Mechanisms of stabilization of the insulin hexamer through allosteric ligand interactions

Biochemistry

Volumn 36, Issue 19, 1997, Pages 5837-5845

  Rahuel Clermont, Sophie ^a   French, Cherie A ^a   Kaarsholm, Niels C ^b   Dunn, Michael F ^a  

^a UNIVERSITY OF CALIFORNIA   (United States)

^b NOVO NORDISK A S   (Denmark)

Author keywords

[No Author keywords available]

Indexed keywords

COPPER; HUMAN INSULIN; PHENOL DERIVATIVE; POTASSIUM CHLORIDE; RESORCINOL; THIOCYANATE POTASSIUM; ZINC;

ARTICLE; BINDING AFFINITY; BINDING KINETICS; DRUG FORMULATION; HUMAN; INSULIN DEPENDENT DIABETES MELLITUS; INSULIN TREATMENT; LIGAND BINDING; PRIORITY JOURNAL; PROTEIN ANALYSIS; PROTEIN STABILITY; THERMODYNAMICS;

ALLOSTERIC REGULATION; CHELATING AGENTS; COBALT; INSULIN; KINETICS; LIGANDS; PHENOLS; PROTEIN CONFORMATION; PROTEIN STRUCTURE, TERTIARY; PYRIDINES; THERMODYNAMICS; ZINC;

EID: 0031010619     PISSN: 00062960     EISSN: None     Source Type: Journal    
DOI: 10.1021/bi963038q     Document Type: Article

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