A tyrosinase peptide presented by HLA-B35 is recognized on a human melanoma by autologous cytotoxic T lymphocytes

International Journal of Cancer

Volumn 83, Issue 6, 1999, Pages 755-759

  Morel, Sandra ^a   Ooms, Annie ^b   Van Pel, Aline ^a   Wölfel, Thomas ^c   Brichard, Vincent G ^d   Van Der Bruggen, Pierre ^a   Van Den Eynde, Benoît J ^a,e   Degiovanni, Gérard ^b  

^a UNIVERSITÉ CATHOLIQUE DE LOUVAIN   (Belgium)

^b UNIVERSITY OF LIÈGE   (Belgium)

^c UNIVERSITY MEDICAL CENTER MAINZ   (Germany)

^d INSTITUT CURIE   (France)

^e LUDWIG INSTITUTE FOR CANCER RESEARCH   (Belgium)

Author keywords

[No Author keywords available]

Indexed keywords

HLA B ANTIGEN; MONOPHENOL MONOOXYGENASE;

ALLELE; AMINO ACID SEQUENCE; ANTIGEN PRESENTATION; ANTIGEN RECOGNITION; ARTICLE; CYTOTOXIC T LYMPHOCYTE; HUMAN; HUMAN CELL; IMMUNOTHERAPY; LYMPHOCYTE CLONE; MELANOMA; PRIORITY JOURNAL; T LYMPHOCYTE ACTIVATION;

ALLELES; AMINO ACID SEQUENCE; ANIMALS; B-LYMPHOCYTES; CELL LINE, TRANSFORMED; COS CELLS; CYTOTOXICITY, IMMUNOLOGIC; HERPESVIRUS 4, HUMAN; HLA-B35 ANTIGEN; HUMANS; MELANOMA; MONOPHENOL MONOOXYGENASE; PEPTIDE FRAGMENTS; RECOMBINANT PROTEINS; T-LYMPHOCYTES, CYTOTOXIC; TRANSFECTION; TUMOR CELLS, CULTURED;

EID: 0032710052     PISSN: 00207136     EISSN: None     Source Type: Journal    
DOI: 10.1002/(SICI)1097-0215(19991210)83:6<755::AID-IJC10>3.0.CO;2-S     Document Type: Article

References (23)

1. ALTMAN, J.D., MOSS, P.A.H., GOULDER, P.J.R., BAROUCH, D.H., MCHEYZER-WILLIAMS, M.G., BELL, J.I., MCMICHAEL, A.J. and DAVIS, M.M., Phenotypic analysis of antigen-specific T lymphocytes. Science, 274, 94-96 (1996).
2. BRICHARD, V., VAN PEL, A., WÖLFEL, T., WÖLFEL, C., DE PLAEN, E., LETHÉ, B., COULJE, P. and BOON, T., The tyrosinase gene codes for an antigen recognized by autologous cytolytic T lymphocytes on HLA-A2 melanomas, J. exp. Med., 178, 489-495 (1993).
3. BRICHARD, V.G., HERMAN, J., VAN PEL, A., WILDMANN, C., GAUGLER, B., WÖLFEL, T., BOON, T. and LETHÉ, B., A tyrosinase nonapeptide presented by HLA-B44 is recognized on a human melanoma by autologous cytolytic T lymphocytes. Europ. J. Immunol., 26, 224-230 (1996).
4. DEGIOVASNI, G., LAHAYE, T., HÉRIN, M., HAINAUT, P. and BOON, T., Antigenic heterogeneity of a human melanoma tumor detected by autologous CTL clones. Europ. J. Immunol., 18, 671-676 (1988).
5. + T lymphocytes producing tumor necrosis factor alpha spots in response to peptide antigens. J. immunol. Methods, 203, 141-152 (1997).
6. JÄGER, E., RINGHOFFER, M., DIENES, H.P., ARAND, M., KARBACH, J., JÄGER, D., ILSEMANN, C., HAGEDORN, M., OESCH, F. and KNUTH, A., Granulocytemacrophage-colony-stimulating factor enhances immune responses to melanoma-associated peptides in vivo. Int. J. Cancer, 67, 54-62 (1996).
7. KAWAKAMI, Y., ROBBINS, P.F., WANG, X., TUPESIS, J.P., PARKHURST, M.R., KANG, X., SAKAGUCHI, K., APPELLA, E. and ROSENBERG, S.A., Identification of new melanoma epitopes on melanosomal proteins recognized by tumor infiltrating T lymphocytes restricted by HLA-A1, -A2, and -A3 alleles. J. Immunol., 161, 6985-6992 (1998).
8. KITTLESEN, D.J., THOMPSON, L.W., GULDEN, P.H., SKIPPER, J.C.A., COLELLA, T.A., SHABANOWITZ, J.A., HUNT, D.F., ENGELHARD, V.H. and SLINGLUFF, C.L., Human melanoma patients recognize an HLA-A1-restricted CTL epitope from tyrosinase containing two cysteine residues: implications for tumor vaccine development. J. Immunol., 160, 2099-2106 (1998).
9. + T cells from peripheral blood of a melanoma patient recognize peptides derived from nomnutated tyrosinase. Cancer Res., 58, 296-301 (1998).
10. KOBAYASHI, H., KOKUBO, T., TAKAHASHI, M., SATO, K., MIYOKAWA, N., KIMURA, S., KINOUCHI, R. and KATAGIRI, M., Tyrosinase epitope recognized by an HLA-DR-restricted T-cell line from a Vogt-Koyanagi-Harada disease patient. Immunogenetics, 47, 398-403 (1998).
11. LETHÉ, B., LUCAS, S., MICHAUX, L., DE SMET, C. GODELAINE, D., SERRANO, A., DE PLAEN, E. and BOON, T., LAGE-I, a new gene with tumor specificity. Int. J. Cancer, 76, 903-908 (1998).
12. MANDRUZZATO, S., BRASSEUR, F., ANDRY, G., BOON, T. and VAN DER BRUGGEN, P., A CASP-8 mutation recognized by cytolytic T lymphocytes on a human head and neck carcinoma. J. exp. Med. 186, 785-793 (1997).
13. MARCHAND, M. and 24 others, Tumor regressions observed in patients with metastatic melanoma treated with an antigenic peptide encoded by gene MAGE-3 and presented by HLA-A1. Int. J. Cancer, 80, 219-230 (1999).
14. MORI, M., BEATTY, P.G., GRAVES, M., BOUCHER, K.M. and MILFORD, E.L., HLA gene and haplotype frequencies in the North American population. Transplantation, 64, 1017-1027 (1997).
15. NESTLE, F.O., ALIJAGIC, S., GILLIET, M., SUN, Y., GRABBE, S., DUMMER, R., BURG, G. and SCHADENDORF, D., Vaccination of melanoma patients with peptide- or tumor lysate-pulsed dendritic cells. Nature (Med.), 4, 328-332 (1998).
16. OGG, G.S., DUNBAR, P.R., RROMERO, P., CHEN, J.-L. and CERUNDOLO, V., High frequency of skin-homing melanocyte-specific cytotoxic T lymphocytes in autoimmune vitiligo. J. exp. Med., 188,1203-1208 (1998).
17. RICHARDS, J.M., MEHTA, N., RAMMING, K. and SKOSEY, P., Sequential chemoimmunotherapy in the treatment of metastatic melanoma. J. clin. Oncol. 10, 1338-1343 (1992).
18. ROSENBERG, S.A. and 15 others, Immunologic and therapeutic evaluation of a synthetic peptide vaccine for the treatment of patients with metastatic melanoma. Nature (Med.). 4, 321-327 (1998).
19. STEINLE, A., FALK, K., RÖTZSCHKE, O., GNAU, V., STEVANOVIC, S., JUNG, G., SCHENDEL, D.J. and RAMMENSEE, H.-G., Motif of HLA-B*3503 peptide ligands. Immunogenetics, 43, 105-107 (1995).
20. TOES, R.E.M., OSSENDORP, F., OFFRINGA, R. and MELIEF, C.J.M., CD4 T cells and their role in antitumor immune responses. J. exp. Med., 189, 753-756 (1999).
21. VAN DEN EYNDE, B. and VAN DER BRUGGEN, P., T cell-defined tumor antigens. Curr. Opin. Immunol., 9, 684-693 (1997).
22. VISSEREN, M.J., VAN DER BURG, S.H., HAWES, G.E., VAN DER VOORT, E.I., VAN DEN ELSEN, P.J. and MELIEF, C.J., Affinity, specificity and T-cell-receptor diversity of melanoma-specific CTL generated in vitro against a single tyrosinase epitope. Int. J. Cancer, 72, 1122-1128 (1997).
23. WÖLFEL, T., VAN PEL, A., BRICHARD, V., SCHNEIDER, J., SELIGER, B., MEYER ZUM BÜSCHENFELDE, K.-H. and BOON, T., Two tyrosinase nonapeptides recognized on HLA-A2 melanomas by autologous cytolytic T lymphocytes. Europ. J. Immunol., 24, 759-764 (1994).