A pathogenetic role for the thymoma in myasthenia gravis. Autosensitization of IL-4-producing T cell clones recognizing extracellular acetylcholine receptor epitopes presented by minority class II isotypes

Journal of Clinical Investigation

Volumn 101, Issue 10, 1998, Pages 2268-2277

  Nagvekar, Nita ^a   Moody, Anne Marie ^a   Moss, Paul ^a,b   Roxanis, Ioannis ^a   Curnow, John ^a   Beeson, David ^a   Pantic, Nadia ^a   Newsom Davis, John ^a   Vincent, Angela ^a   Willcox, Nicholas ^a  

^a UNIVERSITY OF OXFORD   (United Kingdom)

^b UNIVERSITY OF BIRMINGHAM   (United Kingdom)

Author keywords

Autoimmune T cells; HLA DP; HLA DR isotypes; Paraneoplastic autoimmunity; Thymic epithelium

Indexed keywords

AUTOANTIGEN; CD4 ANTIGEN; CD8 ANTIGEN; CHOLINERGIC RECEPTOR; CHOLINERGIC RECEPTOR ANTIBODY; GAMMA INTERFERON; HLA DP ANTIGEN; HLA DR5 ANTIGEN; INTERLEUKIN 4; PROTEIN SUBUNIT; T LYMPHOCYTE RECEPTOR ALPHA CHAIN; T LYMPHOCYTE RECEPTOR BETA CHAIN;

AMINO ACID SEQUENCE; ANTIGEN EXPRESSION; ANTIGEN PRESENTATION; ANTIGEN RECOGNITION; ARTICLE; AUTOIMMUNITY; CYTOKINE RELEASE; HUMAN; HUMAN CELL; IMMUNOPATHOGENESIS; LYMPHOCYTE CLONE; LYMPHOID CELL LINE; MAJOR HISTOCOMPATIBILITY COMPLEX RESTRICTION; MYASTHENIA GRAVIS; NUCLEOTIDE SEQUENCE; PRIORITY JOURNAL; THYMOMA;

EID: 0032523840     PISSN: 00219738     EISSN: None     Source Type: Journal    
DOI: 10.1172/JCI2068     Document Type: Article

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