Mutation analysis of the WT1 gene in sporadic childhood leukaemia

Leukemia

Volumn 11, Issue 1, 1997, Pages 110-113

  Algar, E ^a   Blackburn, D ^b   Kromykh, T ^b   Taylor, G ^b   Smith, P ^a  

^a ROYAL CHILDREN'S HOSPITAL   (Australia)

^b UNIVERSITY OF QUEENSLAND   (Australia)

Author keywords

Childhood leukaemia; Mutations; Wilms' tumour suppressor gene; WT1

Indexed keywords

DNA;

ACUTE GRANULOCYTIC LEUKEMIA; ACUTE LYMPHOCYTIC LEUKEMIA; ARTICLE; CHILDHOOD LEUKEMIA; CLINICAL ARTICLE; DNA POLYMORPHISM; FEMALE; GENE FREQUENCY; HUMAN; HUMAN CELL; MALE; MUTATION RATE; NEPHROBLASTOMA; POINT MUTATION; PRIORITY JOURNAL; SINGLE STRAND CONFORMATION POLYMORPHISM; TUMOR SUPPRESSOR GENE;

EID: 0031042404     PISSN: 08876924     EISSN: None     Source Type: Journal    
DOI: 10.1038/sj.leu.2400521     Document Type: Article

References (16)

1. Call KM, Glaser T, Ito CY, Buckler AJ, Pelletier J et al. Isolation and characterization of a zinc-finger polypeptide gene at the human chromosome 11 Wilms' tumour locus. Cell 1990; 60: 509-520.
2. Kreidberg JA, Sariola H, Loring JM, Maeda M, Pelletier J, Housman D, Jaenisch R. WT-1 is required for early kidney development. Cell 1993; 74: 679-691.
3. Pritchard-Jones K, Fleming S, Davidson D, Bickmore W, Porteous D, Cosden C et al. The candidate Wilms' tumour gene is involved in genitourinary development. Nature 1990; 346: 194-197.
4. Haber DA, Housman DE. The genetics of Wilms tumour. Adv Cancer Res 1992; 59: 41-68.
5. Pritchard-Jones K, Renshaw J, King-Underwood L. The Wilms tumour (WT1) gene is mutated in a secondary leukaemia in a WAGR patient. Hum Mol Genet 1994; 3: 1633-1637.
6. King-Underwood L, Renshaw J, Pritchard-Jones K. Mutations in the Wilms' tumour gene, WT1, in leukaemias. Blood 1996; 87: 2171-2179.
7. Fraizer G, Patmasiriwat P, Zhang X, Saunders G. Expression of the tumour suppressor gene WT1 in both human and mouse bone marrow. Blood 1995; 86: 4704.
8. Miwa H, Beran M, Saunders GF. Expression of the Wilms' tumour gene (WT1) in human leukaemias. Leukemia 1992; 6: 405-409.
9. Miyagi T, Ahuja H, Kubota T, Kubonishi I, Koeffler H, Miyoshi I. Expression of the candidate Wilms tumour gene, WT1, in human leukaemia cells. Leukemia 1993; 7: 970-977.
10. Phelan SA, Lindberg C, Call KM. Wilms' tumour gene, WT1, mRNA is down-regulated during induction of erythroid and megakaryocytic differentiation of K562 cells. Cell Growth Differ 1994; 5: 677-686.
11. Sekiya M, Adachi M, Hinoda Y, Imai K, Yachi A. Down-regulation of Wilms' tumour gene (wt1) during myelomonocytic differentiation in HL-60 cells. Blood 1994; 83: 1876-1882.
12. Inoue K, Sugiyama H, Ogawa H, Nakagawa M, Yamagami T, Miwa H, Kita K, Hiraoka A, Masaoka T, Nasu K, Kyo T, Dohy H, Nakauchi H, Ishidate T, Akiyama T, Kishimoto T. WT1 as a new prognostic factor and a new marker for the detection of minimal residual disease in acute leukaemia. Blood 1994; 84: 3071-3079.
13. Baird PN, Groves N, Haber DA, Housman DE, Cowell JK. Identification of mutations in the WT1 gene in tumours from patients with the WAGR syndrome. Oncogene 1992; 7: 2141-2149.
14. Chomczynski P, Sacchi N. Single step method of RNA isolation by acid guanidinium thiocyanate-phenol-chloroform extraction. Anal Biochem 1987; 162: 156-159.
15. Kastan MB, Radin AI, Kuerbitz SJ, Onyekwere O, Wolkow CA, Civin CI, Stone KD, Woo T, Ravindranath Y, Craig RW. Levels of p53 protein increase with maturation in human haemopoietic cells. Cancer Res 1991; 51: 4279-4286.
16. Algar EM, Khromykh T, Smith SI, Blackburn DM, Bryson GJ, Smith PJ. A WT1 antisense oligonucleotide inhibits proliferation and induces apoptosis in myeloid leukaemia cell lines. Oncogene 1996; 12: 1005-1014.