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Volumn 392, Issue 1-2, 1997, Pages 11-18

The advantages and disadvantages of the cytokinesis-block micronucleus method

Author keywords

Advantage; Cytokinesis block technique; Disadvantage; In vitro; Micronucleus test

Indexed keywords

HYPOXANTHINE PHOSPHORIBOSYLTRANSFERASE;

EID: 0030840634     PISSN: 13835718     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0165-1218(97)00041-4     Document Type: Article
Times cited : (227)

References (38)
  • 2
    • 0028964622 scopus 로고
    • Image processing algorithms for the automated micronucleus assay in binucleated human lymphocytes
    • Bocker, W., Muller, W.U., Streffer, C., 1995. Image processing algorithms for the automated micronucleus assay in binucleated human lymphocytes. Cytometry 19 (4), 283-294.
    • (1995) Cytometry , vol.19 , Issue.4 , pp. 283-294
    • Bocker, W.1    Muller, W.U.2    Streffer, C.3
  • 3
    • 0014212637 scopus 로고
    • Effects of cytochalasins on mammalian cells
    • Carter, S.B., 1967. Effects of cytochalasins on mammalian cells. Nature 213, 261-264.
    • (1967) Nature , vol.213 , pp. 261-264
    • Carter, S.B.1
  • 4
    • 0027171487 scopus 로고
    • Automated detection of cytochalasin-B blocked binucleated lymphocytes for scoring micronuclei
    • Castelain, P., Van Hummelen, P., Deleneer, A., Kirsch-Volders, M., 1993. Automated detection of cytochalasin-B blocked binucleated lymphocytes for scoring micronuclei. Mutagenesis 8 (4), 285-293.
    • (1993) Mutagenesis , vol.8 , Issue.4 , pp. 285-293
    • Castelain, P.1    Van Hummelen, P.2    Deleneer, A.3    Kirsch-Volders, M.4
  • 5
    • 0024461337 scopus 로고
    • Identification of aneuploidy-inducing agents using cytokinesis-blocked human lymphocytes and an anti-kinetochore antibody
    • Eastmond, D.A., Tucker, J.D., 1989. Identification of aneuploidy-inducing agents using cytokinesis-blocked human lymphocytes and an anti-kinetochore antibody. Environ. Mol. Mutagen. 13, 34-43.
    • (1989) Environ. Mol. Mutagen. , vol.13 , pp. 34-43
    • Eastmond, D.A.1    Tucker, J.D.2
  • 6
    • 0023928521 scopus 로고
    • Mutation cytogenetics: Past, present and future
    • Evans, H.J., 1988. Mutation cytogenetics: past, present and future. Mutation Res. 204, 355-363.
    • (1988) Mutation Res. , vol.204 , pp. 355-363
    • Evans, H.J.1
  • 7
    • 0027244839 scopus 로고
    • Use of fluorescence in situ hybridisation for the detection of aneugens in cytokinesis-blocked mouse splenocytes
    • Farooqi, Z., Darroudi, F., Natarajan, A.T., 1993. Use of fluorescence in situ hybridisation for the detection of aneugens in cytokinesis-blocked mouse splenocytes. Mutagenesis 8, 329-334.
    • (1993) Mutagenesis , vol.8 , pp. 329-334
    • Farooqi, Z.1    Darroudi, F.2    Natarajan, A.T.3
  • 9
    • 0022203364 scopus 로고
    • Solutions to the kinetic problem in the micronucleus assay
    • Fenech, M., Morley, A., 1985a. Solutions to the kinetic problem in the micronucleus assay. Cytobios 43, 233-246.
    • (1985) Cytobios , vol.43 , pp. 233-246
    • Fenech, M.1    Morley, A.2
  • 10
    • 0021923142 scopus 로고
    • The effect of donor age on spontaneous and induced micronuclei
    • Fenech, M., Morley, A., 1985b. The effect of donor age on spontaneous and induced micronuclei. Mutation Res. 148, 99-105.
    • (1985) Mutation Res. , vol.148 , pp. 99-105
    • Fenech, M.1    Morley, A.2
  • 11
    • 0021987630 scopus 로고
    • Measurement of micronuclei in lymphocytes
    • Fenech, M., Morley, A., 1985c. Measurement of micronuclei in lymphocytes. Mutation Res. 147, 29-36.
    • (1985) Mutation Res. , vol.147 , pp. 29-36
    • Fenech, M.1    Morley, A.2
  • 12
    • 0024523360 scopus 로고
    • Kinetochore detection in micronuclei: An alternative method for measuring chromosome loss
    • Fenech, M., Morley, A., 1989. Kinetochore detection in micronuclei: an alternative method for measuring chromosome loss. Mutagenesis 4 (2), 98-104.
    • (1989) Mutagenesis , vol.4 , Issue.2 , pp. 98-104
    • Fenech, M.1    Morley, A.2
  • 13
    • 0026274771 scopus 로고
    • Optimisation of micronucleus assays for biological dosimetry
    • B.L. Gledhill, F. Mauro (Eds.), Wiley-Liss
    • M. Fenech, Optimisation of micronucleus assays for biological dosimetry, in: B.L. Gledhill, F. Mauro (Eds.), New Horizons in Biological Dosimetry, Wiley-Liss, 1991, pp. 373-386.
    • (1991) New Horizons in Biological Dosimetry , pp. 373-386
    • Fenech, M.1
  • 14
    • 0026593221 scopus 로고
    • Conversion of excision-repairable DNA lesions to micronuclei within one cell cycle in human lymphocytes
    • Fenech, M., Neville, S., 1992. Conversion of excision-repairable DNA lesions to micronuclei within one cell cycle in human lymphocytes. Environ. Mol. Mutagen. 19 (1), 27-36.
    • (1992) Environ. Mol. Mutagen. , vol.19 , Issue.1 , pp. 27-36
    • Fenech, M.1    Neville, S.2
  • 15
    • 0028177356 scopus 로고
    • The origin of micronuclei induced by cytosine arabinoside and its synergistic interaction with hydroxyurea in human lymphocytes
    • Fenech, M., Rinaldi, J., Surrallés, J., 1994. The origin of micronuclei induced by cytosine arabinoside and its synergistic interaction with hydroxyurea in human lymphocytes. Mutagenesis 9 (3), 273-277.
    • (1994) Mutagenesis , vol.9 , Issue.3 , pp. 273-277
    • Fenech, M.1    Rinaldi, J.2    Surrallés, J.3
  • 16
    • 0028225730 scopus 로고
    • J.C. Hando et al., Chromosoma 105 (1994) 186-192.
    • (1994) Chromosoma , vol.105 , pp. 186-192
    • Hando, J.C.1
  • 18
    • 0025202628 scopus 로고
    • Cytochalasin B induces cellular DNA fragmentation
    • Kolber, M.A., Broschat, K.O., Landa-Gonzalez, B., 1990. Cytochalasin B induces cellular DNA fragmentation. FASEB J. 4, 3021-3027.
    • (1990) FASEB J. , vol.4 , pp. 3021-3027
    • Kolber, M.A.1    Broschat, K.O.2    Landa-Gonzalez, B.3
  • 20
    • 0343752742 scopus 로고
    • Actin polymerisation induced by a motility-related high-affinity cytochalasin binding complex from human erythrocyte membrane
    • Lin, C.D., Lin, S., 1979. Actin polymerisation induced by a motility-related high-affinity cytochalasin binding complex from human erythrocyte membrane. Proc. Natl. Acad. Sci. USA 76 (5), 2345-2349.
    • (1979) Proc. Natl. Acad. Sci. USA , vol.76 , Issue.5 , pp. 2345-2349
    • Lin, C.D.1    Lin, S.2
  • 21
    • 0025862246 scopus 로고
    • Induction of micronuclei and anaphase aberrations by cytochalasin-B in human lymphocyte cultures
    • Linholm, C., Norrpa, H., Hayashi, M., Sorsa, M., 1991. Induction of micronuclei and anaphase aberrations by cytochalasin-B in human lymphocyte cultures. Mutation Res. 260, 369-375.
    • (1991) Mutation Res. , vol.260 , pp. 369-375
    • Linholm, C.1    Norrpa, H.2    Hayashi, M.3    Sorsa, M.4
  • 22
    • 0027299878 scopus 로고
    • The cytochalasin-B micronucleus/kinetochore assay in vitro: Studies with 10 suspected aneugens
    • Lynch, A.M., Parry, J.M., 1993. The cytochalasin-B micronucleus/kinetochore assay in vitro: studies with 10 suspected aneugens. Mutation Res. 287 (1), 71-87.
    • (1993) Mutation Res. , vol.287 , Issue.1 , pp. 71-87
    • Lynch, A.M.1    Parry, J.M.2
  • 23
    • 0028111378 scopus 로고
    • Induction of binucleation in human lymphocytes by 14 synthetic isoindolone derivatives related to cytochalasins
    • Migliore, L., Pistelli, L., Papa, S., Andreassi, M.G., Balata, T., Benassi, S., 1994. Induction of binucleation in human lymphocytes by 14 synthetic isoindolone derivatives related to cytochalasins. Mutation Res. 313 (1), 89-97.
    • (1994) Mutation Res. , vol.313 , Issue.1 , pp. 89-97
    • Migliore, L.1    Pistelli, L.2    Papa, S.3    Andreassi, M.G.4    Balata, T.5    Benassi, S.6
  • 24
    • 0023908495 scopus 로고
    • A sensitive assay for 6-thioguanine-resistant lymphocytes
    • Norman, A., Cameron Mitchell, J., Iwamoto, K.S., 1988. A sensitive assay for 6-thioguanine-resistant lymphocytes. Mutation Res. 208, 17-19.
    • (1988) Mutation Res. , vol.208 , pp. 17-19
    • Norman, A.1    Cameron Mitchell, J.2    Iwamoto, K.S.3
  • 25
    • 0028980552 scopus 로고
    • Extended-term cultures of human T-lymphocytes: A practical alternative to primary human lymphocytes for use in genotoxicity testing
    • O'Donovan, M.R., Freemantle, M.R., Hull, G., Bell, D.A., Arlett, C.F., Cole, J., 1995. Extended-term cultures of human T-lymphocytes: a practical alternative to primary human lymphocytes for use in genotoxicity testing. Mutagenesis 10 (3), 189-201.
    • (1995) Mutagenesis , vol.10 , Issue.3 , pp. 189-201
    • O'Donovan, M.R.1    Freemantle, M.R.2    Hull, G.3    Bell, D.A.4    Arlett, C.F.5    Cole, J.6
  • 26
    • 0028894366 scopus 로고
    • Procedures for the detection of chemically induced aneuploidy: Recommendations of a UK Environmental Mutagen Society working group
    • Parry, E.M., Henderson, L., Mackay, J.M., 1995. Procedures for the detection of chemically induced aneuploidy: recommendations of a UK Environmental Mutagen Society working group. Mutagenesis 10 (1), 1-14.
    • (1995) Mutagenesis , vol.10 , Issue.1 , pp. 1-14
    • Parry, E.M.1    Henderson, L.2    Mackay, J.M.3
  • 27
    • 0021330287 scopus 로고
    • An improved micronuclear assay in lymphocytes
    • Pincu, M., Bass, D., Norman, A., 1984. An improved micronuclear assay in lymphocytes. Mutation Res. 139, 61-65.
    • (1984) Mutation Res. , vol.139 , pp. 61-65
    • Pincu, M.1    Bass, D.2    Norman, A.3
  • 29
    • 0029116639 scopus 로고
    • Sources of variability in the human lymphocyte micronucleus assay: A population-based study
    • Radack, K.L., Pinney, S.M., Livingston, G.K., 1995. Sources of variability in the human lymphocyte micronucleus assay: a population-based study. Environ. Mol. Mutagen. 26 (1), 26-36.
    • (1995) Environ. Mol. Mutagen. , vol.26 , Issue.1 , pp. 26-36
    • Radack, K.L.1    Pinney, S.M.2    Livingston, G.K.3
  • 30
    • 0024653076 scopus 로고
    • Acentric chromosomal fragments and micronuclei: The time-displacement factor
    • Savage, J.R.K., 1989. Acentric chromosomal fragments and micronuclei: the time-displacement factor. Mutation Res. 225, 171-173.
    • (1989) Mutation Res. , vol.225 , pp. 171-173
    • Savage, J.R.K.1
  • 31
    • 0028174376 scopus 로고
    • Video time-lapse study of mitosis in binucleate V79 cells: Chromosome segregation and cleavage
    • Schultz, N., Onfelt, A., 1994. Video time-lapse study of mitosis in binucleate V79 cells: chromosome segregation and cleavage. Mutagenesis 9 (2), 117-123.
    • (1994) Mutagenesis , vol.9 , Issue.2 , pp. 117-123
    • Schultz, N.1    Onfelt, A.2
  • 32
    • 0018380453 scopus 로고
    • Enumeration of 6-thioguanine resistant peripheral blood lymphocytes in man as a potential test for somatic cell mutation arising in vivo
    • Strauss, G.H., Albertini, R.J., 1979. Enumeration of 6-thioguanine resistant peripheral blood lymphocytes in man as a potential test for somatic cell mutation arising in vivo. Mutation Res. 61, 353-379.
    • (1979) Mutation Res. , vol.61 , pp. 353-379
    • Strauss, G.H.1    Albertini, R.J.2
  • 33
    • 0026440760 scopus 로고
    • A collaborative study on the improvement of the micronucleus test in cultured human lymphocytes
    • Surrallés, J., Carbonell, E., Marcos, R., Degrassi, F., Antoccia, A., Tanzarella, C., 1992. A collaborative study on the improvement of the micronucleus test in cultured human lymphocytes. Mutagenesis 7 (6), 407-410.
    • (1992) Mutagenesis , vol.7 , Issue.6 , pp. 407-410
    • Surrallés, J.1    Carbonell, E.2    Marcos, R.3    Degrassi, F.4    Antoccia, A.5    Tanzarella, C.6
  • 34
    • 0028907998 scopus 로고
    • The suitability of the micronucleus assay in human lymphocytes as a new biomarker of excision repair
    • Surrallés, J., Xamena, N., Creus, A., Marcos, R., 1995. The suitability of the micronucleus assay in human lymphocytes as a new biomarker of excision repair. Mutation Res. 341 (1-2), 43-59.
    • (1995) Mutation Res. , vol.341 , Issue.1-2 , pp. 43-59
    • Surrallés, J.1    Xamena, N.2    Creus, A.3    Marcos, R.4
  • 35
    • 0025123909 scopus 로고
    • The present state of the automated micronucleus test for lymphocytes
    • Tates, A.N., van Welie, M.T., Ploem, J.S., 1990. The present state of the automated micronucleus test for lymphocytes. Int. J. Radiat. Biol. 58, 813-825.
    • (1990) Int. J. Radiat. Biol. , vol.58 , pp. 813-825
    • Tates, A.N.1    Van Welie, M.T.2    Ploem, J.S.3
  • 36
    • 0027949609 scopus 로고
    • Scoring of radiation-induced micronuclei in cytokinesis-blocked human lymphocytes by automated image analysis
    • Verhaegen, F., Vrai, A., Seuntjens, J., Schipper, N.W., de Ridder, L., Thierens, H., 1994. Scoring of radiation-induced micronuclei in cytokinesis-blocked human lymphocytes by automated image analysis. Cytometry 17, 119-127.
    • (1994) Cytometry , vol.17 , pp. 119-127
    • Verhaegen, F.1    Vrai, A.2    Seuntjens, J.3    Schipper, N.W.4    De Ridder, L.5    Thierens, H.6
  • 37
    • 0023130992 scopus 로고
    • Measurement of micronuclei by cytokinesis-block method in cultured Chinese hamster cells: Comparison with types and rates of chromosome aberrations
    • Wakata, A., Sasaki, M.S., 1987. Measurement of micronuclei by cytokinesis-block method in cultured Chinese hamster cells: comparison with types and rates of chromosome aberrations. Mutation Res. 190, 51-57.
    • (1987) Mutation Res. , vol.190 , pp. 51-57
    • Wakata, A.1    Sasaki, M.S.2
  • 38
    • 0028226223 scopus 로고
    • Simultaneous detection of X-chromosome loss and non-disjunction in cytokinesis-blocked human lymphocytes by in situ hybridisation with a centromeric DNa probe; implications for the human lymphocyte in vitro micronucleus assay using cytochalasin-B
    • Zijno, A., Marcon, F., Leopardi, P., Crebelli, R., 1994. Simultaneous detection of X-chromosome loss and non-disjunction in cytokinesis-blocked human lymphocytes by in situ hybridisation with a centromeric DNA probe; implications for the human lymphocyte in vitro micronucleus assay using cytochalasin-B. Mutagenesis 9 (3), 225-232.
    • (1994) Mutagenesis , vol.9 , Issue.3 , pp. 225-232
    • Zijno, A.1    Marcon, F.2    Leopardi, P.3    Crebelli, R.4


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.