronectin is the major fibroblast chemoattractant in rabbit anti-glomerular basement membrane disease. Am J Pathol 148:961-967.
13. Griswold DE, Hoffstein S, Marshall PJ, Webb EF, Hillegass L, Bender PE, and Hanna N (1989). Inhibition of inflammatory cell infiltration by bicyclic imidazoles, SK&F 86002 and SK&F 104493. Inflammation 13:727-739.
14. Hannigan M, Zhan L, Ai Y, and Huang C-K (1998). The role of p38 MAP kinase in TGF-β induced signal transduction in human neutrophils. Biochem Biophys Res Commun 246:55-58.
15. Henke CA, Roongta U, Mickelson DJ, Knutson JR, and McCarthy JB (1997). CD44-related chondroitin sulfate proteoglycan, a cell surface receptor implicated with tumor cell invasion, mediates endothelial cell migration on fibrinogen and invasion into a fibrin matrix. J Clin Invest 97:2541-2552.
16. Huang C-K, Zhan L, Ai Y, and Jongstra J (1997). LSP1 is the major substrate for mitogen-activated protein kinase-activated protein kinase 2 in human neutrophils. J Biol Chem 272:17-19.
17. Huot J, Houle F, Marceau F, and Landry J (1997). Oxidative stress-induced actin reorganization mediated by the p38 mitogen-activated protein kinase/heat shock protein 27 pathway in vascular endothelial cells. Circ Res 80:383-392.
18. Jiang Y, Gram H, Zhao M, New L, Gu J, Feng L, DiPadova F, Ulevitch RJ, and Han J (1997). Characterization of the structure and function of the fourth member of p38 group mitogen-activated protein kinases, p38 delta. J Biol Chem 272:30122-30128.
19. Keely PJ, Westwick JK, Whitehead IP, Der CJ, and Parise LV (1997). Cdc42 and Rac1 induce integrin-mediated cell motility and invasiveness through PI(3)K. Nature 390:632-636.
20. Kitchen E, Rossi AG, Condliffe AM, Haslett C, and Chilvers ER (1996). Demonstration of reversible priming of human neutrophils using platelet-activating factor. Blood 88:4330-4337.
21. Klemke RL, Cai S, Giannini AL, Gallagher PJ, deLanerolle P, and Cheresh DA (1997). Regulation of cell motility by mitogen-activated protein kinase. J Cell Biol 137:481-492.
22. Knall C, Worthen GS, and Johnson GL (1997). Interleukin 8-stimulated phosphatidylinositol-3-kinase activity regulates the migration of human neutrophils independent of extracellular signal-regulated kinase and p38 mitogen-activated protein kinases. Proc Natl Acad Sci 94:3052-3057.
23. Kuroki M and O'Flaherty JT (1997). Differential effects of a mitogen-activated protein kinase kinase inhibitor on human neutrophil responses to chemotactic factors. Biochem Biophys Res Commun 232:474-477.
24. Lee JC, Badger AM, Griswold DE, Dunnington D, Truneh A, Votta B, White JR, Young PR, and Bender PE (1993). Bicyclic imidazoles as a novel class of cytokine biosynthesis inhibitors. Ann NY Acad Sci 696:149-170.
25. Lee JC, Laydon JT, McDonnell PC, Gallagher TF, Kumar S, Green D, McNulty D, Blumenthal MJ, Heys JR, and Landvatter SW (1994). A protein kinase involved in the regulation of inflammatory cytokine biosynthesis. Nature 372:739-746.
26. Loike JD, Khoury J, Cao L, Richards CP, Rascoff H, Mandeville JT, Maxfield FR, and Silverstein SC (1995). Fibrin regulates neutrophil migration in response to interleukin 8, leukotriene B4, tumor necrosis factor, and formyl-methionylleucyl-phenylalanine. J Exp Med 181:1763-1772.
27. Mandeville JTH, Lawson MA, and Maxfield FR (1997). Dynamic imaging of neutrophil migration in three dimensions: Mechanical interactions between cells and matrix. J Leukoc Biol 61:188-200.
28. Metzner B, Heger M, Hofmann C, Czech W, and Norgauer J (1997). Evidence for the involvement of phosphatidylinositol 4:5-biphosphate 3-kinase in CD18-mediated adhesion of human neutrophils to fibrinogen. Biochem Biophys Res Commun 232:719-723.
29. Mizgerd JP, Kubo H, Kutkoski GJ, Bhagwan SD, Scharffetter-Kochanek K, Beaudet AL, and Doerschuk CM (1997). Neutrophil emigration in the skin, lungs, and peritoneum: Different requirements for CD11/CD18 revealed by CD18-deficient mice. J Exp Med 186:1357-1364.
30. Nick JA, Avdi NJ, Young SK, Knall C, Gerwins P, Johnson GL, and Worthen GS (1997). Common and distinct intracellular signaling pathways in human neutrophils utilized by platelet activating factor and FMLP. J Clin Invest 99:975-986.
31. Nick JA, Avdi NJ, Young SK, Knall C, Lehman LA, McDonald PP, Frasch SC, Billstrom MA, Henson PM, Johnson GL, and Worthen GS (1999). Selective activation and functional significance of p38a mitogen-activated protein kinase in lipopolysaccharide-stimulated neutrophils. J Clin Invest 103: 851-858.
32. Raingeaud J, Gupta S, Rogers JS, Dickens M, Han J, Ulevitch RJ, and Davis RJ (1995). Pro-inflammatory cytokines and environmental stress cause p38 mitogen-activated protein kinase activation by dual phosphorylation on tyrosine and threonine. J Biol Chem 270:7420-7426.
33. Reszka AA, Seger R, Diltz CD, Krebs EG, and Fischer EH (1995). Association of mitogen-activated protein kinase with the microtubule cytoskeleton. Proc Natl Acad Sci USA 92: 8881-8885.
34. Rieder G, Hatz RA, Moran AP, Walz A, Stolte M, and Enders G (1998). Role of adherence in interleukin-8 induction in Helicobacter pylori-associated gastritis. Infect Immun 65: 3622-3630.
35. Schmalstieg FC, Rudloff HE, Hillman GR, and Anderson DC (1986). Two-dimensional and three-dimensional movement of human polymorphonuclear leukocytes: Two fundamentally different mechanisms of location. J Leukoc Biol 40:677-691.
36. Schnyder B, Lahm H, Woerly G, Odartchenko N, Ryffel B, and Car BD (1996a). Growth inhibition signalled through the interleukin-4/interleukin-13 receptor complex is associated with tyrosine phosphorylation of insulin receptor substrate-1. Biochem J 315:767-774.
37. Schnyder B, Lugli S, Feng N, Euer H, Lutz RA, Ryffel B, Sugamura K, Wunderli-Allenspach H, and Moser R (1996b). Interleukin-4 (IL-4) and IL-13 bind to a shared heterodimeric complex on endothelial cells mediating vascular cell adhesion molecule-1 induction in the absence of the common gamma chain. Blood 87:4286-4295.
38. Schnyder-Candrian S, Strieter RM, Kunkel SL, and Walz A (1995). Interferon-α and interferon-γ down-regulate the production of interleukin-8 and ENA-78 in human monocytes. J Leukoc Biol 57:929-934.
39. Schnyder-Candrian S and Walz A (1997). Neutrophil-activating protein ENA-78 and IL-8 exhibit different patterns of expression in lipopolysaccharide- and cytokine-stimulated human monocytes. J Immunol 158:3888-3894.
40. Sebolt-Leopold JS, Dudley DT, Herrera R, Van Becelaere K, Wiland A, Gowan RC, Tecle H, Barrett SD, Bridges A, Przybranowski S, Leopold WR, Saltiel AR (1999). Blockade of the MAP kinase pathway suppresses growth of colon tumors in vivo. Nat Med 5:810-816.
41. Sutherland CL, Heath AW, Pelech SL, Young PR, and Gold MR (1996). Differential activation of the ERK, JNK, and p38 mitogen-activated protein kinases by CD40 and the B cell antigen receptor. J Immunol 157:3381-3390.
42. Thelen M, Uguccioni M, and Bosiger J (1995). PI 3-kinase-dependent and independent chemotaxis of human neutrophil leukocytes. Biochem Biophys Res Commun 217:1255-1262.
43. Thelen M, Wymann MP, and Langen H (1994). Wortmannin binds specifically to 1-phosphatidylinositol 3-kinase while inhibiting guanine nucleotide-binding protein-coupled receptor signaling in neutrophil leukocytes. Proc Natl Acad Sci 91:4960-4964.
44. Yokomizo T, Izumi T, Chang K, Takuwa Y, and Shimizu T (1997). A G-protein-coupled receptor for leukotriene B4 that mediates chemotaxis. Nature 387:620-624.
45. Young PR, McLaughlin MM, Kumar S, Kassis S, Doyle ML, NcNulty DGT, Fisher S, NcDonnell PC, Carr SA, Huddleston MJ, Seibel G, Porter TG, Livi GP, Adams JL, and Lee JC (1997). Pyridinyl imidazole inhibitors of p38 mitogen-activated protein kinase bind in the ATP site. J Biol Chem 272:12116-12122.
46. Zu YL, Qi J, Gilchrist A, Fernandez GA, Vasquez-Abad D, Kreutzer DL, Huang C-K, and Sha'afi RI (1998). p38 mitogen-activated protein kinase activation is required for human neutrophil function triggered by JNF-α or fMLP stimulation. J Immunol 160:1982-1989.