CD44-related chondroitin sulfate proteoglycan, a cell surface receptor implicated with tumor cell invasion, mediates endothelial cell migration on fibrinogen and invasion into a fibrin matrix

Journal of Clinical Investigation

Volumn 97, Issue 11, 1996, Pages 2541-2552

  Henke, Craig A ^a   Roongta, Urvashi ^a   Mickelson, Daniel J ^a   Knutson, Jennifer R ^a   McCarthy, James B ^a  

^a UNIVERSITY OF MINNESOTA MEDICAL SCHOOL   (United States)

Author keywords

angiogenesis; CD44 related chondroitin sulfate proteoglycan; cell movement; cell surface receptor; wound healing

Indexed keywords

CELL SURFACE RECEPTOR; CHONDROITIN ABC LYASE; FIBRIN; FIBRINOGEN; HERMES ANTIGEN; MONOCLONAL ANTIBODY; PROTEOCHONDROITIN SULFATE; PROTEOGLYCAN; PYRANOSIDE;

AFFINITY CHROMATOGRAPHY; ANIMAL CELL; ANION EXCHANGE CHROMATOGRAPHY; ARTICLE; CELL ADHESION; CELL CULTURE; CELL INVASION; CELL MIGRATION; ENDOTHELIUM CELL; EXTRACTION; IMMUNOBLOTTING; IMMUNOPRECIPITATION; ISOTOPE LABELING; NONHUMAN; POLYACRYLAMIDE GEL ELECTROPHORESIS; PRIORITY JOURNAL; RABBIT; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; WOUND HEALING;

EID: 0029949785     PISSN: 00219738     EISSN: None     Source Type: Journal    
DOI: 10.1172/JCI118702     Document Type: Article

References (46)

1. Brown, L.F., A.M. Dvorak, and H.F. Dvorak. 1989. Leaky vessels, fibrin deposition, and fibrosis: a sequence of events common to solid tumors and to many other types of disease. Am. Rev. Respir. Dis. 140:1104-1107.
2. Henke, C., V. Regel, M. Peterson, M. Wick, D. Knighton, J. McCarthy, and P. Bitterman. 1991. Identification and partial characterization of angiogenesis bioactivity in the lower respiratory tract after acute lung injury. J. Clin. Invest. 88:1386-1395.
3. Henke, C., W. Marinelli, J. Jessurun, J. Fox, D. Harms, M. Peterson, L. Chiang, and P. Doran. 1993. Macrophage production of basic fibroblast growth factor in the fibroproliferative disorder of alveolar fibrosis after lung injury. Am. J. Pathol. 143:1189-1199.
4. Dvorak, H.F., V.S. Harvey, P. Estrella, L.F. Brown, J. McDonagh, and A.M. Dvorak. 1987. Fibrin containing gels induce angiogenesis. Implications of tumor stroma generation and wound healing. Lab. Invest. 57:673-686.
5. Brown, L.F., N. Lanir, J. McDonagh, K. Tognazzi, A.M. Dvorak, and H.F. Dvorak. 1993. Fibroblast migration in fibrin gel matrices. Am. J. Pathol. 142:273-283.
6. Cheresh, D.A. 1987. Human endothelial cells synthesize and express an Arg-Gly-Asp-directed adhesion receptor involved in attachment of fibrinogen and von Willebrand factor. Proc. Natl. Acad. Sci. USA. 84:6471-6475.
7. Charo, I.F., L.S. Bekeart, and D.R. Phillips. 1987. Platelet glycoprotein IIb-IIIa-like proteins mediate endothelial cell attachment to adhesive proteins and the extracellular matrix. J. Biol. Chem. 262:9935-9938.
8. Dejana, E., L.R. Languino, S. Colella, G.C. Corbascio, E. Plow, M. Ginsberg, and P.C. Marchisio. 1988. The localization of a platelet GpIIb-IIIa-related protein in endothelial cell adhesion structures. Blood. 71:566-572.
9. Cheresh, D.A., S.A. Berliner, V. Vicente, and Z.M. Ruggeri. 1989. Recognition of distinct adhesive sites on fibrinogen by related integrins on platelets and endothelial cells. Cell. 58:945-953.
10. Augustin-Voss, H.G., and B.U. Pauli. 1992. Migrating endothelial cells are distinctly hyperglycosylated and express specific migration-associated cell surface glycoproteins. J. Cell Biol. 119:483-491.
11. Kinsella, M.G., and T.N. Wight. 1986. Modulation of sulfated proteoglycan synthesis by bovine aortic endothelial cells during migration. J. Cell Biol. 102:679-687.
12. Garrigues, H.J., M.W. Lark, S. Lara, I. Hellstrom, K.E. Hellstrom, and T.N. Wight. 1986. The melanoma proteoglycan: restricted expression on microspikes, a specific microdomain of the cell surface. J. Cell Biol. 103:1699-1710.
13. Faassen, A.E., J.A. Schrager, D.J. Klein, T.R. Oegema, J.R. Couchman, and J.B. McCarthy. 1992. A cell surface chondroitin sulfate proteoglycan, immunologically related to CD44, is involved in type I collagen-mediated melanoma cell motility and invasion. J. Cell Biol. 116:521-531.
14. Kalomiris, E.L., and L.Y.W. Bourguignon. 1988. Mouse T lymphoma cells contain a transmembrane glycoprotein (gp85) that binds ankyrin. J. Cell Biol. 106:316-327.
15. Lokeshwar, V.B., and L.Y.W. Bourguignon. 1992. The lymphoma transmembrane glycoprotein gp85 (CD44) is a novel guanine nucleotide-binding protein which regulates gp85 (CD44)-ankyrin interaction. J. Biol. Chem. 267: 22073-22078.
16. Jacobson, K., D. O'dell, B. Holifield, T.L. Murphy, and J.T. August. 1984. Redistribution of a major cell surface glycoprotein during cell movement. J. Cell Biol. 99:1613-1623.
17. Underhill, C. 1992. CD44: the hyaluronan receptor. J. Cell. Sci. 103:293-298.
18. Peach, R.J., D. Hollenbaugh, I. Stamenkovic, and A. Aruffo. 1993. Identification of hyaluronic acid binding sites in the extracellular domain of CD44. J. Cell Biol. 122:257-264.
19. Jalkanen, S., M. Jalkanen, R. Bargatze, M. Tammi, and E.C. Butcher. 1988. Biochemical properties of glycoproteins involved in lymphocyte recognition of high endothelial venules in man. J. Immunol. 141:1615-1623.
20. Stamenkovic, I., M. Amiot, J.M. Pesando, and B. Seed. 1989. A lymphocyte molecule implicated in lymph node homing is a member of the cartilage link protein family. Cell. 56:1057-1062.
21. Goldstein, L.A., D.F.H. Zhou, L.J. Picker, C.N. Minty, R.F. Bargatze, J.F. Ding, and E.C. Butcher. 1990. A human lymphocyte homing receptor, the Hermes antigen, is related to cartilage proteoglycan core and link proteins. Cell. 56:1063-1072.
22. Thomas, L., R. Byers, J. Vink, and I. Stamenkovic. 1992. CD44H regulates tumor cell migration on hyaluronate-coated substrate. J. Cell Biol. 118: 971-977.
23. Gunthert, U., M. Hofmann, W. Rudy, S. Reber, M. Zoller, I. Baußmann, S. Matzku, A. Wenzel, H. Ponta, and P. Herrlich. 1991. A new variant of glycoprotein CD44 confers metastatic potential to rat carcinoma cells. Cell. 65: 13-24.
24. Rudy, W., M. Hofmann, R. Schwartz-Albiez, M. Zoller, K.H. Heider, H. Ponta, and P. Herrlich. 1993. The two major CD44 proteins expressed on a metastatic rat tumor cell line are derived from different splice variants: each one individually suffices to confer metastatic behavior. Cancer Res. 53:1262-1268.
25. Sy, M.S., Y.J. Guo, and I. Stamenkovic. 1991. Distinct effects of two CD44 isoforms on tumor growth in vivo. J. Exp. Med. 174:859-866.
26. Schwartz, N.B. 1977. Regulation of chondroitin sulfate synthesis. J. Biol. Chem. 252:6316-6321.
27. McCarthy, J.B., S.T. Hagen, and L.T. Furcht. 1986. Human fibronectin contains distinct adhesion-and motility-promoting domains for metastatic melanoma cells. J. Cell Biol. 102:179-188.
28. 4. Nature (Lond.). 227:680-685.
29. Bennett, K.L., D.G. Jackson, J.C. Simon, E. Tanczos, R. Peach, B. Modrell, I. Stamenkovic, G. Plowman, and A. Aruffo. 1995. CD44 isoforms containing exon V3 are responsible for the presentation of heparin-binding growth factor. J. Cell Biol. 128:687-698.
30. van Weering, D.H.J., P.D. Baas, and J.L. Bos. 1993. A PCR-based method for the analysis of human CD44 splice products. PCR Methods Appl. 3: 100-106.
31. Screaton, G.R., M.V. Bell, D.G. Jackson, F.B. Cornelis, U. Gerth, and J.I Bell. 1992. Genomic structure of DNA encoding the lymphocyte homing receptor CD44 reveals at least 12 alternately splice exons. Proc. Natl. Acad. Sci. USA. 89:12169-12164.
32. Yeo, T-K., L. Brown, and H.F. Dvorak. 1991. Alterations in proleoglycan synthesis common to healing wounds and tumors. Am. J. Pathol. 138:1437-1450.
33. Gross, J.L., D. Moscatelli, and D. Rifkin. 1983. Increased capillary endothelial cell protease activity in response to angiogenic stimuli in vitro. Proc. Natl. Acad. Sci. USA. 80:2623-2727.
34. Moscatelli, D., M. Presta, and D. Rifkin. 1986. Purification of a factor from human placenta that stimulates capillary endothelial cell protease production, DNA synthesis and migration. Proc. Natl. Acad. Sci. USA. 83:2091-2095.
35. Banda, M.J., G.S. Herron, G. Murphy, Z. Werb, and K.S. Dwyer. 1988. Proteinase induction by endothelial cells during wound repair. In Growth Factors and Other Aspects of Wound Healing: Biological and Clinical Implications: Proceedings of the Second International Symposium on Tissue Repair, Held at the Innisbrook Resort, Tarpon Springs, Florida, May 13-17, 1987. Adrian Barbul, editor. Alan R. Liss, Inc., New York. 117-130.
36. Montesano, R., M.S. Pepper, U. Mohle-Steinlein, W. Risau, E.F. Wagner, and L. Orci. 1990. Increased proteolytic activity is responsible for the aberrant morphogenetic behavior of endothelial cells expressing the middle T oncogene. Cell. 62:435-445.
37. Howard, P.S., J.C. Myers, S.F. Gorfein, and E.J. Macarak. 1991. Progressive modulation of endothelial cell phenotype during in vitro blood vessel formation. Dev. Biol. 146:325-338.
38. Montesano, R., and L. Orci. 1987. Phorbol esters induce angiogenesis in vitro from large vessel endothelial cells. J. Cell. Physiol. 130:284-291.
39. Aruffo, A., I. Stamenkovic, M. Melnick, C.B. Underhill, and B. Seed. 1990. CD44 is the principal cell surface receptor for hyaluronate. Cell. 61:1303-1313.
40. Jalkanen, S., and M. Jalkanen. 1992. Lymphocyte CD44 Binds the COOH-terminal heparin-binding domain of fibronectin. J. Cell Biol. 116:817-825.
41. Wayner, E.A., and W.G. Carter. 1987. Identification of multiple cell adhesion receptors for collagen and fibronectin in human fibrosarcoma cells possessing unique α and common β subunits. J. Cell Biol. 105:1873-1884.
42. St. John, T., J. Meyer, R. Idzerda, and W.M. Gallatin. 1990. Expression of CD44 confers a new adhesive phenotype on transfected cells. Cell. 60:45-52.
43. Tarone, G., R. Ferracini, G. Galetto, and P. Comoglio. 1984. A cell surface integral membrane glycoprotein of 85,000 mol wt (gp85) associated with Triton X-100-insoluble cell skeleton. J. Cell Biol. 99:512-519.
44. Lacy, B.E., and C.B. Underhill. 1987. The hyaluronate receptor is associated with actin filaments. J. Cell Biol. 105:1395-1404.
45. 1 integrin in mediating melanoma cell adhesion to fibronectin. J. Cell Biol. 118: 431-444.
46. Canfield, A.E., A.B. Sutton, D.R. Hiscock, J.T. Gallagher, and A.M. Schor. 1994. Alpha- and beta-xylosides modulate the synthesis of fibronectin and thrombospondin-1 by endothelial cells. Biochem. Biophys. Acta. 1200:249-258.