Pulsatile stretch in coronary arteries elicits release of endothelium- derived hyperpolarizing factor: A modulator of arterial compliance

Circulation Research

Volumn 82, Issue 6, 1998, Pages 696-703

  Popp, Rüdiger ^a   Fleming, Ingrid ^a   Busse, Rudi ^a  

^a UNIVERSITY HOSPITAL FRANKFURT   (Germany)

Author keywords

Coronary artery; Cytochrome P 450; Endothelium derived hyperpolarizing factor; Mechanotransduction; Transmural pressure

Indexed keywords

6 OXOPROSTAGLANDIN F1 ALPHA; APAMIN; CYTOCHROME P450; DICLOFENAC; ENDOTHELIUM DERIVED HYPERPOLARIZING FACTOR; IBERIOTOXIN; N(G) NITROARGININE; NITRIC OXIDE SYNTHASE INHIBITOR; TETRABUTYLAMMONIUM;

ANIMAL CELL; ARTERY COMPLIANCE; ARTICLE; BLOOD VESSEL DIAMETER; CONTROLLED STUDY; CORONARY ARTERY; HYPERPOLARIZATION; NONHUMAN; PRIORITY JOURNAL; SIGNAL TRANSDUCTION; SWINE; VASCULAR ENDOTHELIUM; VASCULAR SMOOTH MUSCLE;

EID: 0032489925     PISSN: 00097330     EISSN: None     Source Type: Journal    
DOI: 10.1161/01.RES.82.6.696     Document Type: Article

References (43)

1. Chen G, Suzuki H, Weston AH. Acetylcholine releases endotheliumderived hyperpolarizing factor and EDRF from rat blood vessels. Br J Pharmacol. 1988;95:1165-1174.
2. Bauersachs J, Popp R, Hecker M, Sauer E, Fleming I, Busse R. Nitric oxide attenuates the release of endothelium-derived hyperpolarizing factor. Circulation. 1996;94:3314-3347.
3. Rubanyi CM, Vanhoutte PM. Nature of endothelium-derived relaxing factor: are there two relaxing mediators? Circ Res. 1987;61(suppl II):II-61-II-67.
4. 2 and epoxyeicosatrienic acids in relaxation of bovine coronary arteries to arachidonic acid. Am J Physiol. 1993;264:H327-H335.
5. Pinto A, Abraham NG, Mullane KM. Arachidonic acid-induced endothelial-dependent relaxations of canine coronary arteries: contribution of a cytochrome P-450 dependent pathway. J Pharmacol Exp Ther. 1987;240: 856-882.
6. Bauersachs J, Hecker M, Busse R. Display of the characteristics of endothelium-derived hyperpolarizing factor by a cytochrome P450-derived arachidonic acid metabolite in the coronary microcirculation. Br J Pharmacol. 1994;113:1548-1553.
7. Fulton D, Mahboubi K, McGiff JC, Quilley J. Cytochrome P450-dependent effects of bradykinin in the rat heart. Br J Pharmacol. 1995; 114:99-102.
8. Campbell WB, Gebremedhin D, Pratt PF, Harder DR. Identification of epoxyeicosatrienoic acids as endothelium-derived hyperpolarizing factors. Circ Res. 1996;78:415-423.
9. Popp R, Bauersachs J, Hecker M, Fleming I, Busse R. A transferable, β-naphthoflavone-inducible, hyperpolarizing factor is synthesised by native and cultured porcine coronary endothelial cells. J Physiol (Land). 1996;497:699-709.
10. Schabert A, Bauer RD, Busse R. Photoelectric device for the recording of diameter changes of opaque and transparent blood vessels in vitro. Pflugers Arch. 1980;385:239-242.
11. Pohl U, Busse R, Kuon E, Bassenge E. Pulsatile perfusion stimulates the release of endothelial autacoids. J Appl Cardiol. 1986;1:215-235.
12. Koller A, Sun D, Kaley G. Role of shear stress and endothelial prostaglandins in flow- and viscosity-induced dilation of arterioles in vitro. Circ Res. 1993;72:1276-1284.
13. Ayajiki K, Kindermann M, Hecker M, Fleming I, Busse R. Intracellular pH and tyrosine phosphorylation but not calcium determine shear stress- induced nitric oxide production in native endothelial cells. Circ Res. 1996;78:750-758.
14. Grabowski EF, Weksler BB, Jaffe EA. Prostacyclin production by cultured endothelial cell monolayers exposed to step increases in shear stress. J Lab Clin Med. 1985;105:36-43.
15. Lamontagne D, Pohl U, Busse R. Mechanical deformation of the vessel wall and shear stress determine the basal release of endothelium-derived relaxing factor in the intact rabbit coronary vascular bed. Circ Res. 1992;70:123-130.
16. Amezcua JL, Palmer RMJ, de Souza BM, Moncada S. Nitric oxide synthesized from L-arginine regulates vascular tone in the coronary circulation of the rabbit. Br J Pharmacol. 1989;97:1119-1124.
17. G-Nitro-L-arginine antagonizes endothelium-dependent dilator responses by inhibiting endothelium-derived relaxing factor release in the isolated rabbit heart. Pflugers Arch. 1991;418:266-270.
18. Bolotina VM, Najibi S, Palacino JJ, Pagano PJ, Cohen RA. Nitric oxide directly activates calcium-dependent potassium channels in vascular smooth muscle. Nature. 1994;368:850-853.
19. Parkington HC, Tare M, Tonta MA, Coleman HA. Stretch revealed three components in the hyperpolarization of guinea-pig coronary artery in response to acetylcholine. J Physiol (Lond). 1993;465:459-476.
20. Brayden JE. Membrane hyperpolarization is a mechanism of endothelium-dependent cerebral vasodilation. Am J Physiol. 1990;259: H668-H673.
21. Komori K, Lorenz. RR, Vanhoutte PM. Nitric oxide, ACh, and electrical and mechanical properties of canine arterial smooth muscle. Am J Physiol. 1988;255:143-150.
22. Huang AH, Busse R, Bassenge E. Endothelium-dependent hyperpolarization of smooth muscle cells in rabbit femoral arteries is not mediated by EDRF (nitric oxide). Naunyn Schmiedebergs Arch Pharmacol. 1988;338:438-442.
23. Cohen RA, Plane F, Najibi S, Huk I, Malinski T, Garland CJ. Nitric oxide is the mediator of both endothelium-dependent relaxation and hyperpolarization of the rabbit carotid artery. Proc Natl Acad Sci U S A. 1997;94:4193-4198.
24. McCulloch AI, Bottrill FE, Randall MD, Hiley CR. Characterization and modulation of EDHF-mediated relaxations in the rat isolated superior mesenteric arterial bed. Br J Pharmacol. 1997;120:1431-1438.
25. Harder DR, Lange AR, Gebremedhin D, Birks EK, Roman RJ. Cytochrome P450 metabolites of arachidonic acid as intracellular signaling molecules in vascular tissue. J Vasc Res. 1997;34:237-243.
26. Ma Y-H, Gebremedhin D, Schwartzman M, Falck JR, Masters BS, Harder DR, Roman RJ. 20-Hydroxyeicosatetraenoic acid is an endogenous vasoconstrictor of canine renal arcuate arteries. Circ Res. 1993;72:126-136.
27. + channel in renal arterioles. Am J Physiol. 1996;270:R228-R237.
28. Imig JD, Zou AP, Stec DE, Harder DR, Falck JR, Roman RJ. Formation and actions of 20-hydroxyeicosatetraenoic acid in rat renal arterioles. Am J Physiol. 1996;270:R2I7-R227.
29. Helmlinger G, Berk BC, Nerem RM. Calcium responses of endothelial cell monolayers subjected to pulsatile and steady laminar flow differ. Am J Physiol. 1995;269:C367-C375.
30. Fleming I, Baucrsachs J, Busse R. Calcium-dependent and -independent activation of the endothelial NO synthase. V Vasc Res. 1997;34:165-174.
31. Hecker M, Bara AT, Bauersachs J, Busse R. Characterization of endothelium-derived hyperpolarizing factor as a cytochrome P450-derived arachidonic acid metabolite in mammals. J Physiol (Lond). 1994;481:407-414.
32. + channels by cytochrome P-450 inhibitors. J Biol Chem. 1992;267:11789-11793.
33. Zygmunt PM, Edwards G, Weston AH, Davis SC, Högestätt ED. Effects of cytochrome P450 inhibitors on EDHF-mediated relaxation in the rat hepatic artery. Br J Pharmacol. 1996;118:1147-1152.
34. Edwards G, Zygmunt PM, Högestätt ED, Weston AH. Effects of cytochrome P450 inhibitors on potassium currents and mechanical activity in rat portal vein. Br J Pharmacol. 1996;119:691-701.
35. 2+ entry in human and bovine endothelial cells. J Physiol (Lond). 1995;482:259-274.
36. Oyekan AO, McGiff JC, Rosenkranz-Weiss P, Quilley J. Relaxant responses of rabbit aorta: influence of P450 inhibitors. J Pharmacol Exp Ther. 1994;268:262-269.
37. Corriu C, Félétou M, Canet E, Vanhoutte PM. Inhibitors of the cytochrome P450-mono-oxygenase and endothelium-dependent hyperpolarizations in the guinea-pig isolated carotid artery. Br J Pharmacol. 1996;117:607-610.
38. Fukao M, Hattori Y, Kanno M, Sakuma I, Kitabatake A. Evidence against a role of cytochrome P450-derived arachidonic acid metabolites in endothelium-dependent hyperpolarization by acetylcholine in rat isolated mesenteric artery. Br J Pharmacol. 1997;120:439-446.
39. Devane WA, Hanus L. Breuer A, Pertwee RG, Stevenson LA, Griffin G, Gibson D, Mandelbaum A, Hunger A. Mechoulam R. Isolation and structure of a brain constituent that binds to the cannabinoid receptor. Science. 1992;258:1946-1949.
40. Felder CC, Briley EM, Axelrod J, Simpson JT, Mackie K, Devane WA. Anandamide, an endogenous cannabimimetic eicosanoid, binds to the cloned human cannabinoid receptor and stimulates receptormediated signal transduction. Proc Natl Acad Sci U S A. 1993;90:7656-7660.
41. Randall MD, Alexander SPH, Bennett T, Boyd EA, Fry JR, Gardiner SM, Kemp PA, McCulloch AI, Kendall DA. An endogenous cannabinoid as an endothelium-derived vasorelaxant. Biochem Biophys Res Commun. 1996;229:114-120.
42. Di Marzo V, Fontana A. Anandamide, an endogenous cannabinomimetic eicosanoid: 'killing two birds with one stone'. Prostaglandins Leukot Essent Fatty Acids. 1995;53:1-11.
43. Bornheim LM, Kim KY, Chen B, Correia MA. Microsomal cytochrome P450-mediated liver and brain metabolism. Biochem Pharmacol. 1995; 50:677-686.