Expression cloning of a novel estrogenic mouse 17β-hydroxysteroid dehydrogenase/17-ketosteroid reductase (m17HSD7), previously described as a prolactin receptor-associated protein (PRAP) in rat

Molecular Endocrinology

Volumn 12, Issue 7, 1998, Pages 1048-1059

  Nokelainen, P ^a   Peltoketo, H ^a   Vihko, R ^a   Vihko, P ^a  

^a UNIVERSITY OF OULU   (Finland)

Author keywords

[No Author keywords available]

Indexed keywords

17 OXOSTEROID; ESTRADIOL; ESTRONE; PROLACTIN RECEPTOR; STEROID REDUCTASE; TESTOSTERONE 17BETA DEHYDROGENASE;

ANIMAL CELL; ARTICLE; CATALYSIS; CORPUS LUTEUM; ENZYME ACTIVITY; ENZYME ANALYSIS; ENZYME MECHANISM; ENZYME STRUCTURE; GENE EXPRESSION; GENETIC CODE; HORMONAL REGULATION; MOLECULAR CLONING; MOLECULAR WEIGHT; MOUSE; NONHUMAN; NUCLEOTIDE SEQUENCE; PREGNANCY; PRIORITY JOURNAL; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; TISSUE DISTRIBUTION;

ANIMALIA; EUKARYOTA; RODENTIA;

EID: 0032230308     PISSN: 08888809     EISSN: None     Source Type: Journal    
DOI: 10.1210/mend.12.7.0134     Document Type: Article

References (57)

1. Role of 17β-hydroxysteroid dehydrogenase type 1 in endocrine and intracrine estradiol biosynthesis
2. The key role of 17β-hydroxysteroid dehydrogenases in sex steroid biology
3. Mouse 17β-hydroxysteroid dehydrogenase type 2 mRNA is predominantly expressed in hepatocytes and in surface epithelial cells of the gastrointestinal and urinary tracts
4. Ontogeny of 17β-hydroxysteroid dehydrogenase type 2 mRNA expression in the developing mouse placenta and fetus
5. Complete amino acid sequence of human placental 17β-hydroxysteroid dehydrogenase deduced from cDNA
6. Characterization of cDNAs for human estradiol 17β-dehydrogenase and assignment of the gene to chromosome 17: Evidence of two mRNA species with distinct 5'-termini in human placenta
7. Expression cloning and characterization of human 17β-hydroxysteroid dehydrogenase type 2, a microsomal enzyme possessing 20α-hydroxysteroid dehydrogenase activity
8. Male pseudohermaphroditism caused by mutations of testicular 17β-hydroxysteroid dehydrogenase 3
9. Molecular cloning of a novel widely expressed human 80 kDa 17β-hydroxysteroid dehydrogenase IV
10. Molecular cloning of mouse 17β-hydroxysteroid dehydrogenase type 1 and characterization of enzyme activity
11. Cloning of mouse 17β-hydroxysteroid dehydrogenase type 2, and analysing expression of the mRNAs for types 1, 2, 3, 4 and 5 in mouse embryos and adult tissues
12. Sequence of mouse 17β-hydroxysteroid dehydrogenase type 3 cDNA and tissue distribution of the type 1 and type 3 isoform mRNAs
13. Molecular characterization of mouse 17β-hydroxysteroid dehydrogenase IV
14. Molecular cloning and characterization of mouse estradiol 17β-dehydrogenase (A-specific), a member of the aldoketoreductase family
15. Rat 17β-hydroxysteroid dehydrogenase type 1: Primary structure and regulation of enzyme expression in rat ovary by diethylstilbestrol and gonadotropins in vivo
16. Cloning of rat 17β-hydroxysteroid dehydrogenase type 2 and characterization of tissue distribution and catalytic activity of rat type 1 and type 2 enzymes
17. Peroxisomal multifunctional enzyme of β-oxidation metabolizing D-3-hydroxyacyl-CoA esters in rat liver: Molecular cloning, expression and characterization
18. Expression cloning and characterization of oxidative 17β- and 3α-hydroxysteroid dehydrogenases from rat and human prostate
19. Compartmentalization of type I 17β-hydroxysteroid oxidoreductase in the human ovary
20. Expression of 17β-hydroxysteroid dehydrogenase in human granulosa cells: Correlation with follicular size, cytochrome P450 aromatase activity and oestradiol production
21. Expression of 17β-hydroxysteroid dehydrogenase in the rat ovary during follicular development and luteinization induced with pregnant mare serum gonadotrophin and human chorionic gonadotrophin
22. Regulation of the gene for estrogenic 17-ketosteroid reductase lying on chromosome 17cen- > q25
23. Immunohistochemical localization of aromatase cytocrome P-450 and estradiol dehydrogenase in the syncytiotrophoblast of the human placenta
24. Immunohistochemical localization of 17β-hydroxysteroid dehydrogenase in the human endometrium during the menstrual cycle
25. Immunological analysis of 17β-hydroxysteroid dehydrogenase in benign and malignant human breast tissue
26. Immunohistochemical study of the human 17β-hydroxysteroid dehydrogenase and steroid receptors in endometrial adenocarcinoma
27. Differential estrogen substrate specificities for transiently expressed human placental 17β-hydroxysteroid dehydrogenase and an endogenous enzyme expressed in cultured COS-m6 cells
28. Origin of substrate specificity of human and rat 17β-hydroxysteroid dehydrogenase type 1, using chimeric enzymes and site-directed substitutions
29. Human 17β-hydroxysteroid dehydrogenase type 1 and type 2 isoenzymes have opposite activities in cultured cells and characteristic cell- and tissue-specific expression
30. 17β-hydroxysteroid dehydrogenase type 2: Chromosomal assignment and progestin regulation of gene expression in human endometrium
31. Characterization of 17β-hydroxysteroid dehydrogenase isoenzyme expression in benign and malignant human prostate
32. 27 bile acids di- and tri-hydroxycoprostanic acids are metabolized by separate multifunctional proteins
33. Rat 17β-hydroxysteroid dehydrogenase type IV is a novel peroxisome proliferator-inducible gene
34. Aromatase cytochrome P450, the enzyme responsible for estrogen biosynthesis
35. The corpus luteum of pregnancy
36. Expression of 17β-hydroxysteroid dehydrogenase type 1 and type 2, P450 aromatase, and 20α-hydroxysteroid dehydrogenase enzymes in immature, mature, and pregnant rats
37. In vivo and in vitro ovarian steroidogenesis in the pregnant rat
38. Cloning and characterization of an ovarian-specific protein that associates with the short form of the prolactin receptor
39. Prolactin regulation of β-casein gene expression and of a cytosolic 120-kd protein in a cloned mouse mammary epithelial cell line
40. Short-chain dehydrogenases/reductases (SDR)
41. Structure of human estrogenic 17β-hydroxysteroid dehydrogenase at 2.20 Å resolution
42. Hormonal and immunological characterization of the 32 kilodalton ovarian-specific protein
43. Distribution of 17β-hydroxysteroid dehydrogenase gene expression and activity in rat and human tissues
44. 17 β-hydroxysteroid oxidoreductase: A ubiquitous enzyme. Interconversion of estrone and estradiol-17β in BALB/c mouse tissues
45. Characterization of structural and functional properties of human 17β-hydroxysteroid dehydrogenase type 1 using recombinant enzymes and site-directed mutagenesis
46. Characteristics of human types 1, 2 and 3 17β-hydroxysteroid dehydrogenase activities: Oxidation/reduction and inhibition
47. PRAP, a prolactin receptor associated protein: Its gene expression and regulation in the corpus luteum
48. Hormonal regulation, tissue distribution, and content of aromatase cytochrome P450 messenger ribonucleic acid and enzyme in rat ovarian follicles and corpora lutea: Relationship to estradiol biosynthesis
49. The different forms of the prolactin receptor in the rat corpus luteum: Developmental expression and hormonal regulation in pregnancy
50. Prolactin induces phosphorylation of Tyr694 of Stat 5 (MGF), a prerequisite for DNA binding and induction of transcription
51. Differential signal transduction of the short, Nb2, and long prolactin receptors
52. Characterization of estrogen-dependent growth of cultured MCF-7 human breast-cancer cells expressing 17β-hydroxysteroid dehydrogenase type 1
53. Formation and metabolism of progesterone by the mouse placenta in vitro
54. Placental 17β-hydroxysteroid oxidoreductase, lactate dehydrogenase and malate dehydrogenase during the latter half of pregnancy in the mouse
55. Preparation and analysis of RNA from eukaryotic cells
56. Extraction, purification, and analysis of messenger RNA from eukaryotic cells
57. Glyceral-dehyde-3-phosphate dehydrogenase mRNA is a major interleukin 2-induced transcript in a cloned T-helper lymphocyte