메뉴 건너뛰기




Volumn 46, Issue C, 1999, Pages 297-324

Mechanisms of Antithrombotic Drugs

Author keywords

[No Author keywords available]

Indexed keywords

ANTITHROMBOCYTIC AGENT; DRUG DERIVATIVE; FIBRINOGEN RECEPTOR; FIBRINOLYTIC AGENT; HEPARIN; HIRUDIN DERIVATIVE; HIRULOG; LOW MOLECULAR WEIGHT HEPARIN; PEPTIDE FRAGMENT; PURINE P2 RECEPTOR; RECOMBINANT PROTEIN; VITAMIN K GROUP;

EID: 0032619358     PISSN: 10543589     EISSN: None     Source Type: Book Series    
DOI: 10.1016/S1054-3589(08)60474-3     Document Type: Chapter
Times cited : (12)

References (129)
  • 1
    • 0030952162 scopus 로고    scopus 로고
    • Recombinant hirudin in the prevention of venous thromboembolism in patients undergoing elective hip surgery
    • Agnelli G., and Sonaglia F. Recombinant hirudin in the prevention of venous thromboembolism in patients undergoing elective hip surgery. Semin. Thromb. Hemost. 23 (1997) 143-148
    • (1997) Semin. Thromb. Hemost. , vol.23 , pp. 143-148
    • Agnelli, G.1    Sonaglia, F.2
  • 2
    • 0029908645 scopus 로고    scopus 로고
    • Platelet activation via trimeric GTP-binding proteins
    • Akkerman J.W., and van Willigen G. Platelet activation via trimeric GTP-binding proteins. Haemostasis 26 (1996) 199-209
    • (1996) Haemostasis , vol.26 , pp. 199-209
    • Akkerman, J.W.1    van Willigen, G.2
  • 3
    • 0016694726 scopus 로고
    • The early history of vitamin K
    • Almquist H.J. The early history of vitamin K. Am. J. Clin. Nutr. 28 (1975) 656-659
    • (1975) Am. J. Clin. Nutr. , vol.28 , pp. 656-659
    • Almquist, H.J.1
  • 4
    • 0031409977 scopus 로고    scopus 로고
    • Recognition and management of heparin-induced thrombocytopenia (HIT) and thrombosis
    • Alving B.M., and Krishnamurti C. Recognition and management of heparin-induced thrombocytopenia (HIT) and thrombosis. Semin. Thromb. Hemost. 23 (1997) 569-574
    • (1997) Semin. Thromb. Hemost. , vol.23 , pp. 569-574
    • Alving, B.M.1    Krishnamurti, C.2
  • 6
    • 0025485759 scopus 로고
    • Heparin, the miracle drug: A brief history of its discovery
    • Ancalmo N., and Ochsner J. Heparin, the miracle drug: A brief history of its discovery. J. La. State Med. Soc. 142 (1990) 22-24
    • (1990) J. La. State Med. Soc. , vol.142 , pp. 22-24
    • Ancalmo, N.1    Ochsner, J.2
  • 7
    • 0032522549 scopus 로고    scopus 로고
    • Heparin is more effective than inogatran, a low-molecular weight thrombin inhibitor in suppressing ischemia and recurrent angina in unstable coronary disease: Thrombin Inhibition in Myocardial Ischemia (TRIM) Study Group
    • Andersen K., and Dellborg M. Heparin is more effective than inogatran, a low-molecular weight thrombin inhibitor in suppressing ischemia and recurrent angina in unstable coronary disease: Thrombin Inhibition in Myocardial Ischemia (TRIM) Study Group. Am. J. Cardiol. 81 (1998) 939-944
    • (1998) Am. J. Cardiol. , vol.81 , pp. 939-944
    • Andersen, K.1    Dellborg, M.2
  • 9
    • 0028120906 scopus 로고
    • Collaborative overview of randomised trials of antiplatelet therapy. I. Prevention of death, myocardial infarction and stroke by prolonged antiplatelet therapy in various categories of patients: Antiplatelet Trialists' Collaboration
    • Anonymous. Collaborative overview of randomised trials of antiplatelet therapy. I. Prevention of death, myocardial infarction and stroke by prolonged antiplatelet therapy in various categories of patients: Antiplatelet Trialists' Collaboration. Brit Med J. 308 (1994) 81-106
    • (1994) Brit Med J. , vol.308 , pp. 81-106
  • 10
    • 0028128106 scopus 로고
    • Collaborative overview of randomised trials of antiplatelet therapy. II. Maintenance of vascular graft or arterial patency by antiplatelet therapy: Antiplatelet Trialists' Collaboration
    • Anonymous. Collaborative overview of randomised trials of antiplatelet therapy. II. Maintenance of vascular graft or arterial patency by antiplatelet therapy: Antiplatelet Trialists' Collaboration. Brit Med J. 308 (1994) 159-168
    • (1994) Brit Med J. , vol.308 , pp. 159-168
  • 11
    • 0028217263 scopus 로고
    • Collaborative overview of randomised trials of antiplatelet therapy. III. Reduction in venous thrombosis and pulmonary embolism by antiplatelet prophylaxis among surgical and medical patients: Antiplatelet Trialists' Collaboration
    • Anonymous. Collaborative overview of randomised trials of antiplatelet therapy. III. Reduction in venous thrombosis and pulmonary embolism by antiplatelet prophylaxis among surgical and medical patients: Antiplatelet Trialists' Collaboration. Brit Med J. 308 (1994) 235-246
    • (1994) Brit Med J. , vol.308 , pp. 235-246
  • 12
    • 0028092111 scopus 로고
    • Hirudin in acute myocardial infarction: Safety report from the Thrombolysis and Thrombin Inhibition in Myocardial Infarction (TIMI) 9A Trial
    • Antman E.M. Hirudin in acute myocardial infarction: Safety report from the Thrombolysis and Thrombin Inhibition in Myocardial Infarction (TIMI) 9A Trial. Circulation 90 (1994) 1624-1630
    • (1994) Circulation , vol.90 , pp. 1624-1630
    • Antman, E.M.1
  • 13
    • 0032575328 scopus 로고    scopus 로고
    • Low-molecular-weight heparins: An intriguing new twist with profound implications
    • Antman E.M., and Handin R. Low-molecular-weight heparins: An intriguing new twist with profound implications. Circulation 98 (1998) 287-289
    • (1998) Circulation , vol.98 , pp. 287-289
    • Antman, E.M.1    Handin, R.2
  • 14
    • 0030460491 scopus 로고    scopus 로고
    • Platelet prostanoid receptors
    • Armstrong R.A. Platelet prostanoid receptors. Pharmacol. Ther. 72 (1996) 171-191
    • (1996) Pharmacol. Ther. , vol.72 , pp. 171-191
    • Armstrong, R.A.1
  • 15
    • 0025298914 scopus 로고
    • Novel mechanism of heterologous desensitization of adenylate cyclase: Prostaglandins bind with different affinities to both stimulatory and inhibitory receptors on platelets
    • Ashby B. Novel mechanism of heterologous desensitization of adenylate cyclase: Prostaglandins bind with different affinities to both stimulatory and inhibitory receptors on platelets. Mol. Pharmacol. 38 (1990) 46-53
    • (1990) Mol. Pharmacol. , vol.38 , pp. 46-53
    • Ashby, B.1
  • 16
    • 0031417958 scopus 로고    scopus 로고
    • Clinical trial results with hirudin and bivalirudin for acute coronary artery syndromes
    • Bates E.R. Clinical trial results with hirudin and bivalirudin for acute coronary artery syndromes. Semin. Thromb. Hemost. 23 (1997) 575-581
    • (1997) Semin. Thromb. Hemost. , vol.23 , pp. 575-581
    • Bates, E.R.1
  • 17
    • 0031439715 scopus 로고    scopus 로고
    • Molecular basis for the resistance of fibrin-bound thrombin to inactivation by heparin/serpin complexes
    • Becker D.L., Fredenburgh J.C., Stafford A.R., and Weitz J.I. Molecular basis for the resistance of fibrin-bound thrombin to inactivation by heparin/serpin complexes. Adv. Exp. Med. Biol. 425 (1997) 55-66
    • (1997) Adv. Exp. Med. Biol. , vol.425 , pp. 55-66
    • Becker, D.L.1    Fredenburgh, J.C.2    Stafford, A.R.3    Weitz, J.I.4
  • 18
    • 0029782578 scopus 로고    scopus 로고
    • Clinical trials of Hirulog in patients undergoing high-risk percutaneous transluminal coronary angioplasty
    • Bittl J.A. Clinical trials of Hirulog in patients undergoing high-risk percutaneous transluminal coronary angioplasty. Coron. Artery Dis. 7 (1996) 449-454
    • (1996) Coron. Artery Dis. , vol.7 , pp. 449-454
    • Bittl, J.A.1
  • 20
    • 0028870027 scopus 로고
    • A comparative review of the adverse effect profiles of heparins and heparinoids
    • Borris L.C., and Lassen M.R. A comparative review of the adverse effect profiles of heparins and heparinoids. Drug Saf. 12 (1995) 26-31
    • (1995) Drug Saf. , vol.12 , pp. 26-31
    • Borris, L.C.1    Lassen, M.R.2
  • 21
    • 0023064231 scopus 로고
    • Warfarin and the biochemistry of the vitamin K dependent proteins
    • Bovill E.G., and Mann K. Warfarin and the biochemistry of the vitamin K dependent proteins. Adv. Exp. Med. Biol. 214 (1987) 17-46
    • (1987) Adv. Exp. Med. Biol. , vol.214 , pp. 17-46
    • Bovill, E.G.1    Mann, K.2
  • 22
    • 0028835345 scopus 로고
    • Isolation and functional characterization of DNA-derived aptamers that act as thrombin inhibitors in human platelets and coagulation assays
    • Bracht F., and Schror K. Isolation and functional characterization of DNA-derived aptamers that act as thrombin inhibitors in human platelets and coagulation assays. Agents Actions 45 Suppl. (1995) 315-322
    • (1995) Agents Actions , vol.45 , Issue.SUPPL , pp. 315-322
    • Bracht, F.1    Schror, K.2
  • 23
    • 0030894354 scopus 로고    scopus 로고
    • Thrombin receptor antagonists: A work in progress
    • Brass L.F. Thrombin receptor antagonists: A work in progress. Coron. Artery Dis. 8 (1997) 49-58
    • (1997) Coron. Artery Dis. , vol.8 , pp. 49-58
    • Brass, L.F.1
  • 24
    • 0030877837 scopus 로고    scopus 로고
    • Signaling through G proteins in platelets: To the integrins and beyond
    • Brass L.F., Manning D.R., Cichowski K., and Abrams C.S. Signaling through G proteins in platelets: To the integrins and beyond. Thromb. Haemost. 78 (1997) 581-589
    • (1997) Thromb. Haemost. , vol.78 , pp. 581-589
    • Brass, L.F.1    Manning, D.R.2    Cichowski, K.3    Abrams, C.S.4
  • 25
    • 0028932993 scopus 로고
    • Tissue factor pathway inhibitor and the revised theory of coagulation
    • Broze Jr. G.J. Tissue factor pathway inhibitor and the revised theory of coagulation. Annu. Rev. Med. 46 (1995) 103-112
    • (1995) Annu. Rev. Med. , vol.46 , pp. 103-112
    • Broze Jr., G.J.1
  • 26
    • 0343307015 scopus 로고    scopus 로고
    • Recombinant endothelial nitric oxide synthase-transduced human saphenous veins: Gene therapy to augment nitric oxide production in bypass conduits
    • Cable D.G., O'Brien T., Schaff H.V., and Pompili V.J. Recombinant endothelial nitric oxide synthase-transduced human saphenous veins: Gene therapy to augment nitric oxide production in bypass conduits. Circulation 96 (1997) 173-178
    • (1997) Circulation , vol.96 , pp. 173-178
    • Cable, D.G.1    O'Brien, T.2    Schaff, H.V.3    Pompili, V.J.4
  • 27
    • 0000593528 scopus 로고
    • Studies on hemorrhagic sweet clover disease: Isolation and crystalization of the hemorrhagic agent
    • Campbell H.A., and Link K.P. Studies on hemorrhagic sweet clover disease: Isolation and crystalization of the hemorrhagic agent. J. Biol. Chem. 138 (1929) 21-33
    • (1929) J. Biol. Chem. , vol.138 , pp. 21-33
    • Campbell, H.A.1    Link, K.P.2
  • 28
    • 0027449969 scopus 로고
    • Shear induced platelet aggregation is potentiated by desmopressin and inhibited by ticlopidine
    • Cattaneo M., Lombardi R., Bettega D., Lecchi A., and Mannucci P.M. Shear induced platelet aggregation is potentiated by desmopressin and inhibited by ticlopidine. Arterioscler. Thromb. 13 (1993) 393-397
    • (1993) Arterioscler. Thromb. , vol.13 , pp. 393-397
    • Cattaneo, M.1    Lombardi, R.2    Bettega, D.3    Lecchi, A.4    Mannucci, P.M.5
  • 29
    • 0030844045 scopus 로고    scopus 로고
    • Direct thrombin inhibition superior to heparin during and after thrombolysis: Dose, duration and drug
    • Chesebro J.H. Direct thrombin inhibition superior to heparin during and after thrombolysis: Dose, duration and drug. Circulation 96 (1997) 2118-2120
    • (1997) Circulation , vol.96 , pp. 2118-2120
    • Chesebro, J.H.1
  • 30
    • 0026322267 scopus 로고
    • Proton NMR assignments and secondary structure of the snake venom protein echistatin
    • Chen Y., Pitzenberger S.M., Garsky V.M., Lumma P.K., Sanyal G., and Baum J. Proton NMR assignments and secondary structure of the snake venom protein echistatin. Biochemistry 30 (1991) 11625-11636
    • (1991) Biochemistry , vol.30 , pp. 11625-11636
    • Chen, Y.1    Pitzenberger, S.M.2    Garsky, V.M.3    Lumma, P.K.4    Sanyal, G.5    Baum, J.6
  • 31
    • 0024414475 scopus 로고
    • Structure and activity of heparin and its fragments: An overview
    • Choay J. Structure and activity of heparin and its fragments: An overview. Semin. Thromb. Hemost. 15 (1989) 359-364
    • (1989) Semin. Thromb. Hemost. , vol.15 , pp. 359-364
    • Choay, J.1
  • 32
    • 0025951849 scopus 로고
    • Chimeric antithrombin peptide. Characterization of an Arg-Gly-Asp (RGD)- and hirudin carboxyl terminus-containing synthetic peptides
    • Church F.C., Phillips J.E., and Woods J.L. Chimeric antithrombin peptide. Characterization of an Arg-Gly-Asp (RGD)- and hirudin carboxyl terminus-containing synthetic peptides. J. Biol. Chem. 266 (1991) 11975-11979
    • (1991) J. Biol. Chem. , vol.266 , pp. 11975-11979
    • Church, F.C.1    Phillips, J.E.2    Woods, J.L.3
  • 33
    • 0021965983 scopus 로고
    • A new murine monoclonal antibody reports an activation-dependent change in the conformation and/or microenvironment of the platelet glycoprotein Ilb/IIIa complex
    • Coller B.S. A new murine monoclonal antibody reports an activation-dependent change in the conformation and/or microenvironment of the platelet glycoprotein Ilb/IIIa complex. J. Clin. Invest. 76 (1985) 101-108
    • (1985) J. Clin. Invest. , vol.76 , pp. 101-108
    • Coller, B.S.1
  • 34
    • 0028876339 scopus 로고
    • Blockade of platelet GPIIb/IIIa receptors as an antithrombotic strategy
    • Coller B.S. Blockade of platelet GPIIb/IIIa receptors as an antithrombotic strategy. Circulation 92 (1995) 2373-2380
    • (1995) Circulation , vol.92 , pp. 2373-2380
    • Coller, B.S.1
  • 35
    • 0001439490 scopus 로고
    • Cholesterinstoffwechsel in Huhneriern and Hunchen
    • Dam H. Cholesterinstoffwechsel in Huhneriern and Hunchen. Biochem. Zeit 215 (1929) 475-492
    • (1929) Biochem. Zeit , vol.215 , pp. 475-492
    • Dam, H.1
  • 36
    • 0022977122 scopus 로고
    • Role of ternary complexes, in which heparin binds both antithrombin and proteinase, in the acceleration of the reactions between antithrombin and thrombin or factor Xa
    • Danielsson A., Raub E., Lindahl U., and Bjork I. Role of ternary complexes, in which heparin binds both antithrombin and proteinase, in the acceleration of the reactions between antithrombin and thrombin or factor Xa. J. Biol. Chem. 261 (1986) 15467-15473
    • (1986) J. Biol. Chem. , vol.261 , pp. 15467-15473
    • Danielsson, A.1    Raub, E.2    Lindahl, U.3    Bjork, I.4
  • 37
    • 0026337077 scopus 로고
    • The coagulation cascade: Initiation, maintenance and regulation
    • Davie E.W., Fujikawa K., and Kisiel W. The coagulation cascade: Initiation, maintenance and regulation. Biochemistry 30 (1991) 10363-10370
    • (1991) Biochemistry , vol.30 , pp. 10363-10370
    • Davie, E.W.1    Fujikawa, K.2    Kisiel, W.3
  • 38
    • 0031744875 scopus 로고    scopus 로고
    • Proteinase-activated receptors: Novel mechanisms of signaling by serine proteases
    • Dery O., Corvera C.U., Steinhoff M., and Bunnett N.W. Proteinase-activated receptors: Novel mechanisms of signaling by serine proteases. Am. J. Physiol. C274 (1998) 1429-1452
    • (1998) Am. J. Physiol. , vol.C274 , pp. 1429-1452
    • Dery, O.1    Corvera, C.U.2    Steinhoff, M.3    Bunnett, N.W.4
  • 39
    • 0030872898 scopus 로고    scopus 로고
    • The structural basis of function of the TF-VIIa complex in the cellular initiation of coagulation
    • Edgington T.S., Dickinson C.D., and Ruf W. The structural basis of function of the TF-VIIa complex in the cellular initiation of coagulation. Thromb. Haemost. 78 (1997) 401-405
    • (1997) Thromb. Haemost. , vol.78 , pp. 401-405
    • Edgington, T.S.1    Dickinson, C.D.2    Ruf, W.3
  • 40
    • 1842369101 scopus 로고    scopus 로고
    • Platelet glycoprotein IIb/IIIa receptor blockade and lowdose heparin during percutaneous coronary revascularization
    • The EPILOG Investigators. Platelet glycoprotein IIb/IIIa receptor blockade and lowdose heparin during percutaneous coronary revascularization. N. Engl J. Med. 336 (1997) 1689-1696
    • (1997) N. Engl J. Med. , vol.336 , pp. 1689-1696
    • The EPILOG Investigators1
  • 41
    • 0030590746 scopus 로고    scopus 로고
    • CAPRIE steering committee: A randomized, blinded trial of clopidogrel versus aspirin in patients at risk of ischemic events
    • Gent M. CAPRIE steering committee: A randomized, blinded trial of clopidogrel versus aspirin in patients at risk of ischemic events. Lancet 348 (1996) 1329-1339
    • (1996) Lancet , vol.348 , pp. 1329-1339
    • Gent, M.1
  • 43
    • 0028037517 scopus 로고
    • Randomized trial of intravenous heparin versus recombinant hirudin for acute coronary syndromes
    • The Global Use of Strategies to Open Occluded Coronary Arteries (GUSTO) IIa Investigators. Randomized trial of intravenous heparin versus recombinant hirudin for acute coronary syndromes. Circulation 90 (1994) 1631-1637
    • (1994) Circulation , vol.90 , pp. 1631-1637
  • 44
    • 0031883697 scopus 로고    scopus 로고
    • Pharmacology and therapeutic applications of hirudin, a new anticoagulant
    • Glusa E. Pharmacology and therapeutic applications of hirudin, a new anticoagulant. Kidney Int. 64 (1998) S54-S56
    • (1998) Kidney Int. , vol.64
    • Glusa, E.1
  • 46
    • 0026681422 scopus 로고
    • Iloprost: A review of its pharmacodynamic and pharmacokinetic properties and therapeutic potential in peripheral vascular disease, myocardial ischaemia and extracorporeal circulation procedures
    • Grant S.M., and Goa K.L. Iloprost: A review of its pharmacodynamic and pharmacokinetic properties and therapeutic potential in peripheral vascular disease, myocardial ischaemia and extracorporeal circulation procedures. Drugs 43 (1992) 889-924
    • (1992) Drugs , vol.43 , pp. 889-924
    • Grant, S.M.1    Goa, K.L.2
  • 47
    • 0026032110 scopus 로고
    • Thromboxane synthase inhibitors, thromboxane receptor antagonists and dual blockers in thrombotic disorders
    • Gresele P., Deckmyn H., Nenci G.G., and Vermylen J. Thromboxane synthase inhibitors, thromboxane receptor antagonists and dual blockers in thrombotic disorders. Trends Pharmacol. Sci. 12 (1991) 158-166
    • (1991) Trends Pharmacol. Sci. , vol.12 , pp. 158-166
    • Gresele, P.1    Deckmyn, H.2    Nenci, G.G.3    Vermylen, J.4
  • 48
    • 0027886337 scopus 로고
    • Lack of anti-factor Xa activity in umbilical cord vein samples after subcutaneous administration of heparin or low molecular mass heparin in pregnant women
    • Harenberg J., Schneider D., Heilmann L., and Wolf H. Lack of anti-factor Xa activity in umbilical cord vein samples after subcutaneous administration of heparin or low molecular mass heparin in pregnant women. Haemostasis 23 (1993) 314-320
    • (1993) Haemostasis , vol.23 , pp. 314-320
    • Harenberg, J.1    Schneider, D.2    Heilmann, L.3    Wolf, H.4
  • 50
    • 0024396437 scopus 로고
    • A randomized trial comparing ticlopidine hydrochloride with aspirin for the prevention of stroke in high-risk patients: Ticlopidine Aspirin Stroke Study
    • Hass W.K., Easton J.D., Adams H.P., Pryse-Phillips W., Molony B.A., Anderson S., and Kamm B. A randomized trial comparing ticlopidine hydrochloride with aspirin for the prevention of stroke in high-risk patients: Ticlopidine Aspirin Stroke Study. N. Engl J. Med. 321 (1989) 501-507
    • (1989) N. Engl J. Med. , vol.321 , pp. 501-507
    • Hass, W.K.1    Easton, J.D.2    Adams, H.P.3    Pryse-Phillips, W.4    Molony, B.A.5    Anderson, S.6    Kamm, B.7
  • 51
    • 0028913021 scopus 로고
    • Optimal intensity and monitoring warfarin
    • Hirsh J. Optimal intensity and monitoring warfarin. Am. J. Cardiol. 75 (1995) 39B-42B
    • (1995) Am. J. Cardiol. , vol.75
    • Hirsh, J.1
  • 52
    • 0028786997 scopus 로고
    • Oral anticoagulants. Mechanism of action, clinical effectiveness and optimal therapeutic range
    • Hirsh J., Dalen J.E., Deykin D., Poller L., and Bussey H. Oral anticoagulants. Mechanism of action, clinical effectiveness and optimal therapeutic range. Chest 108 (1995) 231S-246S
    • (1995) Chest , vol.108
    • Hirsh, J.1    Dalen, J.E.2    Deykin, D.3    Poller, L.4    Bussey, H.5
  • 53
    • 0021967186 scopus 로고
    • Rationale behind the development of low molecular weight heparin derivatives
    • Hirsh J., Ofosu F., and Buchanan M. Rationale behind the development of low molecular weight heparin derivatives. Semin. Thromb. Hemost. 11 (1985) 13-16
    • (1985) Semin. Thromb. Hemost. , vol.11 , pp. 13-16
    • Hirsh, J.1    Ofosu, F.2    Buchanan, M.3
  • 55
    • 0030874820 scopus 로고    scopus 로고
    • Effects of locally administered argatroban on restenosis after balloon angioplasty: Experimental and clinical study
    • Imanishi T., Arita M., Tomobuchi Y., Hamada M., Hano T., and Nishio I. Effects of locally administered argatroban on restenosis after balloon angioplasty: Experimental and clinical study. Clin. Exp. Pharmacol. Physiol. 24 (1997) 800-806
    • (1997) Clin. Exp. Pharmacol. Physiol. , vol.24 , pp. 800-806
    • Imanishi, T.1    Arita, M.2    Tomobuchi, Y.3    Hamada, M.4    Hano, T.5    Nishio, I.6
  • 56
    • 77956827307 scopus 로고    scopus 로고
    • Low-molecular weight heparin: Prophylaxis of venous thrombosis
    • Loscalzo S., and Loscalzo J. (Eds), Marcel Dekker, New York
    • Kakar V.V. Low-molecular weight heparin: Prophylaxis of venous thrombosis. In: Loscalzo S., and Loscalzo J. (Eds). "New Therapeutic Agents in Thrombosis and Thrombolysis" (1997), Marcel Dekker, New York 103-128
    • (1997) "New Therapeutic Agents in Thrombosis and Thrombolysis" , pp. 103-128
    • Kakar, V.V.1
  • 57
    • 0026036550 scopus 로고
    • Prostacyclin and prostaglandin E1: Molecular mechanisms and therapeutic utility
    • Kerins D.M., Murray R., and FitzGerald G.A. Prostacyclin and prostaglandin E1: Molecular mechanisms and therapeutic utility. Prog. Hemost. Thromb. 10 (1991) 307-337
    • (1991) Prog. Hemost. Thromb. , vol.10 , pp. 307-337
    • Kerins, D.M.1    Murray, R.2    FitzGerald, G.A.3
  • 58
    • 41749122243 scopus 로고
    • Hepartin: Chemistry and clinical usage; chemical structure of heparin
    • Kakker V.V., and Thomas D.P. (Eds), Academic Press, London
    • Kiss J. Hepartin: Chemistry and clinical usage; chemical structure of heparin. In: Kakker V.V., and Thomas D.P. (Eds). "Heparin: Chemistry and Clinical Usage" (1977), Academic Press, London 3-20
    • (1977) "Heparin: Chemistry and Clinical Usage" , pp. 3-20
    • Kiss, J.1
  • 59
  • 60
    • 0030738122 scopus 로고    scopus 로고
    • Evidence for prevention of death and myocardial infarction with platelet membrane glycoprotein IIb/IIIa receptor blockade by abciximab (c7E3 Fab) among patients with unstable angina undergoing percutaneous coronary revascularization: EPIC Investigators: Evaluation of 7E3 in preventing Ischemic Complications
    • Lincoff A.M., Califf R.M., Anderson K.M., Weisman H.F., Aguirre F.V., Kleiman N.S., Harrington R.A., and Topol E.J. Evidence for prevention of death and myocardial infarction with platelet membrane glycoprotein IIb/IIIa receptor blockade by abciximab (c7E3 Fab) among patients with unstable angina undergoing percutaneous coronary revascularization: EPIC Investigators: Evaluation of 7E3 in preventing Ischemic Complications. J. Am. Coll. Cardiol. 30 (1997) 149-156
    • (1997) J. Am. Coll. Cardiol. , vol.30 , pp. 149-156
    • Lincoff, A.M.1    Califf, R.M.2    Anderson, K.M.3    Weisman, H.F.4    Aguirre, F.V.5    Kleiman, N.S.6    Harrington, R.A.7    Topol, E.J.8
  • 61
    • 0024570624 scopus 로고
    • Therapeutic effectiveness of prostaglandins (PGs) in peripheral vascular disease (PVD)
    • Linet O.L., and Mohberg N.R. Therapeutic effectiveness of prostaglandins (PGs) in peripheral vascular disease (PVD). Adv. Prostaglandin Thromboxane Leukot. Res. 19 (1989) 307-310
    • (1989) Adv. Prostaglandin Thromboxane Leukot. Res. , vol.19 , pp. 307-310
    • Linet, O.L.1    Mohberg, N.R.2
  • 62
    • 0028274014 scopus 로고
    • The platelet glycoprotein Ib-IX complex
    • Lopez J.A. The platelet glycoprotein Ib-IX complex. Blood Coagul. Fibrinolysis 5 (1994) 97-119
    • (1994) Blood Coagul. Fibrinolysis , vol.5 , pp. 97-119
    • Lopez, J.A.1
  • 63
    • 0031814242 scopus 로고    scopus 로고
    • Adverse haematological effects of ticlopidine: Prevention, recognition and management
    • Love B.B., Biller J., and Gent M. Adverse haematological effects of ticlopidine: Prevention, recognition and management. Drug Saf. 19 (1998) 89-98
    • (1998) Drug Saf. , vol.19 , pp. 89-98
    • Love, B.B.1    Biller, J.2    Gent, M.3
  • 66
    • 0027749258 scopus 로고
    • Pre-clinical and clinical studies on Hirulog: A potent and specific direct thrombin inhibitor
    • Maraganore J.M. Pre-clinical and clinical studies on Hirulog: A potent and specific direct thrombin inhibitor. Adv. Exp. Med. Biol. 340 (1993) 227-236
    • (1993) Adv. Exp. Med. Biol. , vol.340 , pp. 227-236
    • Maraganore, J.M.1
  • 67
    • 0025346345 scopus 로고
    • Design and characterization of hirulogs: A novel class of bivalent peptide inhibitors of thrombin
    • Maraganore J.M., Bourdon P., Jablonski J., Ramachandran K.L., and Fenton II J.W. Design and characterization of hirulogs: A novel class of bivalent peptide inhibitors of thrombin. Biochemistry 29 (1990) 7095-7101
    • (1990) Biochemistry , vol.29 , pp. 7095-7101
    • Maraganore, J.M.1    Bourdon, P.2    Jablonski, J.3    Ramachandran, K.L.4    Fenton II, J.W.5
  • 69
    • 0027968823 scopus 로고
    • The development of hirudin as an antithrombotic drug
    • Markwardt F. The development of hirudin as an antithrombotic drug. Thromb. Res. 74 (1994) 1-23
    • (1994) Thromb. Res. , vol.74 , pp. 1-23
    • Markwardt, F.1
  • 70
    • 0026773026 scopus 로고
    • Clinical application of the synthetic thrombin inhibitor, argatroban (MD-805)
    • Matsuo T., Kario K., Kodama K., and Okamoto S. Clinical application of the synthetic thrombin inhibitor, argatroban (MD-805). Semin. Thromb. Hemost. 18 (1992) 155-160
    • (1992) Semin. Thromb. Hemost. , vol.18 , pp. 155-160
    • Matsuo, T.1    Kario, K.2    Kodama, K.3    Okamoto, S.4
  • 71
    • 0031427237 scopus 로고    scopus 로고
    • Development of argatroban, a direct thrombin inhibitor and its clinical application
    • Matsuo T., Koide M., and Kario K. Development of argatroban, a direct thrombin inhibitor and its clinical application. Semin. Thromb. Hemost. 23 (1997) 517-522
    • (1997) Semin. Thromb. Hemost. , vol.23 , pp. 517-522
    • Matsuo, T.1    Koide, M.2    Kario, K.3
  • 72
    • 0029610823 scopus 로고
    • Heparin binding to platelet factor-4: An NMR and site-directed mutagenesis study: Arginine residues are crucial for binding
    • Mayo K.H., Ilyina E., Roongta V., Dundas M., Joseph J., Lai C.K., Maione T., and Daly T.J. Heparin binding to platelet factor-4: An NMR and site-directed mutagenesis study: Arginine residues are crucial for binding. Biochem. J. 312 (1995) 357-365
    • (1995) Biochem. J. , vol.312 , pp. 357-365
    • Mayo, K.H.1    Ilyina, E.2    Roongta, V.3    Dundas, M.4    Joseph, J.5    Lai, C.K.6    Maione, T.7    Daly, T.J.8
  • 73
    • 0026713927 scopus 로고
    • Antithrombin III: Physiology, deficiency and replacement therapy
    • Menache D., Grossman B.J., and Jackson C.M. Antithrombin III: Physiology, deficiency and replacement therapy. Transfusion 32 (1992) 580-588
    • (1992) Transfusion , vol.32 , pp. 580-588
    • Menache, D.1    Grossman, B.J.2    Jackson, C.M.3
  • 74
    • 0023908222 scopus 로고
    • Shear-induced platelet aggregation can be mediated by vWF released from platelets, as well as by exogenous large or unusually large vWF multimers, requires adenosine diphosphate and is resistant to aspirin
    • Moake J.L., Turner N.A., Stathopoulos N.A., Nolasco L., and Hellums J.D. Shear-induced platelet aggregation can be mediated by vWF released from platelets, as well as by exogenous large or unusually large vWF multimers, requires adenosine diphosphate and is resistant to aspirin. Blood 71 (1988) 1366-1374
    • (1988) Blood , vol.71 , pp. 1366-1374
    • Moake, J.L.1    Turner, N.A.2    Stathopoulos, N.A.3    Nolasco, L.4    Hellums, J.D.5
  • 75
    • 0028062665 scopus 로고
    • History of drugs for thrombotic disease: Discovery, development and directions for the future
    • Mueller R.L., and Scheidt S. History of drugs for thrombotic disease: Discovery, development and directions for the future. Circulation 89 (1994) 432-449
    • (1994) Circulation , vol.89 , pp. 432-449
    • Mueller, R.L.1    Scheidt, S.2
  • 76
    • 0342872079 scopus 로고    scopus 로고
    • Profound and sustained inhibition of platelet aggregation by Fradafiban, a nonpeptide platelet glycoprotein IIb/IIIa antagonist and its orally active prodrug, Lefradafiban, in men
    • Muller T.H., Weisenberger H., Brickl R., Narjes H., Himmelsbach F., and Krause J. Profound and sustained inhibition of platelet aggregation by Fradafiban, a nonpeptide platelet glycoprotein IIb/IIIa antagonist and its orally active prodrug, Lefradafiban, in men. Circulation 96 (1997) 1130-1138
    • (1997) Circulation , vol.96 , pp. 1130-1138
    • Muller, T.H.1    Weisenberger, H.2    Brickl, R.3    Narjes, H.4    Himmelsbach, F.5    Krause, J.6
  • 77
    • 0016259925 scopus 로고
    • The mode of action of vitamin K: Identification of gamma-carboxyglutamic acid as a component of prothrombin
    • Nelsestuen G.L., Zytkovicz T.H., and Howard J.B. The mode of action of vitamin K: Identification of gamma-carboxyglutamic acid as a component of prothrombin. J. Biol. Chem. 249 (1974) 6347-6350
    • (1974) J. Biol. Chem. , vol.249 , pp. 6347-6350
    • Nelsestuen, G.L.1    Zytkovicz, T.H.2    Howard, J.B.3
  • 81
    • 0032560628 scopus 로고    scopus 로고
    • International, randomized, controlled trial of lamifiban (a platelet glycoprotein Ilb/IIIa inhibitor), heparin, or both in unstable angina: Platelet Ilb/IIIa Antagonism for the Reduction of Acute coronary syndrome events in a Global Organization Network
    • The PARAGON Investigators. International, randomized, controlled trial of lamifiban (a platelet glycoprotein Ilb/IIIa inhibitor), heparin, or both in unstable angina: Platelet Ilb/IIIa Antagonism for the Reduction of Acute coronary syndrome events in a Global Organization Network. Circulation 97 (1998) 2386-2395
    • (1998) Circulation , vol.97 , pp. 2386-2395
    • The PARAGON Investigators1
  • 82
    • 0025609172 scopus 로고
    • Thromboxane A2/prostaglandin H2 receptor antagonists: A new therapeutic principle
    • Patscheke H. Thromboxane A2/prostaglandin H2 receptor antagonists: A new therapeutic principle. Stroke 21 (1990) 139-142
    • (1990) Stroke , vol.21 , pp. 139-142
    • Patscheke, H.1
  • 85
    • 2642654221 scopus 로고    scopus 로고
    • A comparison of aspirin plus tirofiban with aspirin plus heparin for unstable angina
    • Platelet Receptor Inhibition in Ischemic Syndrome Management (PRISM) Study Investigators. A comparison of aspirin plus tirofiban with aspirin plus heparin for unstable angina. N. Engl. J. Med. 338 (1998) 1498-1505
    • (1998) N. Engl. J. Med. , vol.338 , pp. 1498-1505
  • 86
    • 2642599026 scopus 로고    scopus 로고
    • Inhibition of the platelet glycoprotein IIb/Illa receptor with tirofiban in unstable angina and non-Q-wave myocardial infarction: Platelet Receptor Inhibition in Ischemic Syndrome Management in Patients Limited by Unstable Signs and Symptoms
    • (PRISM-PLUS) Study Investigators. Inhibition of the platelet glycoprotein IIb/Illa receptor with tirofiban in unstable angina and non-Q-wave myocardial infarction: Platelet Receptor Inhibition in Ischemic Syndrome Management in Patients Limited by Unstable Signs and Symptoms. N. Engl. J. Med. 338 (1998) 1488-1497
    • (1998) N. Engl. J. Med. , vol.338 , pp. 1488-1497
    • (PRISM-PLUS) Study Investigators1
  • 89
    • 0028140168 scopus 로고
    • Randomized trial of ridogrel, a combine thromboxane A2 synthase inhibitor and thromboxane A2/prostaglandin endoperoxide receptor antagonist, versus aspirin as adjunct to thrombolysis in patients with acute myocardial infarction
    • The RAPT Investigators. Randomized trial of ridogrel, a combine thromboxane A2 synthase inhibitor and thromboxane A2/prostaglandin endoperoxide receptor antagonist, versus aspirin as adjunct to thrombolysis in patients with acute myocardial infarction. Circulation 89 (1994) 588-595
    • (1994) Circulation , vol.89 , pp. 588-595
    • The RAPT Investigators1
  • 90
    • 0027742657 scopus 로고
    • Cellular activation by thromboxane A2 and other eicosanoids
    • Reilly M., and Fitzgerald G.A. Cellular activation by thromboxane A2 and other eicosanoids. Eur. Heart J. 14 (1993) 88-93
    • (1993) Eur. Heart J. , vol.14 , pp. 88-93
    • Reilly, M.1    Fitzgerald, G.A.2
  • 92
    • 0029160806 scopus 로고
    • Advances in antithrombotic drug therapy for coronary artery disease
    • Rihal C.S., Flather M., Hirsh J., and Yusuf S. Advances in antithrombotic drug therapy for coronary artery disease. Eur. Heart J. 16 (1995) 10-21
    • (1995) Eur. Heart J. , vol.16 , pp. 10-21
    • Rihal, C.S.1    Flather, M.2    Hirsh, J.3    Yusuf, S.4
  • 93
    • 0018353621 scopus 로고
    • Molecular weight determination of commercial heparin sodium USP and its sterile solutions
    • Rodriguez H.J., and Vanderwielen A.J. Molecular weight determination of commercial heparin sodium USP and its sterile solutions. J. Pharm. Sci. 68 (1979) 588-591
    • (1979) J. Pharm. Sci. , vol.68 , pp. 588-591
    • Rodriguez, H.J.1    Vanderwielen, A.J.2
  • 94
    • 0022005826 scopus 로고
    • Role of heparin and heparinlike molecules in thrombosis and atherosclerosis
    • Rosenberg R.D. Role of heparin and heparinlike molecules in thrombosis and atherosclerosis. Fed. Proc. Am. Sci. 44 (1985) 404-409
    • (1985) Fed. Proc. Am. Sci. , vol.44 , pp. 404-409
    • Rosenberg, R.D.1
  • 95
    • 0028118792 scopus 로고
    • Aspirin, platelets and thrombosis: Theory and practice
    • Roth G.J., and Calverley D.C. Aspirin, platelets and thrombosis: Theory and practice. Blood 83 (1994) 885-898
    • (1994) Blood , vol.83 , pp. 885-898
    • Roth, G.J.1    Calverley, D.C.2
  • 96
    • 0028245488 scopus 로고
    • Glycoprotein Ib and von Willebrand factor in the process of thrombus formation
    • Ruggeri Z.M., and Ann N.Y. Glycoprotein Ib and von Willebrand factor in the process of thrombus formation. Acad. Sci. 18 (1994) 200-210
    • (1994) Acad. Sci. , vol.18 , pp. 200-210
    • Ruggeri, Z.M.1    Ann, N.Y.2
  • 98
    • 0025866812 scopus 로고
    • Refined structure of the hirudin-thrombin complex
    • Rydel T.J., Tulinsky A., Bode W., and Huber R. Refined structure of the hirudin-thrombin complex. J. Mol. Biol. 221 (1991) 583-601
    • (1991) J. Mol. Biol. , vol.221 , pp. 583-601
    • Rydel, T.J.1    Tulinsky, A.2    Bode, W.3    Huber, R.4
  • 99
    • 0030462546 scopus 로고    scopus 로고
    • New data on the pharmacology of heparin and low molecular weight heparins
    • Samama M.M., Bara L., and Gouin-Thibault I. New data on the pharmacology of heparin and low molecular weight heparins. Drugs 52 (1996) 8-14
    • (1996) Drugs , vol.52 , pp. 8-14
    • Samama, M.M.1    Bara, L.2    Gouin-Thibault, I.3
  • 100
    • 0023778170 scopus 로고
    • Heparin induces release of extrinsic coagulation pathway inhibitor (EPI)
    • Sandset P.M., Abildgaard U., and Larsen M.L. Heparin induces release of extrinsic coagulation pathway inhibitor (EPI). Thromb. Res. 50 (1988) 803-813
    • (1988) Thromb. Res. , vol.50 , pp. 803-813
    • Sandset, P.M.1    Abildgaard, U.2    Larsen, M.L.3
  • 102
    • 0029009904 scopus 로고
    • Antiplatelet drugs: A comparative review
    • Schror K. Antiplatelet drugs: A comparative review. Drugs 50 (1995) 7-28
    • (1995) Drugs , vol.50 , pp. 7-28
    • Schror, K.1
  • 103
    • 0030852046 scopus 로고    scopus 로고
    • Aspirin and platelets: The antiplatelet action of aspirin and its role in thrombosis treatment and prophylaxis
    • Schror K. Aspirin and platelets: The antiplatelet action of aspirin and its role in thrombosis treatment and prophylaxis. Semin. Thromb. Hemost. 23 (1997) 349-356
    • (1997) Semin. Thromb. Hemost. , vol.23 , pp. 349-356
    • Schror, K.1
  • 104
    • 0032168873 scopus 로고    scopus 로고
    • The antiplatelet effects of ticlopidine and clopidogrel
    • Sharis P.J., Cannon C.P., and Loscalzo J. The antiplatelet effects of ticlopidine and clopidogrel. Ann. Intern. Med. 129 (1998) 394-405
    • (1998) Ann. Intern. Med. , vol.129 , pp. 394-405
    • Sharis, P.J.1    Cannon, C.P.2    Loscalzo, J.3
  • 105
    • 0030855793 scopus 로고    scopus 로고
    • Not just another pretty face: Regulation of platelet function at the cytoplasmic face of integrin alpha Ilb beta 3
    • Shattil S.J., Gao J., and Kashiwagi H. Not just another pretty face: Regulation of platelet function at the cytoplasmic face of integrin alpha Ilb beta 3. Thromb. Haemost. 78 (1997) 220-225
    • (1997) Thromb. Haemost. , vol.78 , pp. 220-225
    • Shattil, S.J.1    Gao, J.2    Kashiwagi, H.3
  • 106
    • 0032523064 scopus 로고    scopus 로고
    • Integrin signaling: The platelet paradigm
    • Shattil S.J., Kashiwagi H., and Pampori N. Integrin signaling: The platelet paradigm. Blood 91 (1998) 2645-2657
    • (1998) Blood , vol.91 , pp. 2645-2657
    • Shattil, S.J.1    Kashiwagi, H.2    Pampori, N.3
  • 108
    • 0000376008 scopus 로고
    • Vitamin K dependent modifications of glutamic acid residues in prothrombin
    • Stenflo J., Ferlund P., Egan W., and Roepstorff P. Vitamin K dependent modifications of glutamic acid residues in prothrombin. Proc. Natl. Acad. Sci. USA 71 (1974) 2730-2733
    • (1974) Proc. Natl. Acad. Sci. USA , vol.71 , pp. 2730-2733
    • Stenflo, J.1    Ferlund, P.2    Egan, W.3    Roepstorff, P.4
  • 109
    • 0027499804 scopus 로고
    • Synthesis of vitamin K-dependent proteins
    • Suttie J.W. Synthesis of vitamin K-dependent proteins. FASEB J. 7 (1993) 445-452
    • (1993) FASEB J. , vol.7 , pp. 445-452
    • Suttie, J.W.1
  • 110
    • 0029798675 scopus 로고    scopus 로고
    • Glycoprotein IIb/IIIa receptor inhibitors: Putting the EPIC, IMPACT II, RESTORE and EPILOG trials into perspective
    • Tcheng J.E. Glycoprotein IIb/IIIa receptor inhibitors: Putting the EPIC, IMPACT II, RESTORE and EPILOG trials into perspective. Am. J. Cardiol. 78 (1996) 35-40
    • (1996) Am. J. Cardiol. , vol.78 , pp. 35-40
    • Tcheng, J.E.1
  • 111
    • 0028930680 scopus 로고
    • Multicenter, randomized, double-blind, placebo-controlled trial of the platelet integrin glycoprotein IIb/IIIa blocker Integrilin in elective coronary intervention: IMPACT Investigators
    • Tcheng J.E., Harrington R.A., Kottke-Marchant K., Kleiman N.S., Ellis S.G., Kereiakes D.J., Mick M.J., Navetta F.I., Smith J.E., Worley S.J., et al. Multicenter, randomized, double-blind, placebo-controlled trial of the platelet integrin glycoprotein IIb/IIIa blocker Integrilin in elective coronary intervention: IMPACT Investigators. Circulation 91 (1995) 2151-2157
    • (1995) Circulation , vol.91 , pp. 2151-2157
    • Tcheng, J.E.1    Harrington, R.A.2    Kottke-Marchant, K.3    Kleiman, N.S.4    Ellis, S.G.5    Kereiakes, D.J.6    Mick, M.J.7    Navetta, F.I.8    Smith, J.E.9    Worley, S.J.10
  • 112
    • 0020548878 scopus 로고
    • Protection of factor Xa from neutralization by the heparin-antithrombin complex
    • Teitel J.M., and Rosenberg R. Protection of factor Xa from neutralization by the heparin-antithrombin complex. J. Clin. Invest. 71 (1983) 1383-1391
    • (1983) J. Clin. Invest. , vol.71 , pp. 1383-1391
    • Teitel, J.M.1    Rosenberg, R.2
  • 113
    • 0021866520 scopus 로고
    • Anticoagulant effects of a low molecular weight heparinoid (Org 10172) in human volunteers and haemodialysis patients
    • ten Cate H., Henny C.P., ten Cate J.W., Buller H.R., Mooy M.C., Surachno S., and Wilmink J.M. Anticoagulant effects of a low molecular weight heparinoid (Org 10172) in human volunteers and haemodialysis patients. Thromb. Res. 39 (1985) 211-222
    • (1985) Thromb. Res. , vol.39 , pp. 211-222
    • ten Cate, H.1    Henny, C.P.2    ten Cate, J.W.3    Buller, H.R.4    Mooy, M.C.5    Surachno, S.6    Wilmink, J.M.7
  • 116
    • 0030982146 scopus 로고    scopus 로고
    • Mechanism of action of aspirin-like drugs
    • Vane J.R., and Botting R.M. Mechanism of action of aspirin-like drugs. Semin. Arthritis Rheum. 26 (1997) 2-10
    • (1997) Semin. Arthritis Rheum. , vol.26 , pp. 2-10
    • Vane, J.R.1    Botting, R.M.2
  • 117
    • 0025276269 scopus 로고
    • A new low molecular weight heparinoid Org 10172 as anticoagulant in hemodialysis
    • Von Bonsdorff M., Stiekema J., Harjanne A., and Alapiessa U. A new low molecular weight heparinoid Org 10172 as anticoagulant in hemodialysis. Int. J. Artif. Organs 13 (1990) 103-108
    • (1990) Int. J. Artif. Organs , vol.13 , pp. 103-108
    • Von Bonsdorff, M.1    Stiekema, J.2    Harjanne, A.3    Alapiessa, U.4
  • 118
    • 0024438178 scopus 로고
    • Development of recombinant hirudin as a therapeutic anticoagulant and antithrombotic agent: Some objective considerations
    • Walenga J.M., Pifarre R., Hoppensteadt D.A., and Fareed J. Development of recombinant hirudin as a therapeutic anticoagulant and antithrombotic agent: Some objective considerations. Semin. Thromb. Hemost. 15 (1989) 316-333
    • (1989) Semin. Thromb. Hemost. , vol.15 , pp. 316-333
    • Walenga, J.M.1    Pifarre, R.2    Hoppensteadt, D.A.3    Fareed, J.4
  • 119
    • 0028884858 scopus 로고
    • Anti-platelet monoclonal antibodies for the prevention of arterial thrombosis: Experience with ReoPro, a monoclonal antibody directed against the platelet GPIIb/IIIa receptor
    • Weisman H.F., Schaible T.F., Jordan R.E., Cabot C.F., and Anderson K.M. Anti-platelet monoclonal antibodies for the prevention of arterial thrombosis: Experience with ReoPro, a monoclonal antibody directed against the platelet GPIIb/IIIa receptor. Biochem. Soc. Trans. 23 (1995) 1051-1057
    • (1995) Biochem. Soc. Trans. , vol.23 , pp. 1051-1057
    • Weisman, H.F.1    Schaible, T.F.2    Jordan, R.E.3    Cabot, C.F.4    Anderson, K.M.5
  • 120
    • 0031936090 scopus 로고    scopus 로고
    • Thrombin binds to soluble fibrin degradation products where it is protected from inhibition by heparin-antithrombin but susceptible to inactivation by antithrombin-independent inhibitors
    • Weitz J.I., Leslie B., and Hudoba M. Thrombin binds to soluble fibrin degradation products where it is protected from inhibition by heparin-antithrombin but susceptible to inactivation by antithrombin-independent inhibitors. Circulation 97 (1998) 544-552
    • (1998) Circulation , vol.97 , pp. 544-552
    • Weitz, J.I.1    Leslie, B.2    Hudoba, M.3
  • 121
    • 0030771823 scopus 로고    scopus 로고
    • Randomized, double-blind comparison of hirulog versus heparin in patients receiving streptokinase and aspirin for acute myocardial infarction (HERO): Hirulog Early Reperfusion/Occlusion (HERO) Trial Investigators
    • White H.D., Aylward P.E., Frey M.J., Adgey A.A., Nair R., Hillis W.S., Shalev Y., Brown M.A., French J.K., Collins R., Maraganore J., and Adelman B. Randomized, double-blind comparison of hirulog versus heparin in patients receiving streptokinase and aspirin for acute myocardial infarction (HERO): Hirulog Early Reperfusion/Occlusion (HERO) Trial Investigators. Circulation 96 (1997) 2155-2161
    • (1997) Circulation , vol.96 , pp. 2155-2161
    • White, H.D.1    Aylward, P.E.2    Frey, M.J.3    Adgey, A.A.4    Nair, R.5    Hillis, W.S.6    Shalev, Y.7    Brown, M.A.8    French, J.K.9    Collins, R.10    Maraganore, J.11    Adelman, B.12
  • 122
    • 0030715080 scopus 로고    scopus 로고
    • Danaparoid. A review of its pharmacology and clinical use in the management of heparin-induced thrombocytopenia
    • Wilde M.I., and Markham A. Danaparoid. A review of its pharmacology and clinical use in the management of heparin-induced thrombocytopenia. Drugs 54 (1997) 903-924
    • (1997) Drugs , vol.54 , pp. 903-924
    • Wilde, M.I.1    Markham, A.2
  • 123
    • 0031859650 scopus 로고    scopus 로고
    • Injury-coupled induction of endothelial eNOS and COX-2 genes: a paradigm for thromboresistant gene therapy
    • Wu K.K. Injury-coupled induction of endothelial eNOS and COX-2 genes: a paradigm for thromboresistant gene therapy. Proc. Assoc. Am. Physicians 110 (1998) 163-170
    • (1998) Proc. Assoc. Am. Physicians , vol.110 , pp. 163-170
    • Wu, K.K.1
  • 124
    • 0028835339 scopus 로고
    • Molecular regulation and augmentation of prostacyclin biosynthesis
    • Wu K.K. Molecular regulation and augmentation of prostacyclin biosynthesis. Agents Actions 45 Suppl. (1995) 11-17
    • (1995) Agents Actions , vol.45 , Issue.SUPPL , pp. 11-17
    • Wu, K.K.1
  • 125
    • 0026350808 scopus 로고
    • Cloning and expression of the cDNA for human gamma-glutamyl carboxylase
    • Wu S.M., Cheung W.F., Frazier D., and Stafford D.W. Cloning and expression of the cDNA for human gamma-glutamyl carboxylase. Science 254 (1991) 1634-1636
    • (1991) Science , vol.254 , pp. 1634-1636
    • Wu, S.M.1    Cheung, W.F.2    Frazier, D.3    Stafford, D.W.4
  • 126
    • 0026783807 scopus 로고
    • Tissue factor-dependent autoactivation of human blood coagulation factor VII
    • Yamamoto M., Nakagaki T., and Kisiel W. Tissue factor-dependent autoactivation of human blood coagulation factor VII. J. Biol. Chem. 267 (1992) 19089-19094
    • (1992) J. Biol. Chem. , vol.267 , pp. 19089-19094
    • Yamamoto, M.1    Nakagaki, T.2    Kisiel, W.3
  • 127
    • 0027502204 scopus 로고
    • The antithrombotic effect of low molecular weight synthetic thrombin inhibitors, argatroban and PPACK, on He-Ne laser-induced thrombosis in rat mesenteric microvessels
    • Yamashita T., Yamamoto J., Sasaki Y., and Matsuoka A. The antithrombotic effect of low molecular weight synthetic thrombin inhibitors, argatroban and PPACK, on He-Ne laser-induced thrombosis in rat mesenteric microvessels. Thromb. Res. 69 (1993) 93-100
    • (1993) Thromb. Res. , vol.69 , pp. 93-100
    • Yamashita, T.1    Yamamoto, J.2    Sasaki, Y.3    Matsuoka, A.4
  • 129
    • 0031043059 scopus 로고    scopus 로고
    • Pathophysiologic implications of membrane phospholipid asymmetry in blood cells
    • Zwaal R.F., and Schroit A.J. Pathophysiologic implications of membrane phospholipid asymmetry in blood cells. Blood 89 (1997) 1121-1132
    • (1997) Blood , vol.89 , pp. 1121-1132
    • Zwaal, R.F.1    Schroit, A.J.2


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.