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Volumn 404, Issue 1-2, 1998, Pages 155-165

Important variables that influence base-line micronucleus frequency in cytokinesis-blocked lymphocytes - A biomarker for DNA damage in human populations

Author keywords

Age; Apoptosis; Cytokinesis block; Cytokinesis block method; Gender; Homocysteine; HUMN project; Lymphocyte; Micronucleus; Variable; Vitamin B12

Indexed keywords

BIOLOGICAL MARKER; CYANOCOBALAMIN; HOMOCYSTEINE;

EID: 0032480029     PISSN: 00275107     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0027-5107(98)00109-2     Document Type: Conference Paper
Times cited : (187)

References (34)
  • 1
    • 0021987630 scopus 로고
    • Measurement of micronuclei in human lymphocytes
    • [1] M. Fenech, A.A. Morley, Measurement of micronuclei in human lymphocytes, Mutat. Res. 148 (1985) 29-36.
    • (1985) Mutat. Res. , vol.148 , pp. 29-36
    • Fenech, M.1    Morley, A.A.2
  • 2
    • 0022589981 scopus 로고
    • Cytokinesis-block micronucleus method in human lymphocytes: Effect of in vivo ageing and low-dose X-irradiation
    • [2] M. Fenech, A.A. Morley, Cytokinesis-block micronucleus method in human lymphocytes: effect of in vivo ageing and low-dose X-irradiation, Mutat. Res. 161 (1986) 193-198.
    • (1986) Mutat. Res. , vol.161 , pp. 193-198
    • Fenech, M.1    Morley, A.A.2
  • 3
    • 0027763463 scopus 로고
    • The cytokinesis-block micronucleus technique and its application to genotoxicity studies in human populations
    • [3] M. Fenech, The cytokinesis-block micronucleus technique and its application to genotoxicity studies in human populations, Environ. Health Perspect. 101 (1993) 101-107.
    • (1993) Environ. Health Perspect. , vol.101 , pp. 101-107
    • Fenech, M.1
  • 4
    • 0030805031 scopus 로고    scopus 로고
    • The in vitro micronucleus test: A multi-end-point assay to detect simultaneously mitotic delay, apoptosis, chromosome breakage, chromosome loss and non-disjunction
    • [4] M. Kirsch-Volders, A. Elhajouji, E. Cundari, P. Van Hummelen, The in vitro micronucleus test: a multi-end-point assay to detect simultaneously mitotic delay, apoptosis, chromosome breakage, chromosome loss and non-disjunction, Mutat. Res. 392 (1997) 19-30.
    • (1997) Mutat. Res. , vol.392 , pp. 19-30
    • Kirsch-Volders, M.1    Elhajouji, A.2    Cundari, E.3    Van Hummelen, P.4
  • 5
    • 0030840634 scopus 로고    scopus 로고
    • The advantages and disadvantages of the cytokinesis-block micronucleus method
    • [5] M. Fenech, The advantages and disadvantages of the cytokinesis-block micronucleus method, Mutat. Res. 392 (1997) 11-18.
    • (1997) Mutat. Res. , vol.392 , pp. 11-18
    • Fenech, M.1
  • 7
    • 0030748286 scopus 로고    scopus 로고
    • Historical perspectives on the development of the in vitro micronucleus test: A personal view
    • [7] H.J. Evans, Historical perspectives on the development of the in vitro micronucleus test: a personal view, Mutat. Res. 392 (1997) 5-10.
    • (1997) Mutat. Res. , vol.392 , pp. 5-10
    • Evans, H.J.1
  • 8
    • 0031202390 scopus 로고    scopus 로고
    • Towards a validation of the micronucleus test
    • [8] M. Kirsch-Volders, Towards a validation of the micronucleus test, Mutat. Res. 392 (1997) 1-4.
    • (1997) Mutat. Res. , vol.392 , pp. 1-4
    • Kirsch-Volders, M.1
  • 9
    • 0030851298 scopus 로고    scopus 로고
    • A critical evaluation of centromeric labelling to distinguish micronuclei induced by chromosomal loss and breakage in vitro
    • [9] M. Schuler, D.S. Rupa, D.A. Eastmond, A critical evaluation of centromeric labelling to distinguish micronuclei induced by chromosomal loss and breakage in vitro, Mutat. Res. 392 (1997) 81-95.
    • (1997) Mutat. Res. , vol.392 , pp. 81-95
    • Schuler, M.1    Rupa, D.S.2    Eastmond, D.A.3
  • 10
    • 0027763463 scopus 로고
    • The cytokinesis-block micronucleus technique and its application to genotoxicity studies in human populations
    • [10] M. Fenech, The cytokinesis-block micronucleus technique and its application to genotoxicity studies in human populations, Environ. Health Perspect. 101 (1993) 101-107.
    • (1993) Environ. Health Perspect. , vol.101 , pp. 101-107
    • Fenech, M.1
  • 13
    • 0028178038 scopus 로고
    • The effect of cytochalasin-B concentration on the frequency of micronuclei induced by four standard mutagens: Results from two laboratories
    • [13] J. Surralles, A. Antoccia, A. Creus, F. Degrassi, F. Peris, C. Tanzarella, N. Xamena, R. Marcos, The effect of cytochalasin-B concentration on the frequency of micronuclei induced by four standard mutagens: results from two laboratories, Mutagenesis 9 (1994) 347-353.
    • (1994) Mutagenesis , vol.9 , pp. 347-353
    • Surralles, J.1    Antoccia, A.2    Creus, A.3    Degrassi, F.4    Peris, F.5    Tanzarella, C.6    Xamena, N.7    Marcos, R.8
  • 14
    • 0027497435 scopus 로고
    • The cytokinesis-block micronucleus technique: A detailed description of the method and its application to genotoxicity studies in human populations
    • [14] M. Fenech, The cytokinesis-block micronucleus technique: a detailed description of the method and its application to genotoxicity studies in human populations, Mutat. Res. 285 (1993) 35-44.
    • (1993) Mutat. Res. , vol.285 , pp. 35-44
    • Fenech, M.1
  • 15
    • 0030787379 scopus 로고    scopus 로고
    • Human lymphocyte micronucleus assay in Europe: An international survey
    • [15] J. Surrales, A.T. Natarajan, Human lymphocyte micronucleus assay in Europe: an international survey, Mutat. Res. 392 (1997) 165-174.
    • (1997) Mutat. Res. , vol.392 , pp. 165-174
    • Surrales, J.1    Natarajan, A.T.2
  • 16
    • 0029116639 scopus 로고
    • Sources of variability in the human lymphocyte micronucleus assay: A population-based study
    • [16] K.L. Radack, S.M. Pinney, G.K. Livingston, Sources of variability in the human lymphocyte micronucleus assay: a population-based study, Environ. Mol. Mutagen. 26 (1995) 26-36.
    • (1995) Environ. Mol. Mutagen. , vol.26 , pp. 26-36
    • Radack, K.L.1    Pinney, S.M.2    Livingston, G.K.3
  • 17
    • 0030915153 scopus 로고    scopus 로고
    • Sources of variability in the determination of micronuclei in irradiated peripheral blood lymphocytes
    • [17] J.K. Brown, A. Williams, H.R. Withers, K.T. Ow, C. Gramacho, C. Amies, Sources of variability in the determination of micronuclei in irradiated peripheral blood lymphocytes, Mutat. Res. 389 (1997) 123-128.
    • (1997) Mutat. Res. , vol.389 , pp. 123-128
    • Brown, J.K.1    Williams, A.2    Withers, H.R.3    Ow, K.T.4    Gramacho, C.5    Amies, C.6
  • 18
    • 0025896306 scopus 로고
    • Chromosome aberrations, sister chromatid exchanges and mitogen-induced blastogenesis in cultured peripheral blood lymphocytes from 48 control individuals sampled 8 times over two years
    • [18] D. Anderson, A.J. Francis, P. Godbert, P.C. Jenkinson, K.R. Butterworth, Chromosome aberrations, sister chromatid exchanges and mitogen-induced blastogenesis in cultured peripheral blood lymphocytes from 48 control individuals sampled 8 times over two years, Mutat. Res. 250 (1991) 467-476.
    • (1991) Mutat. Res. , vol.250 , pp. 467-476
    • Anderson, D.1    Francis, A.J.2    Godbert, P.3    Jenkinson, P.C.4    Butterworth, K.R.5
  • 21
    • 0027322875 scopus 로고
    • Radiosensitivity of atomic bomb survivors as determined with a micronucleus assay
    • [21] S. Ban, J.B. Cologne, S. Fujita, A.A. Awa, Radiosensitivity of atomic bomb survivors as determined with a micronucleus assay, Radiat. Res. 134 (1993) 170-178.
    • (1993) Radiat. Res. , vol.134 , pp. 170-178
    • Ban, S.1    Cologne, J.B.2    Fujita, S.3    Awa, A.A.4
  • 22
    • 0028895586 scopus 로고
    • A comparison of lymphocyte micronuclei and plasma micronutrients in vegetarians and non-vegetarians
    • [22] M. Fenech, J. Rinaldi, A comparison of lymphocyte micronuclei and plasma micronutrients in vegetarians and non-vegetarians, Carcinogenesis 16 (1995) 223-230.
    • (1995) Carcinogenesis , vol.16 , pp. 223-230
    • Fenech, M.1    Rinaldi, J.2
  • 23
    • 0028321644 scopus 로고
    • The relationship between micronuclei in human lymphocytes and plasma levels of vitamin-C, vitamin-E, vitamin-B12 and folic acid
    • [23] M. Fenech, J. Rinaldi, The relationship between micronuclei in human lymphocytes and plasma levels of vitamin-C, vitamin-E, vitamin-B12 and folic acid, Carcinogenesis 15 (1994) 1405-1411.
    • (1994) Carcinogenesis , vol.15 , pp. 1405-1411
    • Fenech, M.1    Rinaldi, J.2
  • 24
    • 0031426131 scopus 로고    scopus 로고
    • Vitamin-E supplements and their effect on vitamin-E status in blood and genetic damage rate in peripheral blood lymphocytes
    • [24] M. Fenech, I. Dreosti, C. Aitken, Vitamin-E supplements and their effect on vitamin-E status in blood and genetic damage rate in peripheral blood lymphocytes, Carcinogenesis 18 (1997) 359-364.
    • (1997) Carcinogenesis , vol.18 , pp. 359-364
    • Fenech, M.1    Dreosti, I.2    Aitken, C.3
  • 25
    • 0031410993 scopus 로고    scopus 로고
    • Folate, vitamin B12, homocysteine status and chromosome damage rate in lymphocytes of older men
    • [25] M. Fenech, I.E. Dreosti, J.R. Rinaldi, Folate, vitamin B12, homocysteine status and chromosome damage rate in lymphocytes of older men, Carcinogenesis 18 (1997) 1329-1336.
    • (1997) Carcinogenesis , vol.18 , pp. 1329-1336
    • Fenech, M.1    Dreosti, I.E.2    Rinaldi, J.R.3
  • 26
    • 0029066299 scopus 로고
    • A quantitative assessment of plasma homocysteine as a risk factor for vascular disease: Probable benefits of increasing folic acid intakes
    • [26] C.J. Boushey, S.A.A. Beresford, G.S. Omenn, A.G. Motulsky, A quantitative assessment of plasma homocysteine as a risk factor for vascular disease: probable benefits of increasing folic acid intakes, JAMA 274 (1995) 1049-1057.
    • (1995) JAMA , vol.274 , pp. 1049-1057
    • Boushey, C.J.1    Beresford, S.A.A.2    Omenn, G.S.3    Motulsky, A.G.4
  • 27
    • 0342624737 scopus 로고    scopus 로고
    • Homocysteine mediated endothelial cell toxicity and its amelioration
    • [27] G. Blundell, B.G. Jones, F.A. Rose, N. Tudball, Homocysteine mediated endothelial cell toxicity and its amelioration, Atherosclerosis 122 (1996) 163-172.
    • (1996) Atherosclerosis , vol.122 , pp. 163-172
    • Blundell, G.1    Jones, B.G.2    Rose, F.A.3    Tudball, N.4
  • 28
    • 0030610589 scopus 로고    scopus 로고
    • Inhibition of growth and p21 ras methylation in vascular endothelial cells by homocysteine but not cysteine
    • [28] H. Wang, M. Yoshizumi, K. Lai, J.C. Tsai, M.A. Perella, E. Haber, M.E. Lee, Inhibition of growth and p21 ras methylation in vascular endothelial cells by homocysteine but not cysteine, J. Biol. Chem. 272 (1997) 23580-25385.
    • (1997) J. Biol. Chem. , vol.272 , pp. 23580-25385
    • Wang, H.1    Yoshizumi, M.2    Lai, K.3    Tsai, J.C.4    Perella, M.A.5    Haber, E.6    Lee, M.E.7
  • 29
    • 0030774496 scopus 로고    scopus 로고
    • A more comprehensive application of the micronucleus technique for biomonitoring of genetic damage rates in human populations: Experiences from the Chernobyl catastrophe
    • [29] M. Fenech, G. Perepetskaya, L. Mikhalevich, A more comprehensive application of the micronucleus technique for biomonitoring of genetic damage rates in human populations: experiences from the Chernobyl catastrophe, Environ. Mol. Mutagen. 30 (1997) 112-118.
    • (1997) Environ. Mol. Mutagen. , vol.30 , pp. 112-118
    • Fenech, M.1    Perepetskaya, G.2    Mikhalevich, L.3
  • 30
    • 0031975834 scopus 로고    scopus 로고
    • Radiation-induced micronucleus induction in lymphocytes identifies a high frequency of radiosensitive cases amongst breast cancer patients: A test for predisposition
    • [30] D. Scott, J.B.P. Barber, E.L. Levine, W. Burril, S.A. Roberts, Radiation-induced micronucleus induction in lymphocytes identifies a high frequency of radiosensitive cases amongst breast cancer patients: a test for predisposition, Br. J. Cancer 77 (1998) 614-620.
    • (1998) Br. J. Cancer , vol.77 , pp. 614-620
    • Scott, D.1    Barber, J.B.P.2    Levine, E.L.3    Burril, W.4    Roberts, S.A.5
  • 32
    • 0030629863 scopus 로고    scopus 로고
    • Transitional studies
    • P. Toniolo, P. Boffetta, D.E.G. Shuker, N. Rothman, B. Hulka, N. Pearce (Eds.), IARC Scientific Publications International Agency for Research on Cancer, Lyon
    • [32] P.A. Schulte, F. Perera, Transitional studies, in: P. Toniolo, P. Boffetta, D.E.G. Shuker, N. Rothman, B. Hulka, N. Pearce (Eds.), Application of Biomarkers in Cancer Epidemiology, IARC Scientific Publications No. 142, International Agency for Research on Cancer, Lyon, 1997, pp. 19-29.
    • (1997) Application of Biomarkers in Cancer Epidemiology , vol.142 , pp. 19-29
    • Schulte, P.A.1    Perera, F.2


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