Phage display of a cellulose binding domain from Clostridium thermocellum and its application as a tool for antibody engineering

Journal of Immunological Methods

Volumn 228, Issue 1-2, 1999, Pages 151-162

  Berdichevsky, Yevgeny ^a   Ben Zeev, Efrat ^a   Lamed, Raphael ^a   Benhar, Itai ^a  

^a TEL AVIV UNIVERSITY   (Israel)

Author keywords

Antibody engineering; Cellulose binding domain; Phage display; Single chain Fv

Indexed keywords

BINDING PROTEIN; CELLULOSE; HYBRID PROTEIN; IMMUNOGLOBULIN FRAGMENT;

ARTICLE; CLOSTRIDIUM THERMOCELLUM; ENZYME LINKED IMMUNOSORBENT ASSAY; GENETIC ENGINEERING; NONHUMAN; PHAGE DISPLAY; PRIORITY JOURNAL;

ANIMALS; ANTIBODIES; BACTERIAL PROTEINS; BASE SEQUENCE; BINDING SITES; CELLULOSE; CLONING, MOLECULAR; CLOSTRIDIUM; DNA PRIMERS; ESCHERICHIA COLI; IMMUNOGLOBULIN FRAGMENTS; PEPTIDE LIBRARY; PROTEIN ENGINEERING; RECOMBINANT FUSION PROTEINS;

EID: 0032703297     PISSN: 00221759     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0022-1759(99)00096-4     Document Type: Article

References (34)

1. Barbas C.F. III, Kang A.S., Lerner R.A., Benkovic S.J. Assembly of combinatorial antibody libraries on phage surfaces: the gene III site. Proc. Natl. Acad. Sci. U.S.A. 88:1991;7978-7982.
2. Bayer E.A., Morag E., Lamed R. The cellulosome - a treasure-trove for biotechnology. Trends Biotechnol. 12:1995;379-386.
3. Bedzyk W.D., Weidner K.M., Denzin L.K., Johnson L.S., Hardman K.D., Pantoliano M.W., Asel E.D., Voss E.W. Jr. Immunological and structural characterization of a high affinity anti-fluorescein single-chain antibody. J. Biol. Chem. 265:1990;18615-18620.
4. Bonnycastle L.L.C., Brown K., Tang J., Scott J.K. Assaying phage-borne peptides by phage capture on fibrinogen or streptavidin. Biol. Chem. 378:1997;509-515.
5. Brinkmann U., Chowdhury P.S., Roscoe D.M., Pastan I. Phage display of disulfide-stabilized Fv fragments. J. Immunol. Methods. 182:1995;41-50.
6. Carroll W.L., Mendel E., Levi S. Hybridoma fusion cell lines contain an aberrant kappa transcript. Mol. Immunol. 25:1988;991-995.
7. Chowdhury P.S., Viner J.L., Beers R., Pastan I. Isolation of a high-affinity stable single-chain Fv specific for mesothelin from DNA-immunized mice by phage display and construction of a recombinant immunotoxin with anti-tumor activity. Proc. Natl. Acad. Sci. U.S.A. 95:1998;669-674.
8. Courtney B.C., Williams K.C., Schlager J.J. A phage display vector with improved stability, applicability and ease of manipulation. Gene. 165:1995;139-140.
9. de Haard H., Henderikx P., Hoogenboom H.R. Creating and engineering human antibodies for immunotherapy. Adv. Drug Delivery Rev. 31:1998;5-31.
10. Duan L., Pomeranz R.J. Elimination of endogenous aberrant kappa chain transcripts from sp2/0-derived hybridoma cells by specific ribozyme cleavage: utility in genetic therapy of HIV-1 infections. Nucleic Acids Res. 22:1994;5433-5438.
11. Dziegiel M., Nielsen L.K., Andersen P.S., Blancher A., Dickmeiss E., Engberg J. Phage display used for gene cloning of human recombinant antibody against the erythrocyte surface antigen, rhesus D. J. Immunol. Methods. 182:1995;7-19.
12. Holliger P., Prospero T., Winter G. "Diabodies": small bivalent and bispecific antibody fragments. Proc. Natl. Acad. Sci. U.S.A. 90:1993;6444-6448.
13. Hoogenboom H.R., Griffiths A.D., Johnson K.S., Chiswell D.J., Hudson P., Winter G. Multi-subunit proteins on the surface of filamentous phage: methodologies for displaying antibody (Fab) heavy and light chains. Nucleic Acids Res. 19:1991;4133-4137.
14. Hoogenboom H.R., de Bruine A.P., Hufton S.E., Hoet R.M., Arends J.W., Roovers R.C. Antibody phage display technology and its applications. Immunotechnology. 4:1998;1-20.
15. Köhler G., Milstein C. Continuous cultures of fused cells secreting antibody of predefined specificity. Nature. 256:1975;495-497.
16. Krebber A., Bornhauser S., Burmester J., Honegger A., Willuda J., Bosshard H.R., Plückthun A. Reliable cloning of functional antibody variable domains from hybridomas and spleen cell repertoires employing a reengineered phage display system. J. Immunol. Methods. 201:1997;35-55.
17. Larrick J.W., Danielsson L., Brenner A.C., Abrahamsson M., Fry K., Borrebaek C.A.K. Rapid cloning of rearranged immunoglobulin genes from human hybridoma cells using mixed primers and polymerase chain reaction. Biochem. Biophys. Res. Commun. 160:1989;1250-1256.
18. Le K.D., Gilkes N.R., Kilburn D.G., Miller R.C.J., Saddler J.N., Warren R.A.J. A streptavidin-cellulose binding domain fusion protein that binds biotinylated proteins to cellulose. Enzyme Microb. Technol. 16:1994;496-500.
19. Lowman H.B. Bacteriophage display and discovery of peptide leads for drug development. Annu. Rev. Biophys. Biomol. Struct. 26:1997;401-424.
20. Marks J.D., Tristrem M., Karpas A., Winter G. Oligonucleotide primers for polymerase chain reaction amplification of human immunoglobulin variable genes and design of family-specific oligonucleotide probes. Eur. J. Immunol. 21:1991;985-991.
21. McCafferty J., Griffith A.D., Winter G., Chiswell D.J. Phage antibodies: filamentous phage displaying antibody variable domains. Nature. 348:1990;552-554.
22. McGuinness B.T., Walter G., FitzGerald K., Schuler P., Mahoney W., Duncan A.R., Hoogenboom H.R. Phage diabody repertoires for selection of large numbers of bispecific antibody fragments. Nat. Biotechnol. 14:1996;1149-1154.
23. Morag E., Lapidot A., Govorko D., Lamed R., Wilchek M., Bayer E.A., Shoham Y. Expression, purification, and characterization of the cellulose-binding domain of the scaffolding subunit from the cellulosome of Clostridium thermocellum. Appl. Environ. Microbiol. 61:1995;1980-1986.
24. Ong E., Greenwood J.M., Gilkes N.R., Kilburn D.G., Miller R.C.J., Warren R.A.J. The cellulose-binding domains of cellulases: tools for biotechnology. Trends Biotechnol. 7:1989;239-243.
25. Orlandi R., Gussow D.H., Jones P.T., Winter G. Cloning immunoglobulin variable domains for expression by the polymerase chain reaction. Proc. Natl. Acad. Sci. U.S.A. 86:1989;3833-3837.
26. Rader C. III, Barbas C.F. Phage display of combinatorial antibody libraries. Curr. Opin. Biotechnol. 8:1997;503-508.
27. Riechmann L., Holliger P. The C-terminal domain of TolA is the coreceptor for filamentous phage infection of E. coli. Cell. 90:1998;351-360.
28. Sambrook, J.L., Fritsch, E.F., Maniatis, T., 1989. Molecular Cloning: A Laboratory Manual, 2nd edn. Cold Spring Harbor Laboratory Press, Cold Spring Harbor, NY.
29. Seehaus T., Breitling F., Dübel S., Klewinghuas I., Little M. A vector for removal of deletion mutants from antibody libraries. Gene. 114:1992;235-237.
30. Skerra A., Pfitzinger I., Plückthun A. The functional expression of antibody Fv fragments in Escherichia coli: improved vectors and a generally applicable purification technique. Biotechnology (NY). 9:1991;273-278.
31. Smith G.P., Patel S.U., Windass J.D., Thornton J.M., Winter G., Griffiths A.D. Small binding proteins selected from a combinatorial repertoire of knottins displayed on phage. J. Mol. Biol. 277:1998;317-332.
32. Stempfer G., Holl-Neugebauer B., Rudolph R. Improved refolding of an immobilized fusion protein. Nat. Biotechnol. 14:1996;329-334.
33. Tormo J., Lamed R., Chirino A.J., Morag E., Bayer E.A., Shoham Y., Steitz T.A. Crystal structure of a bacterial family: III. Cellulose-binding domain: a general mechanism for attachment to cellulose. EMBO J. 15:1996;5739-5751.
34. Winter G., Griffiths A.D., Hawkins R.E., Hoogenboom H.R. Making antibody by phage display technology. Ann. Rev. Immunol. 12:1994;433-455.