Development of argatroban, a direct thrombin inhibitor, and its clinical application

Seminars in Thrombosis and Hemostasis

Volumn 23, Issue 6, 1997, Pages 517-522

  Matsuo, Takefumi ^a   Koide, Masanobu ^a   Kario, Kazuomi ^a  

^a HYOGO PREFECTURAL AWAJI HOSPITAL   (Japan)

Author keywords

Acute ischemic stroke; Argatroban; Cardiovascular disease; Monitoring; Thrombin inhibitor

Indexed keywords

ANTITHROMBIN III; ARGATROBAN; D DIMER; HEPARIN COFACTOR II; THROMBIN INHIBITOR;

ANTITHROMBIN III DEFICIENCY; CLINICAL TRIAL; CONFERENCE PAPER; CORONARY ARTERY OBSTRUCTION; DRUG EFFICACY; DRUG MONITORING; FIBRINOLYSIS; HUMAN; INTRAVENOUS DRUG ADMINISTRATION; PARTIAL THROMBOPLASTIN TIME; PERIPHERAL OCCLUSIVE ARTERY DISEASE; PRIORITY JOURNAL; STROKE; THROMBOCYTE AGGREGATION; TRANSLUMINAL CORONARY ANGIOPLASTY;

EID: 0031427237     PISSN: 00946176     EISSN: None     Source Type: Journal    
DOI: 10.1055/s-2007-996129     Document Type: Conference Paper

References (11)

1. Matsuo T, T Yamada, K Nakao: Effects of a new synthetic anticoagulant (MD805) on platelets. Acta Haematol Jpn 50:654-669, 1987.
2. Lefkovits J, EJ Topol: Direct thrombin inhibitors in cardiovascular medicine. Circulation 90:1522-1526, 1994.
3. Fukutake K, M Takeyama, K Amano, M Ueda, M Fujimaki: Clinical pharmacology of argatroban, selective anti-thrombin agent (comparative study with heparin). Cardioangiology 29: 190-195, 1991.
4. Matsuo T, T Yamada, T Yamanashi, K Kodama: Choice of anticoagulant in a congenital antithrombin III (ATIII)-deficiency patient with chronic renal failure undergoing regular haemodialysis. Clin Lab Haematol 11:213-219, 1989.
5. Kondo S, F Tokunaga, K Kario, T Matsuo, M Koide: Molecular and cellular basis for type I heparin cofactor II deficiency theparin cofactor II Awaji). Blood 87:1006-1012, 1996.
6. Matsuo T, K Kario, S Sakamoto, T Yamada, T Miki, T Hirase, H Kobayashi: Hereditary heparin cofactor II deficiency and coronary artery disease. Thromb Res 65:495-505, 1992.
7. Sakamoto S, T Hirase, S Suzuki, T Tsukamoto, T Miki, T Yamada, T Matsuo: Inhibitory effect of argatroban on thrombin-antithrombin III complex after percutaneous transluminal coronary angioplasty. Thromb Haemostas 74:801-802, 1995.
8. Suzuki S, S Sakamoto, K Adachi, K Mizutani, M Koide, N Ohga, T Miki, T Matsuo: Effect of argatroban on thrombus formation during acute coronary occlusion after balloon angioplasty. Thromb Res 77:369-373, 1995
9. Matsuo T, K Kario, S Matsuda, N Yamaguchi, E Kakishita: Effect of thrombin inhibitor on patients with peripheral arterial obstructive disease: A multicenter clinical trial of argatroban. J Thromb Thrombolysis 2:131-136, 1995.
10. Kario K, T Matsuo, H Kobayashi, M Matsuo, K Yamamoto, G Sakurai, M Baba: Rapid quantitative evaluation of plasma D-dimer levels in thrombotic states using an automated latex photometric immunoassay. Thromb Res 66:179-189, 1992.
11. Kario K, K Kodama, M Koide, T Matsuo: Thrombin inhibition in the acute phase of ischaemic stroke using argatroban. Blood Coag Fibrinolysis 6:423-427, 1995.