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Volumn 136, Issue 1, 1998, Pages 47-56

Growth factors and phorbol-12-myristate-13-acetate modulate the follicle-stimulating hormone- and cyclic adenosine-3',5'-monophosphate-dependent regulation of 17β-hydroxysteroid dehydrogenase type 1 expression in rat granulosa cells

Author keywords

17 hydroxysteroid dehydrogenase type 1; cAMP; FSH; Granulosa cells (rat); Growth factors; Protein kinase C

Indexed keywords

8 BROMO CYCLIC AMP; ADENOSINE 3' PHOSPHATE; CYCLIC AMP; CYCLIC AMP DEPENDENT PROTEIN KINASE; EPIDERMAL GROWTH FACTOR; FOLLITROPIN; GROWTH FACTOR; PHORBOL 13 ACETATE 12 MYRISTATE; PROTEIN KINASE C; TESTOSTERONE 17BETA DEHYDROGENASE; TRANSFORMING GROWTH FACTOR ALPHA; TRANSFORMING GROWTH FACTOR BETA1;

EID: 0344352502     PISSN: 03037207     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0303-7207(97)00213-X     Document Type: Article
Times cited : (13)

References (48)
  • 1
    • 0028847134 scopus 로고
    • Molecular cloning of a novel widely expressed human 80 kDa 17β-hydroxysteroid dehydrogenase IV
    • Adamski J., Normand T., Leenders F. et al. Molecular cloning of a novel widely expressed human 80 kDa 17β-hydroxysteroid dehydrogenase IV. Biochem. J. 311:1995;437-443.
    • (1995) Biochem. J. , vol.311 , pp. 437-443
    • Adamski, J.1    Normand, T.2    Leenders, F.3
  • 2
    • 0022971816 scopus 로고
    • Antagonistic interactions of transformic growth factors in the regulation of granulosa cell differentiation
    • Adashi E.Y., Resnick C.E. Antagonistic interactions of transformic growth factors in the regulation of granulosa cell differentiation. Endocrinology. 119:1986;1879-1881.
    • (1986) Endocrinology , vol.119 , pp. 1879-1881
    • Adashi, E.Y.1    Resnick, C.E.2
  • 3
    • 0022401630 scopus 로고
    • Somatomedin-C-mediated potentiation of follicle-stimulating hormone-induced aromatase activity of cultured rat granulosa cells
    • Adashi E.Y., Resnick C.E., Brodie A.M., Svoboda M.E., van Wyk J.J. Somatomedin-C-mediated potentiation of follicle-stimulating hormone-induced aromatase activity of cultured rat granulosa cells. Endocrinology. 117:1985;2313-2320.
    • (1985) Endocrinology , vol.117 , pp. 2313-2320
    • Adashi, E.Y.1    Resnick, C.E.2    Brodie, A.M.3    Svoboda, M.E.4    Van Wyk, J.J.5
  • 4
    • 0023112725 scopus 로고
    • Transforming growth factor-α attenuates the acquisition of aromatase activity by cultured rat granulosa cells
    • Adashi E.Y., Resnick C.E., Twardzik D.R. Transforming growth factor-α attenuates the acquisition of aromatase activity by cultured rat granulosa cells. J. Cell Biochem. 33:1987;1-13.
    • (1987) J. Cell Biochem. , vol.33 , pp. 1-13
    • Adashi, E.Y.1    Resnick, C.E.2    Twardzik, D.R.3
  • 5
    • 0023846190 scopus 로고
    • Basic fibroblast growth factor as a regulator of ovarian granulosa cell differentiation: A novel non-mitogenic role
    • Adashi E.Y., Resnick C.E., Croft C.S., May J.V., Gospodarowicz D. Basic fibroblast growth factor as a regulator of ovarian granulosa cell differentiation: a novel non-mitogenic role. Mol. Cell. Endocrinol. 55:1988;7-14.
    • (1988) Mol. Cell. Endocrinol. , vol.55 , pp. 7-14
    • Adashi, E.Y.1    Resnick, C.E.2    Croft, C.S.3    May, J.V.4    Gospodarowicz, D.5
  • 7
    • 85047680034 scopus 로고    scopus 로고
    • Expression of 17β-hydroxysteroid dehydrogenase type 1 and type 2, P450 aromatase and 20α-hydroxysteroid dehydrogenase enzymes in immature, mature and pregnant rats
    • Akinola L.A., Poutanen M., Vihko R., Vihko P. Expression of 17β-hydroxysteroid dehydrogenase type 1 and type 2, P450 aromatase and 20α-hydroxysteroid dehydrogenase enzymes in immature, mature and pregnant rats. Endocrinology. 138:1997;2886-2892.
    • (1997) Endocrinology , vol.138 , pp. 2886-2892
    • Akinola, L.A.1    Poutanen, M.2    Vihko, R.3    Vihko, P.4
  • 8
    • 0024992730 scopus 로고
    • Epidermal growth factor influences growth and differentiation of rat granulosa cells
    • Bendell J.J., Dorrington J.H. Epidermal growth factor influences growth and differentiation of rat granulosa cells. Endocrinology. 127:1990;533-540.
    • (1990) Endocrinology , vol.127 , pp. 533-540
    • Bendell, J.J.1    Dorrington, J.H.2
  • 9
    • 0031040074 scopus 로고    scopus 로고
    • The effect of cyclic adenosine monophosphate on the mitogen-activated protein kinase pathway depends on both the cell type and the type of tyrosine kinase-receptor
    • Calleja V., Enriquez Pr., Filloux C., Peraldi P., Baron V., van Obberghen E. The effect of cyclic adenosine monophosphate on the mitogen-activated protein kinase pathway depends on both the cell type and the type of tyrosine kinase-receptor. Endocrinology. 138:1997;1111-1120.
    • (1997) Endocrinology , vol.138 , pp. 1111-1120
    • Calleja, V.1    Enriquez, Pr.2    Filloux, C.3    Peraldi, P.4    Baron, V.5    Van Obberghen, E.6
  • 10
    • 0027285388 scopus 로고
    • Interactions between FSH, estradiol-17β and transforming growth factor-β regulate growth and differentiation in the rat gonad
    • Dorrington J.H., Bendell J.J., Khan S.A. Interactions between FSH, estradiol-17β and transforming growth factor-β regulate growth and differentiation in the rat gonad. J. Steroid Biochem. Mol. Biol. 44:1993;441-447.
    • (1993) J. Steroid Biochem. Mol. Biol. , vol.44 , pp. 441-447
    • Dorrington, J.H.1    Bendell, J.J.2    Khan, S.A.3
  • 11
    • 0026093596 scopus 로고
    • Regulation of cytochrome P450 aromatase messenger ribonucleic acid and activity by steroids and gonadotropins in rat granulosa cells
    • Fitzpatrick S., Richards J. Regulation of cytochrome P450 aromatase messenger ribonucleic acid and activity by steroids and gonadotropins in rat granulosa cells. Endocrinology. 129:1991;1452-1462.
    • (1991) Endocrinology , vol.129 , pp. 1452-1462
    • Fitzpatrick, S.1    Richards, J.2
  • 12
    • 0027930787 scopus 로고
    • Male pseudohermaphroditism caused by mutations of testicular 17β-hydroxysteroid dehydrogenase 3
    • Geissler W.M., Davis D.L., Wu L. et al. Male pseudohermaphroditism caused by mutations of testicular 17β-hydroxysteroid dehydrogenase 3. Nat. Genet. 7:1994;34-39.
    • (1994) Nat. Genet. , vol.7 , pp. 34-39
    • Geissler, W.M.1    Davis, D.L.2    Wu, L.3
  • 13
    • 0028023426 scopus 로고
    • Expression of 17β-hydroxysteroid dehydrogenase in human granulosa cells: Correlation with follicular size, cytochrome P450 aromatase activity and oestradiol production
    • Ghersevich S.A., Poutanen M.H., Martikainen H.K., Vihko R. Expression of 17β-hydroxysteroid dehydrogenase in human granulosa cells: correlation with follicular size, cytochrome P450 aromatase activity and oestradiol production. J. Endocrinol. 143:1994a;139-150.
    • (1994) J. Endocrinol. , vol.143 , pp. 139-150
    • Ghersevich, S.A.1    Poutanen, M.H.2    Martikainen, H.K.3    Vihko, R.4
  • 14
    • 0028169544 scopus 로고
    • Rat 17β-hydroxysteroid dehydrogenase type 1: Primary structure and regulation of enzyme expression in rat ovary by diethylstilbestrol and gonadotropins in vivo
    • Ghersevich S., Nokelainen P., Poutanen M., Orava M., Autio-Harmainen H., Rajaniemi H., Vihko R. Rat 17β-hydroxysteroid dehydrogenase type 1: Primary structure and regulation of enzyme expression in rat ovary by diethylstilbestrol and gonadotropins in vivo. Endocrinology. 135:1994b;1477-1487.
    • (1994) Endocrinology , vol.135 , pp. 1477-1487
    • Ghersevich, S.1    Nokelainen, P.2    Poutanen, M.3    Orava, M.4    Autio-Harmainen, H.5    Rajaniemi, H.6    Vihko, R.7
  • 15
    • 0028178367 scopus 로고
    • Expression of 17β-hydroxysteroid dehydrogenase in the rat ovary during follicular development and luteinization induced with pregnant mare serum gonadotrophin and human chorionic gonadotrophin
    • Ghersevich S., Poutanen M., Rajaniemi H., Vihko R. Expression of 17β-hydroxysteroid dehydrogenase in the rat ovary during follicular development and luteinization induced with pregnant mare serum gonadotrophin and human chorionic gonadotrophin. J. Endocrinol. 140:1994c;409-417.
    • (1994) J. Endocrinol. , vol.140 , pp. 409-417
    • Ghersevich, S.1    Poutanen, M.2    Rajaniemi, H.3    Vihko, R.4
  • 16
    • 0028061883 scopus 로고
    • Hormonal regulation of rat 17β-hydroxysteroid dehydrogenase type 1 in cultured rat granulosa cells: Effects of recombinant follicle stimulating hormone, estrogens, androgens, and epidermal growth factor
    • Ghersevich S., Poutanen M., Tapanainen J., Vihko R. Hormonal regulation of rat 17β-hydroxysteroid dehydrogenase type 1 in cultured rat granulosa cells: effects of recombinant follicle stimulating hormone, estrogens, androgens, and epidermal growth factor. Endocrinology. 135:1994d;1963-1971.
    • (1994) Endocrinology , vol.135 , pp. 1963-1971
    • Ghersevich, S.1    Poutanen, M.2    Tapanainen, J.3    Vihko, R.4
  • 17
    • 0027196379 scopus 로고
    • The potential roles of intraovarian peptides in normal and abnormal mechanisms of reproductive physiology
    • Giudice L.C., Chandrasekher Y.A., Cataldo N.A. The potential roles of intraovarian peptides in normal and abnormal mechanisms of reproductive physiology. Curr. Opin. Obstet. Gynecol. 5:1993;350-359.
    • (1993) Curr. Opin. Obstet. Gynecol. , vol.5 , pp. 350-359
    • Giudice, L.C.1    Chandrasekher, Y.A.2    Cataldo, N.A.3
  • 18
    • 0029054116 scopus 로고
    • Effect of protein kinase C modulation on gonadotrophin-induced granulosa cell steroidogenesis
    • He H., Herington A.C., Roupas P. Effect of protein kinase C modulation on gonadotrophin-induced granulosa cell steroidogenesis. Reprod. Fertil. Dev. 7:1995;83-95.
    • (1995) Reprod. Fertil. Dev. , vol.7 , pp. 83-95
    • He, H.1    Herington, A.C.2    Roupas, P.3
  • 19
    • 0019824783 scopus 로고
    • Inhibition of ovarian and testicular steroidogenesis by epidermal growth factor
    • Hsueh A.J.W., Welsh T.H., Jones P.B.C. Inhibition of ovarian and testicular steroidogenesis by epidermal growth factor. Endocrinology. 108:1981;2002-2004.
    • (1981) Endocrinology , vol.108 , pp. 2002-2004
    • Hsueh, A.J.W.1    Welsh, T.H.2    Jones, P.B.C.3
  • 20
    • 0024588219 scopus 로고
    • Steroidogenesis of porcine granulosa cells from small and medium-sized follicles: Effects of follicle stimulating hormone, forskoline, and adenosine 3′,5′-cyclic monophosphate versus phorbol ester
    • Hylka V.W., Kaki M.K., DiZerega G.S. Steroidogenesis of porcine granulosa cells from small and medium-sized follicles: effects of follicle stimulating hormone, forskoline, and adenosine 3′,5′-cyclic monophosphate versus phorbol ester. Endocrinology. 124:1989;1204-1209.
    • (1989) Endocrinology , vol.124 , pp. 1204-1209
    • Hylka, V.W.1    Kaki, M.K.2    Dizerega, G.S.3
  • 21
    • 0022826745 scopus 로고
    • The neural type II regulatory subunit of cAMP-dependent protein kinase is present and regulated by hormones in the rat ovaries
    • Jahnsen T., Hedin L., Lohmann S.M., Walter U., Richards J.S. The neural type II regulatory subunit of cAMP-dependent protein kinase is present and regulated by hormones in the rat ovaries. J. Biol. Chem. 261:1986;6637-6639.
    • (1986) J. Biol. Chem. , vol.261 , pp. 6637-6639
    • Jahnsen, T.1    Hedin, L.2    Lohmann, S.M.3    Walter, U.4    Richards, J.S.5
  • 22
    • 33846403055 scopus 로고
    • Purification of 17β-hydroxysteroid dehydrogenase of human placenta and studies on its transhydrogenase function
    • Jarabak J., Adams J.A., Williams-Ashman H.G., Talalay P. Purification of 17β-hydroxysteroid dehydrogenase of human placenta and studies on its transhydrogenase function. J. Biol. Chem. 137:1962;345-357.
    • (1962) J. Biol. Chem. , vol.137 , pp. 345-357
    • Jarabak, J.1    Adams, J.A.2    Williams-Ashman, H.G.3    Talalay, P.4
  • 23
    • 0022653106 scopus 로고
    • Possible involvement of protein kinase C and calcium ion in growth factor-induced expression of c-myc oncogene in Swiss 3T3 fibroblasts
    • Kaibuchi K., Tsuda T., Kikuchi A., Tanimoto T., Yamashita T., Takai Y. Possible involvement of protein kinase C and calcium ion in growth factor-induced expression of c-myc oncogene in Swiss 3T3 fibroblasts. J. Biol. Chem. 261:1986;1187-1192.
    • (1986) J. Biol. Chem. , vol.261 , pp. 1187-1192
    • Kaibuchi, K.1    Tsuda, T.2    Kikuchi, A.3    Tanimoto, T.4    Yamashita, T.5    Takai, Y.6
  • 24
    • 0027326410 scopus 로고
    • Protein kinase Cα activates RAF-1 by direct phosphorylation
    • Kolch W., Heldecker G., Kochs G. et al. Protein kinase Cα activates RAF-1 by direct phosphorylation. Nature. 364:1993;249-252.
    • (1993) Nature , vol.364 , pp. 249-252
    • Kolch, W.1    Heldecker, G.2    Kochs, G.3
  • 25
    • 0024408851 scopus 로고
    • Detection of acidic fibroblast growth factor mRNA in the rat ovary using reverse transcription-polymerase chain reaction amplification
    • Koos R.D., Seidel R.H. Detection of acidic fibroblast growth factor mRNA in the rat ovary using reverse transcription-polymerase chain reaction amplification. Biochem. Biophys. Res. Commun. 165:1989;82-88.
    • (1989) Biochem. Biophys. Res. Commun. , vol.165 , pp. 82-88
    • Koos, R.D.1    Seidel, R.H.2
  • 26
    • 0023264942 scopus 로고
    • Ovarian transforming growth factor-α gene expression: Immunohistochemical localization to the theca interstitial cells
    • Kudlow J.E., Kobrin M.S., Purchio A.F., Twardzik D.K., Hernandez E.R., Asa S.L., Adashi E.Y. Ovarian transforming growth factor-α gene expression: immunohistochemical localization to the theca interstitial cells. Endocrinology. 121:1987;1577-1579.
    • (1987) Endocrinology , vol.121 , pp. 1577-1579
    • Kudlow, J.E.1    Kobrin, M.S.2    Purchio, A.F.3    Twardzik, D.K.4    Hernandez, E.R.5    Asa, S.L.6    Adashi, E.Y.7
  • 27
    • 0029742706 scopus 로고    scopus 로고
    • Transforming growth factor-β: A general review
    • Lawrance D.A. Transforming growth factor-β: a general review. Eur. Cytokine Netw. 7:1996;363-374.
    • (1996) Eur. Cytokine Netw. , vol.7 , pp. 363-374
    • Lawrance, D.A.1
  • 28
    • 0026675659 scopus 로고
    • Intracellular signaling in the gonads
    • Leung P.C.K., Steele G.L. Intracellular signaling in the gonads. Endocr. Rev. 13:1992;476-498.
    • (1992) Endocr. Rev. , vol.13 , pp. 476-498
    • Leung, P.C.K.1    Steele, G.L.2
  • 29
    • 0026587358 scopus 로고
    • Distribution of 17β-hydroxysteroid dehydrogenase gene expression and activity in rat and human tissues
    • Martel C., Rheaume E., Takahashi M., Trudel C. et al. Distribution of 17β-hydroxysteroid dehydrogenase gene expression and activity in rat and human tissues. J. Steroid Biochem. Mol. Biol. 41:1992;597-603.
    • (1992) J. Steroid Biochem. Mol. Biol. , vol.41 , pp. 597-603
    • Martel, C.1    Rheaume, E.2    Takahashi, M.3    Trudel, C.4
  • 30
    • 0029904671 scopus 로고    scopus 로고
    • Serine/threonine kinase receptors: Mediators of transforming growth factor beta family signals
    • Massague J., Weis-Garcia F. Serine/threonine kinase receptors: mediators of transforming growth factor beta family signals. Cancer Surv. 27:1996;41-65.
    • (1996) Cancer Surv. , vol.27 , pp. 41-65
    • Massague, J.1    Weis-Garcia, F.2
  • 31
    • 0029670229 scopus 로고    scopus 로고
    • Human 17β-hydroxysteroid dehydrogenase type 1 and type 2 isoenzymes have opposite activities in cultured cells and characteristic cell and tissue specific expression
    • Miettinen M.M., Mustonen M.V.J., Poutanen M.H., Isomaa V.V., Vihko R.K. Human 17β-hydroxysteroid dehydrogenase type 1 and type 2 isoenzymes have opposite activities in cultured cells and characteristic cell and tissue specific expression. Biochem. J. 314:1996;839-845.
    • (1996) Biochem. J. , vol.314 , pp. 839-845
    • Miettinen, M.M.1    Mustonen, M.V.J.2    Poutanen, M.H.3    Isomaa, V.V.4    Vihko, R.K.5
  • 32
    • 0024306944 scopus 로고
    • Activity of 17β-hydroxysteroid oxidoreductase in tissues of the human fetus
    • Milewicz L., McDonald P.C., Carr B.R. Activity of 17β-hydroxysteroid oxidoreductase in tissues of the human fetus. J. Endocrinol. 123:1989;509-518.
    • (1989) J. Endocrinol. , vol.123 , pp. 509-518
    • Milewicz, L.1    McDonald, P.C.2    Carr, B.R.3
  • 33
    • 0025215193 scopus 로고
    • Rat granulosa cells express transforming growth factor-β type 2 messenger ribonucleic acid which is regulatable by follicle-stimulating hormone in vitro
    • Mulheron G.W., Schomber D.W. Rat granulosa cells express transforming growth factor-β type 2 messenger ribonucleic acid which is regulatable by follicle-stimulating hormone in vitro. Endocrinology. 126:1990;1777-1779.
    • (1990) Endocrinology , vol.126 , pp. 1777-1779
    • Mulheron, G.W.1    Schomber, D.W.2
  • 36
    • 0028971813 scopus 로고
    • Phosphoinositide-specific phospholipase C and mitogenic signaling
    • Noh D.Y., Shin S.H., Rhee S.G. Phosphoinositide-specific phospholipase C and mitogenic signaling. Biochim. Biophys. Acta. 1242:1995;99-114.
    • (1995) Biochim. Biophys. Acta , vol.1242 , pp. 99-114
    • Noh, D.Y.1    Shin, S.H.2    Rhee, S.G.3
  • 37
    • 0026755613 scopus 로고
    • Regulation of cyclic adenosine 3′,5′-monophosphate-dependent protein kinase activity and regulatory subunit RIIβ content by basic fibroblast growth factor (bFGF) during granulosa cell differentiation: Possible implication of protein kinase C in bFGF action
    • Oury F., Faucher C., Rives I., Bensaid M., Bouch G., Darbon J.M. Regulation of cyclic adenosine 3′,5′-monophosphate-dependent protein kinase activity and regulatory subunit RIIβ content by basic fibroblast growth factor (bFGF) during granulosa cell differentiation: possible implication of protein kinase C in bFGF action. Biol. Reprod. 47:1992;202-212.
    • (1992) Biol. Reprod. , vol.47 , pp. 202-212
    • Oury, F.1    Faucher, C.2    Rives, I.3    Bensaid, M.4    Bouch, G.5    Darbon, J.M.6
  • 38
    • 0026609107 scopus 로고
    • Regulation of aromatase activity in FSH-primed rat granulosa cells in vitro by follicle-stimulating hormone and various amounts of human chorionic gonadotrophin
    • Overes H.W.T., de Leeuw R., Kloosterboer H.J. Regulation of aromatase activity in FSH-primed rat granulosa cells in vitro by follicle-stimulating hormone and various amounts of human chorionic gonadotrophin. Hum. Reprod. 7:1992;191-196.
    • (1992) Hum. Reprod. , vol.7 , pp. 191-196
    • Overes, H.W.T.1    De Leeuw, R.2    Kloosterboer, H.J.3
  • 39
    • 0027485031 scopus 로고
    • Increasing cAMP attenuates activation of mitogen-activated protein kinase
    • Sevetson B.R., Kong X., Lawrance Jr J.C. Increasing cAMP attenuates activation of mitogen-activated protein kinase. Proc. Natl. Acad. Sci. USA. 90:1993;10305-10309.
    • (1993) Proc. Natl. Acad. Sci. USA , vol.90 , pp. 10305-10309
    • Sevetson, B.R.1    Kong, X.2    Lawrance Jr, J.C.3
  • 40
    • 0022372665 scopus 로고
    • Inhibition of gonadotropin-induced granulosa cell differentiation by activation of protein kinase C
    • Shinohara O., Knecht M., Catt K.J. Inhibition of gonadotropin-induced granulosa cell differentiation by activation of protein kinase C. Proc. Natl. Acad. Sci. USA. 82:1985;8518-8522.
    • (1985) Proc. Natl. Acad. Sci. USA , vol.82 , pp. 8518-8522
    • Shinohara, O.1    Knecht, M.2    Catt, K.J.3
  • 41
    • 0020627040 scopus 로고
    • Rat ovarian epidermal growth factor receptors: Characterization and normal regulation
    • St-Arnaud R., Walker P., Kelly P.A., Labrie F. Rat ovarian epidermal growth factor receptors: characterization and normal regulation. Mol. Cell. Endocrinol. 31:1983;43-52.
    • (1983) Mol. Cell. Endocrinol. , vol.31 , pp. 43-52
    • St-Arnaud, R.1    Walker, P.2    Kelly, P.A.3    Labrie, F.4
  • 42
    • 0024994255 scopus 로고
    • Establishment of highly steroidogenic granulosa cell lines by contrasfection with SV 40 and Ha-ras oncogene: Induction of steroidogenesis by cyclic adenosine 3′-5′-monophosphate and its suppression by phorbol ester
    • Suh B.S., Amsterdam A. Establishment of highly steroidogenic granulosa cell lines by contrasfection with SV 40 and Ha-ras oncogene: induction of steroidogenesis by cyclic adenosine 3′-5′-monophosphate and its suppression by phorbol ester. Endocrinology. 127:1990;2489-2500.
    • (1990) Endocrinology , vol.127 , pp. 2489-2500
    • Suh, B.S.1    Amsterdam, A.2
  • 44
    • 0023151695 scopus 로고
    • Epidermal growth factor (EGF) stimulates inositol triphosphate formation in cells which overexpress the EGF receptor
    • Wahl M.I., Sweatt J.D., Carpenter G. Epidermal growth factor (EGF) stimulates inositol triphosphate formation in cells which overexpress the EGF receptor. Biochem. Biophys. Res. Commun. 142:1987;688-695.
    • (1987) Biochem. Biophys. Res. Commun. , vol.142 , pp. 688-695
    • Wahl, M.I.1    Sweatt, J.D.2    Carpenter, G.3
  • 45
    • 0027225486 scopus 로고
    • Expression, cloning and characterization of human 17β-hydroxysteroid dehydrogenase type 2, a microsomal enzyme possessing 20α-hydroxysteroid dehydrogenase activity
    • Wu L., Einstein M., Geissler W.M., Chan H.K., Elliston K.O., Andersson S. Expression, cloning and characterization of human 17β-hydroxysteroid dehydrogenase type 2, a microsomal enzyme possessing 20α-hydroxysteroid dehydrogenase activity. J. Biol. Chem. 268:1993a;12964-12969.
    • (1993) J. Biol. Chem. , vol.268 , pp. 12964-12969
    • Wu, L.1    Einstein, M.2    Geissler, W.M.3    Chan, H.K.4    Elliston, K.O.5    Andersson, S.6
  • 46
    • 0027772672 scopus 로고
    • Inhibition of the EGF-activated MAP kinase signaling pathway by adenosine 3′,5′-monophosphate
    • Wu J., Dent P., Jelinek T., Wolfman A., Weber M.J., Sturgill T.W. Inhibition of the EGF-activated MAP kinase signaling pathway by adenosine 3′,5′-monophosphate. Science. 262:1993b;1065-1069.
    • (1993) Science , vol.262 , pp. 1065-1069
    • Wu, J.1    Dent, P.2    Jelinek, T.3    Wolfman, A.4    Weber, M.J.5    Sturgill, T.W.6
  • 47
    • 0029551805 scopus 로고
    • Identification of a member of the MAPKKK family as a potential mediator of TGF-β signal transduction
    • Yamaguchi K., Shirakabe K., Shibuya H. et al. Identification of a member of the MAPKKK family as a potential mediator of TGF-β signal transduction. Science. 270:1995;2008-2011.
    • (1995) Science , vol.270 , pp. 2008-2011
    • Yamaguchi, K.1    Shirakabe, K.2    Shibuya, H.3
  • 48
    • 0022548458 scopus 로고
    • Inhibin and beta type transforming growth factor (TGFβ) have opposite modulating effects on the follicle stimulating hormone (FSH)-induced aromatase activity of cultured rat granulosa cells
    • Ying S.Y., Becker A., Ling N., Ueno N., Guillemin R. Inhibin and beta type transforming growth factor (TGFβ) have opposite modulating effects on the follicle stimulating hormone (FSH)-induced aromatase activity of cultured rat granulosa cells. Biochem. Biophys. Res. Commun. 136:1986;969-975.
    • (1986) Biochem. Biophys. Res. Commun. , vol.136 , pp. 969-975
    • Ying, S.Y.1    Becker, A.2    Ling, N.3    Ueno, N.4    Guillemin, R.5


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