메뉴 건너뛰기




Volumn 23, Issue 1, 1999, Pages 13-20

Effects of cAMP on ERK mitogen-activated protein kinase activity in hepatocytes do not parallel the bidirectional regulation of DNA synthesis

Author keywords

cAMP; DNA synthesis; EGF; ERK; Hepatocyte; MAP kinase

Indexed keywords

8 (4 CHLOROPHENYLTHIO) CYCLIC AMP; CYCLIC AMP; GLUCAGON; MITOGEN ACTIVATED PROTEIN KINASE;

EID: 0032727131     PISSN: 10656995     EISSN: None     Source Type: Journal    
DOI: 10.1006/cbir.1998.0314     Document Type: Article
Times cited : (9)

References (60)
  • 1
    • 0025895762 scopus 로고
    • Activation of mitogen-activated protein kinase in BC3H1 myocytes by fluoroaluminate
    • Anderson N.G., Kilgour E., Sturgill T.W. Activation of mitogen-activated protein kinase in BC3H1 myocytes by fluoroaluminate. J Biol Chem. 266:1991;10,131-10,135.
    • (1991) J Biol Chem , vol.266 , pp. 10131-10135
    • Anderson, N.G.1    Kilgour, E.2    Sturgill, T.W.3
  • 2
    • 0028791019 scopus 로고
    • Intercellular heterogeneity of early mitogenic events: CAMP generalizes the EGF effect on c-Fos protein appearance but not on MAP kinase phosphorylation and nuclear translocation in dog thyroid epithelial cells
    • Baptist M., Dumont J.E., Roger P.P. Intercellular heterogeneity of early mitogenic events: cAMP generalizes the EGF effect on c-Fos protein appearance but not on MAP kinase phosphorylation and nuclear translocation in dog thyroid epithelial cells. Exp Cell Res. 221:1995;160-171.
    • (1995) Exp Cell Res , vol.221 , pp. 160-171
    • Baptist, M.1    Dumont, J.E.2    Roger, P.P.3
  • 3
    • 0031052218 scopus 로고    scopus 로고
    • 8-Bromo-cAMP induces a proliferative response in an IL-3 dependent leukemic cell line and activates Erk1,2 via a Shc-independent pathway
    • Barge R.M.Y., Falkenburg J.H.F., Willemze R., Maassen J.A. 8-Bromo-cAMP induces a proliferative response in an IL-3 dependent leukemic cell line and activates Erk1,2 via a Shc-independent pathway. Biochim Biophys Acta. 1355:1997;141-146.
    • (1997) Biochim Biophys Acta , vol.1355 , pp. 141-146
    • Barge, R.M.Y.1    Falkenburg, J.H.F.2    Willemze, R.3    Maassen, J.A.4
  • 4
    • 0014645531 scopus 로고
    • High-yield preparation of isolated rat liver parenchymal cells
    • Berry N.M., Friend D.S. High-yield preparation of isolated rat liver parenchymal cells. J Cell Biol. 43:1969;506-520.
    • (1969) J Cell Biol , vol.43 , pp. 506-520
    • Berry, N.M.1    Friend, D.S.2
  • 5
    • 0028566860 scopus 로고
    • In vitro and in vivo regulation of hepatic mitogen-activated protein kinases in fetal rats
    • Boylan J.M., Gruppuso P.A. In vitro and in vivo regulation of hepatic mitogen-activated protein kinases in fetal rats. Am J Physiol. 267:1994;G1078-G1086.
    • (1994) Am J Physiol , vol.267
    • Boylan, J.M.1    Gruppuso, P.A.2
  • 6
    • 0000688489 scopus 로고
    • The role of cyclic AMP in cell proliferation: A critical assessment of the evidence
    • Boynton A.L., Whitfield J.F. The role of cyclic AMP in cell proliferation: a critical assessment of the evidence. Adv Cyclic Nucleotide Res. 15:1983;193-294.
    • (1983) Adv Cyclic Nucleotide Res , vol.15 , pp. 193-294
    • Boynton, A.L.1    Whitfield, J.F.2
  • 7
    • 0020529062 scopus 로고
    • Bidirectional concentration-dependent effects of glucagon and dibutyryl cyclic AMP on DNA synthesis in cultured adult rat hepatocytes
    • Brønstad G.O., Sand T-E, Christoffersen T. Bidirectional concentration-dependent effects of glucagon and dibutyryl cyclic AMP on DNA synthesis in cultured adult rat hepatocytes. Biochim Biophys Acta. 763:1983;58-63.
    • (1983) Biochim Biophys Acta , vol.763 , pp. 58-63
    • Brønstad, G.O.1    Sand, T.-E.2    Christoffersen, T.3
  • 8
    • 0016732660 scopus 로고
    • Regulation of hepatic regeneration in rats by synergistic action of insulin and glucagon
    • Bucher N.L.R., Swaffield M.N. Regulation of hepatic regeneration in rats by synergistic action of insulin and glucagon. Proc Natl Acad Sci U S A. 72:1975;1157-1160.
    • (1975) Proc Natl Acad Sci U S A , vol.72 , pp. 1157-1160
    • Bucher, N.L.R.1    Swaffield, M.N.2
  • 9
    • 0028917954 scopus 로고
    • Regulation of Ras-mediated signalling: More than one way to skin a cat
    • Burgering B.M.T., Bos J.L. Regulation of Ras-mediated signalling: more than one way to skin a cat. Trends Biochem Sci. 20:1995;18-22.
    • (1995) Trends Biochem Sci , vol.20 , pp. 18-22
    • Burgering, B.M.T.1    Bos, J.L.2
  • 11
    • 0021321478 scopus 로고
    • Changes in hormone responsiveness and cyclic AMP metabolism in rat hepatocytes during primary culture and effects of supplementing the medium with insulin and dexamethasone
    • Christoffersen T., Refsnes M., Brønstad G.O., Østby E., Huse J., Haffner F., Sand T-E, Hunt N.H., Sonne O. Changes in hormone responsiveness and cyclic AMP metabolism in rat hepatocytes during primary culture and effects of supplementing the medium with insulin and dexamethasone. Eur J Biochem. 138:1984;217-226.
    • (1984) Eur J Biochem , vol.138 , pp. 217-226
    • Christoffersen, T.1    Refsnes, M.2    Brønstad, G.O.3    Østby, E.4    Huse, J.5    Haffner, F.6    Sand, T.-E.7    Hunt, N.H.8    Sonne, O.9
  • 12
    • 0028330527 scopus 로고
    • Retinoblastoma protein is rapidly dephosphorylated by elevated cyclic adenosine monophosphate levels in human B-lymphoid cells
    • Christoffersen J., Smeland E.B., Stokke T., Taskén K., Andersson K.B., Blomhoff H.K. Retinoblastoma protein is rapidly dephosphorylated by elevated cyclic adenosine monophosphate levels in human B-lymphoid cells. Cancer Res. 54:1994a;2245-2250.
    • (1994) Cancer Res , vol.54 , pp. 2245-2250
    • Christoffersen, J.1    Smeland, E.B.2    Stokke, T.3    Taskén, K.4    Andersson, K.B.5    Blomhoff, H.K.6
  • 13
    • 0013525002 scopus 로고
    • Growth stimulation mediated by G protein coupled receptors in hepatocytes: Synergism with epidermal growth factor and mechanisms of signal transduction
    • G.G. Skouteris. Berlin Heidelberg: Springer Verlag
    • Christoffersen T., Thoresen G.H., Dajani O.F., Sandnes D., Refsnes M. Growth stimulation mediated by G protein coupled receptors in hepatocytes: synergism with epidermal growth factor and mechanisms of signal transduction. Skouteris G.G., Liver Carcinogenesis. 1994b;71-91 Springer Verlag, Berlin Heidelberg.
    • (1994) Liver Carcinogenesis , pp. 71-91
    • Christoffersen, T.1    Thoresen, G.H.2    Dajani, O.F.3    Sandnes, D.4    Refsnes, M.5
  • 14
    • 0027716596 scopus 로고
    • Inhibition by cAMP of Ras-dependent activation of Raf
    • Cook S.J., McCormick F. Inhibition by cAMP of Ras-dependent activation of Raf. Science. 262:1993;1069-1072.
    • (1993) Science , vol.262 , pp. 1069-1072
    • Cook, S.J.1    McCormick, F.2
  • 15
    • 0032559825 scopus 로고    scopus 로고
    • A requirement for cyclin D3-cyclin-dependent kinase (cdk)-4 assembly in the cyclic adenosine monophosphate-dependent proliferation of thyrocytes
    • Depoortere F., Van Keymeulen A., Lukas J., Costagliola S., Bartkova J., Dumont J.E., Bartek J., Roger P.P., Dremier S. A requirement for cyclin D3-cyclin-dependent kinase (cdk)-4 assembly in the cyclic adenosine monophosphate-dependent proliferation of thyrocytes. J Cell Biol. 140:1998;1427-1439.
    • (1998) J Cell Biol , vol.140 , pp. 1427-1439
    • Depoortere, F.1    Van Keymeulen, A.2    Lukas, J.3    Costagliola, S.4    Bartkova, J.5    Dumont, J.E.6    Bartek, J.7    Roger, P.P.8    Dremier, S.9
  • 16
    • 0030857981 scopus 로고    scopus 로고
    • Activation of cyclic AMP-dependent kinase is required but may not be sufficient to mimic cyclic AMP-dependent DNA synthesis and thyroglobulin expression in dog thyroid cells
    • Dremier S., Pohl V., Poteet-Smith C., Roger P.P., Corbin J., Døskeland S.O., Dumont J.E., Maenhaut C. Activation of cyclic AMP-dependent kinase is required but may not be sufficient to mimic cyclic AMP-dependent DNA synthesis and thyroglobulin expression in dog thyroid cells. Mol Cell Biol. 17:1997;6717-6726.
    • (1997) Mol Cell Biol , vol.17 , pp. 6717-6726
    • Dremier, S.1    Pohl, V.2    Poteet-Smith, C.3    Roger, P.P.4    Corbin, J.5    Døskeland, S.O.6    Dumont, J.E.7    Maenhaut, C.8
  • 17
    • 0028176297 scopus 로고
    • CAMP and βγ subunits of heterotrimeric G proteins stimulate the mitogen-activated protein kinase pathway in COS-7 cells
    • Faure M., Voyno-Yasenetskaya T.A., Bourne H.R. cAMP and βγ subunits of heterotrimeric G proteins stimulate the mitogen-activated protein kinase pathway in COS-7 cells. J Biol Chem. 269:1994;7851-7854.
    • (1994) J Biol Chem , vol.269 , pp. 7851-7854
    • Faure, M.1    Voyno-Yasenetskaya, T.A.2    Bourne, H.R.3
  • 18
    • 0019363609 scopus 로고
    • Hormonal regulation of amino acid transport in isolated rat hepatocytes: Properties of a high affinity transport component induced by glucagon and cyclic AMP
    • Fehlmann M., Freychet P. Hormonal regulation of amino acid transport in isolated rat hepatocytes: properties of a high affinity transport component induced by glucagon and cyclic AMP. Adv Cyclic Nucleotide Res. 14:1981;521-527.
    • (1981) Adv Cyclic Nucleotide Res , vol.14 , pp. 521-527
    • Fehlmann, M.1    Freychet, P.2
  • 19
    • 85045533874 scopus 로고    scopus 로고
    • Inhibitory actions of cyclic adenosine monophosphate and pertussis toxin define two distinct epidermal growth factor-regulated pathways leading to activation of mitogen-activated protein kinase in rat hepatocytes
    • Ginès P., Li X., Brown S.E.S., Nakamura T., Guzelian P.S., Heasley L.E., Schrier R.W., Nemenoff R.A. Inhibitory actions of cyclic adenosine monophosphate and pertussis toxin define two distinct epidermal growth factor-regulated pathways leading to activation of mitogen-activated protein kinase in rat hepatocytes. Hepatology. 23:1996;1167-1173.
    • (1996) Hepatology , vol.23 , pp. 1167-1173
    • Ginès, P.1    Li, X.2    Brown, S.E.S.3    Nakamura, T.4    Guzelian, P.S.5    Heasley, L.E.6    Schrier, R.W.7    Nemenoff, R.A.8
  • 20
    • 0028876304 scopus 로고
    • The signal transduction pathway of erythropoietin involves three forms of mitogen-activated protein (MAP) kinase in UT7 erythroleukemia cells
    • Gobert S., Duprez V., Lacombe C., Gisselbrecht S., Mayeux P. The signal transduction pathway of erythropoietin involves three forms of mitogen-activated protein (MAP) kinase in UT7 erythroleukemia cells. Eur J Biochem. 234:1995;75-83.
    • (1995) Eur J Biochem , vol.234 , pp. 75-83
    • Gobert, S.1    Duprez, V.2    Lacombe, C.3    Gisselbrecht, S.4    Mayeux, P.5
  • 21
    • 0025028911 scopus 로고
    • Microtubule-associated-protein (MAP) kinase activated by nerve growth factor and epidermal growth factor in PC12 cells
    • Gotoh Y., Nishida E., Yamashita T., Hoshi M., Kawakami M., Sakai H. Microtubule-associated-protein (MAP) kinase activated by nerve growth factor and epidermal growth factor in PC12 cells. Eur J Biochem. 193:1990;661-669.
    • (1990) Eur J Biochem , vol.193 , pp. 661-669
    • Gotoh, Y.1    Nishida, E.2    Yamashita, T.3    Hoshi, M.4    Kawakami, M.5    Sakai, H.6
  • 22
    • 0029883790 scopus 로고    scopus 로고
    • Insulin, growth factors, and cAMP: Antagonism in the signal transduction pathways
    • Graves L.M., Lawrence J.C. Jr. Insulin, growth factors, and cAMP: antagonism in the signal transduction pathways. Trends Endocrinol Metab. 7:1996;43-50.
    • (1996) Trends Endocrinol Metab , vol.7 , pp. 43-50
    • Graves, L.M.1    Lawrence J.C., Jr.2
  • 23
    • 0029914718 scopus 로고    scopus 로고
    • Epidermal growth factor behaves as a partial agonist in hepatocytes: Effects on DNA synthesis in primary culture and competition with transforming growth factor α
    • Guren T.K., Thoresen G.H., Dajani O.F., Taraldsrud E., Moberg E.R., Christoffersen T. Epidermal growth factor behaves as a partial agonist in hepatocytes: effects on DNA synthesis in primary culture and competition with transforming growth factor α Growth Factors. 13:1996;171-179.
    • (1996) Growth Factors , vol.13 , pp. 171-179
    • Guren, T.K.1    Thoresen, G.H.2    Dajani, O.F.3    Taraldsrud, E.4    Moberg, E.R.5    Christoffersen, T.6
  • 26
    • 0028333768 scopus 로고
    • Sequential protein kinase reactions controlling cell growth and differentiation
    • Johnson G.L., Vaillancourt R.R. Sequential protein kinase reactions controlling cell growth and differentiation. Curr Opin Cell Biol. 6:1994;230-238.
    • (1994) Curr Opin Cell Biol , vol.6 , pp. 230-238
    • Johnson, G.L.1    Vaillancourt, R.R.2
  • 27
    • 0027973043 scopus 로고
    • 1phase arrest mediated by an inhibitor (p27 Kip1) of cyclin-dependent kinase 4 activation
    • 1phase arrest mediated by an inhibitor (p27 Kip1) of cyclin-dependent kinase 4 activation. Cell. 79:1994;487-496.
    • (1994) Cell , vol.79 , pp. 487-496
    • Kato, J.Y.1    Matsuoka, M.2    Polyak, K.3    Massagué, J.4    Sherr, C.J.5
  • 28
    • 0029828566 scopus 로고    scopus 로고
    • Cyclic AMP inhibits activation of mitogen-activated protein kinase and cell proliferation in response to growth factors in cultured rat cortical astrocytes
    • Kurino M., Fukunaga K., Ushio Y., Miyamoto E. Cyclic AMP inhibits activation of mitogen-activated protein kinase and cell proliferation in response to growth factors in cultured rat cortical astrocytes. J Neurochem. 67:1996;2246-2255.
    • (1996) J Neurochem , vol.67 , pp. 2246-2255
    • Kurino, M.1    Fukunaga, K.2    Ushio, Y.3    Miyamoto, E.4
  • 29
    • 0027463240 scopus 로고
    • Phosphorylation of mitogen-activated protein kinases is involved in the epidermal growth factor and phorbol ester, but not in the thyrotropin/cAMP, thyroid mitogenic pathway
    • Lamy F., Wilkin F., Baptist M., Posada J., Roger P.P., Dumont J.E. Phosphorylation of mitogen-activated protein kinases is involved in the epidermal growth factor and phorbol ester, but not in the thyrotropin/cAMP, thyroid mitogenic pathway. J Biol Chem. 268:1993;8398-8401.
    • (1993) J Biol Chem , vol.268 , pp. 8398-8401
    • Lamy, F.1    Wilkin, F.2    Baptist, M.3    Posada, J.4    Roger, P.P.5    Dumont, J.E.6
  • 31
    • 0029976573 scopus 로고    scopus 로고
    • CAMP-mediated growth inhibition in fibroblasts is not mediated via mitogen-activated protein (MAP) kinase (ERK) inhibition: CAMP-dependent protein kinase induces a temporal shift in growth factor-stimulated MAP kinases
    • McKenzie F.R., Pouysségur J. cAMP-mediated growth inhibition in fibroblasts is not mediated via mitogen-activated protein (MAP) kinase (ERK) inhibition: cAMP-dependent protein kinase induces a temporal shift in growth factor-stimulated MAP kinases. J Biol Chem. 271:1996;13476-13483.
    • (1996) J Biol Chem , vol.271 , pp. 13476-13483
    • McKenzie, F.R.1    Pouysségur, J.2
  • 32
  • 33
    • 0031971122 scopus 로고    scopus 로고
    • 2αin hepatocytes is sustained, and like the effect of epidermal growth factor, mediated through pertussis toxin-sensitive mechanisms
    • 2αin hepatocytes is sustained, and like the effect of epidermal growth factor, mediated through pertussis toxin-sensitive mechanisms. J Cell Physiol. 175:1998;348-358.
    • (1998) J Cell Physiol , vol.175 , pp. 348-358
    • Melien, Ø.1    Thoresen, G.H.2    Sandnes, D.3    Østby, E.4    Christoffersen, T.5
  • 34
    • 0027301858 scopus 로고
    • 1phase in the proliferating primary rat hepatocytes, but inhibits their entries into S phase and RB's phosphorylation
    • 1phase in the proliferating primary rat hepatocytes, but inhibits their entries into S phase and RB's phosphorylation. Biochem Biophys Res Commun. 195:1993;84-89.
    • (1993) Biochem Biophys Res Commun , vol.195 , pp. 84-89
    • Okamoto, Y.1    Kikuchi, E.2    Matsumoto, M.3    Nakano, H.4
  • 35
    • 0024473604 scopus 로고
    • 1events and regulation of cell proliferation
    • 1events and regulation of cell proliferation. Science. 246:1989;603-608.
    • (1989) Science , vol.246 , pp. 603-608
    • Pardee, A.B.1
  • 36
    • 0027721992 scopus 로고
    • Epidermal growth factor and insulin stimulate MAP kinase activity in cultured hepatocytes
    • Peak M., Yeaman S.J., Agius L. Epidermal growth factor and insulin stimulate MAP kinase activity in cultured hepatocytes. Biochem Soc Trans. 21:1993;494S.
    • (1993) Biochem Soc Trans , vol.21
    • Peak, M.1    Yeaman, S.J.2    Agius, L.3
  • 39
    • 0342626828 scopus 로고
    • Hormonal stimulation of DNA synthesis in primary cultures of adult rat hepatocytes
    • Richman R.A., Claus T.H., Pilkis S.J., Friedman D.L. Hormonal stimulation of DNA synthesis in primary cultures of adult rat hepatocytes. Proc Natl Acad Sci U S A. 73:1976;3589-3593.
    • (1976) Proc Natl Acad Sci U S A , vol.73 , pp. 3589-3593
    • Richman, R.A.1    Claus, T.H.2    Pilkis, S.J.3    Friedman, D.L.4
  • 40
    • 0029187438 scopus 로고
    • Multiple facets of the modulation of growth by cAMP
    • Roger P.P., Reuse S., Maenhaut C., Dumont J.E. Multiple facets of the modulation of growth by cAMP. Vitam Horm. 51:1995;59-191.
    • (1995) Vitam Horm , vol.51 , pp. 59-191
    • Roger, P.P.1    Reuse, S.2    Maenhaut, C.3    Dumont, J.E.4
  • 41
    • 0030925608 scopus 로고    scopus 로고
    • Activation of mitogen-activated protein kinase in freshly isolated rat hepatocytes by both a calcium- and a protein kinase C-dependent pathway
    • Romanelli A., Van De Werve G. Activation of mitogen-activated protein kinase in freshly isolated rat hepatocytes by both a calcium- and a protein kinase C-dependent pathway. Metabolism. 46:1997;548-555.
    • (1997) Metabolism , vol.46 , pp. 548-555
    • Romanelli, A.1    Van De Werve, G.2
  • 42
    • 0029011218 scopus 로고
    • The MAPK signaling cascade
    • Seger R., Krebs E.G. The MAPK signaling cascade. FASEB J. 9:1995;726-735.
    • (1995) FASEB J , vol.9 , pp. 726-735
    • Seger, R.1    Krebs, E.G.2
  • 43
    • 0017101039 scopus 로고
    • Preparation of isolated rat liver cells
    • Seglen P.O. Preparation of isolated rat liver cells. Methods Cell Biol. 13:1976;29-83.
    • (1976) Methods Cell Biol , vol.13 , pp. 29-83
    • Seglen, P.O.1
  • 45
    • 0031022710 scopus 로고    scopus 로고
    • Activation of mitogen-activated protein kinase by norepinephrine in brown adipocytes from rats
    • Shimizu Y., Tanishita T., Minokoshi Y., Shimazu T. Activation of mitogen-activated protein kinase by norepinephrine in brown adipocytes from rats. Endocrinology. 138:1997;248-253.
    • (1997) Endocrinology , vol.138 , pp. 248-253
    • Shimizu, Y.1    Tanishita, T.2    Minokoshi, Y.3    Shimazu, T.4
  • 46
    • 0028824346 scopus 로고
    • Forskolin inhibits protein kinase C-induced mitogen-activated protein kinase activity in MC3T3-E1 osteoblasts
    • Siddhanti S.R., Hartle JE, II, Quarles L.D. Forskolin inhibits protein kinase C-induced mitogen-activated protein kinase activity in MC3T3-E1 osteoblasts. Endocrinology. 136:1995;4834-4841.
    • (1995) Endocrinology , vol.136 , pp. 4834-4841
    • Siddhanti, S.R.1    Hartle J.E. II2    Quarles, L.D.3
  • 47
    • 0030989153 scopus 로고    scopus 로고
    • Differential regulation of the mitogen-activated protein and stress-activated protein kinase cascades by adrenergic agonists in quiescent and regenerating adult rat hepatocytes
    • Spector M.S., Auer K.L., Jarvis W.D., Ishac E.J.N., Gao B., Kunos G., Dent P. Differential regulation of the mitogen-activated protein and stress-activated protein kinase cascades by adrenergic agonists in quiescent and regenerating adult rat hepatocytes. Mol Cell Biol. 17:1997;3556-3565.
    • (1997) Mol Cell Biol , vol.17 , pp. 3556-3565
    • Spector, M.S.1    Auer, K.L.2    Jarvis, W.D.3    Ishac, E.J.N.4    Gao, B.5    Kunos, G.6    Dent, P.7
  • 48
    • 0028087992 scopus 로고
    • Comparative effects of hepatocyte growth factor and epidermal growth factor on motility, morphology, mitogenesis, and signal transduction of primary rat hepatocytes
    • Stolz D.B., Michalopoulos G.K. Comparative effects of hepatocyte growth factor and epidermal growth factor on motility, morphology, mitogenesis, and signal transduction of primary rat hepatocytes. J Cell Biochem. 55:1994;445-464.
    • (1994) J Cell Biochem , vol.55 , pp. 445-464
    • Stolz, D.B.1    Michalopoulos, G.K.2
  • 51
    • 0031937366 scopus 로고    scopus 로고
    • Response to transforming growth factor α (TGFα) and epidermal growth factor (EGF) in hepatocytes: Lower EGF receptor affinity of TGFα is associated with more sustained activation of p42/p44 mitogen-activated protein kinase and greater efficacy in stimulation of DNA synthesis
    • Thoresen G.H., Guren T.K., Sandnes D., Peak M., Agius L., Christoffersen T. Response to transforming growth factor α (TGFα) and epidermal growth factor (EGF) in hepatocytes: lower EGF receptor affinity of TGFα is associated with more sustained activation of p42/p44 mitogen-activated protein kinase and greater efficacy in stimulation of DNA synthesis. J Cell Physiol. 175:1998;10-18.
    • (1998) J Cell Physiol , vol.175 , pp. 10-18
    • Thoresen, G.H.1    Guren, T.K.2    Sandnes, D.3    Peak, M.4    Agius, L.5    Christoffersen, T.6
  • 52
    • 0028111836 scopus 로고
    • B-Raf-dependent regulation of the MEK-1/mitogen-activated protein kinase pathway in PC12 cells and regulation by cyclic AMP
    • Vaillancourt R.R., Gardner A.M., Johnson G.L. B-Raf-dependent regulation of the MEK-1/mitogen-activated protein kinase pathway in PC12 cells and regulation by cyclic AMP. Mol Cell Biol. 14:1994;6522-6530.
    • (1994) Mol Cell Biol , vol.14 , pp. 6522-6530
    • Vaillancourt, R.R.1    Gardner, A.M.2    Johnson, G.L.3
  • 53
    • 0024426547 scopus 로고
    • 3H]-thymidine labelling patterns to determine rapid changes in the rate of onset of DNA replication
    • 3H]-thymidine labelling patterns to determine rapid changes in the rate of onset of DNA replication. J Cell Physiol. 141:1989;371-382.
    • (1989) J Cell Physiol , vol.141 , pp. 371-382
    • Vintermyr, O.K.1    Mellgren, G.2    Bøe, R.3    Døskeland, S.O.4
  • 54
    • 0030963439 scopus 로고    scopus 로고
    • CAMP activates MAP kinase and Elk-1 through a B-Raf- and Rap1-dependent pathway
    • Vossler M.R., Yao H., York R.D., Pan M-G, Rim C.S., Stork P.J.S. cAMP activates MAP kinase and Elk-1 through a B-Raf- and Rap1-dependent pathway. Cell. 89:1997;73-82.
    • (1997) Cell , vol.89 , pp. 73-82
    • Vossler, M.R.1    Yao, H.2    York, R.D.3    Pan, M.-G.4    Rim, C.S.5    Stork, P.J.S.6
  • 57
    • 0030994196 scopus 로고    scopus 로고
    • Signalling pathways involved in the mitogenic effects of cAMP
    • Withers D.J. Signalling pathways involved in the mitogenic effects of cAMP. Clin Sci. 92:1997;445-451.
    • (1997) Clin Sci , vol.92 , pp. 445-451
    • Withers, D.J.1
  • 58
    • 0027772672 scopus 로고
    • Inhibition of the EGF-activated MAP kinase signaling pathway by adenosine 3′,5′-monophosphate
    • Wu J., Dent P., Jelinek T., Wolfman A., Weber M.J., Sturgill T.W. Inhibition of the EGF-activated MAP kinase signaling pathway by adenosine 3′,5′-monophosphate. Science. 262:1993;1065-1069.
    • (1993) Science , vol.262 , pp. 1065-1069
    • Wu, J.1    Dent, P.2    Jelinek, T.3    Wolfman, A.4    Weber, M.J.5    Sturgill, T.W.6
  • 59
    • 0030601228 scopus 로고    scopus 로고
    • Cyclic AMP stimulates the phosphorylation and activation of p42 and p44 mitogen-activated protein kinases in 3T3-F442A preadipocytes
    • Yarwood S.J., Kilgour E., Anderson N.G. Cyclic AMP stimulates the phosphorylation and activation of p42 and p44 mitogen-activated protein kinases in 3T3-F442A preadipocytes. Biochem Biophys Res Commun. 224:1996;734-739.
    • (1996) Biochem Biophys Res Commun , vol.224 , pp. 734-739
    • Yarwood, S.J.1    Kilgour, E.2    Anderson, N.G.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.