-
1
-
-
0017040058
-
Free-energy profile for the reaction catalyzed by triosephosphate isomerase
-
Albery, W. J., Knowles, J. R. 1976. Free-energy profile for the reaction catalyzed by triosephosphate isomerase. Biochemistry 15: 5627-5631.
-
(1976)
Biochemistry
, vol.15
, pp. 5627-5631
-
-
Albery, W.J.1
Knowles, J.R.2
-
2
-
-
0016810498
-
Structure of chicken muscle triose phosphate isomerase determined crystallographically at 2.5 Å resolution using amino acid sequence data
-
Banner, D. W., Bloomer, A. C., Petsko, G, A., Phillips, D. C., Pogson, C. I., Wilson, I. A., Corran, P. H., Furth, A. J., Milman, J. D., Offord, R. E., Priddle, J. D., Waley, S. G. 1975. Structure of chicken muscle triose phosphate isomerase determined crystallographically at 2.5 Å resolution using amino acid sequence data. Nature 255: 609-614.
-
(1975)
Nature
, vol.255
, pp. 609-614
-
-
Banner, D.W.1
Bloomer, A.C.2
Petsko, G.A.3
Phillips, D.C.4
Pogson, C.I.5
Wilson, I.A.6
Corran, P.H.7
Furth, A.J.8
Milman, J.D.9
Offord, R.E.10
Priddle, J.D.11
Waley, S.G.12
-
3
-
-
49549135300
-
Atomic coordinates for triose phosphate isomerase from chicken muscle
-
Banner, D. W., Bloomer, A. C., Petsko, G. A., Phillips, D. C., Wilson, I. A. 1976. Atomic coordinates for triose phosphate isomerase from chicken muscle. Biochem. Biophys. Res. Commun. 72: 146.
-
(1976)
Biochem. Biophys. Res. Commun.
, vol.72
, pp. 146
-
-
Banner, D.W.1
Bloomer, A.C.2
Petsko, G.A.3
Phillips, D.C.4
Wilson, I.A.5
-
4
-
-
0025152833
-
The multifunctional 6-methylsalicyclic acid synthase gene of Penicillium patulum. Its gene structure relative to that of other polyketide synthases
-
Beck, J., Ripka, S., Siegner, A., Schiltz, E., Schweizer, E. 1990. The multifunctional 6-methylsalicyclic acid synthase gene of Penicillium patulum. Its gene structure relative to that of other polyketide synthases. Eur. J. Biochem. 192: 487-498.
-
(1990)
Eur. J. Biochem.
, vol.192
, pp. 487-498
-
-
Beck, J.1
Ripka, S.2
Siegner, A.3
Schiltz, E.4
Schweizer, E.5
-
5
-
-
0029161160
-
Expression of a functional fungal polyketide synthase in the bacterium Streptomyces coelicolor A3(2)
-
Bedford, D. J., Schweizer, E., Hopwood, D. A., Khosla, C. 1995. Expression of a functional fungal polyketide synthase in the bacterium Streptomyces coelicolor A3(2). J. Bacteriol. 177: 4544-4548.
-
(1995)
J. Bacteriol.
, vol.177
, pp. 4544-4548
-
-
Bedford, D.J.1
Schweizer, E.2
Hopwood, D.A.3
Khosla, C.4
-
6
-
-
0024449599
-
Analysis of the nucleotide sequence of the Streptomyces glaucescens tcml genes provides key information about the enzymology of polyketide biosynthesis
-
Bibb, M. J., Biró, S., Motamedi, H., Collins, J. F., Hutchinson, C. R. 1989. Analysis of the nucleotide sequence of the Streptomyces glaucescens tcml genes provides key information about the enzymology of polyketide biosynthesis. EMBO J. 8: 2727-2736.
-
(1989)
EMBO J.
, vol.8
, pp. 2727-2736
-
-
Bibb, M.J.1
Biró, S.2
Motamedi, H.3
Collins, J.F.4
Hutchinson, C.R.5
-
7
-
-
0028351394
-
Cloning, sequencing and deduced functions of a cluster of Strepyomyces genes probably encoding biosynthesis of the polyketide antibiotic frenolicin
-
Bibb, M. J., Sherman, D. H., Omura, S., Hopwood, D. A. 1994. Cloning, sequencing and deduced functions of a cluster of Strepyomyces genes probably encoding biosynthesis of the polyketide antibiotic frenolicin. Gene 142: 31-39.
-
(1994)
Gene
, vol.142
, pp. 31-39
-
-
Bibb, M.J.1
Sherman, D.H.2
Omura, S.3
Hopwood, D.A.4
-
8
-
-
0028209385
-
Efficient sampling of protein sequence space for multiple mutants
-
Caren, R., Morkeberg, R., Khosla, C. 1994. Efficient sampling of protein sequence space for multiple mutants. Bio/Technology 12: 517-520.
-
(1994)
Bio/Technology
, vol.12
, pp. 517-520
-
-
Caren, R.1
Morkeberg, R.2
Khosla, C.3
-
9
-
-
0025081416
-
An unusually large multifunctional polypeptide in the erythromycin-producing polyketide synthase of Saccharopolyspora erythraea
-
Cortes, J., Haydock, S. F., Roberts, G. A., Bevitt, D. J., Leadlay, P. F. 1990. An unusually large multifunctional polypeptide in the erythromycin-producing polyketide synthase of Saccharopolyspora erythraea. Nature 348: 176-178.
-
(1990)
Nature
, vol.348
, pp. 176-178
-
-
Cortes, J.1
Haydock, S.F.2
Roberts, G.A.3
Bevitt, D.J.4
Leadlay, P.F.5
-
10
-
-
0026415106
-
Modular organization of genes required for complex polyketide biosynthesis
-
Donadio, S., Staver, M. J., McAlpine, J. B., Swanson, S. J., Katz, L. 1991. Modular organization of genes required for complex polyketide biosynthesis. Science 252: 675-679.
-
(1991)
Science
, vol.252
, pp. 675-679
-
-
Donadio, S.1
Staver, M.J.2
McAlpine, J.B.3
Swanson, S.J.4
Katz, L.5
-
11
-
-
0025284257
-
The evolution of a/b barrel enzymes
-
Farber, G. K., Petsko, G. A. 1990. The evolution of a/b barrel enzymes. Trends Biochem. Sci. 15: 228-234.
-
(1990)
Trends Biochem. Sci.
, vol.15
, pp. 228-234
-
-
Farber, G.K.1
Petsko, G.A.2
-
12
-
-
0026657813
-
Nucleotide sequence and deduced functions of a set of cotranscribed genes of Streptomyces coelicolor A3(2) including the polyketide synthase for the antibiotic actinorhodin
-
Fernández-Moreno, M. A., Martínez, E., Boto, L., Hopwood, D. A., Malpartida, F. 1992. Nucleotide sequence and deduced functions of a set of cotranscribed genes of Streptomyces coelicolor A3(2) including the polyketide synthase for the antibiotic actinorhodin. J. Biol. Chem. 267: 19278-19290.
-
(1992)
J. Biol. Chem.
, vol.267
, pp. 19278-19290
-
-
Fernández-Moreno, M.A.1
Martínez, E.2
Boto, L.3
Hopwood, D.A.4
Malpartida, F.5
-
13
-
-
0028242645
-
Engineered biosynthesis of novel polyketides: Dissection of the catalytic specificity of the act ketoreductase
-
Fu, H., Ebert-Khosla, S., Hopwood, D. A., Khosla, C. 1994a. Engineered biosynthesis of novel polyketides: dissection of the catalytic specificity of the act ketoreductase. J. Am. Chem. Soc. 116: 4166-4170.
-
(1994)
J. Am. Chem. Soc.
, vol.116
, pp. 4166-4170
-
-
Fu, H.1
Ebert-Khosla, S.2
Hopwood, D.A.3
Khosla, C.4
-
14
-
-
0028136803
-
Relaxed specificity of the oxytetracycline polyketide synthase for an acetate primer in the absence of a malonamyl primer
-
Fu, H., Ebert-Khosla, S., Hopwood, D. A., Khosla, C. 1994b. Relaxed specificity of the oxytetracycline polyketide synthase for an acetate primer in the absence of a malonamyl primer. J. Am. Chem. Soc. 116:6443-6444.
-
(1994)
J. Am. Chem. Soc.
, vol.116
, pp. 6443-6444
-
-
Fu, H.1
Ebert-Khosla, S.2
Hopwood, D.A.3
Khosla, C.4
-
15
-
-
0028674981
-
Engineered biosynthesis of novel polyketides: Evidence for temporal, but not regiospecific, control of cyclization of an aromatic polyketide precursor
-
Fu, H., Hopwood, D. A., Khosla, C. 1994c. Engineered biosynthesis of novel polyketides: evidence for temporal, but not regiospecific, control of cyclization of an aromatic polyketide precursor. Chem. Biol. 1: 205-210.
-
(1994)
Chem. Biol.
, vol.1
, pp. 205-210
-
-
Fu, H.1
Hopwood, D.A.2
Khosla, C.3
-
16
-
-
0027964653
-
Engineered biosynthesis of novel polyketides: Stereochemical course of two reactions catalyzed by a polyketide synthase
-
Fu, H., McDaniel, R., Hopwood, D. A., Khosla, C. 1994d. Engineered biosynthesis of novel polyketides: stereochemical course of two reactions catalyzed by a polyketide synthase. Biochemistry 33: 9321-9326.
-
(1994)
Biochemistry
, vol.33
, pp. 9321-9326
-
-
Fu, H.1
McDaniel, R.2
Hopwood, D.A.3
Khosla, C.4
-
17
-
-
0024297340
-
Three-dimensional structure of the tryptophan synthase a2b2 multienzyme complex from Salmonella typhimurium
-
Hyde, C. C., Ahmed, S. A., Padlan, E. A., Miles, E. W., Davies, D. R. 1988. Three-dimensional structure of the tryptophan synthase a2b2 multienzyme complex from Salmonella typhimurium. J. Biol. Chem. 263: 17857-17871.
-
(1988)
J. Biol. Chem.
, vol.263
, pp. 17857-17871
-
-
Hyde, C.C.1
Ahmed, S.A.2
Padlan, E.A.3
Miles, E.W.4
Davies, D.R.5
-
18
-
-
0027932534
-
Engineered biosynthesis of a complete macrolactone in a heterologous host
-
Kao, C. M., Katz, L., Khosla, C. 1994. Engineered biosynthesis of a complete macrolactone in a heterologous host. Science 265: 509-512.
-
(1994)
Science
, vol.265
, pp. 509-512
-
-
Kao, C.M.1
Katz, L.2
Khosla, C.3
-
19
-
-
0028556312
-
Engineered biosynthesis of a triketide lactone from an incomplete modular polyketide synthase
-
Kao, C. M., Luo, G., Katz, L., Cane, D. E., Khosla, C. 1994. Engineered biosynthesis of a triketide lactone from an incomplete modular polyketide synthase. J. Am. Chem. Soc. 116: 11612-11613.
-
(1994)
J. Am. Chem. Soc.
, vol.116
, pp. 11612-11613
-
-
Kao, C.M.1
Luo, G.2
Katz, L.3
Cane, D.E.4
Khosla, C.5
-
20
-
-
0028857296
-
Manipulation of lactone ring size of a macrolide aglycone by directed mutagenesis of a modular polyketide synthase
-
in press
-
Kao, C. M., Luo, G., Katz, L., Cane, D. E., Khosla, C. 1995. Manipulation of lactone ring size of a macrolide aglycone by directed mutagenesis of a modular polyketide synthase. J. Am. Chem. Soc. 117 (in press).
-
(1995)
J. Am. Chem. Soc.
, vol.117
-
-
Kao, C.M.1
Luo, G.2
Katz, L.3
Cane, D.E.4
Khosla, C.5
-
21
-
-
0027908014
-
Engineered biosynthesis of novel polyketides
-
McDaniel, R., Ebert-Khosla, S., Hopwood, D. A., Khosla, C. 1993a. Engineered biosynthesis of novel polyketides. Science 262: 1546-1550.
-
(1993)
Science
, vol.262
, pp. 1546-1550
-
-
McDaniel, R.1
Ebert-Khosla, S.2
Hopwood, D.A.3
Khosla, C.4
-
22
-
-
0027746346
-
Engineered biosynthesis of novel polyketides: Manipulation and analysis of an aromatic polyketide synthase with unproven catalytic specificities
-
McDaniel, R., Ebert-Khosla, S., Hopwood, D. A., Khosla, C. 1993b. Engineered biosynthesis of novel polyketides: manipulation and analysis of an aromatic polyketide synthase with unproven catalytic specificities. J. Am. Chem. Soc. 115: 11671-11675.
-
(1993)
J. Am. Chem. Soc.
, vol.115
, pp. 11671-11675
-
-
McDaniel, R.1
Ebert-Khosla, S.2
Hopwood, D.A.3
Khosla, C.4
-
23
-
-
0028575694
-
Engineered biosynthesis of novel polyketides: ArtVII and actIV genes encode aromatase and cyclase enzymes, respectively
-
McDaniel, R., Ebert-Khosla, S., Hopwood, D. A., Khosla, C. 1994a. Engineered biosynthesis of novel polyketides: artVII and actIV genes encode aromatase and cyclase enzymes, respectively. J. Am. Chem. Soc. 116: 10855-10859.
-
(1994)
J. Am. Chem. Soc.
, vol.116
, pp. 10855-10859
-
-
McDaniel, R.1
Ebert-Khosla, S.2
Hopwood, D.A.3
Khosla, C.4
-
24
-
-
0027970295
-
Engineered biosynthesis of novel polyketides: Influence of a downstream enzyme on the catalytic specificity of a minimal aromatic polyketide synthase
-
McDaniel, R., Ebert-Khosla, S., Fu, H., Hopwood, D. A., Khosla, C. 1994b. Engineered biosynthesis of novel polyketides: influence of a downstream enzyme on the catalytic specificity of a minimal aromatic polyketide synthase. Proc. Natl. Acad. Sci. USA 91: 11542-11546.
-
(1994)
Proc. Natl. Acad. Sci. USA
, vol.91
, pp. 11542-11546
-
-
McDaniel, R.1
Ebert-Khosla, S.2
Fu, H.3
Hopwood, D.A.4
Khosla, C.5
-
25
-
-
0029064652
-
Rational design of aromatic polyketide natural products by modular assembly of enzymatic subunits
-
McDaniel, R., Ebert-Khosla, S., Hopwood, D. A., Khosla, C. 1995. Rational design of aromatic polyketide natural products by modular assembly of enzymatic subunits. Nature 375: 549-554.
-
(1995)
Nature
, vol.375
, pp. 549-554
-
-
McDaniel, R.1
Ebert-Khosla, S.2
Hopwood, D.A.3
Khosla, C.4
-
26
-
-
0029054128
-
Engineered biosynthesis of novel polyketides: Analysis of tcmN function in tetracenomycin biosynthesis
-
McDaniel, R., Hutchinson, C. R., Khosla, C. 1995. Engineered biosynthesis of novel polyketides: analysis of tcmN function in tetracenomycin biosynthesis. J. Am. Chem. Soc. 117: 6805-6810.
-
(1995)
J. Am. Chem. Soc.
, vol.117
, pp. 6805-6810
-
-
McDaniel, R.1
Hutchinson, C.R.2
Khosla, C.3
-
27
-
-
0024594385
-
The a subunit of tryptophan synthase
-
Nagata, S., Hyde, C. C., Miles, E. W. 1989. The a subunit of tryptophan synthase. J. Biol. Chem. 264: 6288-6296.
-
(1989)
J. Biol. Chem.
, vol.264
, pp. 6288-6296
-
-
Nagata, S.1
Hyde, C.C.2
Miles, E.W.3
-
28
-
-
0010352392
-
Nucleotide sequences of trpA of Salmonella typhimurium and Escherichia coli: An evolutionary comparison
-
Nichols, B. P., Yanofsky, C. 1979. Nucleotide sequences of trpA of Salmonella typhimurium and Escherichia coli: an evolutionary comparison. Proc. Natl. Acad. Sci. USA 76: 5244-5248.
-
(1979)
Proc. Natl. Acad. Sci. USA
, vol.76
, pp. 5244-5248
-
-
Nichols, B.P.1
Yanofsky, C.2
-
30
-
-
7844236404
-
A general cleavage reaction of 3-substituted indoles
-
Powers, J. C. 1965. A general cleavage reaction of 3-substituted indoles. Tetrahed. Lett. 11: 655-658.
-
(1965)
Tetrahed. Lett.
, vol.11
, pp. 655-658
-
-
Powers, J.C.1
-
31
-
-
0026345258
-
Random mutagenesis of protein sequences using oligonucleotide cassettes
-
Reidhaar-Olson, J. F., Bowie, J. U., Breyer, R. M., Hu, J. C., Knight, K. L., Lim, W. A., Mossing, M. C., Parsell, D. A., Shoemaker, K. R., Sauer, R. T. 1991. Random mutagenesis of protein sequences using oligonucleotide cassettes. Meth. Enzymol. 208: 564-586.
-
(1991)
Meth. Enzymol.
, vol.208
, pp. 564-586
-
-
Reidhaar-Olson, J.F.1
Bowie, J.U.2
Breyer, R.M.3
Hu, J.C.4
Knight, K.L.5
Lim, W.A.6
Mossing, M.C.7
Parsell, D.A.8
Shoemaker, K.R.9
Sauer, R.T.10
-
33
-
-
0026588622
-
Nucleotide sequence of the tcmII-tcmIV region of the tetracenomycin C biosynthetic gene cluster of Streptomyces glaucescens and evidence that the tcmN gene encodes a multifunctional cyclasedehydratase-O-methyl transferase
-
Summers, R. G., Wendt-Pienkowski, E., Motamedi, H., Hutchinson, C. R. 1992. Nucleotide sequence of the tcmII-tcmIV region of the tetracenomycin C biosynthetic gene cluster of Streptomyces glaucescens and evidence that the tcmN gene encodes a multifunctional cyclasedehydratase-O-methyl transferase. J. Bacteriol. 174: 1810-1820.
-
(1992)
J. Bacteriol.
, vol.174
, pp. 1810-1820
-
-
Summers, R.G.1
Wendt-Pienkowski, E.2
Motamedi, H.3
Hutchinson, C.R.4
-
34
-
-
0026014458
-
Structural conservation in parallel b/a-barrel enzymes that catalyze three sequential reactions in the pathway of tryptophan biosynthesis
-
Wilmanns, M., Hyde, C. C., Davies, D. R., Kirshner, K. Jansonius, J. N. 1991. Structural conservation in parallel b/a-barrel enzymes that catalyze three sequential reactions in the pathway of tryptophan biosynthesis. Biochemistry 30: 9161-9169.
-
(1991)
Biochemistry
, vol.30
, pp. 9161-9169
-
-
Wilmanns, M.1
Hyde, C.C.2
Davies, D.R.3
Kirshner, K.4
Jansonius, J.N.5
-
35
-
-
0026584311
-
Three-dimensional structure of the bifunctional enzyme phosphoribosylanthraniliate isomerase: Indoleglycerolphosphate synthase from Escherichia coli refined at 2.0 Å resolution
-
Wilmanns, M., Priestle, J. P., Niermann, T., Jansonius, J. N. 1992. Three-dimensional structure of the bifunctional enzyme phosphoribosylanthraniliate isomerase: indoleglycerolphosphate synthase from Escherichia coli refined at 2.0 Å resolution. J. Mol. Biol. 223: 477-507.
-
(1992)
J. Mol. Biol.
, vol.223
, pp. 477-507
-
-
Wilmanns, M.1
Priestle, J.P.2
Niermann, T.3
Jansonius, J.N.4
-
36
-
-
0027516733
-
Partial revertants of tryptophan synthetase a chain active site mutant Asp60→Asn
-
Yanofsky, C., Yee, M. C., Horn, V. 1993. Partial revertants of tryptophan synthetase a chain active site mutant Asp60→Asn. J. Biol. Chem. 268: 8213-8220.
-
(1993)
J. Biol. Chem.
, vol.268
, pp. 8213-8220
-
-
Yanofsky, C.1
Yee, M.C.2
Horn, V.3
|