Half-site reactivity, negative cooperativity, and positive cooperativity: Quantitative considerations of a plausible model

Biochemistry

Volumn 36, Issue 42, 1997, Pages 12759-12765

  Bloom, Curtis R ^a,c   Kaarsholm, Niels C ^b   Ha, Julie ^a   Dunn, Michael F ^a  

^a UNIVERSITY OF CALIFORNIA   (United States)

^b NOVO NORDISK A S   (Denmark)

^c CALIFORNIA INSTITUTE OF TECHNOLOGY   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

RECOMBINANT HUMAN INSULIN;

ARTICLE; BINDING AFFINITY; BINDING SITE; COMPUTER SIMULATION; CRYSTAL STRUCTURE; DISSOCIATION CONSTANT; HORMONE BINDING; HUMAN; LIGAND BINDING; MOLECULAR MODEL; PRIORITY JOURNAL;

ALLOSTERIC REGULATION; ALLOSTERIC SITE; HEMOGLOBINS; HUMANS; INSULIN; KINETICS; LIGANDS; MACROMOLECULAR SUBSTANCES; MODELS, CHEMICAL; OXYHEMOGLOBINS; PHENOLS; PROTEIN CONFORMATION;

EID: 0030722962     PISSN: 00062960     EISSN: None     Source Type: Journal    
DOI: 10.1021/bi970762f     Document Type: Article

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